生地黄（一斤打碎） 栀子（二十枚擘） 升麻（三两） 柴胡 石膏（各五两）
上五味。以水八升。煮取三升。分五服。频频服。若不解。更服。若头面赤。去石膏。用干葛四两。无地黄。用豉
一升。煮取三升。分三服。
琥按上主疗云。三月至年末为晚发。乃知四时皆有伤寒病也。然年末系冬。为正伤寒。不得云晚发。则晚发当自
秋止矣。上方乃治少阳阳明二经燥热之剂。
治痰热头疼。利膈。除烦闷。手足烦热营卫不调。肢节拘倦。身体疼痛嗜卧少力饮食无味。兼治五饮。消痰癖。
柴胡（八两） 半夏（二两半洗） 白术 甘草（炙） 人参 黄芩 麦门冬（去心各三两）
上锉如麻豆大。每服钞五钱匕。水一盏半。生姜五片。枣子一枚。煮至八分。去滓温服。
琥按上方。即仲景小柴胡
汤中。加白术麦门冬也。推制方之意。以白术能燥脾。而治痰之本。麦冬能清肺而防热所伤。愚以痰热虽甚。方中既有
黄芩。则麦冬亦可以不用。况湿热之痰。非麦冬所能清也。据上主疗云。头疼体痛。膈间烦闷。当是风寒外来。热郁于
少阳之经而生痰。恐未必骤至于虚耳。方中若人参白术宜审用之。或者病已久。嗜卧少力。能饮食而无味。是为实证成
虚。如人参白术。不妨加用。然亦须以枳实陈皮等。相佐服之。
生地黄（一斤，捣碎） 栀子（二十枚，掰开） 升麻（三两） 柴胡 石膏（各五两）
以上五味药。用水八升。煮取三升药液。分五次服用。频繁服用。如果病不解，再服用。如果出现头面部发红，去掉石膏，改用干葛四两。如果没有地黄，用豆豉一升。煮取三升药液。分三次服用。
琥按：上述主治说明中提到，从三月到年末发病称为晚发。由此可知四季都有伤寒病。然而年末属于冬季，是正伤寒，不能称为晚发。那么晚发应当是从秋季开始止于年末。上面的方子是治疗少阳经和阳明经燥热的药剂。
治疗痰热引起的头痛。通利胸膈。消除烦闷。手足烦热、营卫不调。肢体关节拘急疲倦。身体疼痛、嗜睡、乏力、饮食无味。兼治五种饮邪。消除痰癖。
柴胡（八两） 半夏（二两半，洗净） 白术 甘草（炙） 人参 黄芩 麦门冬（去心，各三两）
以上药物锉成如麻豆大小的颗粒。每次取五钱匕的药量。加水一盏半。生姜五片。枣子一枚。煮至八分满。去渣后温服。
琥按：上面的方子，就是张仲景的小柴胡汤中，加入白术和麦门冬。推测制方的用意，是因为白术能燥脾，从而治疗生痰的根本；麦冬能清肺，防止热邪所伤。我认为虽然痰热很盛，但方中既有黄芩，那么麦冬也可以不用。况且湿热之痰，不是麦冬所能清除的。根据上述主治说明提到，头痛体痛、膈间烦闷，应当是风寒外来，热邪郁结在少阳经而生痰。恐怕未必一下子就到了虚证的程度。方中的人参和白术应该审慎使用。或者病情已久，嗜睡乏力，能吃但无味，这是实证转为虚证。如果是这样，用人参和白术不妨加上。但也必须配合枳实、陈皮等药物辅助服用。
[Formula by Zhang Wenzhong for Late-Onset Cold Damage, defined as onset from the third month to the end of the year]
Shengdi Huang (Rehmanniae Radix) (one jin, crushed) Zhizi (Gardeniae Fructus) (twenty fruits, split) Shengma (Cimicifugae Rhizoma) (three liang) Chaihu (Bupleuri Radix) Shigao (Gypsum Fibrosum) (each five liang)
The above five herbs. Use eight sheng of water. Boil to obtain three sheng of decoction. Divide into five doses. Take frequently. If the condition does not resolve, take more. If there is redness in the head and face, remove Shigao (Gypsum Fibrosum) and use Gan Ge (Puerariae Lobatae Radix) four liang. If Shengdi Huang (Rehmanniae Radix) is unavailable, use Chi Xiao Dou (Sojae Semen Praeparatum) one sheng. Boil to obtain three sheng of decoction. Divide into three doses.
Hu notes: The aforementioned indications state that onset from the third month to the end of the year is called late-onset. From this, we know that cold damage occurs in all four seasons. However, the end of the year belongs to winter, which is typical cold damage (Zheng Shanghan), and cannot be called late-onset. Therefore, late-onset should begin from autumn. The above formula is a preparation for treating dry-heat in the Shaoyang (Lesser Yang) and Yangming (Yang Brightness) meridians.
Treats headache caused by phlegm-heat. Benefits the diaphragm. Removes irritability and oppression. Treats vexing heat in the hands and feet, disharmony of Ying (Nutritive) and Wei (Defensive) Qi, stiffness and fatigue in limbs and joints, body pain, lethargy, weakness, and loss of taste. Also treats the five types of Yin pathologies (fluid retention). Eliminates phlegm masses.
Chaihu (Bupleuri Radix) (eight liang) Banxia (Pinelliae Rhizoma) (two and a half liang, washed) Baizhu (Atractylodis Macrocephalae Rhizoma) Gancao (Glycyrrhizae Radix et Rhizoma) (stir-fried with honey) Renshen (Ginseng Radix) Huangqin (Scutellariae Radix) Maidong (Ophiopogonis Radix) (decored, each three liang)
Crush the herbs to the size of hemp seeds. For each dose, take five qian bi (a small scoop measure). Add one and a half sheng of water, five slices of Shengjiang (Zingiberis Rhizoma), and one Zaozi (Jujubae Fructus). Boil until reduced to eight parts. Strain and take warm.
Hu notes: The above formula is essentially Zhang Zhongjing's Xiaochaihu Tang (Minor Bupleurum Decoction) with the addition of Baizhu (Atractylodis Macrocephalae Rhizoma) and Maidong (Ophiopogonis Radix). Inferring the intent of the formula's creation, Baizhu (Atractylodis Macrocephalae Rhizoma) can dry the Spleen and treat the root cause of phlegm production; Maidong (Ophiopogonis Radix) can clear the Lung and prevent injury by heat. I believe that although phlegm-heat is severe, since Huangqin (Scutellariae Radix) is already in the formula, Maidong (Ophiopogonis Radix) may be omitted. Moreover, damp-heat phlegm cannot be cleared by Maidong (Ophiopogonis Radix). According to the aforementioned indications mentioning headache, body pain, and diaphragmatic irritability, it should be due to external wind-cold, with heat constrained in the Shaoyang (Lesser Yang) meridian generating phlegm. It is unlikely that deficiency would develop suddenly. Renshen (Ginseng Radix) and Baizhu (Atractylodis Macrocephalae Rhizoma) in the formula should be used with caution. Or, if the disease has persisted for a long time, causing lethargy and weakness, with appetite but no taste, this indicates a transformation from excess syndrome to deficiency syndrome. In such cases, using Renshen (Ginseng Radix) and Baizhu (Atractylodis Macrocephalae Rhizoma) is acceptable. However, they must be taken in conjunction with drugs such as Zhishi (Aurantii Fructus) and Chenpi (Citri Reticulatae Pericarpium) as assistants.