香薷（二两） 白扁豆 浓朴（姜汁炒） 茯神（各一两） 炙甘草（半两）
疟发时，独热无寒者，名曰瘅疟，当责之暑，宜此方主之。
暑，阳邪也。《内经》曰∶脉虚身热，得之伤暑，又曰∶因于暑，汗，烦则喘喝，静则
多言，体若燔炭。故独热无寒之疟，责其因于暑也。香薷味薄而气清，能解表里之暑；扁豆
味甘而性平，能解肠胃之暑；浓朴苦辛，破暑饮也；甘草性平，解暑毒也。《易》曰∶火就
燥，则暑邪中人，先就于心，茯神之用，乃所以宁心耳。或问风亦阳邪也，瘅疟何以不责之
风？余曰∶风为少阳，又为厥阴，在六气犹未纯阳，若临证主方处治，辛热固不可用，如辛
凉发散之剂，用之未为不可。此在医者潜心，初不必泥于一方也。
附子（一枚，盐水煮，去皮脐） 大枣（七枚）
疟发时，独寒无热，脉迟者，名曰牝疟，当责之寒，宜此方主之。
牝，阴也。王冰曰∶益火之原，以消阴翳。故独寒无热之疟，用附子之辛以主之，佐以
大枣七枚，取其能和附热，且引之入至阴耳。
蜀漆（烧去腥） 云母（烧二日夜） 龙骨（ ，各等分）
共为末，于未发前浆水服下半钱。
此仲景治牝疟之方也，病原于顽痰 瘕者，此方主之。
牝，阴也，无阳之名。顽痰乃至阴所化， 瘕乃凝结之阴，故令人有寒无热。蜀漆、云
母、龙骨，既经烧炼，则味涩而辛热，味涩可以固既脱之阳，辛热可以消固结之阴。仲景治
火劫亡阳之证，于桂枝汤去芍药加蜀漆、龙骨辈，名曰救逆汤，是二物之为纯阳可知。云母
烧二日夜，则寒性亦去而纯阳矣，宜仲景之用之也。
香薷（二两） 白扁豆 浓朴（用姜汁炒制） 茯神（各一两） 炙甘草（半两）
疟疾发作时，只有发热而没有恶寒的，称为瘅疟（一种以但热不寒为特征的疟疾），应当归因于暑邪，适宜用此方主治。
暑，属于阳邪。《内经》说：脉象虚而身体发热，是由于伤暑所致；又说：感受暑邪，出汗，心烦则气喘呼叫，安静时则多言乱语，身体像燃烧的炭火一样烫。所以只有发热没有恶寒的疟疾，归咎于因暑邪引起。香薷气味轻薄而清纯，能解除表里之暑邪；扁豆味甘且性平，能解除肠胃之暑邪；浓朴味苦辛，能破除暑湿停饮；甘草性平，能解暑毒。《易经》说：火趋向干燥之物，那么暑邪侵入人体，首先就会影响心脏，使用茯神的用意，正是为了宁心安神。有人问：风也是阳邪，为什么瘅疟不归咎于风？我说：风对应少阳经和厥阴经，在六气中还不算纯粹的阳邪，如果在临证处方治疗时，辛热的药物固然不可用，但如辛凉发散的药剂，使用它并非不可以。这在于医生潜心研究，起初不必拘泥于某一个固定的方子。
疟疾发作时，只有寒冷而没有发热，脉象迟缓的，称为牝疟（一种以但寒不热为特征的疟疾），应当归因于寒邪，适宜用此方主治。
牝，属阴。王冰说：补益火的源头，以消除阴寒的遮蔽。所以只有寒冷没有发热的疟疾，用附子的辛热来主治，佐以大枣七枚，取它能调和附子的燥热，并且引导药力进入至阴之处。
共同研成细末，在疟疾发作前，用浆水送服半钱。
这是张仲景治疗牝疟的方子，病因是顽痰和癥瘕（指腹内结块的病证）的，此方主治。
牝，属阴，没有阳的名称。顽痰是由至阴所化生，癥瘕是凝结的阴邪，所以使人只感到寒冷而不发热。蜀漆、云母、龙骨，经过烧炼之后，味道涩而性辛热，味涩可以固摄已经脱失的阳气，辛热可以消散固结的阴邪。张仲景治疗因火疗劫夺导致亡阳的证候，在桂枝汤中去掉芍药加上蜀漆、龙骨之类，名叫救逆汤，由此可知这两味药是纯阳之品。云母烧制两个夜晚，其寒性也就去除了而变为纯阳，适宜张仲景使用它。
Xiangru (Two Liang) Bai Biandou (Coix Seed, *Coicis Semen*) Nongpu (Stir-fried with Ginger Juice, *Magnoliae Officinalis Cortex*) Fushen (One Liang each, *Poria with Hostwood*) Zhi Gancao (Half Liang, Honey-fried Licorice Root, *Glycyrrhizae Radix et Rhizoma Preparata*)
When malaria attacks, characterized by fever alone without chills, it is named Dan Malaria (Malaria with only heat and no cold). This should be attributed to Summerheat (*Shu*), and this formula is suitable for its treatment.
