（论三首 证十八条 方三十七首）
论曰∶人不服石，以庶事不佳，恶疮疥癣，温疫疟疾，年年常患，寝食不安，兴居常恶
，非只己事不康，生子难育，所以石在身中，万事休泰，要不可服五石也。人年三十以上可
服石药，若素肥充亦勿妄服。四十以上必须服之。五十以上三年可服一剂，六十以上二年可
服一剂，七十以上一年可服一剂。
又曰∶人年五十以上，精华消歇，服石犹得其力。六十以上转恶，服石难得力。所以常
须服石，令人手足温暖，骨髓充实，能消生冷，举措轻便，复耐寒暑，不着诸病。是以大须
服之。凡石皆熟炼用之。凡石之发，当必恶寒头痛心闷，发作有时，状如温疟，但有此兆，
无过取冷水淋之，得寒乃止。一切冷食唯酒须温，其诸解法备如后说。其发背疽肿（方见二
十二卷中）。
又曰∶凡服石人，慎不得杂食口味，虽百品具陈，终不用重食其肉，诸杂既重，必有相
贼，积聚不消，遂动诸石，如法持心，将摄得所。石药为益，善不可加。余年三十八九尝服
五六两乳，自是以来深深体悉，至于将息节度，颇识其性，养生之士宜留意详焉。然其乳石
必须土地清白光润，罗纹鸟翮一切皆成，乃可入服。其非土地者，慎勿服之，多致杀人。甚
于鸩毒、紫石、白石极须外内映澈，光净皎然，非尔亦不可服。寒石五石更生散方，旧说此
药方，上古名贤无此，汉末有何侯者行用，自皇甫士安以降，有进饵者，无不发背解体，而
取颠覆。余自有识性以来，亲见朝野仕人遭者不一，所以宁食野葛，不服五石，明其有大大
猛毒，不可不慎也。有识者遇此方即须焚之，勿久留也。今但录主对以防先服者，其方已从
烟灭，不复须存，为含生害也。
（论述三篇，证候十八条，方剂三十七首）
论述说：人如果不服用石药，往往诸事不顺，容易患有恶疮、疥癣、温疫、疟疾等疾病，年年反复发作，导致睡眠和饮食都不安稳。这不仅自己身体不健康，连生育的孩子也难以养育。所以，如果体内有石药，万事都会安宁顺遂，但关键在于不能随意服用“五石散”。年龄在三十岁以上的人可以服用石药，如果平时身体肥胖健壮，也不要妄自服用。四十岁以上的人必须服用。五十岁以上的人，每三年可以服用一剂；六十岁以上的人，每两年可以服用一剂；七十岁以上的人，每年可以服用一剂。
又说：人到了五十岁以上，精气神逐渐衰退，此时服用石药还能得到其效力。六十岁以上的人，效果就会变差，服用石药很难再获得功效。因此，经常需要服用石药，使人手足温暖，骨髓充实，能够消化生冷食物，举止行动轻便，又能抵御寒暑侵袭，不遭受各种疾病。所以非常需要服用它。所有的石药都必须经过熟炼处理后使用。凡是石药发作时，必然会出现恶寒、头痛、心中闷胀等症状，发作有定时，症状类似温疟。只要出现这些征兆，不要超过限度，用冷水淋洗即可，感到寒冷后症状就会停止。所有冷食除了酒需要温热外，其他解法详见后文说明。如果发生发背疽肿（方剂见第二十二卷中）。
又说：凡是服用石药的人，务必注意不得混杂食用味道浓烈的食物。即使有一百种美食陈列在面前，最终也不应多吃肉类。因为各种杂味过于厚重，必然会产生相互克制的作用，导致积聚之物无法消散，从而触动体内的石药。如果能依法保持心境平和，调养得当，石药的益处就没有什么能超过的了。我年纪三十八九岁时曾服用过五六两乳石，从此以后深深体会其中奥妙，对于调养节制的度，颇识其特性，养生之士应当留意并详细研究。然而，其中的乳石必须是土地清净、色泽白光润、纹理如罗纹、鸟羽般完整无损的，才可以入药服用。如果不是产自特定土地的，千万不要服用，否则多会导致死亡。其毒性甚至超过鸩毒。紫石、白石必须内外通透，光洁明亮，如果不是这样，也不可服用。关于寒石五石更生散的方子，旧时说此药方上古名贤没有，汉末有何侯开始推行使用，从皇甫士安以来，有人进服此药，无不引发发背疽或身体解体，导致倾覆败亡。我自懂事以来，亲眼见到朝廷和民间仕人遭遇此害者不在少数，所以我宁愿吃野葛（一种剧毒植物），也不服用五石散，明确知道它有巨大的猛烈毒性，不可不谨慎。有见识的人遇到这个方子就必须烧毁它，不要久留。现在只记录主治对证以防先服者受害，其方已从烟灭，不再需要保存，以免伤害众生。
(Three Discourses, Eighteen Symptom Patterns, Thirty-Seven Formulas)
Discourse: If people do not take mineral drugs (Shiyao), they often experience poor fortune in various affairs, suffering from malignant sores (Echuang), scabies and tinea (Jiexuan), warm epidemics (Wenyi), and malaria (Nueji). These conditions recur annually, causing restlessness in sleep and appetite. This not only leads to personal ill health but also makes it difficult to raise offspring. Therefore, having mineral substances in the body ensures peace and prosperity in all matters; however, one must strictly avoid taking the "Five Minerals Powder" (Wushi San). Individuals aged thirty and above may take mineral drugs. If one is naturally plump and robust, one should not take them recklessly. Those aged forty and above must take them. For those aged fifty and above, one dose may be taken every three years; for those aged sixty and above, one dose every two years; and for those aged seventy and above, one dose annually.
