胸胁痛耳聋尺寸脉俱弦者少阳受病也(论见大法活人云柴胡汤主之)
病胸中诸实胸中郁郁而痛不能食欲使人按之而反有涎唾下利十余行其脉反迟寸口脉微滑此可吐之利(则止)
吐下后 欲吐胸中痛大便溏腹满而烦者宜调胃承气汤(详呕)
耳聋有二一由重发汗虚一由少阳中风 胸胁痛耳聋尺寸脉俱弦者少阳受病也
未持脉时病患又手自冒心试教令咳而不咳者此必耳聋无闻所以然者以重发汗虚故如此(黄 建中汤)少阳中风两耳
无闻目赤胸满而烦者不可吐下吐下则悸而惊(或用小柴胡汤)
少阳与厥阴俱病耳聋囊缩而厥者此两感证 厥阴荣卫不通耳聋囊缩不知人危矣 湿温证治在太阴不可汗汗则不能
言耳聋不知病处身青面色变名曰重 (白虎加苍术汤)
阳毒之证初受病时所加邪毒深重加以当汗失汗当下失下或吐下后邪热乘虚而入误服热药使毒热散漫如抱薪救火无
不延燎至于六脉沉实舌卷焦黑鼻中如烟煤身面锦斑狂言直走逾垣上屋登高而歌弃衣而走皆其证也五日可治六七日不可
治
升麻鳖甲汤 治阳毒为病面赤斑斑如锦纹咽喉痛唾脓血
升麻(二两) 当归 蜀椒(炒去汗) 甘草(各一两) 鳖甲(手指大一片) 雄黄(研半两)上六味以水四升
煮取一升顿服之取汗愈肘后千金方阳毒升麻汤有桂无鳖甲阴毒甘草汤无雄黄
附
活 阳毒升麻汤 治伤寒一二日便成阳毒或服药吐下之后变成阳毒腰背痛烦闷不安面赤狂言奔走或见鬼或下
利脉浮大数面赤斑斑如锦纹咽喉痛下脓血五日可治六七日不可治
升麻 犀角(镑) 射干 黄芩 人参 甘草(各等分) 上 咀水煎服食顷再服温覆手足出汗解不解重作
阳毒栀子汤 治阳毒伤寒发热百节疼痛
升麻 黄芩 杏仁 石膏(各二钱) 栀子 赤芍药 知母 大青(各一钱) 甘草(五分) 柴胡(一钱半)上
咀每服半两姜五片豉百粒同煎
大黄散 治阳毒伤寒未解热在内恍惚如狂
大黄(一两半) 桂心(七钱半) 甘草(炙) 芒硝 大腹皮 木通(各一两) 桃仁(二十一枚)上 咀水煎
服以利为度
海 葛根散 治阳毒身热如火头痛躁渴咽喉干痛
葛根(七钱半) 黄芩 大黄(醋炒) 甘草 栀子 朴硝(各半两)上 咀水煎服
活 黑奴丸 治时行病六七日未得汗脉洪大或数面赤目痛身体大热烦躁狂言欲走大渴甚又五六日以上不解热在胸
中口噤不能言为坏伤寒医所不治或人精魄已竭心下尚暖拨开其口灌药下咽即活兼治阳毒及发斑
麻黄(去节泡三两) 大黄(二两) 釜底煤(研) 黄芩 芒硝 灶突墨(研) 梁上尘 小麦奴(各一两)上
为末炼蜜丸如弹子大新汲水研下一丸渴者与冷水尽饮之须臾当寒寒竟汗出便瘥若无汗再服一丸须微利效小麦奴即小麦
未熟时丛中不成麦捻之成黑勃是也此药须是病患大渴倍常躁盛者乃可与之若不渴者服之反为祸耳
脉洪大内外结热舌卷焦黑鼻中如烟煤以水渍布薄之叠布数重新水渍之稍 去水搭于胸上须臾蒸热又渍冷如前薄之
仍换新水数十易热甚者置病患于水中势才退则已亦一良法也
丹砂丸 治伤寒阴阳二毒危恶形证
舶上硫 水银 太阴元精石 太阳石(各一两) 硝石(半两)上为末用无油铫子以文武火炒上项药令匀如灰色研
极细生姜自然汁浸炊饼丸如绿豆大每服五丸龙脑生姜蜜水下压其躁也若阳毒枣汤下阴毒白汤下不许于屋底炒
白虎加人参名化斑汤斑盛者青黛一物汤咽痛元参升麻汤
青黛一物汤
青黛(如枣大一块)用新汲水研服
玄参升麻汤
升麻 玄参 甘草(各半两) 水三盏煎一盏半去滓服
陶 阳毒伤寒服药不效斑烂皮肤手足皮俱脱身如涂朱眼珠如火躁渴欲死脉洪大而有力昏不知人宜三黄石膏汤主之
或升麻栀子汤吐之 若热甚时狂时昏口噤切牙药不可下者用水渍法候牙宽狂乱稍定投药亦良如黑奴丸不可轻用
活 阳气独胜阴气暴绝必发躁狂走妄言面赤咽痛发斑或下者利赤黄脉洪实或滑促宜酸苦之药救阴阳毒轻者桔梗大
黄汤 阳毒升麻汤 栀子仁汤 又龙胆草一物汤
赵 阳根于阴阴根于阳无阳则阴无以化无阴则阳无以生可见两者不能相无也又仲景云阳气先绝阴气后绝此人死身
色必青阴气前绝阳气后竭此人死身色必赤则知阴阳二气在人身中不可偏绝绝则无复生之理今活人书论阴毒而曰阳气绝
论阳毒而曰阴气绝既绝矣是为不治之证又何药焉盖阴阳二证之深重也又挟毒瓦斯是为阴毒阳毒故其药皆用升麻犀角雄黄
