It is stated that the Five Zang organs and Six Fu organs all possess Jing (Essence). When the Zang and Fu organs are harmonious, Jing can be transported and excreted normally; if the Zang and Fu organs decline, the physical form becomes extremely depleted, causing shortness of breath and labored respiration. Internal deficiency of the Five Zang organs leads to scorched teeth and falling hair, sadness and forgetfulness, blurred vision, deafness, unsteady gait, and heavy body. These are all signs of extreme Jing depletion. However, extreme Jing depletion can be either extreme deficiency or extreme excess. Generally, Yang pathogens harm the Five Zang organs, while Yin pathogens harm the Six Fu organs. In cases of Yang excess, treatment should guide from the Yin meridians to the Yang meridians; in cases of Yin deficiency, treatment should guide from the Yang meridians to the Yin meridians. Yang diseases primarily manifest in the upper part; upper manifestations indicate excess heat, which is suitable for purging internal heat. Yin diseases primarily manifest in the lower part; lower manifestations indicate deficiency cold, resulting in heavy body, deafness, and unsteady gait. If pathogens enter the Zang organs, coughing occurs, leading to excessive phlegm and saliva, facial swelling, and rebellious Qi. This indicates pathogens rebelling in the Six Fu organs and flooding into the Five Zang organs with deficiency and jue (collapse), causing extreme Jing depletion. The treatment principle is: for those with insufficient physical form, warm them with Qi-tonifying methods; for those with insufficient Jing, tonify them with flavor-rich substances. Treatment should begin when the condition is mild. If it progresses to the point where the Qi of the Five Yin organs is completely exhausted, the eye tendons will turn, and the essence of the eyes will be depleted. This is called "Zhi" (Will) dying first, and it is incurable.

Formula for Ren Shen Wan (Ginseng Pill) treating extreme Jing depletion with deficiency-cold, hypochondriac tension, deafness, hair loss, unsteady gait, and nocturnal emission:
Ren Shen (Panax Ginseng Radix et Rhizoma), Mai Men Dong (Ophiopogonis Tuber, heart removed and dried), Chi Shi Zhi (Halloysit Rubra), Yuan Zhi (Polygalae Radix, heart removed), Xu Duan (Dipsaci Radix) [each 3 fen], Jiu Zi (Allii Tuberosi Semen, stir-fried, 1 liang), Lu Rong (Cervi Cornu Pantotrichum, hair removed, roasted with butter, 3 fen), Fu Shen (Poria with Hostwood, wood removed), Long Gu (Fossilia Ossis Mastodi, ground), Ci Shi (Magnetitum, quenched in vinegar), Rou Cong Rong (Cistanches Herba, soaked in wine, sliced, and dried, each 1 liang), Dan Shen (Salviae Miltiorrhizae Radix et Rhizoma).
The above fourteen ingredients are crushed, sifted into powder, and mixed with refined honey to form pills the size of Sophora seeds. Take twenty pills orally with warm wine on an empty stomach daily.

Formula for Lu Rong San (Deer Antler Powder) treating extreme Jing depletion and deficiency, nocturnal emission, weak Yin Qi, hypochondriac tension, heavy body, and deafness:
Lu Rong (Cervi Cornu Pantotrichum, hair removed, roasted with butter), Long Gu (Fossilia Ossis Mastodi), Lu Feng Fang (Vespa Crabro Nidus, roasted) [each half liang], Ze Xie (Alismatis Rhizoma), Bai Fu Ling (Poria, black skin removed), Tu Si Zi (Cuscutae Semen, soaked in wine overnight and separately pounded), Gui (Cinnamomi Ramulus, rough bark removed), Niu Xi (Achyranthis Bidentatae Radix, soaked in wine, sliced, and dried), Shi Long Rui (Saururi Herba), Chi Shao Yao (Paeoniae Radix Rubra) [each 1 fen], Jiu Zi (Allii Tuberosi Semen, stir-fried, 2 liang), Ba Ji Tian (Morindae Officinalis Radix, heart removed, 3 fen).
The above twelve ingredients are crushed and sifted into powder. Take three qian bi orally, mixed with warm wine on an empty stomach, twice daily. Alternatively, mix with refined honey to form pills the size of Sophora seeds, taking twenty pills orally with warm wine on an empty stomach. Adding Sang Piao Xiao (Mantis Ootheca, 3 fen) is also acceptable.

Formula for Huang Qi Tang (Astragalus Decoction) treating extreme Jing depletion with internal injury to Kidney Qi, nocturnal seminal emission, night sweats, dribbling urine, impotence, damp itching in the genital area, and rigid/tense hypochondrium:
Huang Qi (Astragali Membranacei Radix, chopped), Ren Shen (Panax Ginseng Radix et Rhizoma), Chi Shao Yao (Paeoniae Radix Rubra), Gui (Cinnamomi Ramulus, rough bark removed), Di Gu Pi (Lycii Cortex), Wu Wei Zi (Schisandrae Chinensis Fructus), Bai Fu Ling (Poria, black skin removed), Fang Feng (Saposhnikoviae Radix, forked parts removed), Chen Ju Pi (Citri Reticulatae Pericarpium, soaked in hot water, white pith removed, and dried, each half liang), Gan Cao (Glycyrrhizae Radix et Rhizoma, roasted and chopped), Ci Shi (Magnetitum, quenched in vinegar seven times), Mu Li Fen (Ostreae Concha, powdered) [each 1 fen].
The above twelve ingredients are coarsely crushed and sifted. Take three qian bi orally, with one sheng of water, half a jujube-sized piece of fresh ginger (crushed), and two jujubes (split). Decoct until the volume reduces to 70%, strain, and take warm before meals on an empty stomach, three times daily.

