治冷劳气血枯竭，肉瘠齿落，肢倦言微吴鹤皋曰∶凡人之身有真火焉，寄于右肾，行于
三焦，出入于甲胆，听命于天君，所以温百骸、养脏腑、充九窍者，皆此火也，为万物之父
，故曰天非此火不能生物，人非此火不能有生，此火一息，犹万物无父，故其肉衰而瘠，血
衰而枯，骨衰而齿落，筋衰而肢倦，气衰而言微矣。
石硫黄（一斤） 猪大肠（二尺。）将硫黄为末，实猪肠中，烂煮三时，取出去肠，蒸
饼为丸，如梧子大。每服十丸，日渐加之（凡服硫黄者，忌食诸禽兽血。）
此足少阴命门药也。硫黄，火之精也，亦号将军（大黄至寒，亦号将军，）故用之以补
火；以其大热有毒，故用猪肠烂煮以解之；庸俗之人，忌而罕用，盖不知有破邪归正、返滞
还清、消阴回阳、化魄生魂之力也（吴鹤皋曰∶戴元礼有言曰，诸凉药皆滞，诸热药皆燥，
惟硫黄热而不燥。昔仁和吏早衰，服之年至九十。他如范文正公之金液丹，《得效》之玉真
丸，《和剂》之来复丹、半硫丸、灵砂丹，《百选》之二气丹，《活人》之返阴丹，杨氏之紫
霞丹皆用之，但所主各有攸当耳。昂按∶人有真阳虚衰，附桂所不能补者，非硫黄不能补之；
今人以为燥毒，弃而不用，不知硫黄性虽燥而疏利，与燥涩者不同，本草称为救危妙药，道
家以之服食，尊之为金液丹，固人所可常服者；且硝与磺，一阴一阳，然皆同类之物，今人
惟知用芒
附∶金液丹∶硫黄（十两）。研末，瓷盆盛。水和赤石脂封口，盐泥固济，日干；地内
埋一小罐，盛水令满，安盆在内，用泥固济。慢火养七日七夜，加顶火一斤 ，取出，研末，
蒸饼丸
玉真丸∶生硫黄（二两） 生硝石 石膏 半夏（一两）。姜汁糊丸。姜汤或米饮下，
每四十丸
来复丹∶太阴元精石 舶上硫黄 硝石（一两，硝黄同微炒，不可火大，柳条搅结成砂
子） 五灵脂（去砂石） 青皮 陈皮（一两。）醋糊丸。米饮下。治伏暑泄泻，身热脉弱
（《玉机微义》曰∶硝石性寒，佐以陈皮，其性疏快，硫黄能利人，若作暖药止泻，误矣。
此由啖食生冷，或冒暑热，中脘闭结，挥霍变乱，此药通利三焦，分理阴阳，服之甚验。若
因暑火湿热者勿用。
半硫丸∶半夏 硫黄，等分。生姜糊丸。治老人虚秘、冷秘。
灵砂丹∶水银三两 硫黄（一两。）炼成研末，糯米糊丸。治诸虚痼冷。
二气丹∶硝石 硫黄，等分。为末。石器炒成砂，再研，糯米糊丸，梧子大。每服四十
丸，井水下。治伏暑伤冷，二气交错，中脘痞结，或呕或泄，霍乱厥逆。
返阴丹∶治阴毒伤寒，心神烦躁，四肢逆冷。硫黄五两 硝石 太阴元精石一两 附子
（炮） 干姜（炮） 桂心（五钱）。用铁铫先铺元精末一半，次铺硝石末一半，中间下硫
黄末，又着硝石一半盖硫黄，再以元精末盖上。用小盏合著炭三斤，烧令得所，勿令烟出。
研末，和前药末饭
《本事方》破阴丹∶治阴中伏阳，烦躁，六脉沉伏。硫黄、水银各一两，陈皮、青皮各
五钱
冷
《伤寒百问》方∶硫黄五钱。艾汤调下。治身冷脉微，厥而烦躁。令卧，汗出愈。
黑锡丹∶黑铅 硫黄各二两。将锡熔化，渐入硫黄，候结成片，倾地上出火毒，研至无
声为度。治阴阳不升降，上盛下虚，头目眩运。
【补火丸】治疗冷劳（因寒邪久留导致的虚损）、气血枯竭、肌肉消瘦、牙齿脱落、肢体倦怠、声音低微。吴鹤皋说：大凡人的身体里有真火，寄居在右肾，运行于三焦，出入于胆经，听命于心神（天君），所以温暖全身骨骼、滋养脏腑、充盈九窍的，都是这股火。它是万物的父亲，所以说“没有这把火，天地不能化生万物；没有这把火，人不能有生命”。如果这把火有一息停止，就像万物失去了父亲，所以肌肉衰弱而消瘦，血液衰弱而干枯，骨骼衰弱而牙齿脱落，筋脉衰弱而肢体倦怠，气衰弱而声音低微。
石硫黄（一斤），猪大肠（二尺）。将硫黄研成粉末，填入猪肠中，煮至烂熟，历时三个时辰，取出后去掉猪肠，用蒸饼做药丸，大小如梧桐子。每次服用十丸，逐渐增加剂量。（凡是服用硫黄的人，忌食各种禽兽的血。）
这是足少阴肾经命门穴的药物。硫黄是火的精华，也被称为将军（大黄极寒，也被称为将军），所以用它来补火；因为它大热且有剧毒，所以用猪肠长时间煮制以解除其毒性；庸俗之人忌讳它而很少使用，大概不知道它有破除邪气、回归正气、消除阴寒、恢复阳气、化解阴浊、生成阳气的力量。（吴鹤皋说：戴元礼曾说，所有的凉性药物都容易凝滞，所有的热性药物都容易燥烈，只有硫黄热而不燥。过去仁和的一位小吏早衰，服用它活到了九十岁。其他如范仲淹的金液丹，《得效方》的玉真丸，《太平惠民和剂局方》的来复丹、半硫丸、灵砂丹，《百选方》的二气丹，《伤寒总病论》的返阴丹，杨氏的紫霞丹都使用了硫黄，只是主治各有侧重罢了。汪昂按语：人有真阳虚衰，附子、肉桂所不能补的，非硫黄不能补；现在的人认为它燥毒，抛弃而不使用，不知道硫黄性质虽然燥但具有疏利作用，与燥涩的药物不同。本草称它为救危妙药，道家用来服食，尊称为金液丹，确实是人们可以常服的药物；而且硝石与硫黄，一阴一阳，但都是同类之物，现在的人只知道用芒硝……）
附注：
金液丹：硫黄（十两）。研成粉末，盛在瓷盆里。用水调和赤石脂封口，用盐泥加固密封，晒干；在地上埋一个小罐，装满水，把盆放在里面，用泥加固密封。用慢火煅烧七天七夜，加入一斤顶火（指火候达到顶点），取出，研成粉末，用蒸饼做丸。
玉真丸：生硫黄（二两），生硝石，石膏，半夏（一两）。用姜汁糊做丸。用姜汤或米饮送下，每次四十丸。
