结胸证悉具，烦躁者死。
发热下利，厥逆，躁不得卧者死。
少阴病，吐利烦躁，四逆者死。
少阴恶寒而蜷，四逆脉不出，不烦而躁者死。
少阴六七日自利，复烦躁不得卧寐者死。
谓郁闷不舒畅也，无奈也，比之烦闷而甚。
由下后，表邪未解，阳邪内陷，结伏于心胸之间，邪热郁于胸中，宜栀子豉汤吐之。
或发汗吐下后，及阳明病下之，其外有热，手足温，不结胸，饥不饮食，头
汗，邪热结于胸中，宜承气茵陈下之。
阳明下之，胃中有燥屎，及阳明病无汗、小便不利、心懊 ，必发黄。
眠者，常睡熟也。不得眠者，虽睡不熟，且安静不烦也。卧者，欲睡着而复
醒也。不得卧者，欲安卧而烦闷不能安也。二者皆由汗吐下而生。胃虚则不得
眠。心虚则不得卧。汗吐下后不得眠，枝豉主之。日烦夜静，姜附主之。
不眠。少阴病，心烦不得眠，宜黄连阿胶汤。大热错语不眠，宜黄连解毒
汤。下利而渴不眠，宜猪苓汤利其水。吐下后，虚烦不得眠，酸枣仁汤导其热。
下后不眠同前。
不卧。身热目疼，不卧有汗，宜桂枝柴胡汤；无汗，宜麻黄加白虎。误服青
龙，汗多亡阳，先与防风白术牡蛎散，收其汗，次用小建中，养其心血。风温误
汗不卧者死。热病余热入心包络，不卧，宜知母麻黄汤小汗之，次用小柴胡乌梅
栀子汤，散心经之热，差后阴未复不卧，宜栀子乌梅汤。
结胸证的所有症状都已具备，如果出现烦躁不安的，属于死证。
发热并伴有下利，四肢厥冷，躁动不安无法躺卧的，属于死证。
少阴病，出现呕吐、下利、烦躁，且四肢逆冷的，属于死证。
少阴病恶寒而身体蜷缩，四肢逆冷且脉搏摸不到，不感到心烦但表现为躁动的，属于死证。
少阴病经过六七天自行下利，又出现烦躁、无法躺卧睡眠的，属于死证。
“懊”是指郁闷不舒畅，无可奈何，比一般的烦闷更为严重。
这是由于误用攻下法后，表邪未解，阳邪内陷，郁结伏留于心胸之间，邪热郁积在胸中，适宜用栀子豉汤（Zhi Zi Chi Tang, Gardenia and Fermented Soybean Decoction）通过涌吐的方法治疗。
或者在发汗、催吐、攻下之后，以及阳明病误用攻下法后，体表仍有发热，手足温暖，没有形成结胸，感到饥饿却不想进食，头部出汗，这是邪热结聚在胸中，适宜用承气茵陈（Cheng Qi Yin Chen, Rheum and Capillaris Decoction modified）通过泻下的方法治疗。
阳明病误用攻下法后，胃中有干燥的粪便，以及阳明病患者无汗、小便不利、心中懊恼，必定会出现发黄的症状。
“眠”是指经常睡得很熟。“不得眠”是指虽然想睡觉但睡不熟，且内心安静并不烦躁。“卧”是指想要睡着却又醒来。“不得卧”是指想要安稳躺卧却因烦闷而不能安卧。这两种情况（不得眠和不得卧）都是由发汗、催吐、攻下等治法不当引起的。胃气虚弱则导致不得眠。心气虚弱则导致不得卧。在发汗、催吐、攻下之后出现不得眠，用栀子豉汤主治。如果是白天烦躁夜间安静，用姜附（Jiang Fu, Ginger and Aconite Decoction）主治。
对于失眠：少阴病，心烦意乱无法入睡，适宜用黄连阿胶汤（Huang Lian E Jiao Tang, Coptis and Donkey-Hide Gelatin Decoction）。高热说胡话且失眠，适宜用黄连解毒汤（Huang Lian Jie Du Tang, Coptis Decoction for Detoxification）。下利且口渴导致失眠，适宜用猪苓汤（Zhu Ling Tang, Polyporus Decoction）利水。催吐、攻下之后，虚烦导致失眠，用酸枣仁汤（Suan Zao Ren Tang, Sour Jujube Seed Decoction）清导其热。攻下之后失眠同前所述。
对于无法安卧：身体发热、眼睛疼痛，无法安卧且有汗，适宜用桂枝柴胡汤（Gui Zhi Chai Hu Tang, Cinnamon Twig and Bupleurum Decoction）；无汗，适宜用麻黄加白虎（Ma Huang plus Bai Hu, Ephedra added to White Tiger Decoction）。如果误服大青龙汤（Da Qing Long Tang），导致汗出过多亡失阳气，先用防风白术牡蛎散（Fang Feng Bai Zhu Mu Li San, Saposhnikovia, Atractylodes and Oyster Shell Powder）收敛止汗，接着用小建中汤（Xiao Jian Zhong Tang, Minor Construct the Middle Decoction）滋养心血。风温病误用发汗法导致无法安卧的，属于死证。热病余热侵入心包络，导致无法安卧，适宜用知母麻黄汤（Zhi Mu Ma Huang Tang, Anemarrhena and Ephedra Decoction）微发其汗，接着用小柴胡乌梅栀子汤（Xiao Chai Hu Wu Mei Zhi Zi Tang, Minor Bupleurum, Dark Plum and Gardenia Decoction）疏散心经的热邪。病愈后阴液尚未恢复导致无法安卧，适宜用栀子乌梅汤（Zhi Zi Wu Mei Tang, Gardenia and Dark Plum Decoction）。
In the condition of Jie Xiong (Chest Binding), if all symptoms are present and irritability (Fan Zao) occurs, it is a fatal sign.
