〔世〕憎寒困倦，或发寒战，能令痘子缩伏，宜用陈文中异功散。（方见痘出不快条。）
〔钱〕寒战切牙黑陷者，百祥丸下之。（方见黑靥条。）尝治痘疮寒战，用白术、 、归加芩治之，愈。
〔丹〕胡宅痘疮发热，此血少有余毒也。
陈皮 白术 归身 白芍药（各三钱） 牛蒡子（研破，炒，二钱） 木通 犀角 生甘节 川芎（各一
钱半）
分六帖，水盏半，煎。食前稍热，服。
〔《活》〕连翘散 治一切热，兼治疮疹如神。
连翘 防风 栀子 甘草（各等分）
上为末，水煎服。（海藏云∶治热在外而不厥，此少阳药也。）
易老云∶凉膈去大黄、芒硝者，能解六经中热。此不惟解热，治小儿 疹热候，亦使发之。则本药
与防风、荆芥二物各半，白水煎服。
〔河〕栀子金花丸
黄芩 黄连 黄柏 山栀（炒。各等分）
上末，滴水丸如豆子大，每服五丸，白汤下。
〔钱〕三黄丸 治诸热。
黄芩（半两） 大黄（煨） 黄连（各二钱半）
上为细末，糊丸绿豆大。每服五七丸至十五、二十丸，食后米饮送下。
上钱氏云∶有小热者解毒。海藏谓解毒者，三黄丸、金花丸之类是也。
四圣散（方见出不快。） 海藏紫草木通汤（方见同上。） 导赤散（方见治虚实。） 八正散（方见淋部。）
〔丹〕有初起烦躁谵语，狂渴引饮，若饮水则后来靥不齐，急以凉药解其标，如益元散之类可用。
上五方，利小便退热之剂。钱氏云∶有大热者利小便。又云∶身热烦渴，腹满而喘，大小便涩，面
赤闷乱，大吐，此当利小便，盖此用导赤散之类是也。
〔钱〕宣风散
槟榔（两个） 陈皮 甘草（各半两） 牵牛（四两，生半熟半）
上为细末，三二岁蜜汤调下五分，以上一钱，食前。易老加防风。
〔云〕通膈丸 利上下气血药也。
大黄 牵牛 木通（各等分）
上为细末，滴水丸如粟粒大。每服三五十丸，量儿大小虚实加减。
上钱氏云∶有大热，利小便，不瘥者，宜宣风下之。
〔子和〕蔡河有舟师，偶见败蒲一束，沿流而下。渐泊舟次，似闻啼声而微，开视之，惊见一儿，
四五岁许，疮 周匝，密不容隙，两目皎然，饥而索食，因以粥食之。其妻怒曰∶自家儿女多，惹疮
传染奈何？私料蔡河流缓，必不远，持儿一鞋逆流而上，遍问皆曰无此儿。行二十里，又至一村落。
舟师呼于市曰∶有儿年状如许疮 ，死弃河中，今复活。忽酒邸中有人出，曰∶我某村某人也，儿四
五岁，死于疮 。舟师出其鞋，其人泣曰∶是吾儿也。奔往视，惊见儿活，流涕拜谢舟师，抱儿归，
今二十余矣。此儿本死，得水而生，第未谂其疮 之疾，寒耶热耶。
【世】（王隐君）患者憎恶寒冷、困倦乏力，或者出现寒战，这会导致痘疹内缩伏陷，适宜使用陈文中的异功散。（方剂见“痘出不快”条。）
【钱】（钱乙）若寒战剧烈且伴有咬牙、痘色黑陷者，应用百祥丸攻下。（方剂见“黑靥”条。）我曾治疗痘疮寒战，使用白术、当归、黄芩等药进行治疗，痊愈。
【丹】（朱丹溪）胡家患痘疮发热，这是血虚兼有余毒所致。
陈皮 白术 当归身 白芍药（各三钱） 牛蒡子（研碎，炒，二钱） 木通 犀角 生甘草节 川芎（各一钱半）
分为六帖，用水一盏半煎煮。在饭前稍温热后服用。
【《活》】（《活幼心书》）连翘散 治疗各种热证，兼治疮疹效果神奇。
连翘 防风 栀子 甘草（各等分）
以上药物研为细末，水煎服用。（海藏云：治疗热邪在表而未发生厥逆的，这是少阳经的药物。）
易老云：凉膈散去大黄、芒硝的，能解除六经中的热邪。这不仅能够清热，治疗小儿出疹时的热候，也能促使疹毒发出。则原药与防风、荆芥两味药各取一半，用白水煎服。
【河】（张元素）栀子金花丸
黄芩 黄连 黄柏 山栀（炒。各等分）
以上药物研为细末，滴水泛丸如豆粒大，每次服用五丸，白开水送下。
【钱】（钱乙）三黄丸 治疗各种热证。
黄芩（半两） 大黄（煨制） 黄连（各二钱半）
以上药物研为细末，用糊剂制成绿豆大的丸药。每次服用五至七丸，或十五、二十丸，饭后用米汤送下。
上述钱氏云：有轻微热邪的应解毒。海藏认为解毒的药，是三黄丸、金花丸之类的。
四圣散（方剂见“出不快”。） 海藏紫草木通汤（方剂见同上。） 导赤散（方剂见“治虚实”。） 八正散（方剂见“淋部”。）
【丹】（朱丹溪）痘疮初起时出现烦躁、说胡话、极度口渴想喝水，如果饮水则后来痘疹收靥不齐，急需以凉性药物解除其标症，如益元散之类可以使用。
上述五个方剂，都是通利小便以退热的药剂。钱氏云：有大热邪的应通利小便。又说：身体发热、烦渴、腹部胀满而气喘、大小便涩滞、面色红赤、胸闷烦乱、剧烈呕吐，这应当通利小便，大概这里使用导赤散之类的就是此意。
【钱】（钱乙）宣风散
槟榔（两个） 陈皮 甘草（各半两） 牵牛（四两，生用和熟用各半）
以上药物研为细末，二三岁儿童用蜜汤调服五分，以上年龄服一钱，饭前服用。易老加防风。
【云】（云岐子）通膈丸 是疏通上下气血的药物。
大黄 牵牛 木通（各等分）
以上药物研为细末，滴水泛丸如粟米粒大。每次服用三五十丸，根据患儿大小虚实加减用量。
上述钱氏云：有大热邪，通利小便后未痊愈的，适宜用宣风散攻下。
