此症多因早年患杨梅毒时，服食轻粉、汞剂过多，欲求速效，致后日发生此种粉霜毒
气，遍身关节疼痛，骨里潮热，气逆则痰不行，遂结成豆子大小之粒，渐渐长大，皮肤不
红，肉内作痛，延至日久，医者多以行痰顺气之剂治之，屡治不效，后遂溃而出水，与棉
絮相似，此刻其痛更甚，初不知其为误服轻粉，毒入骨髓之所致也。治法内服中九丸兼金
蚣丸，再加托里排脓之剂，成脓者可治，不成脓者难治。成脓后，用解毒膏贴之，插药线
三次，俟脓干，取出絮团后，以熏洗汤洗净，再掺加味天然散收功。
此症肉皮赤肿，发泡痛甚，破皮后则排泄清水，痛如针刺，乃热极也。治法宜内服中
九丸、金蚣丸，兼用清热解肌汤及黄连解毒汤，服至三剂后，再加大黄以消利三、五次，
除去邪热，外搽太岁墨止痛，候水分干尽时，掺天然散、贴解毒膏平口，切忌发物。
清热解肌汤
黄芩（八钱） 大连（八钱） 枳壳 栀子 连翘 荆芥 防风 花粉 陈皮
浓朴 猪苓 泽泻 木通 黄柏（各五分） 甘草（二钱） 灯心（为引）
上水煎，连服三剂。
又单方∶
大黄一两，倍子五钱，共研细末，用鸡蛋清调搽患处。
此症因胎中受热，致生此疮，或生两膝眼上，或生肾囊上不定，皮肤赤肿，破皮后则
出血痛甚，水洗至何处，即烂至何处，治方如下∶
铅粉（三钱火 黄色） 乳香 没药 血竭 黄柏（各二两） 轻粉（三钱） 冰片（一分） 白蜡（二钱）
上共为细末，清油调搽，切忌发物。
又方∶
黄柏三钱，猪胆一枚，将胆汁搽于黄柏上炙干，又搽又炙，数次之后，取黄柏为末调搽之。
这种病症多因早年患杨梅毒（梅毒）时，服用轻粉、汞剂过多，急于求速效，导致日后发生此种由粉霜毒气引起的病变。症状表现为遍身关节疼痛，骨中潮热，气机逆乱则痰液停滞不行，于是结成如豆子大小的颗粒，逐渐长大，皮肤不红，但肌肉内部作痛。拖延日久后，医生多以行痰顺气的方剂治疗，屡治无效，随后溃破流出液体，与棉絮相似，此刻疼痛更加剧烈。起初人们并不知道这是误服轻粉、毒邪深入骨髓所致。治疗方法为内服中九丸兼金蚣丸，再加用托里排脓的方剂，若能成脓者尚可治愈，不成脓者难治。成脓后，用解毒膏贴敷患处，插入药线三次，待脓液干涸，取出絮团后，以熏洗汤洗净，再掺加味天然散以收功。
此症表现为肉皮赤肿，发泡且疼痛剧烈，破皮后排泄清水，痛如针刺，这是热极的表现。治疗方法宜内服中九丸、金蚣丸，兼用清热解肌汤及黄连解毒汤，服用至三剂后，再加大黄以消利三到五次，以除去邪热。外搽太岁墨止痛，待水分干尽时，掺天然散、贴解毒膏使创口平复，切忌食用发物。
清热解肌汤：黄芩（八钱）、大连（八钱，注：此处疑为“大连”或特定药材别名，依原文保留）、枳壳、栀子、连翘、荆芥、防风、花粉、陈皮、浓朴、猪苓、泽泻、木通、黄柏（各五分）、甘草（二钱）、灯心（作为药引）。以上用水煎煮，连续服用三剂。
又单方：大黄一两，倍子五钱，共研细末，用鸡蛋清调匀搽于患处。
此症因胎中受热，导致生出此疮，或生于两膝眼上，或生于肾囊上，位置不定。皮肤赤肿，破皮后出血且疼痛剧烈，水洗到哪里，溃烂就蔓延到哪里。治疗方剂如下：铅粉（三钱，火煅至黄色）、乳香、没药、血竭、黄柏（各二两）、轻粉（三钱）、冰片（一分）、白蜡（二钱）。以上共研为细末，用清油调匀搽涂，切忌食用发物。
This condition is mostly caused by excessive consumption of Calomel (Hydrargyri Chloridum Mite) and mercury preparations during early-stage Lues Venereum (Syphilis), seeking rapid efficacy, which subsequently leads to the occurrence of this "powder frost toxicity" syndrome. Symptoms include pain throughout the joints of the body, tidal fever in the bones, and qi rebellion causing phlegm stagnation. Consequently, nodules the size of beans form and gradually enlarge; the skin is not red, but there is pain within the flesh. After a long duration, physicians often treat it with formulas for moving phlegm and regulating qi, but these treatments repeatedly fail. Eventually, the lesions ulcerate and exude fluid resembling cotton wadding, at which point the pain becomes even more severe. Initially, it was unknown that this was caused by the accidental ingestion of Calomel and the penetration of toxicity into the bone marrow. The treatment method involves internal administration of Zhongjiu Wan (Nine-Pill Decoction) combined with Jingsong Wan (Golden Centipede Pill), along with formulas for supporting the interior and expelling pus. Cases where pus forms are curable, while those without pus formation are difficult to treat. After pus formation, apply Jiedu Gao (Detoxification Plaster). Insert medicinal threads three times. Wait for the pus to dry, remove the wadding-like masses, wash clean with Xunxi Tang (Fumigation and Washing Decoction), and finally apply Jiawei Tianran San (Modified Natural Powder) to complete the healing.