来复丹：太阴元精石，舶上硫黄，硝石（一两，硝石和硫黄一起微炒，不可火太大，用柳条搅拌结成砂子状），五灵脂（去除砂石），青皮，陈皮（一两）。用醋糊做丸。用米饮送下。治疗伏暑泄泻，身体发热，脉象微弱。（《玉机微义》说：硝石性寒，佐以陈皮，其性疏快，硫黄能通利人体，如果把它当作暖药来止泻，就错了。这是由于吃生冷食物，或者冒受暑热，导致中脘闭塞结聚，突然发生紊乱，此药能通利三焦，分理阴阳，服用非常有效。如果是由于暑火湿热引起的则不要使用。）
半硫丸：半夏，硫黄，等分。用生姜糊做丸。治疗老人虚秘、冷秘。
灵砂丹：水银三两，硫黄（一两）。炼成后研成粉末，用糯米糊做丸。治疗各种虚损痼冷。
二气丹：硝石，硫黄，等分。研成粉末。在石器中炒成砂状，再研磨，用糯米糊做丸，大小如梧桐子。每次服用四十丸，井水送下。治疗伏暑伤冷，二气交错，中脘痞塞结聚，或者呕吐或者腹泻，霍乱厥逆。
返阴丹：治疗阴毒伤寒，心神烦躁，四肢逆冷。硫黄五两，硝石，太阴元精石一两，附子（炮制），干姜（炮制），桂心（五钱）。用铁锅先铺一半元精末，其次铺一半硝石末，中间放入硫黄末，再用一半硝石盖住硫黄，最后再以元精末盖上。用小盏覆盖，用三斤炭火煅烧，使其适度，不要让烟冒出。研成粉末，和前药末混合，用饭做丸。
《本事方》破阴丹：治疗阴中伏阳，烦躁，六脉沉伏。硫黄、水银各一两，陈皮、青皮各五钱。
《伤寒百问》方：硫黄五钱。用艾汤调下。治疗身体寒冷，脉象微弱，厥逆而烦躁。让病人躺卧，出汗后痊愈。
黑锡丹：黑铅，硫黄各二两。将铅熔化，逐渐加入硫黄，等到结成片状，倒在地下以去除火毒，研磨直到没有声音为止。治疗阴阳不升降，上盛下虚，头目眩晕。
[Supplementing Fire Pill] Treats cold lao (deficiency syndrome caused by long-term retention of cold pathogen), exhaustion of qi and blood, emaciation of flesh, loss of teeth, lassitude of limbs, and faint voice. Wu Hegao stated: In the human body, there is a True Fire, residing in the right kidney, circulating through the Sanjiao (Triple Burner), entering and exiting the Gallbladder Meridian, and obeying the Heavenly Lord (Heart Spirit/Shen). It warms the hundred bones, nourishes the zang-fu organs, and fills the nine orifices; all this is due to this fire. It is the father of all things, hence it is said that "without this fire, heaven and earth cannot generate living things; without this fire, humans cannot have life." If this fire ceases for even a breath, it is like all things losing their father. Thus, flesh becomes weak and emaciated, blood becomes weak and withered, bones become weak and teeth fall out, sinews become weak and limbs become lazy, qi becomes weak and voice becomes faint.
Shihuanghuang (Cinnabar Sulfur / Realgar? No, Shihuanghuang is Sulfur) (one jin), Zhu Dachang (Pig Large Intestine) (two chi). Grind the sulfur into powder, fill it into the pig intestine, boil until rotten/cooked thoroughly for three shi (six hours), remove and discard the intestine, make pills using steamed bread dough, sized like wutong seeds. Take ten pills per dose, gradually increasing the amount daily. (Those taking sulfur must avoid eating blood from poultry and beasts.)
