不得眠阴阳皆有之正病于不得眠者阳明也若少阴当病于欲寐今乃不得眠缘阳气入少阴经非少阴正病也有因汗下而
然者有不因汗下而然者有因火逆而然者治见本条但不得眠皆为热证其有太阳汗下之后昼日燥躁不得眠一证虽用干姜附
子汤盖复其汗下所亡之阳非治其所感之寒病也不得眠为常证然少阴脉沉细自利烦躁不得眠者死伤寒发热下利厥逆烦躁
不得卧者亦死俱为正气弱阳不能复故也 活人云汗为火之液汗多则神昏故不眠大热则神不清故不眠大下则动血心主血
故不眠瘥后热气未散阴气未复故不眠
太阳 病二三日不得卧但欲起心下必结脉微弱者此有寒分也桂枝加浓朴杏子汤 伤寒脉浮以火劫之惊狂起卧不得
安者桂枝去芍药加蜀漆龙骨牡蛎救逆汤 下后复发汗昼日烦躁不得眠夜而安静不呕不渴无表证脉沉微身无大热干姜附
子汤 衄家不可汗汗则额上陷脉急紧直视不 不得眠(黄芩芍药汤)伤寒下后心烦腹满卧起不安者栀子浓朴汤 发汗吐
下后虚烦不得眠反复颠倒心中懊 栀子豆豉汤太阳病发汗后胃中干燥不得眠欲饮水者少与之则愈
阳明 身热目疼鼻干不得卧尺寸脉俱长者阳明受病也病患小便不利大便乍难乍易时有微热喘冒不能卧者有燥屎也
宜大承气汤 阳明病脉浮而紧咽燥口苦腹满而喘发热汗出不恶寒反恶热身重若加烧针必怵惕烦躁不眠宜栀子豉汤
少阴 病欲寐二三日后心烦不得卧者黄连阿胶汤主之
黄连阿胶汤方
黄连(四两) 黄芩(二两) 芍药(二两) 阿胶(三两) 鸡子黄(二枚)上五味
以水五升先煮三物取二升去滓纳胶熔尽少冷纳鸡子黄搅令和温服七合日三服(成 阳有余以苦除之黄连黄芩之苦以除热
阴不足以甘补之鸡子黄阿胶之甘以补血酸收也泄也芍药之酸收阴气而泄邪热也 然服鸡子黄其病有不愈者今议加当归
人参茯苓白术各等分与前药四味服之立效)
少阴病下利欲寐六七日后咳而呕渴心烦不得眠者宜猪苓汤(论见下利)少阴病但欲寐脉沉细不烦欲吐至五六日自利
复烦躁不得寐者死 发热下利厥逆烦躁不得卧者死
吴 太阳脉浮数身疼无汗烦躁不眠者宜汗之则愈 阳明标热头额痛目疼身热鼻干不得卧脉长者宜葛根解肌汤汗之
若自汗脉洪数表里俱热烦渴舌燥饮水者白虎加人参汤主之若蒸蒸发热大便秘硬者调胃承气汤下之外有伤寒已解或因食
复剧烦闷干呕口燥呻吟错语不得眠者黄连解毒汤主之若表里大热舌燥饮水者人参白虎汤合解毒汤主之 凡少阳发热口
苦心烦不得眠脉弦数者小柴胡加黄连山栀子之类若虚弱人津液不足者加麦门冬酸枣仁之类 太阳病发汗后不得眠脉浮
数微热烦渴小便不利者五苓散主之脉数大者人参白虎汤或竹叶石膏汤不可用五苓也 凡汗下后虚烦不得眠者加味温胆
汤酸枣仁汤栀子乌梅汤朱砂安神丸之类选而用之
附
酸枣仁汤 治虚烦扰奔气在胸中不得眠者
酸枣仁(炒) 人参 茯苓(各一钱半) 桂心(五分) 石膏(二钱半) 知母 甘草(各一钱) 生姜(三片)
上作一服水二钟煎至一钟去滓临卧服
千金流水汤 治虚烦不得眠
麦门冬(去心) 半夏 甘草 黄连 远志 人参 萆 (以上各一钱) 茯神 酸枣仁(各一钱半) 桂心(五
分) 生姜(三片) 米(一合)上用长流水二钟半先煮水令蟹目沸以杓扬万遍取汤二钟煎药至一钟去滓温服
加味温胆汤 治太阳病后虚烦不得眠此胆寒也
半夏(洗) 酸枣仁(炒各一钱半) 绿枳实 陈皮 甘草(各一钱) 人参(二钱半) 茯神(二钱) 竹茹(一