大青辈以解其毒然后阳毒泄而阴气复阴毒泄而阳气复大汗出而解矣活人书何不曰阳气极盛阴气极微为阳毒阴气极盛阳
气极微为阴毒庶不为极绝之证
胸胁疼痛、耳聋,且寸脉和尺脉都呈现弦象的,是少阳经受邪所致(相关论述见《活人书》,主张用柴胡汤主治)。
病邪结聚于胸中形成实证,患者感到胸中郁结疼痛,无法进食,让人按压胸部反而流出涎唾,伴有腹泻十余次,此时脉象反而迟缓,寸口脉微而滑,这种情况可以使用吐法治疗,腹泻就会停止。
在呕吐或泻下治疗后,患者想呕吐、胸中疼痛、大便溏薄、腹部胀满且心烦,适宜使用调胃承气汤(详细情况参见“呕”条)。
耳聋有两种成因:一种是由于过度发汗导致正气虚弱;另一种是少阳中风。胸胁疼痛、耳聋,且寸脉和尺脉都呈现弦象的,是少阳经受邪所致。
医生在未诊脉时,看到病人用手捂住心口,让病人咳嗽却不咳,这必定是因为耳聋听不见指令。之所以这样,是因为过度发汗导致正气虚弱的缘故(可用黄芪建中汤)。少阳中风,两耳听不见,眼睛发红,胸中满闷且心烦,不可使用吐法和下法,如果误用吐下法,会导致心悸和惊恐(可酌情使用小柴胡汤)。
少阳经与厥阴经同时发病,出现耳聋、睾丸收缩和四肢厥冷,这是两感证。厥阴经营卫之气不通,出现耳聋、睾丸收缩、神志不清,病情危重。湿温证的治疗原则在于太阴经,不可发汗,如果发汗则会导致不能说话、耳聋、不知病痛所在、身体发青、面色改变,这种情况称为“重”(可用白虎加苍术汤)。
阳毒的病症,在初受病时邪毒深重,加上该发汗时未发汗、该泻下时未泻下,或者在吐下之后邪热乘虚而入,误服热药使毒热散漫,如同抱薪救火,无不蔓延燃烧。症状表现为六脉沉实,舌体卷缩焦黑,鼻孔如烟煤状,身面出现如锦缎般的红斑,胡言乱语,奔跑跳跃,翻墙越屋,登高歌唱,脱衣奔走,这些都是其证候表现。发病五天内可治,六七天以上则不可治。
升麻鳖甲汤:治疗阳毒病,面部赤红,斑纹如锦缎般分布,咽喉疼痛,吐出脓血。
药物组成:升麻(二两)、当归、蜀椒(炒去汗)、甘草(各一两)、鳖甲(手指大小一片)、雄黄(研细半两)。以上六味药,用水四升,煮取一升,一次性服用,出汗即愈。《肘后备急方》和《千金方》中的阳毒升麻汤含有桂枝而无鳖甲;阴毒甘草汤不含雄黄。
附注:
《活人书》阳毒升麻汤:治疗伤寒一二日便成为阳毒,或服药后经过吐下变成阳毒,腰背疼痛,烦闷不安,面部赤红,胡言乱语,奔走,或看见鬼怪,或腹泻,脉浮大数,面部赤红,斑纹如锦缎般分布,咽喉疼痛,吐出脓血。发病五天内可治,六七天以上则不可治。
药物组成:升麻、犀角(镑片)、射干、黄芩、人参、甘草(各等分)。以上药物切碎,水煎服,间隔一顿饭的时间再服一次,温覆身体使手足出汗,若病不解,重新制作服用。
阳毒栀子汤:治疗阳毒伤寒,发热,全身关节疼痛。
药物组成:升麻、黄芩、杏仁、石膏(各二钱)、栀子、赤芍药、知母、大青(各一钱)、甘草(五分)、柴胡(一钱半)。以上药物切碎,每次服用半两,加生姜五片、豆豉百粒同煎。
大黄散:治疗阳毒伤寒未解,热邪在内,神情恍惚如狂。
药物组成:大黄(一两半)、桂心(七钱半)、甘草(炙)、芒硝、大腹皮、木通(各一两)、桃仁(二十一枚)。以上药物切碎,水煎服,以大便通畅为度。
海藏先生葛根散:治疗阳毒,身体发热如火,头痛,烦躁口渴,咽喉干燥疼痛。
药物组成:葛根(七钱半)、黄芩、大黄(醋炒)、甘草、栀子、朴硝(各半两)。以上药物切碎,水煎服。
《活人书》黑奴丸:治疗时行病六七天未能出汗,脉洪大或数,面部赤红,眼睛疼痛,身体大热,烦躁,胡言乱语,想要奔跑,极度口渴。又治疗五六日以上热邪仍在胸中,牙关紧闭不能说话,属于坏伤寒,医生认为无法治疗,或者病人精气已竭但心下尚暖的情况,拨开嘴巴灌药,药液咽下即可复活。兼治阳毒及发斑。
药物组成:麻黄(去节,浸泡,三两)、大黄(二两)、釜底煤(研细)、黄芩、芒硝、灶突墨(研细)、梁上尘、小麦奴(各一两)。以上药物研为末,炼蜜制成如弹子大的丸剂。用新汲取的冷水研磨一丸服用,口渴者给冷水喝尽。须臾之间应当感到寒冷,寒战结束后出汗即痊愈。若无汗,再服一丸,轻微腹泻也有效。“小麦奴”是指小麦未成熟时,丛中不成穗的小麦,捻之呈黑色勃发状。此药必须用于病人极度口渴、比平时更躁盛的情况才可给予,如果不渴,服用反而有害。