This condition presents with reddish swelling of the skin and flesh, blistering with severe pain. Upon rupture, clear fluid is discharged, and the pain feels like needle pricks, indicating extreme heat. The treatment should involve internal administration of Zhongjiu Wan and Jingsong Wan, combined with Qingre Jiemi Tang (Clear Heat and Release Muscle Decoction) and Huanglian Jiedu Tang (Coptis Detoxification Decoction). After taking three doses, add Radix Rheomi Preparata (Dahuang) to promote urination and bowel movement three to five times to eliminate pathogenic heat. Externally, apply Taisui Mo (Tai Sui Ink) to relieve pain. When the moisture has completely dried, sprinkle Tianran San (Natural Powder) and apply Jiedu Gao (Detoxification Plaster) to level the wound surface. Strictly avoid "fa wu" (stimulating foods that may exacerbate disease).
Qingre Jiemi Tang: Huangqin (Scutellariae Radix, 8 qian), Dalian (8 qian, note: likely a specific local herb or alias, retained as per text), Zhike (Aurantii Fructus), Zhizi (Gardeniae Fructus), Lianqiao (Forsythiae Fructus), Jingjie (Schizonepetae Herba), Fangfeng (Saposhnikoviae Radix), Huafen (Trichosanthis Radix), Chenpi (Citri Reticulatae Pericarpium), Nongpo (Magnoliae Officinalis Cortex), Zhuling (Polyporus), Zexie (Alismatis Rhizoma), Mutong (Akebiae Caulis), Huangbai (Phellodendri Cortex, each 5 fen), Gancao (Glycyrrhizae Radix et Rhizoma, 2 qian), Dengxin (Junci Medullia, used as a guiding drug). Decoct in water and take continuously for three doses.
Another single prescription: Dahuang (Radix Rheomi Preparata, 1 liang), Beizi (5 qian, note: specific seed/herb, retained as per text). Grind together into a fine powder, mix with egg white, and apply to the affected area.
This condition arises from heat accumulated in the womb during fetal development, leading to the formation of this sore. It may appear on either knee pit or on the scrotum, with unpredictable location. The skin is reddish and swollen; upon rupture, bleeding occurs with severe pain. Wherever water touches, the ulceration spreads. The treatment formula is as follows: Qianfen (Cerussa, 3 qian, calcined until yellow), Ruxiang (Olibanum), Moyao (Myrrha), Xuexie (Dracaenae Sangue), Huangbai (Phellodendri Cortex, each 2 liang), Qingfen (Calomel, 3 qian), Bingpian (Borneolum Syntheticum, 1 fen), Bala (Cera Flava, 2 qian). Grind all ingredients into a fine powder, mix with refined oil, and apply externally. Strictly avoid stimulating foods.
Another prescription: Huangbai (Phellodendri Cortex, 3 qian), one pig gallbladder. Apply the bile onto the Huangbai and roast it dry. Repeat the process of applying bile and roasting several times. Finally, grind the treated Huangbai into a powder and apply mixed with an appropriate vehicle to the affected area.