降阴火补肾水。
黄柏（炒褐色） 知母（酒浸，炒，各四两） 熟地（酒蒸） 龟板（酥炙，各六两） 为
末，猪脊髓和蜜丸，桐子大，每服七十丸、空心淡盐汤下。
四者皆滋阴补肾之药。补水即所以降火，壮水之主，以制阳光是也。加脊髓者，
取其能通肾命，以骨入骨，以髓补髓，盖人身肾命，系于脊骨也。此方惟右尺洪大有力者宜之。
此方补精益血，清热润燥，治心肾之圣药。
熟地 生地（俱怀庆者，酒浸，竹刀切片） 山药 茯神（各三两） 龟板（去裙，酥
炙） 山茱萸肉（酒浸，去核） 枸杞子（甘州者，酒洗） 牛膝（各二两） 牡丹皮
鹿茸（火去毛，酥炙，一两） 当归（酒洗） 泽泻 辰砂（一两五钱，为衣） 生甘草（五
钱） 黄柏（一两五钱，盐酒炒褐色） 黄连（酒洗，一两） 为细末，蜜丸，桐子大，
每服五十丸，渐加至一百丸，空心温酒下，或淡盐汤下。
按，年高之人有患其无子者，有恶其白发者，盖无子责乎肾，发白责乎心，何则？
肾主精，精盛则孕成，心主血，血胜则发黑。若嗜欲无穷，而亏其本然之真，忧虑太
过，而损其天然之性。心，君火也，肾，相火也。君火动则相火翕然从之，相火动则天
君亦瞀乱而不宁矣，故发白者，古方皆责之于心，盖以心之所藏者神，神之所附者血，
血之所扰者火也。心火动则血沸腾，血沸腾则神不安，神不安则梦寐纷坛，而髭发渐白
矣。然天地间不过阴阳五行而已，五行有相生者，有相制者，夫心火上炎，由乎肾水亏
乏，不能制耳，是发白不独由于心也。无子者，古方皆责之于肾，盖以肾之所藏者精，
精盈而有子，精亏则乏嗣耳。然肾精之妄泄，由乎心火之所逼，或心肾之气皆虚，不
能摄精所致耳。是无子不独由于肾也。夫心恶热肾恶燥，是方补血生精，宁神降火，清
热润燥，不独施于发白无子二者，其惊悸怔忡，遗精盗汗，目暗耳鸣，腰痛足痿，诸证无不治也。
降伏阴火，滋补肾水。
黄柏（炒至褐色） 知母（用酒浸泡后炒制，各四两） 熟地黄（用酒蒸制） 龟板（用酥油炙烤，各六两） 研为细末，用猪脊髓和蜂蜜制成丸药，大小如梧桐子，每次服用七十丸，空腹时用淡盐水汤送服。
这四味药都是滋阴补肾的药物。补水就是为了降火，这就是“壮水之主，以制阳光”的道理。加入脊髓，是取它通于肾与命门，以骨入骨，以髓补髓，因为人体的肾与命门系连于脊骨。此方仅适用于右尺脉洪大有力的患者。
此方补精益血，清热润燥，是治疗心肾疾病的圣药。
熟地黄 生地黄（均选用怀庆产的，用酒浸泡，用竹刀切片） 山药 茯神（各三两） 龟板（去除裙边，用酥油炙烤） 山茱萸肉（用酒浸泡，去核） 枸杞子（选用甘州产的，用酒清洗） 牛膝（各二两） 牡丹皮 鹿茸（用火燎去毛，用酥油炙烤，一两） 当归（用酒清洗） 泽泻 辰砂（一两五钱，作为丸衣） 生甘草（五钱） 黄柏（一两五钱，用盐和酒炒至褐色） 黄连（用酒清洗，一两） 研为细末，用蜂蜜制成丸药，大小如梧桐子，每次服用五十丸，逐渐增加至一百丸，空腹时用温酒送服，或者用淡盐水汤送服。
按语：年高之人有的患无子之症，有的厌恶白发。无子归责于肾，白发归责于心，为什么呢？肾主藏精，精气旺盛则能受孕成胎；心主藏血，血液充盈则头发乌黑。如果嗜欲无穷，亏损了本然的真气；忧虑太过，损伤了天然的本性。心，是君火；肾，是相火。君火妄动，则相火随之翕然而起；相火妄动，则天君（心神）也会昏乱而不安宁。所以，白发古方都归责于心，因为心所藏的是神，神依附于血，扰乱神的因素是火。心火妄动则血液沸腾，血液沸腾则神不安宁，神不安宁则梦境纷繁，胡须和头发渐渐变白。然而天地间不过是阴阳五行罢了，五行中有相生者，也有相制者。心火上炎，是由于肾水亏乏，不能制约所致，因此白发不独由心引起。无子者，古方都归责于肾，因为肾所藏的是精，精气充盈则有子嗣，精气亏虚则缺乏后代。然而肾精的妄泄，是由于心火的逼迫，或者是心肾之气皆虚，不能摄持精液所致。因此，无子不独由肾引起。心厌恶热，肾厌恶燥，此方能补血生精，宁心安神，降伏火热，清热润燥，不仅适用于白发和无子这两种情况，对于惊悸怔忡、遗精盗汗、目暗耳鸣、腰痛足痿等诸证，无不治疗。
To subdue Yin fire and tonify Kidney water.