It is also said: By the age of fifty, the essence and vitality decline. Taking mineral drugs at this stage can still yield their efficacy. After sixty, the effect diminishes, and it becomes difficult to derive benefit from mineral drugs. Therefore, regular intake is necessary to keep the hands and feet warm, fill the bone marrow, aid in digesting raw and cold foods, ensure lightness of movement, resist cold and heat, and prevent various diseases. Thus, it is highly recommended. All minerals must be calcined and processed before use. When mineral drugs manifest their effects, symptoms such as aversion to cold (Ehan), headache (Toutong), and chest oppression (Xinmen) inevitably occur, with periodic onset resembling warm malaria (Wen Nue). Upon observing these signs, one should not exceed limits; washing with cold water will suffice, and the symptoms will cease upon feeling cold. Regarding all cold foods, only wine needs to be warmed; other detoxification methods are detailed below. If a carbuncle on the back (Fabeiju Zhong) occurs, refer to Volume 22 for the formula.
Furthermore, those taking mineral drugs must be cautious about mixing strong-flavored foods. Even if a hundred varieties of delicacies are presented, one should ultimately avoid consuming heavy amounts of meat. Since mixed flavors are too rich, they inevitably interact negatively, causing accumulations that fail to dissipate, thereby triggering the mineral drugs. If one maintains mental discipline according to the rules and manages diet properly, the benefits of mineral drugs cannot be surpassed. At the age of thirty-eight or thirty-nine, I once took five or six liang of Milk Stone (Rushi). Since then, I have deeply understood its nature. Regarding regulation and care, I am quite familiar with its properties. Scholars of longevity should pay close attention to this. However, the Milk Stone must come from pure land, be white and lustrous, possess patterns like silk gauze, and resemble intact bird feathers. Only then can it be ingested. Stones not from such lands must never be taken, as they often cause death. Their toxicity exceeds that of Zhen poison (Zhen Du). Purple Stone (Zishi) and White Stone (Baishi) must be transparent inside and out, bright and clean; otherwise, they are unfit for use. Regarding the formula for Cold Mineral Five Minerals Gengsheng San (Han Shi Wushi Gengsheng San), old texts state that ancient sages did not have this prescription. It was practiced by He Hou in the late Han Dynasty. From Huangfu Mi (Huangfu Shian) onwards, those who ingested it invariably suffered from back carbuncles or bodily disintegration, leading to ruin. Since my youth, I have personally witnessed numerous officials and commoners suffering from this. Therefore, I would rather consume Wild Ge (Yege, a toxic vine) than take Five Minerals Powder, clearly recognizing its immense and fierce toxicity. One must be extremely cautious. Wise individuals encountering this formula should burn it immediately and not keep it. I now record only the indications and contraindications to prevent harm to those who have previously taken it. The formula itself has been destroyed by fire and need no longer be preserved, to avoid harming living beings.