脉象洪大,内外结热,舌体卷缩焦黑,鼻孔如烟煤状,用水浸湿布巾敷贴,多层布叠起,重新浸湿冷水,稍干后将水搭在胸上,须臾后蒸热,再像前法浸湿冷水敷贴,仍更换新水数十次。热势甚者,可将病人置于水中,热势刚退即可停止,这也是一种良法。
丹砂丸:治疗伤寒阴阳二毒危重的证候。
药物组成:舶上硫磺、水银、太阴元精石、太阳石(各一两)、硝石(半两)。以上药物研为末,用无油的锅具,用文武火炒上述药物使其均匀如灰色,研极细。用生姜自然汁浸泡炊饼,制成如绿豆大的丸剂。每次服用五丸,用龙脑、生姜、蜂蜜水送下,以压制躁动。若是阳毒用枣汤送下,阴毒用白水送下。不允许在屋檐底下炒制。
白虎加人参汤又名化斑汤。斑疹严重者用青黛一物汤。咽喉痛用玄参升麻汤。
青黛一物汤:
药物组成:青黛(如枣大一块)。用新汲取的冷水研磨后服用。
玄参升麻汤:
药物组成:升麻、玄参、甘草(各半两)。水三盏,煎至一盏半,去渣服用。
陶华:阳毒伤寒服药无效,斑烂皮肤,手足皮俱脱落,身体如涂朱砂,眼珠如火,烦躁口渴欲死,脉洪大而有力,昏不知人,适宜用三黄石膏汤主治。或者用升麻栀子汤催吐。若热势甚时,时而狂乱时而昏沉,牙关紧闭咬切牙齿,药物无法下咽者,用水渍法,待牙关松开,狂乱稍定,投药亦良好,如黑奴丸不可轻用。
李杲:阳气独胜,阴气暴绝,必然发生烦躁、狂走、妄言、面部赤红、咽喉疼痛、发斑,或者腹泻赤黄色稀便,脉象洪实或滑促,适宜用酸苦性质的药物救治。阴阳毒轻症可用桔梗大黄汤、阳毒升麻汤、栀子仁汤,又有龙胆草一物汤。
赵嗣真:阳根于阴,阴根于阳,没有阳则阴无法化生,没有阴则阳无法生成,可见两者不可偏废。又张仲景说:阳气先绝,阴气后绝,此人必死,身体颜色必青;阴气先绝,阳气后竭,此人必死,身体颜色必赤。由此可知阴阳二气在人体中不可偏绝,一旦偏绝则无复生之理。如今《活人书》论阴毒时说“阳气绝”,论阳毒时说“阴气绝”,既然已经绝了,就是不治之证,还有什么药呢?大概是因为阴阳二证深重,又挟带毒瓦斯,所以称为阴毒、阳毒。因此用药都用升麻、犀角、雄黄、大青之类来解毒,然后阳毒得泄而阴气恢复,阴毒得泄而阳气恢复,大汗出而病解。《活人书》为何不说是“阳气极盛,阴气极微”为阳毒,“阴气极盛,阳气极微”为阴毒,这样才不至于成为极绝之证。
Chest and hypochondriac pain, deafness, with both the Cun (inch) and Chi (cubit) pulses presenting as Xian (Wiry), indicates a disease of the Shaoyang (Lesser Yang) channel (The discussion can be found in *Huo Ren Shu*, which advocates treating it with Chai Hu Tang).
When pathogenic factors accumulate as excess in the chest, causing郁郁 (depressive) pain in the chest, inability to eat, and relief upon palpation accompanied by salivation and diarrhea occurring more than ten times, while the pulse is paradoxically Chi (Slow) and the Cun pulse is Wei (Fine) and Hua (Slippery), this condition can be treated with emesis; the diarrhea will then cease.