Huangbai (Phellodendri Cortex, stir-fried until brown) Zhimu (Anemarrhenae Rhizoma, soaked in wine and stir-fried, each 4 liang) Shudi (Rehmanniae Radix Praeparata, steamed with wine) Guiban (Testudinis et Carapacis et Plastrum, roasted with suet, each 6 liang) Ground into fine powder, mixed with pig spinal cord and honey to make pills, size of Sophora japonica seeds. Take 70 pills per dose, on an empty stomach, washed down with light salt water decoction.
These four herbs are all medicines for nourishing Yin and tonifying the Kidney. Nourishing water is the way to subdue fire; this is the principle of "strengthening the master of water to control the sunlight" (Zhuangshui zhizhu, yi zhi yangguang). The addition of spinal cord is to utilize its ability to connect with the Kidney and Mingmen, entering bone with bone and replenishing marrow with marrow, as the human body's Kidney and Mingmen are connected to the spinal column. This formula is suitable only for those whose Right Chi pulse is surging, large, and forceful.
This formula tonifies essence and blood, clears heat and moistens dryness, and is a sacred medicine for treating Heart-Kidney disorders.
Shudi (Prepared Rehmannia Root) Shengdi (Raw Rehmannia Root, both from Huaiqing, soaked in wine, sliced with a bamboo knife) Shanyao (Dioscoreae Rhizoma) Fushen (Poria with Hostwood, each 3 liang) Guiban (Testudinis et Carapacis et Plastrum, skirt removed, roasted with suet) Shanzhuyu (Corni Fructus, soaked in wine, pitted) Gouqizi (Lycii Fructus, from Ganzhou, washed with wine) Niuxi (Achyranthis Bidentatae Radix, each 2 liang) Mudanpi (Moutan Cortex) Lurong (Cervi Cornu Degelatinatum, fire-burned to remove hair, roasted with suet, 1 liang) Danggui (Angelicae Sinensis Radix, washed with wine) Zexie (Alismatis Rhizoma) Chensha (Cinnabaris, 1.5 liang, used as coating) Shenggancao (Glycyrrhizae Radix et Rhizoma Recens, 5 qian) Huangbai (Phellodendri Cortex, 1.5 liang, stir-fried with salt and wine until brown) Huanglian (Coptidis Rhizoma, washed with wine, 1 liang) Ground into fine powder, made into pills with honey, size of Sophora japonica seeds. Take 50 pills per dose, gradually increasing to 100 pills, on an empty stomach, washed down with warm wine or light salt water decoction.
Note: Elderly people may suffer from infertility or dislike white hair. Infertility is attributed to the Kidney, and white hair to the Heart. Why? The Kidney governs Essence; when Essence is abundant, conception occurs. The Heart governs Blood; when Blood is sufficient, hair remains black. If desires are endless, depleting the original true Qi; if worries are excessive, damaging the natural nature. The Heart is the Minister Fire (Junhuo); the Kidney is the Official Fire (Xianghuo). When Minister Fire moves, Official Fire rises accordingly; when Official Fire moves, the Heavenly Ruler (Shen/Spirit) becomes confused and restless. Therefore, ancient formulas attribute white hair to the Heart, because the Heart stores Spirit, Spirit attaches to Blood, and Fire disturbs Blood. When Heart Fire moves, Blood boils; when Blood boils, Spirit is unsettled; when Spirit is unsettled, dreams become chaotic, and beard and hair gradually turn white. However, within heaven and earth, there are only Yin and Yang and the Five Elements. Among the Five Elements, there are generating relationships and controlling relationships. Heart Fire flaming upward is due to the deficiency of Kidney Water, which fails to control it; thus, white hair is not solely caused by the Heart. Infertility is attributed to the Kidney in ancient formulas, because the Kidney stores Essence; when Essence is full, there are offspring; when Essence is deficient, there is no heir. However, the reckless loss of Kidney Essence is caused by the pressure of Heart Fire, or by the deficiency of Qi in both Heart and Kidney, failing to secure Essence. Thus, infertility is not solely caused by the Kidney. The Heart dislikes heat, and the Kidney dislikes dryness. This formula nourishes Blood and generates Essence, calms the Spirit and subdues Fire, clears heat and moistens dryness. It is applicable not only to white hair and infertility but also to palpitations, nocturnal emission and night sweats, dim vision and tinnitus, lower back pain and weak legs; it treats all these syndromes.