经云∶诸寒为痛。又云∶痛则为实，内快外痛，为外实内虚，外快内痛，为内实外虚。今痘疮身痛者，是皮
肤浓，肉理密，或为外寒相搏，或热毒内作，或血虚不能荣养，宜审而治之。沧洲翁云∶凡疮发身痛，不
为外寒所折，则肉腠浓密，
宜分而治之。若红点方见，为寒所折，而内体有热，宜木香参苏饮，轻者消毒饮，或葛根升麻加芍药汤。肉腠密者，
宜活血散合匀气散。外寒搏者，必兼有表证，如和解汤、攻毒散去柴胡、前胡，皆可用。若兼发热头痛、恶寒
咳嗽者，参苏饮主之。热毒内作血瘀而痛者，先用活命饮（疮疡），次用消毒救苦汤（痘大法）。血虚而瘀，因作痛者，
四物汤之类。遍身如啮，色黑者，毒瓦斯壅滞而血凝也，乃是危证，若二便秘结、喘急烦躁，用栀子仁汤，或猪尾膏
血调片脑治之。自利不食者，不治。
消毒饮
牛蒡子（三钱，炒） 荆芥（一钱） 甘草（半钱，生用） 防风（去芦，半钱）
上细切。作一服，水煎。加生犀角尤妙。
葛根升麻加芍药汤（升麻葛根汤、倍芍药是也）
活血散（出不快）
匀气散 （即《济生方》八味顺气散、加木香也）
白术 白茯苓 青皮 白芷 陈皮 乌药 人参（各五钱） 甘草（炙，二分半） 木香（一分半）
上细切。作一服，水一盏，煎七分服。或细末，酒调亦可。
《黄帝内经》说：各种寒邪会导致疼痛。又说：疼痛属于实证，如果体表感觉舒适而体内疼痛，这是外实内虚；如果体表疼痛而体内感觉舒适，这是内实外虚。如今痘疮患者出现全身疼痛，是因为皮肤致密、肌肉纹理紧密，或者是由于外感寒邪与正气相搏结，或者是热毒在体内发作，或者是血虚不能濡养肌肤所致，应当仔细辨证后进行治疗。沧洲翁说：凡是痘疮发出时伴有身体疼痛，如果不是因为外寒遏制了阳气，就是由于肉腠致密，应当分别情况治疗。如果红点刚刚出现，是被寒邪所遏制，而体内有热，适宜用木香参苏饮，病情轻的可用消毒饮，或者葛根升麻加芍药汤。如果是肉腠致密的，适宜用活血散配合匀气散。如果是外寒相搏的，必定兼有表证，如和解汤、攻毒散去柴胡和前胡，都可以使用。如果兼有发热、头痛、恶寒、咳嗽等症状，以参苏饮为主治方。如果是热毒在体内发作导致血瘀而疼痛的，先用活命饮（用于疮疡），再用消毒救苦汤（治疗痘疹的大法）。如果是血虚且伴有瘀滞因而疼痛的，用四物汤之类的方剂。如果全身像被虫咬一样疼痛，且颜色发黑，这是毒气壅滞导致血液凝结，属于危重证候，如果同时伴有大小便不通畅、气喘急促、烦躁不安，用栀子仁汤，或者用猪尾膏调和片脑（冰片）治疗。如果自发性腹泻且不能进食的，属于不治之症。
消毒饮
牛蒡子（三钱，炒制） 荆芥（一钱） 甘草（半钱，生用） 防风（去芦头，半钱）
以上药材切碎。作为一服量，加水煎煮。加入生犀角效果更佳。
葛根升麻加芍药汤（即升麻葛根汤，芍药用量加倍）
活血散（用于痘出不快）
匀气散（即《济生方》中的八味顺气散，加上木香）
白术 白茯苓 青皮 白芷 陈皮 乌药 人参（各五钱） 甘草（炙，二分半） 木香（一分半）
以上药材切碎。作为一服量，用水一盏，煎至七分，服用。也可以研成细末，用酒调服。
The *Yellow Emperor's Inner Classic* states: "All pains caused by cold." It also states: "Pain indicates excess. If the exterior feels comfortable but the interior is painful, it is exterior excess and interior deficiency; if the exterior is painful but the interior feels comfortable, it is interior excess and exterior deficiency." Now, regarding body pain in smallpox (variola), this occurs because the skin is dense and the muscle texture is tight, or due to external cold battling with the pathogen, or internal heat-toxin arising, or blood deficiency failing to nourish and moisten. One must examine carefully and treat accordingly. Master Cangzhou said: "Whenever sores erupt accompanied by body pain, if not suppressed by external cold, then the flesh and pores are dense and tight; one should differentiate and treat accordingly." If red spots are just appearing, suppressed by cold, while the internal constitution has heat, Muxiang Shen Su Yin (Wood-Aromatic Ginseng & Perilla Decoction) is suitable; for mild cases, Xiaodu Yin (Detoxification Decoction) or Gegen Shengma Jia Shaoyao Tang (Pueraria & Cimicifuga Decoction with Added Peony Root) may be used. For those with dense flesh and