夫时气二日。阳明受病。阳明主于肌肉。其脉络于鼻。入于目。故得病二日肉热鼻干。
不得眠也。夫诸阳在表。表始受病。故可摩膏火灸。发汗而愈也。
治时气二日。头痛壮热。宜服水解散方。
麻黄（二两去根节） 川大黄（一两锉碎微炒） 黄芩（一两） 桂心（一两） 甘草
（一两炙
微赤锉） 赤芍药（一两）
上件药。捣细罗为散。每服。不计时候。以温水调下二钱。良久再服。未服药前。先以
热汤淋浴后。便服此药。衣盖取汗。
治时气二日。壮热。头疼。宜服此方。
甘草（一两炙微赤锉） 生姜（三分） 栝蒌（一颗大者取瓤去子于碗内盛之）
上件药。先将生姜甘草。用无灰酒一大盏。煎取六分。去滓。热入栝蒌碗中绞取汁。不
计时候。分温二服。
治时气二日。壮热憎寒。头痛。腰脊强重。宜服柴胡散方。
柴胡（一两去苗） 麻黄（一两去根节） 葛根（三分锉） 桂心（三分） 甘草（一
分炙微赤
锉）
上件药。捣罗为散。每服四钱。以水一中盏。入豉五十粒。薄荷二七叶。煎至六分。去
滓。不计时候。先吃粥少许。后以热水淋浴。然后服此药。衣覆取汗。
治时气二日。头痛。背强。身热恶寒。宜服栀子散方。
栀子仁（一两） 黄芩（一两） 石膏〔一（二）两〕 杏仁（一两汤浸去皮尖双仁麸
炒微黄）
葛根（一两锉） 甘草（半两炙微赤锉）
上件药。捣罗为散。每服五钱。以水一大盏。入葱白二茎。豉五十粒。煎至五分。去滓
。不计时候。热服。衣覆取汗。
治时气二日。头痛。背强。心烦壮热。宜服葛根散方。
葛根（锉） 麻黄（去根节） 犀角屑（以上各一两）
上件药。捣罗为散。每服五钱。以水一大盏。入生姜半分。枣三枚。煎至五分。去滓。
不计时候。热服。衣覆取汗。
时气病发病第二日，邪气传入阳明经。阳明经主管肌肉，其经脉联络鼻部，进入目内。因此患病第二天会出现肌肉发热、鼻干、无法安睡的症状。因为诸阳经位于体表，体表刚开始受邪，所以可以用涂摩药膏、火灸的方法，通过发汗使疾病痊愈。
治疗时气病第二日，出现头痛、高热症状，适宜服用水解散方。
药材：麻黄（二两，去除根和节）、川大黄（一两，锉碎后微炒）、黄芩（一两）、桂心（一两）、甘草（一两，炙至微红并锉碎）、赤芍药（一两）。
制法与用法：将上述药物捣碎过罗成为散剂。每次服用，不限时间，用温水调服二钱。隔一段时间后再次服用。在服药前，先用热水淋浴，然后立即服用此药，并用衣物覆盖身体以取汗。
治疗时气病第二日，出现高热、头痛症状，适宜服用此方。
药材：甘草（一两，炙至微红并锉碎）、生姜（三分）、栝蒌（一颗大的，取瓤去子放在碗内）。
制法与用法：先将生姜和甘草，用无灰酒一大盏，煎煮至剩余六分，滤去药渣。将热药汁倒入盛有栝蒌瓤的碗中，绞取汁液。不限时间，分两次温服。
治疗时气病第二日，出现高热怕冷、头痛、腰脊僵硬沉重症状，适宜服用柴胡散方。
药材：柴胡（一两，去除苗）、麻黄（一两，去除根和节）、葛根（三分，锉碎）、桂心（三分）、甘草（一分，炙至微红并锉碎）。
制法与用法：将上述药物捣碎过罗成为散剂。每次服用四钱，用水一中盏，加入豆豉五十粒、薄荷十四片，煎煮至剩余六分，滤去药渣。不限时间，先吃少许粥，然后用热水淋浴，随后服用此药，覆盖衣物以取汗。
治疗时气病第二日，出现头痛、背部僵硬、身体发热恶寒症状，适宜服用栀子散方。
药材：栀子仁（一两）、黄芩（一两）、石膏（一两或二两）、杏仁（一两，汤浸去皮尖及双仁，麸炒至微黄）、葛根（一两，锉碎）、甘草（半两，炙至微红并锉碎）。
制法与用法：将上述药物捣碎过罗成为散剂。每次服用五钱，用水一大盏，加入葱白两段、豆豉五十粒，煎煮至剩余五分，滤去药渣。不限时间，热服，覆盖衣物以取汗。
治疗时气病第二日，出现头痛、背部僵硬、心烦、高热症状，适宜服用葛根散方。
药材：葛根（锉碎）、麻黄（去除根节）、犀角屑（以上各一两）。
制法与用法：将上述药物捣碎过罗成为散剂。每次服用五钱，用水一大盏，加入生姜半分、大枣三枚，煎煮至剩余五分，滤去药渣。不限时间，热服，覆盖衣物以取汗。
On the second day of a seasonal epidemic disease (Shi Qi Bing), the pathogen affects the Yangming channel. The Yangming channel governs the muscles, its collaterals connect to the nose, and it enters the eyes. Therefore, on the second day of illness, symptoms include muscle heat, dryness of the nose, and insomnia. Since all Yang channels are located at the exterior, and the exterior is just beginning to be affected by the pathogen, treatment can involve applying medicated ointments or moxibustion to induce sweating and achieve recovery.
