【木位之主】 其泻以酸，其补以辛；厥阴之客，以辛补之，以酸泻之，以甘缓之。
【火位之主】 其泻以甘，其补以咸；少阴之客，以甘泻之，以咸收之；少阳之客，以咸
补之，以甘泻之，
以咸软之。
【土位之主】 其泻以苦，其补以甘；太阴之客，以甘补之，以苦泻之，以甘缓之。
【金位之主】 其泻以辛，其补以酸；阳明之客，以酸补之，以辛泻之，以苦泄之。
【水位之主】 其泻以咸，其补以苦；太阳之客，以苦补之，以咸泻之，以苦坚之，以辛
润之。（客胜则泻客补主，主胜则泻主补客，随其缓急以施治之。）
《内经》曰∶天地之气内淫而病，治之奈何？曰∶诸气在泉，风淫于内，治以辛凉，佐以
苦甘，以甘缓之，以辛散之。热淫于内，治以咸寒，佐以甘苦，以酸收之，以苦发之。湿淫于
内，治以苦热，佐以酸淡，以苦燥之，以淡泄之。火淫于内，治以咸冷，佐以苦辛，以酸收之，
以苦发之。燥淫于内，治以苦温，佐以甘辛，以苦下之。寒淫于内，治以甘热，佐以苦辛，以
咸泻之，以辛润之，以苦坚之。
帝曰∶有毒无毒，服有约乎？岐伯曰∶病有新久，方有大小，有毒无毒，固宜当制矣。其
大毒治病，十去其六；常毒治病，十去其七；小毒治病，十去其八；无毒治病，十去其九。谷、
肉、菜、果、食养尽之，无使过之，伤其正也。不尽，行复如法，必先岁气，无伐天和。无代
化，无违时，调养必和，待其来复。又曰∶大积大聚，其可犯也，衰其大半而止，过者死。
【木位之主】对于木气主令的时节，其泻法用酸味药，其补法用辛味药；若是厥阴风木之气客居（邪犯），用辛味药来补益它，用酸味药来泻除它，用甘味药来缓和它。
【火位之主】对于火气主令的时节，其泻法用甘味药，其补法用咸味药；若是少阴君火之气客居，用甘味药来泻除它，用咸味药来收敛它；若是少阳相火之气客居，用咸味药来补益它，用甘味药来泻除它，用咸味药来软坚散结。
【土位之主】对于土气主令的时节，其泻法用苦味药，其补法用甘味药；若是太阴湿土之气客居，用甘味药来补益它，用苦味药来泻除它，用甘味药来缓和它。
【金位之主】对于金气主令的时节，其泻法用辛味药，其补法用酸味药；若是阳明燥金之气客居，用酸味药来补益它，用辛味药来泻除它，用苦味药来通泄它。
【水位之主】对于水气主令的时节，其泻法用咸味药，其补法用苦味药；若是太阳寒水之气客居，用苦味药来补益它，用咸味药来泻除它，用苦味药来坚固它，用辛味药来滋润它。（如果是客气胜则泻客气、补主气，如果是主气胜则泻主气、补客气，根据病情的缓急来实施治疗。）
《黄帝内经》说：天地之气侵入体内而导致疾病，该如何治疗？回答说：凡是六气在泉（主岁之气），风气淫溢于内，用辛凉的药物来治疗，辅以苦甘药物，用甘味药来缓和，用辛味药来发散。热气淫溢于内，用咸寒的药物来治疗，辅以甘苦药物，用酸味药来收敛，用苦味药来发散。湿气淫溢于内，用苦热的药物来治疗，辅以酸淡药物，用苦味药来燥湿，用淡味药来渗泄。火气淫溢于内，用咸冷的药物来治疗，辅以苦辛药物，用酸味药来收敛，用苦味药来发散。燥气淫溢于内，用苦温的药物来治疗，辅以甘辛药物，用苦味药来攻下。寒气淫溢于内，用甘热的药物来治疗，辅以苦辛药物，用咸味药来泻下，用辛味药来滋润，用苦味药来坚固。
黄帝问：有毒或无毒的药物，服用有定规吗？岐伯回答：疾病有新发与久病之分，方剂有大制与小制之别，无论有毒无毒，都应当制定适宜的剂量。使用大毒药物治疗，病去十分之六即止；使用常毒药物治疗，病去十分之七即止；使用小毒药物治疗，病去十分之八即止；使用无毒药物治疗，病去十分之九即止。剩下的病邪，通过谷物、肉类、蔬菜、水果等饮食调养来彻底清除，不要使治疗过度，以免损伤人体的正气。如果病邪未尽，按照上述法则再次治疗，但必须先了解当年的岁气特点，不要违背自然的和谐规律。不要替代自然化生的规律，不要违逆四时气候的变化，调养必须平和，等待人体正气的恢复。又说：对于大的积聚病症，可以使用猛药攻伐，但病势衰退大半时就应停止，若过度攻伐会导致死亡。
[The Ruler of the Wood Position] For the season when Wood Qi governs, its draining method employs Sour substances, and its tonifying method employs Pungent substances. When Jueyin (Liver/Gallbladder) Wind-Moisture acts as a guest pathogen, use Pungent substances to tonify it, Sour substances to drain it, and Sweet substances to relax it.
