见所公弱冠，随尊君大司马印老治河居北。患白浊，精淫淫下。自北地山东、淮扬、镇江及
江右三吴诸名家，医药三年不效。癸酉冬，礼予诊之。其脉两寸短弱，两关滑，两尺洪滑，
观其人襟期潇洒出尘，而神色闲雅，真翩翩佳公子也。一接见，便就昵而信余请药。予曰∶
公疾易愈，第待来春之仲，一剂可瘳，而今时不可。公固请曰∶先生大方，而善拯人之急。
以大方而治小疾，试可立效，何待来年？予曰∶非秘其术不售也。《素问》有云∶升降浮沉
必顺之。又曰∶天时不可伐。公脉为湿痰下流症也。经曰∶治痰必先理气。而脉书亦谓，洪
大而见于尺部者，阳乘于阴也。法当从阴引阳，今冬令为闭藏之候，冬之闭藏，实为来春发生
根本，天人一理。若罔顾天时而强用升提之法，是逆天时而泄元气，根本既竭，来春何以发
生？故《素问》曰，必先岁气，毋伐天和，必养必和，待其来复。公疾本小，而历治三年不
效者，良由诸医不知脉、不识病、不按时也。公闻言唯唯。乃尊君所遣之医踵接，治竟无
效，至春分而逆予，以白螺蛳壳火 四两为君，牡蛎二两为臣，半夏、葛根、柴胡、苦参各一
两为佐，黄柏一两为使，面糊为丸，名曰端本丸。令早晚服之，不终剂而全愈。公复书曰∶
贱疾果如先生言，今勿药也，何历治三年不效。窃谓天下无药，服端本丸而愈，又信天下有
药矣。
见所公在二十岁左右时，跟随他的父亲大司马印老治理黄河，居住在北方。他患上了白浊病，精液不由自主地滑出。从北方的山东、淮扬、镇江以及江西和江南三吴地区的各位名医那里，治疗了三年都没有效果。癸酉年冬天，我（孙一奎）为他诊脉。他的两寸脉短弱，两关脉滑，两尺脉洪滑。观察他的仪态，风度潇洒超脱尘俗，神色闲静优雅，真是一位翩翩佳公子。刚一见面，他就亲近信任我，请我开药。我说：“您的病容易治愈，只需等到明年仲春时节，服一剂药即可痊愈，但现在这个季节不行。”见所公坚持请求说：“先生擅长使用大方剂，善于解救他人的急难。用大方剂来治疗小病，尝试一下应该能立即见效，为什么要等到来年呢？”我说：“这并不是我保密医术不卖给您。《素问》中说：升降浮沉必须顺应天时规律。又说：不可违背天时。您的脉象属于湿痰下流的证候。医经说：治疗痰饮必须先调理气机。脉书也认为，洪大的脉象出现在尺部，是阳气乘袭阴分所致。治疗方法应当从阴引阳。现在正值冬季，是闭藏的时令，冬季的闭藏实际上是来年春季万物生发的根本，天与人的道理是一致的。如果无视天时强行使用升提的方法，就是违背天时而耗泄元气，根本既然枯竭，来年如何生发？所以《素问》说：必须首先了解当年的气候特点，不要伤害人体的自然和谐之气，必须养护调和，等待其恢复。您的病本来轻微，但经过三年治疗无效，确实是因为各位医生不懂脉理、不认识病症、不顺应时令的缘故。”见所公听了连连点头称是。他父亲派来的医生接踵而至，治疗最终都无效。到了春分时节，我采用逆治法，以四两煅烧过的白螺蛳壳为君药，二两牡蛎为臣药，半夏、葛根、柴胡、苦参各一两为佐药，黄柏一两为使药，用面糊制成丸剂，命名为“端本丸”。让他早晚服用，还没服完一剂就完全痊愈了。见所公回信说：“我的病果然像先生所说的那样，现在已经不用吃药了，为什么之前治疗三年无效呢？我私下认为，天下没有药可治，吃了端本丸却好了；我又相信天下是有药可治的了。”
When Master Jiansuo was in his early twenties, he accompanied his father, Grand Marshal Yin Lao, to manage the Yellow River and resided in the north. He suffered from *bai zhuo* (white turbid discharge, often referring to spermatorrhea or leukorrhea), with semen flowing out incessantly. For three years, he sought treatment from various renowned physicians in Shandong, Huaiyang, Zhenjiang, Jiangxi, and the Sanwu region of Jiangnan, but without effect. In the winter of the Guiyou year, I examined him. His pulse at both cun positions was short and weak; at both guan positions, it was slippery; and at both chi positions, it was surging and slippery. Observing his demeanor, he was elegant and detached from worldly cares, with a calm and refined expression, truly a graceful young gentleman. Upon our first meeting, he readily trusted me and requested my prescription. I said, "Your illness is easy to cure. However, you must wait until mid-spring next year. One dose will suffice, but not now." Master Jiansuo insisted, saying, "Sir is adept at using large prescriptions and excels at relieving urgent distress. Using a major formula for a minor ailment should yield immediate results. Why wait until next year?" I replied, "This is not because I am withholding my technique. The *Suwen* states: 'Ascending, descending, floating, and sinking must accord with the laws of nature.' It also says: 'Do not violate the timing of heaven.' Your pulse indicates a syndrome of damp-phlegm flowing downward. The classics state: 'To treat phlegm, one must first regulate qi.' Pulse texts also teach that a surging pulse appearing at the chi position indicates yang invading yin. The method should be to draw yang from yin. Winter is the season of closure and storage; this winter storage is actually the root for the sprouting of spring. Heaven and humanity follow the same principle. If one ignores the seasonal timing and forcibly uses ascending methods, it violates heaven's timing and depletes primordial qi. Once the root is exhausted, how can there be growth in spring? Therefore, the *Suwen* says: 'First understand the annual climate, do not harm the harmony of heaven and human nature; nourish and harmonize, and wait for recovery.' Your illness is minor, yet ineffective treatment for three years is due to physicians' ignorance of pulse diagnosis, disease identification, and seasonal timing." Master Jiansuo agreed. Physicians sent by his father continued to treat him without success. At the time of the Spring Equinox, I employed a counter-treatment method. I used four liang of calcined *Bianluoqi* (White Conch Shell) as the sovereign herb, two liang of *Muli* (Oyster Shell) as the minister herb, one liang each of *Banxia* (Pinellia Rhizome), *Gegen* (Pueraria Root), *Chaihu* (Bupleurum Root), and *Kushen* (Sophora Root) as the assistant herbs, and one liang of *Huangbai* (Phellodendron Bark) as the guide herb. These were made into pills using flour paste, named *Duanben Wan* (Root-Ending Pill). He took them morning and evening and was fully cured before finishing one dose. He wrote back: "My illness indeed healed as Sir predicted, and I no longer need medicine. Why did previous treatments fail for three years? I once thought there was no effective medicine in the world, but after taking Duanben Wan and recovering, I now believe there is medicine in the world."