pores, Huoxue San (Blood-Invigorating Powder) combined with Yunqi San (Qi-Balancing Powder) is appropriate. For external cold battle, there must necessarily be exterior syndrome symptoms; as such, Hejie Tang (Harmonizing Decoction) or Gongdu San (Toxin-Attacking Powder, excluding Chaihu and Qianhu) can all be used. If accompanied by fever, headache, aversion to cold, and cough, Shen Su Yin (Ginseng & Perilla Decoction) is the primary formula. If pain is caused by internal heat-toxin arising and blood stasis, first use Huoming Yin (Life-Saving Decoction, indicated for carbuncles and sores), followed by Xiaodu Jiuku Tang (Detoxification & Suffering-Relief Decoction, a major method for treating smallpox). If pain arises from blood deficiency with stasis, formulas similar to Siwu Tang (Four Substances Decoction) are used. If the whole body feels like being bitten, with black discoloration, this indicates toxic qi stagnation and blood coagulation, which is a critical condition. If accompanied by constipation of both bowels, rapid breathing, and irritability, Zhizi Ren Tang (Gardenia Seed Decoction) or Zhuwei Gao (Pig Tail Paste) mixed with Pian Nao (Borneol) should be used. If spontaneous diarrhea and an inability to eat occur, it is incurable.
Xiaodu Yin (Detoxification Decoction)
Niu Bang Zi (Arctii Fructus, 3 qian, stir-fried) Jing Jie (Schizonepetae Herba, 1 qian) Gan Cao (Glycyrrhizae Radix et Rhizoma, 0.5 qian, raw) Fang Feng (Saposhnikoviae Radix, de-rhizome, 0.5 qian)
Finely cut. Prepare as one dose, decoct in water. Adding fresh Xi Jiao (Rhinocerotis Cornu) is especially excellent.
Gegen Shengma Jia Shaoyao Tang (Pueraria & Cimicifuga Decoction with Added Peony Root) [Also known as Shengma Gegen Tang, with doubled Shaoyao]
Huoxue San (Blood-Invigorating Powder) [Indicated for slow eruption of sores]
Yunqi San (Qi-Balancing Powder) [This is Ba Wei Shun Qi San from *Jisheng Fang*, plus Mu Xiang]
Bai Zhu (Atractylodis Macrocephalae Rhizoma) Bai Fu Ling (Poria) Qing Pi (Citri Reticulatae Pericarpium Viride) Bai Zhi (Angelicae Dahuricae Radix) Chen Pi (Citri Reticulatae Pericarpium) Wu Yao (Linderae Radix) Ren Shen (Ginseng Radix et Rhizoma) [Each 5 qian] Gan Cao (Glycyrrhizae Radix et Rhizoma, honey-fried, 0.25 fen) Mu Xiang (Aucklandiae Radix, 0.15 fen)
Finely cut. Prepare as one dose, decoct in one zhen of water until reduced to 0.7 zhen, then take orally. Alternatively, grind into fine powder and mix with wine.