夫 疟者。夏伤于暑。其病。秋则寒甚。冬则寒轻。春则恶风。夏则多汗者。然其蓄作
有时。以疟之始发。先起于毫毛。呻欠乃作寒栗鼓颔。腰脊疼痛。寒去则外内皆热。头痛。
如渴
则寒
外皆
于皮
之以
以隔
治 疟。积年不瘥者。宜服知母饮子方。
知母（半两） 鳖甲（一两涂醋炙令黄去裙 ） 恒山（一两锉） 乌梅肉（七枚微炒）
豉心
（一百粒） 粳米（一百粒） 甘草（半两炙微赤锉） 川大黄（半两）
上件药。细锉和匀。每服半两。以童子小便一中盏。浸一宿。五更初煎至六分。去滓温
服。临发前再服。以利为度。每日发与不发。皆得服之。待遇发后。即得吃食。
又方。
恒山（半两锉） 甘草（二两生用） 川大黄（半两） 桂心（半两）
上件药。捣筛为散。每服五钱。以水一中盏。煎至六分。去滓。空腹温服。欲
发前再服。
治 疟久不瘥。虎头骨丸方。
虎头骨（二两涂酥炙微黄） 朱砂（半两细研） 恒山（一两锉） 甘草〔一两（半）
锉生用〕
牡蛎（二
两微
炒） 附子（
两锉碎微
炒） 桃仁（三十枚汤
上件药。捣罗为末。研入朱砂令匀。炼蜜和捣三二百杵。丸如梧桐子大。每于发前。以
桃符汤下十丸。
治 疟。或发或歇久不瘥。乌梅丸方。
乌梅肉（二七枚） 恒山（三两末） 香豉（二两） 桃仁（四十九枚汤浸去皮尖双仁）
上件药。都捣如泥。以少许蜜。和捣二三百许。丸如梧桐子大。每服。以粥饮下三十丸
日三服。
治 疟。连年不瘥。服三七日定瘥。蜀漆丸方。
蜀漆（一两） 乌梅肉（一两微炒） 石膏（二两细研水飞过） 知母〔二（一）两〕 白
薇（
一两） 甘草
升麻（一
两） 葳蕤（
上件药。捣罗为末。炼蜜和捣三二百杵。丸如梧桐子大。每服。以温酒下二十丸。日三
服。
又方。
鲮鲤甲（二七枚炙黄） 鳖甲（一两生用） 乌贼鱼骨（一两） 附子（一分生用去皮
脐）
上件药。细锉。以酒三盏浸一宿。发前。温酒顿饮之。一日断食。
又方。
朱砂（一分细研） 恒山末（三分）
上件药。都研令匀。炼蜜和丸。如绿豆大。于发日平明。以温水下五丸。至夜然后食之
疟疾这种病，是因为夏季感受了暑邪。其病症表现为：秋季时寒战严重，冬季时寒战轻微，春季时怕风，夏季时多汗。然而，疟疾的发作与休止是有定时的。在疟疾刚开始发作时，先感觉毫毛竖立，接着打哈欠，随即出现寒战、鼓颔（下巴颤抖）、腰脊疼痛。当寒战过去后，内外都感到发热，头痛，像口渴一样。
治疗疟疾，如果是积年不愈的，适宜服用知母饮子方。
知母（半两） 鳖甲（一两，涂醋炙至黄色，去除裙边） 恒山（一两，锉碎） 乌梅肉（七枚，微炒） 豉心（一百粒） 粳米（一百粒） 甘草（半两，炙至微红，锉碎） 川大黄（半两）
以上药物，细锉并混合均匀。每次服用半两，用童子小便一中盏，浸泡一夜，五更初煎煮至六分，去渣，温服。在疟疾发作前再服一次。以腹泻为度。无论每日是否发作，都可以服用。等到发作过后，就可以进食。
又一方。
恒山（半两，锉碎） 甘草（二两，生用） 川大黄（半两） 桂心（半两）
以上药物，捣碎筛成散剂。每次服用五钱，用水一中盏，煎煮至六分，去渣。空腹温服。在欲发作前再服一次。
治疗疟疾日久不愈，虎头骨丸方。
虎头骨（二两，涂酥炙至微黄） 朱砂（半两，细研） 恒山（一两，锉碎） 甘草（一两半，锉碎，生用） 牡蛎（二两，微炒） 附子（一两，锉碎，微炒） 桃仁（三十枚，汤浸去皮尖双仁）
以上药物，捣罗成末，加入朱砂研匀。用炼蜜调和，捣三二百杵，制成梧桐子大小的丸药。每次在发作前，用桃符汤送服十丸。
治疗疟疾，或发或歇，日久不愈，乌梅丸方。
乌梅肉（十四枚） 恒山（三两，研末） 香豉（二两） 桃仁（四十九枚，汤浸去皮尖双仁）
以上药物，一起捣如泥状，加少许蜂蜜，和捣二三百下，制成梧桐子大小的丸药。每次服用，用粥饮送服三十丸，每日三次。
治疗疟疾，连年不愈，服用三七日可痊愈，蜀漆丸方。
蜀漆（一两） 乌梅肉（一两，微炒） 石膏（二两，细研水飞） 知母（一两） 白薇（一两） 甘草（一两） 升麻（一两） 葳蕤（一两）
以上药物，捣罗成末，用炼蜜调和，捣三二百杵，制成梧桐子大小的丸药。每次服用，用温酒送服二十丸，每日三次。
又一方。
鲮鲤甲（十四枚，炙黄） 鳖甲（一两，生用） 乌贼鱼骨（一两） 附子（一分，生用，去皮脐）
