《病源论》云∶皲裂者，肌肉破也。言冬时触冒风寒，手足破，故谓之皲裂也。
《葛氏方》治冬天手足皲裂血出及瘃冻方∶
取麦苗煮令浓热的的尔，以洗渍之。
《千金方》治手足皴劈破裂血出疼痛方∶
猪脂着热酒以洗之，即瘥。
《集验方》手足瘃坏方∶
蜀椒四合。以水一斗，煮三沸，去滓，以洗渍之。
《苏敬本草经》注∶嚼白芨，以填之，效。
《范汪方》∶取葱叶萎黄叶，煮以渍，洗之良。
《新录方》∶咋蒜封之。
又方∶车 脂涂之。
《病源论》云∶人手足忽然皮浓涩而圆强如茧者，谓之胼（步田反）胝。此由血气沉行，
不荣
《葛氏方》手足忽发胝方∶
取粢米粉，铁枪熬令赤，以众人唾和之以涂上，浓一寸，即消。（《范汪方》同之。）
玉箸葙方∶以盐涂胝上，令牛舐之不过三。
又方∶作艾炷灸其上三壮。
《新录方》∶以温尿渍，瘥。
《病源论》云∶逆胪者，手足爪甲际皮剥起，谓之逆胪。风邪入于腠理，血气不和故也。
《千金方》手足逆胪方∶
亚青珠（一分） 干姜（二分）
捣，以粉疮上，日三。〔今按（一本无）∶《葛氏方》是名琅 者，非真珠，亦以猪脂和
涂之
《枕中方》治人手足粗理方∶
取榆树孔中水洗，即细如指。
《诸病源候论》说：皲裂，是指肌肉皮肤破裂。说的是冬天接触冒犯了风寒，导致手足皮肤破裂，所以称为皲裂。
《葛氏方》治疗冬天手足皲裂出血及冻疮的方子：
取麦苗煮成浓热的药液，用来清洗浸泡患处。
《千金方》治疗手足皮肤粗糙开裂、破裂出血疼痛的方子：
用猪脂混合热酒来清洗患处，立刻就能痊愈。
《集验方》治疗手足冻疮坏死的方子：
蜀椒四合。用水一斗，煮开三次，去掉药渣，用来清洗浸泡患处。
《苏敬本草经》注解说：嚼碎白芨（Bletilla striata, 白及），填塞在伤口处，有效。
《范汪方》：取葱叶中枯萎发黄的叶子，煮水后浸泡清洗，效果很好。
《诸病源候论》说：人的手足突然皮肤变得浓厚涩滞且坚硬如茧一样的，称为胼胝（pián zhī，老茧）。这是由于气血运行沉滞，不能滋养肌肤所致。
《葛氏方》治疗手足突然长出老茧的方子：
取粢米粉（小米粉），用铁锅炒至发红，用众人的唾液调和后涂在上面，厚度约一寸，老茧就会消退。（《范汪方》与此相同。）
《新录方》：用温尿液浸泡，痊愈。
《诸病源候论》说：逆胪（nì lú，指甲周围倒刺或皮肉翘起），是指手足指甲边缘的皮肤剥起，称为逆胪。这是风邪侵入腠理，导致气血不和的缘故。
《千金方》治疗手足逆胪的方子：
亚青珠（一分） 干姜（二分）
捣碎，将药粉撒在疮口上，每天三次。〔今按（另一版本没有）：《葛氏方》所说的“琅玕”不是真珠，也用猪脂调和后涂抹。
The *Zhubing Yuanhou Lun* (Treatise on the Pathogenesis and Manifestations of All Diseases) states: "Gunchlie" (skin fissure/crack) refers to the rupture of muscle tissue. It is named so because exposure to wind-cold during winter causes the skin of the hands and feet to crack.
The *Ge Shi Fang* (Prescriptions by Ge Hong) for treating winter hand and foot fissures with bleeding and frostbite:
Take wheat seedlings, boil them until the decoction is thick and hot, and use it to wash and soak the affected area.
The *Qianjin Fang* (Essential Prescriptions Worth a Thousand Gold) for treating rough, cracked, bleeding, and painful hands and feet:
Apply pig fat mixed with hot wine to wash the affected area; this will lead to immediate recovery.
The *Jiyan Fang* (Collected Proven Prescriptions) for treating necrotic frostbite of hands and feet:
Take four he of Sichuan pepper (Shu Jiao). Boil in one dou of water for three boils, remove the dregs, and use the liquid to wash and soak the affected area.
Annotations in *Su Jing's Bencao Jing* (Compendium of Materia Medica by Su Jing): Chewing Bletilla striata (Baiji, White Cohort Lily Rhizome) and packing it into the wound is effective.
The *Fan Wang Fang*: Take withered, yellowing scallion leaves, boil them in water to soak and wash; this is beneficial.
The *Xinlu Fang*: Crush garlic and apply it as a poultice.
Another prescription: Apply char fat (Che Zhi) to the affected area.
The *Zhubing Yuanhou Lun* states: When the skin of the hands and feet suddenly becomes thick, rough, and hard like a callus, it is called Piandi (callus/corn). This occurs due to stagnant blood and qi circulation failing to nourish the skin.
The *Ge Shi Fang* for sudden onset of calluses on hands and feet:
Take millet flour (Zimi Fen), stir-fry it in an iron pan until red-hot, mix it with saliva from multiple people, apply it thickly (about one cun), and the callus will disappear. (This is identical to the *Fan Wang Fang*.)
Yuzhu Xiang Prescription: Apply salt to the callus and let a cow lick it; this should be done no more than three times.
Another prescription: Make moxa cones and apply three moxibustion treatments (Zhuang) on top of the callus.
The *Xinlu Fang*: Soak in warm urine for recovery.
The *Zhubing Yuanhou Lun* states: "Nili" (hangnail/peeling skin around nails) refers to the peeling and lifting of skin at the margins of the fingernails or toenails. This is caused by wind-pathogen invading the couli (pores/skin interstices) and disharmony of blood and qi.
The *Qianjin Fang* for treating hangnails on hands and feet:
Ya Qing Zhu (one fen) and Dried Ginger (Gan Jiang, two fen).
Pound into powder, sprinkle onto the lesion three times daily. [Note: Another version states that what the *Ge Shi Fang* calls "Langgan" is not true pearl, but can also be mixed with pig fat for topical application.]
The *Zhenzhong Fang* for treating rough-textured hands and feet:
Wash with water collected from holes in elm trees; the skin will become fine and smooth like fingers.