[The Ruler of the Fire Position] For the season when Fire Qi governs, its draining method employs Sweet substances, and its tonifying method employs Salty substances. When Shaoyin (Heart/Kidney) Ministerial-Fire acts as a guest pathogen, use Sweet substances to drain it, and Salty substances to consolidate it. When Shaoyang (Sanjiao/Gallbladder) Ministerial-Fire acts as a guest pathogen, use Salty substances to tonify it, Sweet substances to drain it, and Salty substances to soften hardness.
[The Ruler of the Earth Position] For the season when Earth Qi governs, its draining method employs Bitter substances, and its tonifying method employs Sweet substances. When Taiyin (Spleen/Stomach) Dampness acts as a guest pathogen, use Sweet substances to tonify it, Bitter substances to drain it, and Sweet substances to relax it.
[The Ruler of the Metal Position] For the season when Metal Qi governs, its draining method employs Pungent substances, and its tonifying method employs Sour substances. When Yangming (Large Intestine/Lung) Dryness acts as a guest pathogen, use Sour substances to tonify it, Pungent substances to drain it, and Bitter substances to purge it.
[The Ruler of the Water Position] For the season when Water Qi governs, its draining method employs Salty substances, and its tonifying method employs Bitter substances. When Taiyang (Bladder/Kidney) Cold acts as a guest pathogen, use Bitter substances to tonify it, Salty substances to drain it, Bitter substances to firm it, and Pungent substances to moisten it. (If the Guest Qi is victorious, drain the Guest and tonify the Host; if the Host Qi is victorious, drain the Host and tonify the Guest. Treat according to the urgency of the condition.)
The *Huangdi Neijing* (Yellow Emperor's Inner Canon) states: When the Qi of Heaven and Earth invades internally causing disease, how should it be treated? It is said: Regarding the Six Qi governing from below (Di Qiu), if Wind Yin overflows internally, treat with Pungent-Cold substances, assist with Bitter-Sweet substances, use Sweet substances to relax, and Pungent substances to disperse. If Heat Yin overflows internally, treat with Salty-Cold substances, assist with Sweet-Bitter substances, use Sour substances to collect, and Bitter substances to vent. If Dampness Yin overflows internally, treat with Bitter-Hot substances, assist with Sour-Insipid substances, use Bitter substances to dry, and Insipid substances to drain. If Fire Yin overflows internally, treat with Salty-Cool substances, assist with Bitter-Pungent substances, use Sour substances to collect, and Bitter substances to vent. If Dryness Yin overflows internally, treat with Bitter-Warm substances, assist with Sweet-Pungent substances, and use Bitter substances to purge downward. If Cold Yin overflows internally, treat with Sweet-Hot substances, assist with Bitter-Pungent substances, use Salty substances to purge, Pungent substances to moisten, and Bitter substances to firm.
The Yellow Emperor asked: Is there a regulation for taking toxic or non-toxic medicines? Qibo replied: Diseases vary in being new or chronic, and prescriptions vary in size. Whether toxic or non-toxic, they must be properly regulated. When using Great Toxicity drugs to treat disease, stop when six-tenths of the disease is removed; when using Common Toxicity drugs, stop when seven-tenths are removed; when using Small Toxicity drugs, stop when eight-tenths are removed; when using Non-Toxic drugs, stop when nine-tenths are removed. Use grains, meats, vegetables, and fruits for dietary nourishment to clear the remainder. Do not let treatment go too far, lest it damage Zheng Qi (Upright Qi). If the disease is not fully resolved, repeat the process according to these rules. First, consider the annual Qi, and do not violate the harmony of Heaven and Nature. Do not replace natural transformation, do not go against the seasons, ensure nourishment and regulation are harmonious, and wait for recovery. It is also said: For large accumulations and masses, one may employ aggressive treatments, but stop when more than half of the accumulation has diminished; exceeding this limit leads to death.