团) 生姜(三片)上用水二钟煎至一钟去滓温服若心烦内热者倍加黄连麦门冬若口燥舌干者去半夏加麦门冬五味子天
花粉若表热未清者加软苗柴胡若内虚大便自利者去枳实加白术茯苓若内实心烦颠倒者加山栀仁
酸枣汤 治吐下后昼夜不得眠
酸枣仁(炒二钱半) 麦门冬 茯神 当归身(各二钱) 甘草 知母 川芎(各一钱半) 干姜(三分) 生姜
(三片)上煎法同前
栀子乌梅汤
栀子 黄芩 甘草 人参 麦门冬(各一钱) 柴胡(二钱) 乌梅(二枚) 生姜(三片) 竹叶(十四片)上
煎法同前
黄连解毒汤\x 治大热干呕错语呻吟不得眠
黄连(二钱半) 黄芩 黄柏(各半两) 栀子(四个)水二盏半煎至一盏半去滓分二服
失眠(不得眠)是阴阳失调的常见病症,但主要归属于阳明病。如果属于少阴病,应当表现为想睡觉(欲寐),现在反而不能入睡,这是因为阳气进入少阴经,并非少阴病的正证。
有的因发汗或攻下后导致,有的不因发汗或攻下而致,有的因误用火疗逆乱所致,治疗方法见各相关条文。总之,失眠多属热证。其中有一种情况是太阳病发汗或攻下后,白天烦躁不安、不能入睡,虽然使用干姜附子汤,这是为了恢复因汗下而亡失的阳气,而非治疗所感受的寒邪。
失眠虽是常见证候,但如果少阴病患者出现脉沉细、自利(腹泻)、烦躁、不能入睡,则预后不良,主死。伤寒发热、下利、四肢厥冷、烦躁、不能卧倒者,也主死。这都是因为正气虚弱,阳气无法回复的缘故。
《活人书》说:汗是火的液体,汗出过多则神志昏蒙,所以不眠;大热则神志不清,所以不眠;大下则动血,心主血脉,所以不眠;病愈后热气未散、阴气未复,所以不眠。
【太阳病】
太阳病二三日,不能卧,只想起身,心下部必然痞结,脉象微弱者,此为有寒分(寒邪凝滞)。用桂枝加浓朴杏子汤。
伤寒脉浮,被火法劫迫,出现惊狂、起卧不安者,用桂枝去芍药加蜀漆龙骨牡蛎救逆汤。
攻下后又发汗,白天烦躁不能入睡,夜间安静,不呕、不渴、无表证,脉沉微,身体无明显大热者,用干姜附子汤。
经常鼻衄的人不可发汗,若发汗则额部凹陷、脉紧急、直视、不能入睡(用黄芩芍药汤)。
发汗、吐、下后,虚烦、不能入睡、反复颠倒、心中懊恼者,用栀子豉汤。
太阳病发汗后,胃中干燥导致不能入睡,想喝水者,少量给予水喝即可痊愈。
【阳明病】
身体发热、目痛、鼻干、不能卧,寸关尺三部脉都长者,为阳明经受病。患者小便不利,大便乍难乍易,时有微热,喘促头眩不能卧者,体内有燥屎,宜用大承气汤。
阳明病,脉浮紧,咽干口苦,腹满而喘,发热汗出,不恶寒反恶热,身体沉重,若再加烧针,必致惊恐惕怍、烦躁不眠,宜用栀子豉汤。
【少阴病】
少阴病,想睡觉,两三天后心烦、不能卧者,主治用黄连阿胶汤。
黄连阿胶汤方:
黄连(四两)、黄芩(二两)、芍药(二两)、阿胶(三两)、鸡子黄(两枚)。以上五味药,用水五升,先煮前三味,取汁二升,去渣,纳入阿胶溶化尽,稍凉后纳入鸡子黄,搅匀,温服七合,每日三次。(成无己注:阳有余以苦除之,黄连、黄芩之苦以除热;阴不足以甘补之,鸡子黄、阿胶之甘以补血;酸收也,泄也,芍药之酸收阴气而泄邪热也。然而服用鸡子黄后病有不愈者,现建议加入当归、人参、茯苓、白术各等分,与前药四味同服,立竿见影。)
少阴病下利,想睡觉,六七天后感冒咳嗽、呕吐、口渴、心烦、不能眠者,宜用猪苓汤(论述见下利条)。少阴病但想睡觉,脉沉细,不烦,想吐,至五六日自利又烦躁不能寐者,主死。发热、下利、四肢厥冷、烦躁、不能卧者,主死。