After vomiting or purging, if the patient desires to vomit, experiences chest pain, loose stools, abdominal fullness, and irritability, Tiao Wei Cheng Qi Tang should be used (for details, see the section on Vomiting).
Deafness has two causes: one results from excessive sweating leading to deficiency; the other is due to Shaoyang Wind Strike. Chest and hypochondriac pain, deafness, with both the Cun and Chi pulses presenting as Xian (Wiry), indicates a disease of the Shaoyang channel.
Before taking the pulse, if the patient covers their heart with their hands, and when asked to cough does not do so, this must be because they are deaf and cannot hear the command. This occurs because excessive sweating has caused deficiency (Huang Qi Jian Zhong Tang may be used). In Shaoyang Wind Strike, with bilateral hearing loss, red eyes, chest fullness, and irritability, emesis and purging are contraindicated; if mistakenly used, palpitations and fright will ensue (Xiao Chai Hu Tang may be considered).
Simultaneous disease of the Shaoyang and Jueyin channels presents with deafness, retraction of the testicles, and cold limbs; this is a Liang Gan (Two-Channel) syndrome. When Ying and Wei (Nutritive and Defensive Qi) of the Jueyin channel are blocked, presenting with deafness, testicular retraction, and unconsciousness, the condition is critical. For Shi Wen (Damp-Warmth), treatment focuses on the Taiyin channel; sweating is contraindicated. If sweat is induced, the patient may become unable to speak, suffer from deafness, lose awareness of their condition, develop cyanosis of the body, and change facial color; this is termed "Zhong" (Severe/Heavy) (Bai Hu Jia Cang Zhu Tang may be used).