Formula for Di Huang Yin (Rehmannia Infusion) treating extreme Jing depletion with damage to both Zang and Fu organs, generalized deficiency-heat, and painful joints:
Sheng Di Huang (Rehmanniae Radix, juice), Sheng Mai Men Dong (Ophiopogonis Tuber, juice), Mi (Honey) [each 2 he], Zhu Li (Bambusa Textilis Caulis, juice, 1 he), Shi Gao (Gypsum Fibrosum, 2.5 liang, ground), Ren Shen (Panax Ginseng Radix et Rhizoma), Xiong Huang (Ligustici Chuanxiong Rhizoma), Huang Qin (Scutellariae Radix, black heart removed, each 1.5 liang), Dang Gui (Angelicae Sinensis Radix, sliced and dried), Gui (Cinnamomi Ramulus, rough bark removed, each 2 liang), Ma Huang (Ephedrae Herba, roots and nodes removed, 1 liang), Gan Cao (Glycyrrhizae Radix et Rhizoma, roasted and chopped, 1.5 liang).
The above twelve ingredients, excluding Sheng Di Huang, Sheng Mai Men Dong, Zhu Li, and Mi, are coarsely crushed and sifted. Take five qian bi orally, with one and a half sheng of water. Decoct until the volume reduces to one sheng. Add half a he each of the juices from Sheng Di Huang, etc., boil for one or two more boils, strain, and divide into two warm doses. Take one dose on an empty stomach and one after meals.

Formula for Huang Qin Tang (Scutellaria Decoction) treating extreme Jing depletion with blurred vision, scorched teeth, hair loss, physical pain, and body deficiency-heat:
Huang Qin (Scutellariae Radix, black heart removed), Chi Fu Ling (Poria, black skin removed, each 1.5 liang), Mai Men Dong (Ophiopogonis Tuber, heart removed and dried), Da Huang (Rhei Radix et Rhizoma, chopped and stir-fried, each 1 liang), Chi Shao Yao (Paeoniae Radix Rubra).
The above seven ingredients are coarsely crushed and sifted. Take five qian bi orally, with one and a half sheng of water, five leaves of Zhu Ye (Bambusa Textilis Folium), and a jujube-sized piece of fresh ginger (crushed). Decoct until the volume reduces to one sheng, strain, and divide into two warm doses to be taken after meals.

Formula for Di Huang Jian Wan (Rehmannia Paste Pill) treating extreme Jing depletion with emaciation of Zang and Fu organs, painful joints, continuous seminal leakage, having effects of benefiting Qi, nourishing Spirit, preserving complexion, and regulating blood vessels:
Sheng Di Huang (Rehmanniae Radix, 5 jin, pounded to extract juice), Wu Hui Jiu (Wine without ash, 1 dou, stored in silver or earthenware vessel, added to Di Huang juice, boiled down to paste using gentle and strong fire, then other herbs added), Rou Cong Rong (Cistanches Herba, soaked in wine, sliced, and dried, 2 liang), Ba Ji Tian (Morindae Officinalis Radix, heart removed), Lu Rong (Cervi Cornu Pantotrichum, wine-roasted, hair removed), Sang Piao Xiao (Mantis Ootheca, stir-fried), Fu Zi (Aconiti Lateralis Radix Praeparata, cracked by frying, skin and umbilicus removed), Huang Qi (Astragali Membranacei Radix, chopped), Rou Dou Kou (Myristicae Semen, shell removed), Wu Wei Zi (Schisandrae Chinensis Fructus, stir-fried), She Chuang Zi (Cnidii Fructus, stir-fried), Shi Hu (Dendrobii Caulis, roots removed), Bu Gu Zhi (Psoraleae Fructus, stir-fried), Niu Xi (Achyranthis Bidentatae Radix, soaked in wine, sliced, and dried), Qing Mu Xiang (Aucklandiae Radix), Chen Ju Pi (Citri Reticulatae Pericarpium, soaked in hot water, white pith removed, and dried, each 3 fen), Zhi Ke (Aurantii Fructus Immaturus, pulp removed, stir-fried with bran), Bi Cheng Qie (Piperis Longi Fructus), Chen Xiang (Aquilariae Lignum Resinatum, each half liang, chopped).
The above nineteen ingredients: seventeen ingredients (excluding the Di Huang paste) are crushed and sifted into powder. Mix with Di Huang paste to form pills the size of Sophora seeds. Take thirty pills orally with warm wine, increasing up to forty pills. Take on an empty stomach before meals.