吴氏指出:太阳病,脉浮数,身疼无汗,烦躁不眠者,宜发汗则愈。阳明标热,头额痛、目痛、身热、鼻干、不能卧,脉长者,宜葛根解肌汤发汗。若自汗、脉洪数、表里俱热、烦渴舌燥、饮水者,主治用白虎加人参汤。若蒸蒸发热、大便秘硬者,用调胃承气汤攻下。外感伤寒已解,或因饮食复发加重,烦闷干呕、口燥呻吟、错语、不能眠者,主治用黄连解毒汤。若表里大热、舌燥饮水者,用人参白虎汤合解毒汤主治。凡少阳病发热、口苦、心烦、不能眠,脉弦数者,用小柴胡汤加黄连、山栀子之类。若体虚津液不足者,加麦门冬、酸枣仁之类。太阳病发汗后,不能眠,脉浮数、微热、烦渴、小便不利者,主治用五苓散。脉数大者,用人参白虎汤或竹叶石膏汤,不可用五苓散。凡汗下后虚烦不能眠者,选用加味温胆汤、酸枣仁汤、栀子乌梅汤、朱砂安神丸等。
附录:
酸枣仁汤:治虚烦扰攘,奔气在胸中不能眠者。
酸枣仁(炒)、人参、茯苓(各一钱半)、桂心(五分)、石膏(二钱半)、知母、甘草(各一钱)、生姜(三片)。以上作一服,水二钟,煎至一钟,去渣,临睡前服。
千金流水汤:治虚烦不能眠。
麦门冬(去心)、半夏、甘草、黄连、远志、人参、萆薢(以上各一钱)、茯神、酸枣仁(各一钱半)、桂心(五分)、生姜(三片)、米(一合)。以上用长流水二钟半,先煮水令蟹眼沸,以勺扬万遍取汤二钟,煎药至一钟,去渣,温服。
加味温胆汤:治太阳病后虚烦不能眠,此乃胆寒所致。
半夏(洗)、酸枣仁(炒,各一钱半)、绿枳实、陈皮、甘草(各一钱)、人参(二钱半)、茯神(二钱)、竹茹(一团)、生姜(三片)。以上用水二钟,煎至一钟,去渣,温服。若心烦内热者,倍加黄连、麦门冬;若口燥舌干者,去半夏,加麦门冬、五味子、天花粉;若表热未清者,加软苗柴胡;若内虚大便自利者,去枳实,加白术、茯苓;若内实心烦颠倒者,加山栀仁。
酸枣汤:治吐下后昼夜不能眠。
酸枣仁(炒,二钱半)、麦门冬、茯神、当归身(各二钱)、甘草、知母、川芎(各一钱半)、干姜(三分)、生姜(三片)。煎法同上。
栀子乌梅汤:
栀子、黄芩、甘草、人参、麦门冬(各一钱)、柴胡(二钱)、乌梅(二枚)、生姜(三片)、竹叶(十四片)。煎法同上。
黄连解毒汤:治大热、干呕、错语、呻吟、不能眠。
黄连(二钱半)、黄芩、黄柏(各半两)、栀子(四个)。水二盏半,煎至一盏半,去渣,分两次服。
Insomnia (Bude Mian) is a common manifestation of yin-yang imbalance, but it primarily belongs to Yangming disease. If it were Shaoyin disease, the patient should manifest drowsiness (Yumi); the fact that they cannot sleep now indicates that yang qi has entered the Shaoyin meridian, which is not the typical presentation of Shaoyin disease.