Yang Du (Yang Toxin) syndrome, at its onset, involves deep and heavy pathogenic toxins. If sweating or purging is missed when indicated, or if heat pathogens enter due to deficiency after vomiting/purging, or if hot medicines are mistakenly taken causing toxic heat to spread like adding firewood to a fire, the symptoms include six pulses being Chen (Deep) and Shi (Excess), tongue rolling and scorching black, nostrils resembling smoke coal, brocade-like erythema on the body and face, delirious speech, running and jumping, climbing walls and roofs, singing while standing high, discarding clothes and running. These are all manifestations. Treatable within five days; untreatable after six or seven days.
Sheng Ma Bie Jia Tang: Treats Yang Du disease characterized by red face with brocade-like macules, sore throat, and expectoration of pus and blood.
Ingredients: Sheng Ma (2 liang), Dang Gui, Shu Jiao (stir-fried to remove moisture), Gan Cao (each 1 liang), Bie Jia (one piece the size of a finger), Xiong Huang (half a liang, ground). The above six ingredients are boiled in four sheng of water to yield one sheng, taken in one dose. Sweating indicates cure. *Zhou Hou Bei Ji Fang* and *Qian Jin Fang* contain Gui Zhi but no Bie Jia in their Yang Du Sheng Ma Tang; Yin Du Gan Cao Tang contains no Xiong Huang.
Appendix:
*Huo Ren Shu* Yang Du Sheng Ma Tang: Treats Shang Han (Cold Damage) becoming Yang Du within one or two days, or transforming into Yang Du after vomiting/purging following medication. Symptoms include backache, irritability, restlessness, red face, delirium, running, hallucinations, diarrhea, floating-large-rapid pulse, red face with brocade-like macules, sore throat, and expectoration of pus and blood. Treatable within five days; untreatable after six or seven days.
Ingredients: Sheng Ma, Xi Jiao (sliced), She Gan, Huang Qin, Ren Shen, Gan Cao (equal parts). The above are coarsely crushed, decocted in water, and taken again after a meal interval. Cover warmly to induce sweating in hands and feet; if unresolved, prepare another dose.
Yang Du Zhi Zi Tang: Treats Yang Du Shang Han with fever and pain in all joints.
Ingredients: Sheng Ma, Huang Qin, Xing Ren, Shi Gao (each 2 qian), Zhi Zi, Chi Shao Yao, Zhi Mu, Da Qing (each 1 qian), Gan Cao (0.5 qian), Chai Hu (1.5 qian). The above are coarsely crushed; take half a liang per dose with five slices of Sheng Jiang and one hundred grains of Chi Xiao Dou, decocted together.
Da Huang San: Treats unresolved Yang Du Shang Han with internal heat, mental confusion, and mania-like state.
Ingredients: Da Huang (1.5 liang), Gui Xin (0.75 liang), Gan Cao (roasted), Mang Xiao, Da Fu Pi, Mu Tong (each 1 liang), Tao Ren (21 pieces). The above are coarsely crushed, decocted in water, and administered until bowel movement is achieved.
Hai Zang's Ge Gen San: Treats Yang Du with body heat like fire, headache, irritability, thirst, dry and painful throat.
Ingredients: Ge Gen (0.75 liang), Huang Qin, Da Huang (vinegar-fried), Gan Cao, Zhi Zi, Po Xiao (each 0.5 liang). The above are coarsely crushed, decocted in water, and taken.
*Huo Ren Shu* Hei Nu Wan: Treats epidemic diseases where no sweat has occurred after six or seven days, with Hong Da (Surging-Large) or Shu (Rapid) pulse, red face, eye pain, severe body heat, irritability, delirium, desire to run, extreme thirst. Also treats cases where heat remains in the chest for over five to six days, jaw is locked preventing speech, classified as Huai Shang Han (Ruined Cold Damage) deemed incurable by physicians, or where vital essence is exhausted but warmth remains in the epigastrium; administering medicine after opening the mouth can revive the patient. Also treats Yang Du and eruptive rashes.
