柴胡（四两） 龙骨 生姜（切） 人参 茯苓 铅丹 黄芩 牡蛎（熬） 桂枝（各一两半） 半夏（二合半，
洗） 大枣（六枚，擘） 大黄（二两） 上十二味，以水八升，煮取四升，纳大黄，切如棋子大，更煮一、二沸，大
黄只煮一、二沸，取其生而流利也，去渣，温服一升。
伤寒八、九日，下之，即陷入里。胸满，柴胡、黄芩。烦惊，龙骨、铅丹。牡蛎。小便不利，茯苓。谵
语，大黄。一身尽重，不能转侧者。茯苓。柴胡加龙骨牡蛎汤主之。此乃正气虚耗，邪已入里，而复外扰
三阳，故现症错杂，药亦随症施治，真神化无方者也。
按∶此方能下肝胆之惊痰，以之治癫痫必效。
柴胡（半斤） 桂枝（三两，去皮） 黄芩（三两） 干姜 牡蛎（熬） 甘草（炙，各二两） 栝蒌根（四两） 上
七味，以水一斗二升，煮取六升，去渣，再煎，取三升，温服一升，日三服，初服微烦，复服汗出便愈。邪气已深，
一时不能即出，如蒸蒸而振，发热汗出而解之类。
伤寒五、六日已发汗而复下之，一误再误。胸胁满，用牡蛎。微结，小便不利，渴，以上皆少阳症。渴，
故用栝蒌。而不呕，故去半夏生姜。但头汗出，阳气上越用牡蛎。往来寒热，用柴芩。心下烦者，黄芩、牡
蛎。此为未解也，柴胡桂枝干姜汤主之。
柴胡（四两） 龙骨 生姜（切片） 人参 茯苓 铅丹 黄芩 牡蛎（熬制） 桂枝（各一两半） 半夏（二合半，洗净） 大枣（六枚，掰开） 大黄（二两） 以上十二味药，用八升水，煮取四升药液，加入大黄，切成棋子大小的块，再煮沸一、两次。大黄只需煮一、两次，是为了取其生用而具有通利之性，滤去药渣，温服一升。
伤寒病经过八、九天，误用下法，邪气随即陷入体内。出现胸中胀满，用柴胡、黄芩；烦躁惊悸，用龙骨、铅丹、牡蛎；小便不利，用茯苓；谵语，用大黄；全身沉重，不能翻身转侧，用茯苓。主治方剂为柴胡加龙骨牡蛎汤。这是因为正气虚耗，邪气已入里，又向外扰动三阳经，所以症状错综复杂，用药也随症状灵活施治，真是神妙变化、不拘成法啊。
柴胡（半斤） 桂枝（三两，去皮） 黄芩（三两） 干姜 牡蛎（熬制） 甘草（炙，各二两） 栝蒌根（四两） 以上七味药，用一斗二升水，煮取六升药液，滤去药渣，再次煎煮，取三升药液，温服一升，每日三次。初次服药后微微感到烦闷，再次服药后出汗即可痊愈。邪气已经深入，一时不能立即排出，就像身体蒸蒸发热并伴有寒战，最终通过发热出汗而解除病情之类的情形。
伤寒病五、六天，已经发汗却又误用下法，一误再误。出现胸胁胀满，用牡蛎；轻微结滞，小便不利，口渴，以上都是少阳病的症状。因为口渴，所以用栝蒌；因为没有呕吐，所以去掉半夏和生姜。只有头部出汗，是阳气上越，用牡蛎；寒热往来，用柴胡、黄芩；心下部烦闷，用黄芩、牡蛎。这说明病邪尚未解除，主治方剂为柴胡桂枝干姜汤。
Chai Hu (Radix Bupleuri, four liang), Long Gu (Fossilized Bones, unspecified amount), Sheng Jiang (Rhizoma Zingiberis Recens, sliced), Ren Shen (Radix Ginseng, unspecified amount), Fu Ling (Poria, unspecified amount), Qian Dan (Lead Tetroxide, unspecified amount), Huang Qin (Radix Scutellariae, unspecified amount), Mu Li (Concha Ostreae, calcined), Gui Zhi (Ramulus Cinnamomi, one and a half liang each), Ban Xia (Rhizoma Pinelliae, two and a half he, washed), Da Zao (Fructus Jujubae, six pieces, split), Da Huang (Radix et Rhizoma Rhei, two liang). The above twelve ingredients are decocted in eight sheng of water to obtain four sheng of liquid. Add Da Huang, cut into pieces the size of chessmen, and boil for one or two more boils. Da Huang is only boiled for one or two boils to retain its raw property and promoting flow action. Strain the dregs, and take one sheng warm.
In Shaoyang disease (disease of the Shaoyang channel) after eight or nine days, if purgation is mistakenly applied, the pathogenic factor immediately sinks inward. Chest fullness is treated with Chai Hu and Huang Qin; irritability and palpitations are treated with Long Gu, Qian Dan, and Mu Li; difficulty in urination is treated with Fu Ling; delirium is treated with Da Huang; heaviness of the entire body with inability to turn over is treated with Fu Ling. The governing formula is Chai Hu Jia Long Gu Mu Li Tang (Bupleurum Plus Dragon Bone and Oyster Shell Decoction). This occurs because the healthy qi is depleted, the pathogenic factor has entered the interior, and yet disturbs the three yang channels externally. Therefore, the symptoms are complex and mixed, and the medication is administered flexibly according to the symptoms, demonstrating truly miraculous and unbounded efficacy.
Note: This formula can descend and dissipate phlegm from the liver and gallbladder caused by fright; it is effective for treating epilepsy.
Chai Hu (Radix Bupleuri, half jin), Gui Zhi (Ramulus Cinnamomi, three liang, bark removed), Huang Qin (Radix Scutellariae, three liang), Gan Jiang (Rhizoma Zingiberis, unspecified amount), Mu Li (Concha Ostreae, calcined), Gan Cao (Radix Glycyrrhizae, roasted, two liang each), Gua Lou Gen (Radix Trichosanthis, four liang). The above seven ingredients are decocted in one dou and two sheng of water to obtain six sheng of liquid. Strain the dregs, and decoct again to obtain three sheng of liquid. Take one sheng warm, three times a day. After the first dose, slight irritability may occur; after subsequent doses, sweating will occur and the patient will recover. When the pathogenic factor has penetrated deeply, it cannot be expelled immediately; this resembles cases where there is steaming heat accompanied by shaking/chills, ultimately resolving through fever and sweating.
After five or six days of Shaoyang disease (disease of the Shaoyang channel), if sweating has already been induced and then purgation is mistakenly applied, it is a second error. Chest and hypochondriac fullness is treated with Mu Li; slight binding/accumulation, difficulty in urination, and thirst are all symptoms of Shaoyang disease. Because of thirst, Gua Lou is used; because there is no vomiting, Ban Xia and Sheng Jiang are omitted. Sweating only on the head indicates upward floating of yang qi, treated with Mu Li; alternating chills and fever are treated with Chai Hu and Huang Qin; irritability in the epigastrium is treated with Huang Qin and Mu Li. This indicates the disease has not yet resolved. The governing formula is Chai Hu Gui Zhi Gan Jiang Tang (Bupleurum, Cinnamon Twig, and Dried Ginger Decoction).