以上药物，细锉，用酒三盏浸泡一夜。在发作前，用温酒一次性饮下。当日断食一天。
又一方。
朱砂（一分，细研） 恒山末（三分）
以上药物，一起研匀，用炼蜜和丸，如绿豆大小。在发作日的黎明，用温水送服五丸，到了晚上才进食。
Malaria is a disease caused by summer-heat injury in summer. Its symptoms manifest as severe chills in autumn, mild chills in winter, aversion to wind in spring, and excessive sweating in summer. However, the paroxysms of malaria occur at regular intervals. At the onset of a malaria attack, it begins with piloerection (hair standing on end), followed by yawning, then progressing to shivering, trembling of the jaw, and pain in the lower back and spine. After the cold stage passes, both internal and external heat ensues, accompanied by headache and thirst.
For treating malaria that has persisted for years without cure, the Zhi Mu Yin Zi Decoction (Anemarrhenae Drink) is suitable.
Zhi Mu (Anemarrhenae Rhizoma, Ban Liang) Bie Jia (Testudinis Carapax et Plastrum, Yi Liang, vinegar-coated and roasted until yellow, remove skirt) Heng Shan (Dichroae Radix, Yi Liang, chopped) Wu Mei Rou (Mume Fructus Flesh, Qi Mei, lightly roasted) Chi Xin (Sojae Semen Praeparatum Heart, Yi Bai Li) Jing Mi (Oryza Sativa Germen, Yi Bai Li) Gan Cao (Glycyrrhizae Radix et Rhizoma, Ban Liang, roasted until slightly red, chopped) Chuan Da Huang (Rhei Radix et Rhizoma, Ban Liang)
The above herbs are finely chopped and mixed evenly. Take half a liang per dose. Soak overnight in one zhong of urine from an uncircumcised boy. In the early hours of the fifth watch (wugeng), decoct until reduced to six-tenths. Strain and take warm. Administer another dose before the anticipated onset. The treatment should continue until diarrhea occurs. It may be taken daily regardless of whether an attack is occurring. Food can be consumed after the paroxysm subsides.
Another prescription.