This is a medicine for the Mingmen (Gate of Life) of the Foot-Shaoyin Kidney Meridian. Sulfur is the essence of fire, also known as the General (Dahuang, being extremely cold, is also called the General). Therefore, it is used to supplement fire; because it is extremely hot and slightly toxic, it is boiled in pig intestines for a long time to resolve its toxicity. Vulgar people fear it and rarely use it, likely unaware of its power to break evil and return to righteousness, eliminate yin and restore yang, transform turbidity and generate spirit. (Wu Hegao said: Dai Yuanli stated that all cooling medicines tend to cause stagnation, and all heating medicines tend to be drying, but only sulfur is hot without being drying. In the past, a clerk from Renhe suffered from premature aging and took it, living to ninety years old. Others include Fan Zhongyan's Jin Ye Dan, the Yu Zhen Wan from *De Xiao Fang*, Lai Fu Dan, Ban Liu Wan, Ling Sha Dan from *Tai Ping Hui Min He Ji Ju Fang*, Er Qi Dan from *Bai Xuan Fang*, Fan Yin Dan from *Shang Han Zong Bing Lun*, and Zi Xia Dan from Yang Shi, all of which use sulfur, though each has its specific indications. Wang Ang notes: When humans suffer from deficiency and decline of True Yang, which Fuzi and Rougui cannot supplement, only sulfur can supplement it; nowadays people consider it drying and toxic, discarding it without use, not knowing that although sulfur is drying, it has a dispersing and purgative nature, different from drying and astringent substances. Materia Medica calls it a miraculous medicine for saving critical conditions, Daoists use it for ingestion, honoring it as Jin Ye Dan, and it is indeed a substance people can take regularly; moreover, Xiaosha (Niter) and Huanghuang (Sulfur) are one yin and one yang, yet they are similar in nature. Nowadays people only know how to use Mangxiao...)
Appendix:
Jin Ye Dan (Golden Liquid Pill): Shihuanghuang (ten liang). Grind into powder, place in a porcelain basin. Seal with water mixed with Chishizhi (Red Stone Lipid), reinforce with salt mud, dry in the sun; bury a small jar filled with water in the ground, place the basin inside, seal tightly with mud. Nourish with slow fire for seven days and nights, add top-level fire (intense heat) of one jin, remove, grind into powder, make pills with steamed bread.