If there is fever accompanied by diarrhea, cold extremities (Jue Ni), and restlessness preventing lying down, it is a fatal sign.
In Shao Yin disease (Shaoyin Disease), if vomiting, diarrhea, irritability, and cold extremities occur, it is a fatal sign.
In Shao Yin disease, if there is aversion to cold with the body curled up, cold extremities, an imperceptible pulse, and although there is no mental agitation (Fan), there is physical restlessness (Zao), it is a fatal sign.
In Shao Yin disease, after six or seven days, if spontaneous diarrhea occurs again followed by irritability and inability to lie down or sleep, it is a fatal sign.
"Ao" refers to a state of depression and discomfort, feeling helpless, which is more severe than ordinary vexation.
This arises because after improper purgation, the exterior pathogen has not resolved, and the Yang pathogen has sunk inward, becoming trapped between the heart and chest, with evil heat stagnating in the chest. It is appropriate to use Zhi Zi Chi Tang (Gardenia and Fermented Soybean Decoction) to induce vomiting.
Alternatively, after sweating, vomiting, or purging, or after improper purgation in Yang Ming disease (Yangming Disease), if there is residual heat on the exterior, warm hands and feet, no formation of Jie Xiong, hunger without desire to eat, and sweating only on the head, this indicates evil heat binding in the chest. It is appropriate to use Cheng Qi Yin Chen (Rheum and Capillaris Decoction modified) to purge downward.
After improper purgation in Yang Ming disease, if there are dry feces in the stomach, or if Yang Ming disease presents with no sweating, difficult urination, and mental "Ao", jaundice will inevitably develop.
"Mian" refers to sleeping soundly. "Bu De Mian" (Insomnia/Inability to Sleep Soundly) means that although one attempts to sleep, it is not deep, yet the mind is quiet without vexation. "Wo" refers to attempting to fall asleep but waking up again. "Bu De Wo" (Inability to Lie Down Restfully) means desiring to lie down comfortably but being unable to do so due to vexation and discomfort. Both conditions arise from improper sweating, vomiting, or purging. Deficiency of the Stomach leads to Bu De Mian. Deficiency of the Heart leads to Bu De Wo. After sweating, vomiting, or purging, if Bu De Mian occurs, Zhi Zi Chi Tang is the primary treatment. If there is irritability during the day and calmness at night, Jiang Fu (Ginger and Aconite Decoction) is used.
For insomnia: In Shao Yin disease, if there is mental distress and inability to sleep, Huang Lian E Jiao Tang (Coptis and Donkey-Hide Gelatin Decoction) is appropriate. If high fever causes delirium and insomnia, Huang Lian Jie Du Tang (Coptis Decoction for Detoxification) is appropriate. If diarrhea with thirst causes insomnia, Zhu Ling Tang (Polyporus Decoction) is used to promote diuresis. After vomiting and purging, if deficiency-vexation causes insomnia, Suan Zao Ren Tang (Sour Jujube Seed Decoction) is used to guide out the heat. Insomnia following purgation is treated similarly as above.
For inability to lie down restfully: If there is body heat, eye pain, inability to lie down with sweating, Gui Zhi Chai Hu Tang (Cinnamon Twig and Bupleurum Decoction) is appropriate; if there is no sweating, Ma Huang added to Bai Hu Tang (Ephedra added to White Tiger Decoction) is appropriate. If Da Qing Long Tang (Major Green Dragon Decoction) is mistakenly taken, causing excessive sweating and loss of Yang Qi, first use Fang Feng Bai Zhu Mu Li San (Saposhnikovia, Atractylodes and Oyster Shell Powder) to stop sweating, then use Xiao Jian Zhong Tang (Minor Construct the Middle Decoction) to nourish Heart Blood. If Wind-Warmth disease is mistakenly treated with sweating, leading to inability to lie down, it is a fatal sign. If residual heat from a Heat Disease enters the Pericardium Meridian (Pericardium), causing inability to lie down, Zhi Mu Ma Huang Tang (Anemarrhena and Ephedra Decoction) is used to induce slight sweating, followed by Xiao Chai Hu Wu Mei Zhi Zi Tang (Minor Bupleurum, Dark Plum and Gardenia Decoction) to dissipate heat from the Heart Meridian. If inability to lie down persists after recovery due to incomplete restoration of Yin, Zhi Zi Wu Mei Tang (Gardenia and Dark Plum Decoction) is appropriate.