凡是表证法当汗之，根据法汗之，其病又不解。汗后不解，其证前后别无异证者，通宜凉膈散（二十
三）调之，以退其热，无使热甚危极也。除此之外，远胜小柴胡汤。两感至此而已，汗后余热用益元散
（五十二）、或小柴胡汤（九）、崔宣武人参石膏汤（三十六）。伤寒大发汗，汗出不解，反无汗，脉
尚浮者，苍术白虎汤（二十三）解之。伤寒用桂枝汤发汗后半日许，复热烦，脉浮者，再宜桂枝汤（二）；
汗后不解，下证未全者，白虎汤（二十三）；汗后烦躁不得眠，微热而渴，五苓散
（二十四）；汗后不解，里外有热，口干烦渴，柴胡饮子（四十七）；解表之后尚未
愈者，解毒（二十一）、凉膈（二十三）、天水散（五十二），能调顺阴阳，洗涤脏腑。
凡是里证法当下之，根据法下之，其病又不解。或大下后，或再三下后，热势尚甚而不退，本气虚
损而不能实，拟更下之，恐下脱而立死，不下之则热极而死，寒凉诸药不能退其热势之甚者；或湿热
内余，下利不止，热不退者；或因大下后，湿热利不止而热不退，脉弱气虚不可更下者；或诸湿热
内余，小便赤涩，大便溏泄，频并少腹而急痛者，必欲作痢也，通宜黄连解毒汤（二十一）以解之。
伤寒下之太过，胃中无热，饮水无力，白术散（四十二）。又有大下之后，其热不退，再三下之热愈甚，
若下之不止，其人脉微气虚，气弱不加，以法无可生之理。至此下之亦死、不下亦死，但用凉膈（二
十一）合解毒汤（二十三）调之，阳热退除，阴脉渐生，为之妙法。下之前后无问日数，余热不解，小
柴胡汤（九）。汗下后胃虚，大橘皮汤（三十九）。汗下后胸膈满闷，赤茯苓汤（四十）。
凡是表证，治法应当使用发汗法。如果按照常规发汗法治疗后，病情仍未解除。发汗后病情未解，且症状前后没有其他明显变化的，通常适宜用凉膈散（方剂编号二十三）来调理，以清除体内的热邪，防止热势过盛导致危重局面。除此之外，此法优于小柴胡汤。对于两感伤寒发展到此阶段的情况，若为发汗后的余热，可使用益元散（方剂编号五十二）、或小柴胡汤（方剂编号九）、崔宣武人参石膏汤（方剂编号三十六）。伤寒经过大发汗后，出汗但病不解，反而无汗，脉象仍然浮的，用苍术白虎汤（方剂编号二十三）来解除病邪。伤寒服用桂枝汤发汗后约半天时间，再次出现发热烦躁，脉象浮的，适宜再用桂枝汤（方剂编号二）；发汗后病情未解，而下证（里实热证）尚未完全形成的，用白虎汤（方剂编号二十三）；发汗后烦躁不能入睡，微热且口渴的，用五苓散（方剂编号二十四）；发汗后病情未解，表里都有热，口干烦躁口渴的，用柴胡饮子（方剂编号四十七）；解表之后病仍未愈的，可用解毒汤（方剂编号二十一）、凉膈散（方剂编号二十三）、天水散（方剂编号五十二），这些方剂能调和阴阳，清洗脏腑。
凡是里证，治法应当使用攻下法。如果按照常规攻下法治疗后，病情仍未解除。或者在大面积攻下之后，或反复多次攻下之后，热势依然严重而不消退，此时本气（正气）虚损而不能充实，打算再次攻下，恐怕会导致脱证而立即死亡，若不攻下则因热极而死，且寒凉药物无法退去严重的热势；或者是湿热内蕴残留，腹泻不止，热不退的；或者是因大攻下后，湿热导致的腹泻不止而热不退，脉弱气虚不可再次攻下的；或者是各种湿热内蕴残留，小便赤红涩痛，大便溏泄，频繁并伴有少腹拘急疼痛的，这必定是痢疾的前兆，通常适宜用黄连解毒汤（方剂编号二十一）来解除病邪。伤寒攻下太过，胃中没有热邪，饮水无力，用白术散（方剂编号四十二）。又有大攻下之后，热势不退，反复多次攻下后热势更甚，如果继续攻下不止，患者脉微气虚，元气虚弱无法补充，按常理已无生还希望。到了这一步，攻下也死，不攻下也死，只能使用凉膈散（方剂编号二十一）合解毒汤（方剂编号二十三）来调理，待阳热退除，阴脉逐渐恢复，这是巧妙的方法。无论攻下之前还是之后，不论经过多少天，余热未解的，用小柴胡汤（方剂编号九）。汗法和下法之后胃气虚弱，用大橘皮汤（方剂编号三十九）。汗法和下法之后胸膈满闷，用赤茯苓汤（方剂编号四十）。
For all exterior syndromes, the treatment method should be sweating. If, according to the standard sweating method, the disease remains unresolved after sweating, and there are no other significant changes in symptoms before and after, it is generally appropriate to regulate with Liangge San (Cooling the Diaphragm Powder) [Formula 23] to reduce heat, preventing it from becoming critically severe. Apart from this, it is far superior to Xiaochaihu Tang (Minor Bupleurum Decoction). For Lianggan (simultaneous involvement of Taiyang and Shaoyin or Yangming and Taiyin) reaching this stage, for residual heat after sweating, Yiyuan San (Benefit the Origin Powder) [Formula 52], or Xiaochaihu Tang [Formula 9], or Cui Xuanwu's Ginseng and Gypsum Decoction [Formula 36] may be used. After severe sweating in Shanghan (Cold Damage), if sweating occurs but the disease does not resolve, and instead there is no sweating with a still floating pulse, Cangzhu Baizhu Tang (Atractylodes Macrocephala and White Tiger Decoction) [Formula 23] should be used to resolve the pathogen. In Shanghan, half a day after taking Guizhi Tang (Cinnamon Twig Decoction) to induce sweating, if fever and irritability recur with a floating pulse, Guizhi Tang [Formula 2] should be administered again; if the disease remains unresolved after sweating but the interior excess syndrome (Xi Zheng) is not fully formed, Baihu Tang (White Tiger Decoction) [Formula 23] is indicated; if after sweating there is irritability, insomnia, slight fever, and thirst, Wuling San (Five-Ingredient Poria Pill) [Formula 24] is used; if after sweating the disease remains unresolved, with heat in both interior and exterior, dry mouth, irritability, and thirst, Chaihu Yinzi (Bupleurum Infusion) [Formula 47] is used; if after resolving the exterior the illness has not yet healed, Jiedu Tang (Detoxification Decoction) [Formula 21], Liangge San [Formula 23], or Tianshui San (Heavenly Water Powder) [Formula 52] can be used to harmonize Yin and Yang and cleanse the Zang-Fu organs.
For all interior syndromes, the treatment method should be purgation. If, according to the standard purgative method, the disease remains unresolved. Or after massive purgation, or repeated purgations, if the heat intensity remains severe and does not subside, while the root Qi (Zheng Qi) is deficient and unable to solidify, intending to purge again risks immediate death due to collapse from purgation; failing to purge leads to death from extreme heat, and cold-cooling herbs cannot reduce such severe heat; or if damp-heat remains internally causing persistent diarrhea without heat reduction; or if after massive purgation, damp-heat causes persistent diarrhea without heat reduction, and the pulse is weak with Qi deficiency making further purgation inadvisable; or if various damp-heats remain internally causing red and scanty urine, loose stools, frequent urgency, and acute pain in the lower abdomen, indicating impending dysentery (Li Ji), then Huanglian Jiedu Tang (Coptis Detoxification Decoction) [Formula 21] is generally appropriate to resolve the condition. If Shanghan is over-purgated, leaving no heat in the Stomach, resulting in inability to drink water effectively, Baizhu San (Atractylodes Macrocephala Powder) [Formula 42] is used. Furthermore, after massive purgation, if heat does not subside and repeated purgations make the heat worse, if purgation continues indefinitely, the patient presents with a faint pulse and Qi deficiency, where Qi weakness cannot be replenished, leaving no rational basis for survival according to standard methods. At this point, purging leads to death, and not purging also leads to death; only by using Liangge San [Formula 21] combined with Jiedu Tang [Formula 23] for regulation, allowing Yang-heat to retreat and Yin pulses to gradually regenerate, can a miraculous outcome be achieved. Regardless of whether it is before or after purgation, and irrespective of the number of days passed, if residual heat remains unresolved, Xiaochaihu Tang [Formula 9] is used. After sweating and purgation leading to Stomach deficiency, Daju Pi Tang (Large Tangerine Peel Decoction) [Formula 39] is used. After sweating and purgation leading to fullness and oppression in the chest and diaphragm, Chi Fuling Tang (Red Poria Decoction) [Formula 40] is used.