Ingredients: Ma Huang (deprived of nodes, soaked, 3 liang), Da Huang (2 liang), Fu Di Mei (ground), Huang Qin, Mang Xiao, Zao Tu Mo (ground), Liang Shang Chen, Xiao Mai Nu (each 1 liang). The above are powdered, mixed with refined honey to form pills the size of marbles. Grind one pill in fresh well water and administer; if thirsty, allow drinking fresh water freely. Within moments, chills should occur; after chills subside, sweating indicates recovery. If no sweat, administer another pill; mild diarrhea is also effective. "Xiao Mai Nu" refers to immature wheat grains that fail to form ears; when rubbed, they appear black and sprout-like. This medicine is only suitable for patients with extreme thirst and heightened agitation; if not thirsty, administration may cause harm.
For Hong Da pulses, internal and external heat accumulation, rolled and scorched-black tongue, and nostrils resembling smoke coal, apply wet cloths layered and repeatedly soaked in cold water to the chest. Change water dozens of times. For severe heat, immerse the patient in water until heat subsides; this is also a good method.
Dan Sha Wan: Treats critical conditions of Yin and Yang Du in Shang Han.
Ingredients: Bo Shang Liu Huang, Shui Yin, Tai Yin Yuan Jing Shi, Tai Yang Shi (each 1 liang), Xiao Shi (0.5 liang). Powder the above, stir-fry evenly in a non-oiled pot over moderate heat until gray, grind finely. Mix with fresh ginger juice and steamed bread dough to form pills the size of mung beans. Take five pills per dose with Long Nao (Borneol), ginger juice, and honey water to suppress agitation. For Yang Du, use Jujube Decoction; for Yin Du, use plain water. Do not roast under eaves.
Bai Hu Jia Ren Shen Tang is also known as Hua Ban Tang. For severe macules, use Qing Dai Yi Wu Tang. For sore throat, use Xuan Shen Sheng Ma Tang.
Qing Dai Yi Wu Tang:
Ingredient: Qing Dai (size of a jujube). Grind in fresh well water and take.
Xuan Shen Sheng Ma Tang:
Ingredients: Sheng Ma, Xuan Shen, Gan Cao (each 0.5 liang). Decoct three zhan of water to one and a half zhan, strain, and take.
Tao Hua: In Yang Du Shang Han where medication fails, with skin erosion, shedding of hand and foot skin, body red as cinnabar, eyes fiery, extreme irritability and thirst, strong and forceless Hong pulse, and unconsciousness, San Huang Shi Gao Tang is indicated. Alternatively, use Sheng Ma Zhi Zi Tang to induce vomiting. If heat is severe with alternating mania and coma, locked jaw, and inability to swallow medicine, use the water-soaking method; once the jaw relaxes and mania subsides, administering medicine is effective, such as Hei Nu Wan, which should not be used lightly.
Li Gao: When Yang Qi alone prevails and Yin Qi suddenly ceases, irritability, running wildly, delirium, red face, sore throat, and macules occur, or diarrhea of yellow-red stool with Hong Shi or Hua Cu pulses; sour and bitter medicines should be used to rescue. For mild Yin and Yang Du, Jie Geng Da Huang Tang, Yang Du Sheng Ma Tang, Zhi Zi Ren Tang, or Long Dan Cao Yi Wu Tang may be used.
Zhao Sizhen: Yang is rooted in Yin, and Yin is rooted in Yang; without Yang, Yin cannot transform; without Yin, Yang cannot generate. Thus, neither can exist independently. Zhang Zhongjing stated: If Yang Qi ceases first and Yin Qi later, death ensues with blue complexion; if Yin Qi ceases first and Yang Qi depletes later, death ensues with red complexion. This shows that Yin and Yang Qi in the body must not be excessively deficient; once depleted, there is no chance of recovery. However, *Huo Ren Shu* states that Yin Du involves "Yang Qi cessation" and Yang Du involves "Yin Qi cessation." If already ceased, it is an incurable condition, rendering medicine useless. This likely refers to the severity of Yin and Yang syndromes complicated by toxic vapors, hence named Yin Du and Yang Du. Therefore, medicines use Sheng Ma, Xi Jiao, Xiong Huang, Da Qing, etc., to resolve toxicity. Once Yang Du is resolved, Yin Qi recovers; once Yin Du is resolved, Yang Qi recovers, leading to resolution through profuse sweating. Why does *Huo Ren Shu* not describe Yang Du as "extreme Yang abundance and minimal Yin" and Yin Du as "extreme Yin abundance and minimal Yang," thereby avoiding the implication of absolute depletion?