For the second day of a seasonal epidemic disease, presenting with headache and high fever, the Shuijie San (Water-Resolving Powder) is indicated.
Ingredients: Ephedrae Herba (Mahuang, 麻黄) (2 liang, remove roots and nodes), Rheum Radix et Rhizoma (Chuan Dahuang, 川大黄) (1 liang, cut into small pieces and lightly stir-fried), Scutellariae Radix (Huangqin, 黄芩) (1 liang), Cinnamomi Cortex (Guixin, 桂心) (1 liang), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 liang, honey-fried until slightly red and cut into small pieces), Paeoniae Rubra Radix (Chishaoyao, 赤芍药) (1 liang).
Preparation and Administration: Pulverize the above ingredients through a fine sieve to make a powder. Take 2 qian each time, at any time, mixed with warm water. Administer another dose after some time. Before taking the medicine, take a hot shower first, then immediately take this medicine, and cover the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with high fever and headache, this formula is indicated.
Ingredients: Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 liang, honey-fried until slightly red and cut into small pieces), Zingiberis Rhizoma Recens (Shengjiang, 生姜) (3 fen), Trichosanthis Fructus (Gualou, 栝蒌) (one large fruit, take the pulp, remove seeds, and place in a bowl).
Preparation and Administration: First, decoct the ginger and licorice root in one large cup of unadulterated wine until reduced to six-tenths. Strain the dregs. Pour the hot liquid into the bowl containing the trichosanthis pulp, squeeze to extract the juice. Take divided into two warm doses, at any time.
For the second day of a seasonal epidemic disease, presenting with high fever, aversion to cold, headache, and stiffness/heaviness of the waist and spine, the Chaihu San (Bupleurum Powder) is indicated.
Ingredients: Bupleuri Radix (Chaihu, 柴胡) (1 liang, remove sprouts), Ephedrae Herba (Mahuang, 麻黄) (1 liang, remove roots and nodes), Puerariae Radix (Gegen, 葛根) (3 fen, cut into small pieces), Cinnamomi Cortex (Guixin, 桂心) (3 fen), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (1 fen, honey-fried until slightly red and cut into small pieces).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 4 qian each time. Decoct with one medium cup of water, adding 50 grains of Sojae Preparata (Douchi, 豆豉) and 14 leaves of Menthae Haplocalycis (Bohe, 薄荷), until reduced to six-tenths. Strain the dregs. At any time, eat a little porridge first, then take a hot shower, followed by administering this medicine. Cover the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with headache, back stiffness, body heat, and aversion to cold, the Zhizi San (Gardenia Powder) is indicated.
Ingredients: Gardeniae Fructus (Zhizi Ren, 栀子仁) (1 liang), Scutellariae Radix (Huangqin, 黄芩) (1 liang), Gypsum Fibrosum (Shigao, 石膏) (1 or 2 liang), Pruni Semen Armeniacae Amarum (Xingren, 杏仁) (1 liang, soaked in water, remove skin and tips, discard double-kernel ones, stir-fried with bran until slightly yellow), Puerariae Radix (Gegen, 葛根) (1 liang, cut into small pieces), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草) (0.5 liang, honey-fried until slightly red and cut into small pieces).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 5 qian each time. Decoct with one large cup of water, adding 2 stems of Allii Fistulosi Bulbus (Congbai, 葱白) and 50 grains of Sojae Preparata (Douchi, 豆豉), until reduced to five-tenths. Strain the dregs. Take hot at any time, covering the body with clothing to induce sweating.
For the second day of a seasonal epidemic disease, presenting with headache, back stiffness, mental restlessness, and high fever, the Gegen San (Kudzu Powder) is indicated.
Ingredients: Puerariae Radix (Gegen, 葛根) (cut into small pieces), Ephedrae Herba (Mahuang, 麻黄) (remove roots and nodes), Cornu Bubali (Xijiao, 犀角) (each 1 liang).
Preparation and Administration: Pulverize the above ingredients through a sieve to make a powder. Take 5 qian each time. Decoct with one large cup of water, adding 0.5 fen of Zingiberis Rhizoma Recens (Shengjiang, 生姜) and 3 dates, until reduced to five-tenths. Strain the dregs. Take hot at any time, covering the body with clothing to induce sweating.