【子和】（张从正）蔡河流有一位船夫，偶然看见一束败蒲，顺流而下。渐渐将船停靠在岸边，似乎听到微弱的啼哭声，打开查看，惊讶地发现一个婴儿，大约四五岁，周身布满疮疹，密密麻麻没有缝隙，但两眼明亮有神，饥饿地索要食物，于是给他粥吃。他的妻子愤怒地说：“自己儿女多，惹上疮疹传染怎么办？”私下推测蔡河水势缓慢，一定不远，拿着孩子的一只鞋逆流而上，到处询问都说没见过这孩子。走了二十里，又到了一个村落。船夫在集市上呼喊：“有个孩子年纪如此，长满疮疹，被丢弃河中，现在复活了。”忽然酒肆中有人出来，说：“我是某村某人，我的孩子四五岁，死于疮疹。”船夫拿出那只鞋，那人哭着说：“这是我的儿子。”飞奔前去查看，惊讶地发现孩子活着，流泪拜谢船夫，抱着孩子回家，如今已经二十多岁了。这个孩子本来已死，因得水而存活，只是不清楚他患的是什么疮疹疾病，是寒证还是热证。
[Shi] (Wang Yinjun) The patient experiences aversion to cold, fatigue and lassitude, or shivering chills. This condition may cause the smallpox lesions to retract and subside internally. It is appropriate to use Chen Zhongwen's Yigong San (Isolated Efficacy Powder). (Formula see "Smallpox eruption slow" section.)
[Qian] (Qian Yi) If shivering chills are severe accompanied by teeth grinding and black depression of the lesions, Baixiang Wan (Hundred Miracles Pill) should be used to purge. (Formula see "Black crusts" section.) I once treated smallpox with shivering chills using Baizhu (Atractylodis Rhizoma), Danggui (Angelicae Sinensis Radix), Huangqin (Scutellariae Radix), etc., and achieved a cure.
[Dan] (Zhu Danxi) Hu family's smallpox fever is due to blood deficiency with residual pathogenic heat/toxin.
Chenpi (Citri Reticulatae Pericarpium), Baizhu (Atractylodis Rhizoma), Dangguishen (Angelicae Sinensis Radix), Baishaoyao (Paeoniae Radix Alba) (each 3 qian), Niubangzi (Arctii Fructus, crushed, stir-fried, 2 qian), Mutong (Akebiae Caulis), Xijiao (Rhinocerotis Cornu), Sheng Ganjiejie (Glycyrrhizae Radix et Rhizoma raw with nodes), Chuanxiong (Ligustici Chuanxiong Rhizoma) (each 1.5 qian).
Divide into six doses. Decoct with one and a half bowls of water. Take slightly warm before meals.
[Huo] (from *Huoyou Xinshu*) Lianqiao San (Forsythia Powder) treats all types of heat; it also treats sores and rashes with miraculous effect.
Lianqiao (Forsythiae Fructus), Fangfeng (Saposhnikoviae Radix), Zhizi (Gardeniae Fructus), Gancao (Glycyrrhizae Radix et Rhizoma) (equal parts).
Grind the above into fine powder, decoct with water and take orally. (Haizang said: Treats heat located in the exterior without jue-ni [cold extremities]; this is a Shaoyang meridian formula.)