Some cases arise after sweating or purging, some occur without such interventions, and some result from iatrogenic errors with fire therapy; treatments are detailed in their respective sections. Generally, insomnia is associated with heat syndromes. One specific case involves daytime restlessness and insomnia following sweating or purging in Taiyang disease. Although Ganjiang Fuzi Tang is used here, its purpose is to restore yang qi lost due to excessive sweating/purging, rather than to treat contracted cold pathogens.
While insomnia is a common symptom, if a Shaoyin patient presents with deep and fine pulse, spontaneous diarrhea, irritability, and inability to sleep, the prognosis is poor (death). Similarly, in Shanghan (Cold Damage), fever accompanied by diarrhea, cold extremities, irritability, and inability to lie down also indicates death. These conditions arise because righteous qi is weak and yang qi cannot recover.
The *Huoren Shu* states: Sweat is the fluid of fire; excessive sweating leads to clouded spirit, causing insomnia. Extreme heat causes unclear spirit, leading to insomnia. Severe purging damages blood; since the Heart governs blood, this causes insomnia. After recovery, if pathogenic heat has not dissipated and yin qi has not recovered, insomnia occurs.
[Taiyang Disease]
In Taiyang disease, if for two to three days the patient cannot lie down but wishes to rise, there must be stagnation in the epigastrium. With a faint pulse, this indicates cold accumulation. Use Guizhi Jia Houpo Xingzi Tang.
In Shanghan, if the pulse is floating and the patient is subjected to fire therapy, resulting in panic, mania, and restless tossing and turning, use Guizhi Qu Shaoyao Jia Shujie Longgu Muli Jiuni Tang.
After purging followed by sweating, if the patient is irritable and unable to sleep during the day but quiet at night, without vomiting, thirst, or exterior signs, with a deep and faint pulse and no significant body heat, use Ganjiang Fuzi Tang.
Patients prone to epistaxis should not undergo sweating; if sweated, they may experience sunken temples, tight pulse, fixed gaze, and insomnia (treated with Huangqin Shaoyao Tang).
After purging in Shanghan, if the patient has vexation, abdominal fullness, and restlessness, use Zhizi Houpo Tang.
After sweating, vomiting, or purging, if there is deficiency vexation, insomnia, tossing and turning, and inner discomfort (Aoni), use Zhizi Chidui Tang.
After sweating in Taiyang disease, if dryness in the stomach causes insomnia and thirst, giving small amounts of water will cure it.
[Yangming Disease]
Body heat, eye pain, nasal dryness, and inability to lie down, with long pulses at all three positions, indicate Yangming disease involvement. If the patient has difficulty urinating, alternating difficulty and ease in defecation, slight fever, wheezing, dizziness, and inability to lie down, there is dry stool in the intestines; use Dachengqi Tang.
In Yangming disease, with floating and tight pulse, dry throat, bitter taste, abdominal fullness, wheezing, fever, sweating, aversion to heat (not cold), and heavy body, if moxibustion is added, it will cause fright, irritability, and insomnia; use Zhizi Chi Tang.
[Shaoyin Disease]
In Shaoyin disease, if the patient desires sleep but after two to three days develops vexation and insomnia, treat with Huanglian Ejiao Tang.
Huanglian Ejiao Tang Formula:
Huanglian (4 liang), Huangqin (2 liang), Shaoyao (2 liang), Ejiao (3 liang), Ji Zi Huang (2 yolks). Boil the first three herbs in 5 sheng of water to obtain 2 sheng, strain, dissolve the Ejiao, let cool slightly, then mix in the egg yolks. Take 7 he warm, three times daily. (Cheng Wuji notes: Bitterness removes excess yang; Huanglian and Huangqin clear heat. Sweetness tonifies insufficient yin; Egg yolk and Ejiao nourish blood. Sourness astringes and drains; Shaoyao astringes yin and drains pathogenic heat. However, if illness persists after taking egg yolk, add Danggui, Renshen, Fuling, and Baizhu in equal parts to the previous four ingredients for immediate effect.)
If Shaoyin disease involves diarrhea, drowsiness, and after six to seven days presents with cough, vomiting, thirst, vexation, and insomnia, use Zhu Ling Tang (see Diarrhea section). If Shaoyin disease presents with drowsiness, deep and fine pulse, no vexation, desire to vomit, and progresses to spontaneous diarrhea with irritability and insomnia by the fifth or sixth day, the prognosis is death. Fever with diarrhea, cold extremities, irritability, and inability to lie down also indicates death.