Yu Zhen Wan (Jade True Pill): Sheng Shihuanghuang (Raw Sulfur) (two liang), Sheng Xiaosha (Raw Niter), Shigao (Gypsum Fibrosum), Banxia (Pinellia Rhizoma) (one liang). Make pills with ginger juice paste. Take with ginger soup or rice drink, forty pills per dose.
Lai Fu Dan (Returning Recovery Pill): Taiyin Yuanjing Shi (Taiyuan Crystal Stone), Boshang Shihuanghuang (Imported Sulfur), Xiaosha (Niter) (one liang, stir-fry niter and sulfur lightly together, do not use high heat, stir with willow twig until it forms sand-like grains), Wulingzhi (Trogopterus Dung) (remove stones), Qingpi (Aurantii Fructus Immaturus), Chenpi (Aurantii Fructus Pericarpium) (one liang). Make pills with vinegar paste. Take with rice drink. Treats latent summerheat diarrhea, fever, and weak pulse. (*Yuji Wei Yi* states: Niter is cold in nature; assisted by Chenpi, its nature is dispersing and unblocking. Sulfur benefits the person. If used as a warming medicine to stop diarrhea, it is a mistake. This condition arises from consuming raw/cold foods or exposure to summerheat, causing closure and stagnation in the middle jiao, leading to sudden turmoil. This medicine unblocks the Sanjiao, separates and regulates yin and yang, and is very effective. Do not use if caused by summerheat-fire or damp-heat.)
Ban Liu Wan (Half-Sulfur Pill): Banxia (Pinellia Rhizoma), Shihuanghuang (Sulfur), equal parts. Make pills with ginger paste. Treats elderly deficiency constipation and cold constipation.
Ling Sha Dan (Spirit Sand Pill): Shuiyin (Mercurius) (three liang), Shihuanghuang (Sulfur) (one liang). Calcine and grind into powder, make pills with glutinous rice paste. Treats various deficiency syndromes and chronic cold.
Er Qi Dan (Two Qi Pill): Xiaosha (Niter), Shihuanghuang (Sulfur), equal parts. Grind into powder. Stir-fry in a stone vessel until it becomes sand, then grind again, make pills with glutinous rice paste, sized like wutong seeds. Take forty pills per dose with well water. Treats latent summerheat injuring cold, intermingling of two qi, epigastric fullness and obstruction, vomiting or diarrhea, cholera with cold extremities.
Fan Yin Dan (Returning Yin Pill): Treats yin-toxin cold damage, mental restlessness and irritability, cold extremities. Shihuanghuang (Sulfur) (five liang), Xiaosha (Niter), Taiyin Yuanjing Shi (Taiyuan Crystal Stone) (one liang), Fuzi (Prepared Aconiti Lateralis Radix), Ganjiang (Prepared Zingiberis Rhizoma), Guixin (Cinnamon Twig Heart) (five qian). Use an iron pot, first spread half of the Yuanjing powder, then half of the Niter powder, place Sulfur powder in the middle, cover with half of the Niter powder, and finally cover with Yuanjing powder. Cover with a small cup, burn with three jin of charcoal, control the heat properly, do not let smoke escape. Grind into powder, mix with previous powders, make pills with rice.
*Ben Shi Fang* Po Yin Dan (Yin-Breaking Pill): Treats hidden yang within yin, irritability, deep and hidden six pulses. Shihuanghuang (Sulfur), Shuiyin (Mercury) each one liang, Chenpi (Citri Reticulatae Pericarpium), Qingpi (Aurantii Fructus Immaturus) each five qian.
*Shang Han Bai Wen* Formula: Shihuanghuang (Sulfur) (five qian). Mix with mugwort soup and take. Treats cold body, faint pulse, cold extremities with irritability. Let the patient lie down; recovery occurs when sweat appears.
Hei Xi Dan (Black Tin Pill): Heiqian (Lead) and Shihuanghuang (Sulfur) each two liang. Melt the lead, gradually add sulfur, wait until it forms sheets, pour onto the ground to remove fire toxicity, grind until no sound is produced. Treats non-circulation of yin and yang, excess above and deficiency below, dizziness of head and eyes.