Yilao said: Liangge San (Cool the Diaphragm Powder) without Dahuang (Rhei Radix et Rhizoma) and Mangxiao (Natrii Sulfas) can resolve heat in the six meridians. This not only clears heat but also treats pediatric exanthematous heat conditions, promoting eruption. Use half the original formula mixed with half Fangfeng (Saposhnikoviae Radix) and Jingjie (Schizonepetae Spica), decocted in plain water.
[He] (Zhang Yuansu) Zhizi Jinhua Wan (Gardenia Golden Flower Pill)
Huangqin (Scutellariae Radix), Huanglian (Coptidis Rhizoma), Huangbai (Phellodendri Cortex), Shan Zhi (Gardeniae Fructus, stir-fried) (equal parts).
Grind into fine powder, make pills with water drops, size of beans. Take five pills per dose, washed down with warm water.
[Qian] (Qian Yi) Sanhuang Wan (Three Yellows Pill) treats various heat syndromes.
Huangqin (Scutellariae Radix, 0.5 liang), Dahuang (Rhei Radix et Rhizoma, baked), Huanglian (Coptidis Rhizoma) (each 2.5 qian).
Grind into fine powder, make pills with paste, size of mung beans. Take five to seven pills, or fifteen to twenty pills per dose, after meals with rice drink.
Regarding Qian's statements above: For mild heat, use detoxification. Haizang considers that detoxifying agents include Sanhuang Wan (Three Yellows Pill) and Jinhua Wan (Golden Flower Pill).
Sisheng San (Four Saints Powder) (Formula see "Eruption slow"). Haizang Zicao Mutong Tang (Purple Coral and Akebia Decoction) (Formula see same). Daochi San (Directing Red Powder) (Formula see "Treating deficiency/excess"). Bazheng San (Eight Upright Powder) (Formula see "Strangury section").
[Dan] (Zhu Danxi) At the initial stage, if there is irritability, delirious speech, mania, extreme thirst and desire to drink, drinking water will later result in uneven crusting of the lesions. Urgently use cooling herbs to resolve the branch symptoms, such as Yiyuan San (Benefit Origin Powder).
The above five formulas are diuretic agents to reduce fever. Qian said: For severe heat, promote urination. He also said: Body heat, irritability and thirst, abdominal fullness with panting, difficult urination and defecation, red face, chest oppression and confusion, severe vomiting—these indicate the need to promote urination. Using Daochi San (Directing Red Powder) here exemplifies this principle.
[Qian] (Qian Yi) Xuanfeng San (Dispersing Wind Powder)
Binglang (Arecae Semen, two pieces), Chenpi (Citri Reticulatae Pericarpium), Gancao (Glycyrrhizae Radix et Rhizoma) (each 0.5 liang), Qianniu (Pharbitidis Semen, four liang, half raw half cooked).
Grind into fine powder. For children aged two or three, mix with honey water and take 0.5 qian; for older children, take 1 qian. Take before meals. Yilao adds Fangfeng (Saposhnikoviae Radix).
[Yun] (Yun Qizi) Tongge Wan (Unblocking Diaphragm Pill) is an herb to unblock qi and blood in the upper and lower jiao.
Dahuang (Rhei Radix et Rhizoma), Qianniu (Pharbitidis Semen), Mutong (Akebiae Caulis) (equal parts).
Grind into fine powder, make pills with water drops, size of millet grains. Take thirty to fifty pills per dose, adjusting according to the child's age and deficiency/excess status.
Regarding Qian's statement above: For severe heat, if promoting urination does not improve the condition, it is suitable to use Xuanfeng San (Dispersing Wind Powder) to purge.
[Zihe] (Zhang Congzheng) Cai Heliu had a boatman who accidentally saw a bundle of decaying cattail reeds floating downstream. As he moored the boat near the bank, he seemed to hear faint crying. Upon opening and inspecting, he was surprised to find a child, about four or five years old, covered entirely in dense sores/rash with no space between them, yet his eyes were bright and clear. The child was hungry and asking for food, so the boatman fed him porridge. The child's wife was angry, saying, "We have many children of our own; how can we risk catching this sore disease?" She privately reasoned that since the Cai River current was slow, the child must not be far. Holding one of the child's shoes, she went upstream against the current, asking everywhere, but no one had seen such a child. After walking twenty li, she reached another village. The boatman shouted in the market, "A child of this age, covered in sores, was thrown into the river and has now revived." Suddenly, someone came out from a tavern and said, "I am so-and-so from such-and-such village. My child, aged four or five, died of sores." The boatman showed the shoe, and the man cried, "This is my son!" He rushed to check, was shocked to see the child alive, shed tears, bowed in gratitude to the boatman, and took the child home. The child is now over twenty years old. This child was originally dead but lived because of water. However, it is unknown what specific sore/rash disease he suffered from, whether it was a cold syndrome or a heat syndrome.