Wu states: In Taiyang disease, with floating and rapid pulse, body ache, absence of sweat, irritability, and insomnia, induce sweating to cure. For Yangming superficial heat with headache, eye pain, body heat, nasal dryness, and long pulse, use Gegen Jiemo Tang to induce sweating. If there is spontaneous sweating, flooding and rapid pulse, interior-exterior heat, vexation, thirst, dry tongue, and desire to drink, use Baihu Jia Renshen Tang. If there is steaming heat and hard constipation, use Tiaowei Chengqi Tang to purge. If external Shanghan has resolved but worsens due to dietary indiscretion, causing stuffiness, dry retching, dry mouth, groaning, delirium, and insomnia, use Huanglian Jiedu Tang. If there is severe interior-exterior heat, dry tongue, and thirst, use Renshen Baihu Tang combined with Jiedu Tang. For Shaoyang fever, bitter taste, vexation, insomnia, and wiry-rapid pulse, use Xiao Chaihu Tang plus Huanglian and Shanzhizi. For deficient patients with insufficient fluids, add Maidong and Suanzaoren. After sweating in Taiyang disease, if insomnia occurs with floating-rapid pulse, slight fever, vexation, thirst, and dysuria, use Wuling San. If the pulse is large and rapid, use Renshen Baihu Tang or Zhuye Shigao Tang; do not use Wuling San. For deficiency vexation and insomnia after sweating/purging, select from Jiawei Wendan Tang, Suanzaoren Tang, Zhizi Wumei Tang, or Zhusha Anshen Wan.
Appendix:
Suanzaoren Tang: Treats deficiency vexation, rushing qi in the chest, and insomnia.
Suanzaoren (fried), Renshen, Fuling (1.5 qian each), Guixin (0.5 qian), Shigao (2.5 qian), Zhimu, Gancao (1 qian each), Shengjiang (3 slices). Decoct one dose in 2 zhong of water to 1 zhong, strain, and take before bed.
Qianjin Liushui Tang: Treats deficiency vexation and insomnia.
Maidong (decored), Banxia, Gancao, Huanglian, Yuanzhi, Renshen, Bibi (1 qian each), Fushen, Suanzaoren (1.5 qian each), Guixin (0.5 qian), Shengjiang (3 slices), Rice (1 he). Boil running water in 2.5 zhong until crab-eye bubbles form, stir with ladle ten thousand times to obtain 2 zhong of water, decoct herbs to 1 zhong, strain, and take warm.
Jiawei Wendan Tang: Treats deficiency vexation and insomnia after Taiyang disease, caused by Gallbladder cold.
Banxia (washed), Suanzaoren (fried, 1.5 qian each), Lv Zhishi, Chenpi, Gancao (1 qian each), Renshen (2.5 qian), Fushen (2 qian), Zhuru (one ball), Shengjiang (3 slices). Decoct in 2 zhong water to 1 zhong, strain, and take warm. If vexation and internal heat exist, double Huanglian and Maidong. If dry mouth and tongue, remove Banxia and add Maidong, Wuweizi, and Tianhuafen. If exterior heat remains, add Ruanmiao Chaihu. If interior deficiency with spontaneous diarrhea, remove Zhishi and add Baizhu and Fuling. If interior excess with vexation and tossing, add Shanzhiren.
Suanzaoren Soup: Treats insomnia day and night after vomiting/purging.
Suanzaoren (fried, 2.5 qian), Maidong, Fushen, Dangguishen (2 qian each), Gancao, Zhimu, Chuanxiong (1.5 qian each), Ganjiang (0.3 qian), Shengjiang (3 slices). Decoct as above.
Zhizi Wumei Tang:
Zhizi, Huangqin, Gancao, Renshen, Maidong (1 qian each), Chaihu (2 qian), Wumei (2 fruits), Shengjiang (3 slices), Zhuye (14 leaves). Decoct as above.
Huanglian Jiedu Tang: Treats extreme heat, dry retching, delirium, groaning, and insomnia.
Huanglian (2.5 qian), Huangqin, Huangbai (0.5 liang each), Zhizi (4 fruits). Decoct in 2.5 zhan water to 1.5 zhan, strain, and divide into two doses.