Summerheat is a Yang pathogenic factor. The *Neijing* states: "A deficient pulse and body heat result from injury by summerheat." It also states: "Affected by summerheat, there is sweating; if vexed, there is panting and shouting; if quiet, there is excessive talking; the body feels like burning charcoal." Therefore, malaria with only heat and no cold is attributed to the influence of summerheat. Xiangru has a light taste and clear aroma, capable of resolving summerheat in both the exterior and interior; Biandou has a sweet taste and neutral nature, capable of resolving summerheat in the intestines and stomach; Nongpu is bitter and acrid, capable of breaking up summerheat-dampness retention; Gancao has a neutral nature and resolves summerheat toxicity. The *Yijing* says: "Fire tends toward dryness." Thus, when summerheat pathogen invades the human body, it first affects the Heart. The use of Fushen is intended to calm the Heart and spirit. One might ask: Wind is also a Yang pathogen; why is Dan Malaria not attributed to Wind? I reply: Wind corresponds to Shaoyang and Jueyin, and in the Six Qi, it is not purely Yang. In clinical practice and prescription, acrid-hot drugs are certainly contraindicated, but acrid-cool dispersing agents may be used appropriately. This depends on the physician's profound study; one need not rigidly adhere to a single formula.
Fuzi (One Pill, boiled in salt water, skin and umbilicus removed) Dazao (Seven Dates, *Ziziphi Jujubae Fructus*)
When malaria attacks, characterized by cold alone without fever and a slow pulse, it is named Pin Malaria (Malaria with only cold and no heat). This should be attributed to Cold (*Han*), and this formula is suitable for its treatment.
"Pin" denotes Yin. Wang Bing stated: "Replenish the source of Fire to eliminate the shadows of Yin." Therefore, for malaria with only cold and no heat, the acridity of Fuzi is used as the principal agent, assisted by seven Dazao, to harmonize the heat of Fuzi and guide it into the deepest Yin.
Shuqi (Burned to remove fishy odor) Yunmu (Burned for two days and nights) Longgu (Equal parts, *Fossil Bones*)
Grind all together into powder. Take half a Qian before the onset of the attack, administered with Jiangshui (fermented grain water).
This is Zhang Zhongjing's formula for treating Pin Malaria. It is indicated for etiologies involving stubborn phlegm (*Wan Tan*) and mass formations (*Zhijia*).
"Pin" denotes Yin, lacking the name of Yang. Stubborn phlegm is transformed from extreme Yin, and *Zhijia* represents condensed Yin pathogen; thus, they cause cold without heat. Shuqi, Yunmu, and Longgu, after being calcined, become astringent and acrid-hot. The astringency can secure yang that has already escaped, and the acrid-heat can dissolve consolidated yin. When Zhang Zhongjing treated conditions of Yang collapse caused by fire therapy劫夺 (coercion), he modified Guizhi Tang by removing Shaoyao and adding Shuqi and Longgu, naming it Jiuni Tang (Rescue the Perdition Decoction). This demonstrates that these substances are purely Yang. Yunmu burned for two days and nights loses its cold nature and becomes purely Yang, making it suitable for Zhang Zhongjing's use.