[General Principle] Zhang Zhongjing stated: When the pulse is floating and surging, the body sweats like oil, panting does not cease, fluids cannot be taken in, the body is insensible (numbness), alternating between stillness and agitation, this indicates the exhaustion of life.

[Detailed Commentary] Zhang Yunqi said: "Insensibility" refers to a lack of flexibility, where pain and itch are unknown, and limbs can be bent or extended at will; even with moxibustion or acupuncture, there is no sensation. This is called "insensibility." It arises because pathogenic factors are abundant and excess, while righteous qi is blocked by these pathogens, becoming stagnant and unable to manifest. Consequently, blood and qi become deficient and fail to circulate. The *Neijing* states: "When Ying Qi (Nutritive Qi) is deficient, insensibility occurs." The *Zhenjing* (Classic of Acupuncture) states: "When Wei Qi (Defensive Qi) does not flow, insensibility occurs." Another classic says: "When Ying and Wei cannot coordinate, and the San Jiao (Triple Burner) has nothing to rely upon, the body suffers from Bi syndrome and insensibility." From this, it is clear that deficiency of Ying, Wei, blood, and qi, leading to failure of circulation, causes insensibility. Furthermore, it is said: "All conditions caused by cold invasion result in Jue (reversal/collapse), accompanied by Yu Mao (depression and dizziness) and insensibility." The "Jue" mentioned here refers to Qi reversal caused by righteous qi being overcome by cold, not the cold extremities seen in typical Jue syndromes. Why? Because "Yu Mao" implies mental confusion/dizziness, and "insensibility" implies loss of pain/itch sensation; together they constitute "Shi Jue" (Corpse-like Jue). The classics state: "When the Shaoyin pulse is absent, Kidney Qi is weak, and essence and blood are scant, rushing Qi forces its way up into the chest and diaphragm, Zong Qi (Gathering Qi) gathers inversely, blood coagulates below the heart, Yang Qi retreats downward, heat returns to the inner thighs, interacting with Yin, causing the body to become insensible. This is Shi Jue." Thus, the Jue, Yu Mao, and insensibility caused by cold invasion can be understood through this explanation. In the past, Bian Que entered the State of Guo and diagnosed the Crown Prince as suffering from Shi Jue. He considered the condition characterized by Yu Mao and insensibility treatable, cured him via acupuncture, proving himself a divine physician. However, if the condition were truly "exhaustion of life" as described in the main text, could even Bian Que save him?

Tao Hua said: During spasms, muscles contract tightly; during relaxation, they extend. Heat generates wind, and wind governs movement, causing muscle tendons to pull and cause contraction and extension. When Shanghan (Cold Damage) reaches this stage, it is a fatal syndrome. If one can dispel wind and purge heat, there may be a chance of survival. The treatment method is similar to that for Jing Bing (Spasm Disease). "Insensibility" refers to lack of flexibility. Various deficiency patterns combined with cold invasion lead to Yu Mao and insensibility. Due to deficiency of blood and qi, circulation throughout the body fails, allowing righteous qi to be subdued by pathogens, resulting in numbness and insensibility of the limbs, with cold reversal resembling a corpse. Use Mahui Banxia Tang (Cinnamon Twig, Ephedra, and Pinellia Decoction); if ineffective, use Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) with ginger juice.

Li Zhongzi said: Spasms (Yong Zhong) involve alternating contraction and extension, with irregular movements. If sweating occurs due to inadequate covering, leading to spasms of the waist, back, hands, and feet, use Niubanggen Tang (Arctium Root Decoction). If the pulse is floating and rapid indicating wind-heat, use Fangfeng Tongsheng San (Saposhnikovia Universal Relief Powder). If blood fails to nourish the tendons, use Da Qinjiao Tang (Large Gentian Decoction).