Heng Shan (Dichroae Radix, Ban Liang, chopped) Gan Cao (Glycyrrhizae Radix et Rhizoma, Er Liang, raw) Chuan Da Huang (Rhei Radix et Rhizoma, Ban Liang) Gui Xin (Cinnamomi Cortex, Ban Liang)
The above herbs are pounded, sifted into a powder. Take five qian per dose. Decoct in one zhong of water until reduced to six-tenths. Strain and take warm on an empty stomach. Administer another dose before the anticipated onset.
Tiger Head Bone Pill for treating long-standing malaria that does not heal.
Hu Tou Gu (Tigris Ossis Capitis, Er Liang, coated with lard and roasted until slightly yellow) Zhu Sha (Cinnabaris, Ban Liang, finely ground) Heng Shan (Dichroae Radix, Yi Liang, chopped) Gan Cao (Glycyrrhizae Radix et Rhizoma, One and a half liang, chopped, raw) Mu Li (Ostreae Concha, Er Liang, lightly roasted) Fu Zi (Aconiti Lateralis Radix Praeparata, Yi Liang, chopped and lightly roasted) Tao Ren (Persicae Semen, San Shi Mei, soaked in water, skin and pointed ends removed, double-kernel)
The above herbs are pounded and sieved into powder. Mix thoroughly with Zhu Sha. Combine with refined honey and pound three to two hundred times. Form pills the size of paulownia seeds. Take ten pills before each attack, washed down with Tao Fu Tang (Peach Talisman Decoction).
Wu Mei Wan (Mume Pill) for treating malaria that comes and goes, persisting for a long time without cure.
Wu Mei Rou (Mume Fructus Flesh, Er Qi Mei, i.e., fourteen) Heng Shan (Dichroae Radix, San Liang, powdered) Xiang Chi (Sojae Semen Praeparatum, Er Liang) Tao Ren (Persicae Semen, Si Shi Jiu Mei, soaked in water, skin and pointed ends removed, double-kernel)
The above herbs are all pounded into a paste. Add a small amount of honey and pound two to three hundred times. Form pills the size of paulownia seeds. Take thirty pills per dose, washed down with porridge drink. Three times daily.
Shu Qi Wan (Perilae Folium Pill) for treating malaria persisting for years; taking it for twenty-seven days will resolve the condition.
Shu Qi (Perillae Folium, Yi Liang) Wu Mei Rou (Mume Fructus Flesh, Yi Liang, lightly roasted) Shi Gao (Gypsum Fibrosum, Er Liang, finely ground and water-washed) Zhi Mu (Anemarrhenae Rhizoma, Yi Liang) Bai Wei (Cynanchi Atrati Radix, Yi Liang) Gan Cao (Glycyrrhizae Radix et Rhizoma, Yi Liang) Sheng Ma (Cimicifugae Rhizoma, Yi Liang) Wei Rui (Polygonati Odorati Rhizoma, Yi Liang)
The above herbs are pounded and sieved into powder. Combine with refined honey and pound three to two hundred times. Form pills the size of paulownia seeds. Take twenty pills per dose, washed down with warm wine. Three times daily.
Another prescription.
Ling Li Jia (Manis Squama, Er Qi Mei, i.e., fourteen, roasted until yellow) Bie Jia (Testudinis Carapax et Plastrum, Yi Liang, raw) Wu Zei Yu Gu (Sepiae Endoconcha, Yi Liang) Fu Zi (Aconiti Lateralis Radix Praeparata, Yi Fen, raw, skin and navel removed)
The above herbs are finely chopped. Soak in three zhong of wine overnight. Before the attack, drink the wine in one go. Fasting is required for one day.
Another prescription.
Zhu Sha (Cinnabaris, Yi Fen, finely ground) Heng Shan Mo (Dichroae Radix Powder, San Fen)
The above ingredients are ground together until uniform. Combine with refined honey to form pills the size of mung beans. On the day of the attack, at dawn, take five pills washed down with warm water. Do not eat until nightfall.