一、疹子出没，常以六时为准。假如子后出，午后即收，午后出，子后即收，乃阳生阴成，阴
生阳成，造化自然之数也。凡此旋出旋收者轻。若一出连绵三四日不收者，乃阳毒太甚，宜大青汤
，或用荆芥、牛蒡子、甘草、玄参、石膏、桔梗主之。若逡巡不出者，乃风寒外束，皮肤闭密也，
宜荆防败毒散主之。
一、疹已出而复没者，乃风寒所逼而然，若不早治，毒必内攻，以致痒 而死。急用升麻汤加
荆芥、牛蒡子、甘草热服，则疹必复出而安矣。
一、发热六七日以后，明是疹子却不见出，此必皮肤坚浓，腠理闭密，或为风寒所袭，或曾有
吐泻，皆能伏也。急用托里散表之剂，如麻黄汤去杏仁，加蝉蜕、升麻，外用胡荽酒之类。如一向
未更衣者，必毒甚于内，伏而不出《局方》凉膈散加牛蒡子主之。
一、疹子只怕不能得出，若出尽则毒便解。故治疹者，于发热之时，当察时令寒暄，酌而治之
。如时证大寒，以桂枝葛根汤，或麻黄汤发之。时证大热，以升麻葛根汤，或合人参白虎汤发之。
不寒不热，以荆防败毒
散发之。如兼疫疠之气，以人参败毒散发之。如尽一剂，不出，再作本汤服之，外用胡荽酒，又以
苎麻蘸酒遍身戛之，务令亟出。如三四作更不出，加腹中胀痛，气喘昏闷，则死证也。
景岳曰∶按此万氏之法，极得随时制宜之善，已尽发表之义矣。然发表之义，亦最不易，即如
营卫不足而疹有不能出者，其证甚多，若徒知发之，而不知滋之，则营卫有弱者，非惟不能发，而
且恐穷其源矣。此其或在脾胃，或在血气，必得其神，庶乎有济。如伤寒三表之法，实亦有关于此
。
一、疹毒出尽，则邪气解散，正气自然和平。如发热烦闷，或呕吐，或泄泻，此毒邪壅遏，尚
未出尽也。烦热者，黄连解毒汤。呕泄者，柴胡橘皮汤。并外用胡荽酒，及苎麻戛法如前。待疹子
出尽，则烦热自去，呕吐自止矣。
一、疹有既收而余毒未尽，至三日之外又复发出，或至五六次不已者，此因发热之时，不避风
寒，致令邪气郁于肌肉之间，留连不散，虽曾解散，终属未畅耳。若兼杂证，亦当随证治之。
一、疹子的出现与消退，通常以十二时辰为准则。假如在子时之后出疹，午后就会消退；若在午后出疹，子时之后就会消退，这是阳气生发则阴气成就、阴气生发则阳气成就，是自然界造化的自然规律。凡是这种刚出即退的病情较轻。如果一出疹就连绵三四天不退，这是阳热毒邪太盛，适宜用大青汤，或者用荆芥、牛蒡子、甘草、玄参、石膏、桔梗为主药治疗。如果疹子迟疑不出，这是风寒束缚体表，皮肤腠理密闭所致，适宜用荆防败毒散主治。
一、疹子已经发出却又隐没回去的，是被风寒逼迫所致，如果不及时救治，毒邪必然内攻，导致瘙痒而死。急需使用升麻汤加入荆芥、牛蒡子、甘草，趁热服用，那么疹子必定会再次发出而痊愈。
一、发热六七天以后，明明应该是疹子却不见发出，这一定是因为皮肤厚实致密，腠理闭塞，或者是被风寒侵袭，或者曾经有过呕吐腹泻，都能导致疹毒伏留。急需使用托里透表的方剂，比如麻黄汤去掉杏仁，加入蝉蜕、升麻，外用胡荽酒之类。如果一直未解大便，说明体内毒邪极重，伏匿不出，可用《局方》中的凉膈散加入牛蒡子主治。
一、疹子只怕不能透发出来，如果出尽了，毒邪也就解除了。所以治疗疹病的人，在发热的时候，应当观察时令的寒暖，斟酌后进行治疗。如果时令证候属大寒，用桂枝葛根汤，或麻黄汤发散它。如果时令证候属大热，用升麻葛根汤，或合用人参白虎汤发散它。不寒不热，用荆防败毒散发散它。如果兼有疫疠之气，用人参败毒散发散它。如果服完一剂药，疹子还没出，再煎本汤服用，外用胡荽酒，又用苎麻蘸酒遍身擦刮，务必令其迅速透出。如果反复三四次仍不出，加上腹部胀痛，气喘昏闷，就是死证了。
张景岳说：按照万全（万氏）的方法，极得随时制宜的好处，已经尽到了发表的含义。然而发表这一义理，也是最不容易掌握的，就像营卫不足而导致疹子不能发出的情况，证候很多，如果只知道发散，而不知道滋补，那么营卫虚弱的人，不仅不能发散，恐怕还会耗竭其本源。这其中的关键或在脾胃，或在血气，必须得其神妙之处，才可能有疗效。像伤寒中三种表法，其实也与这里有关联。
一、疹毒出尽，则邪气解散，正气自然平和。如果出现发热烦闷，或呕吐，或泄泻，这是毒邪壅滞遏阻，尚未出尽的表现。烦热的，用黄连解毒汤。呕吐泄泻的，用柴胡橘皮汤。并外用胡荽酒，以及苎麻擦刮的方法如前所述。等到疹子出尽，烦热自然去除，呕吐自然停止。
一、疹子虽然已经消退但余毒未尽，到三天之外又重新发出，或者至五六次不止的，这是因为在发热的时候，没有避开风寒，致使邪气郁结在肌肉之间，留连不散，虽然曾经解散过，终究属于不畅通。如果兼杂其他证候，也应当随证治疗。
1. The emergence and disappearance of rashes are usually measured by the twelve two-hour periods (Shichen). If rashes appear after the Zi hour (11:00 PM–1:00 AM), they will recede by Wu hour (11:00 AM–1:00 PM); if they appear at Wu hour, they will recede after Zi hour. This represents the natural law of creation where Yang generates and Yin completes, or Yin generates and Yang completes. Cases where rashes emerge and quickly recede are mild. However, if rashes persist continuously for three to four days without receding, it indicates excessive Yang pathogenic heat/toxin; Da Qing Tang (Great Blue Decoction) should be used, or a prescription primarily composed of Jingjie (Schizonepetae Spica), Niubangzi (Arctii Fructus), Gancao (Glycyrrhizae Radix et Rhizoma), Xuanshen (Scrophulariae Radix), Shigao (Gypsum Fibrosum), and Jiegeng (Platycodonis Radix). If rashes hesitate to emerge, it is due to Wind-Cold constraining the exterior and closing the skin pores (Couli); Jingfang Baidu San (Schizonepeta and Saposhnikovia Powder to Overcome Toxicity) is indicated.
2. When rashes have emerged but then disappear again, it is caused by being forced inward by Wind-Cold. If not treated promptly, the toxin will attack internally, leading to death from itching. Urgently administer Shengma Tang (Cimicifugae Decoction) with added Jingjie, Niubangzi, and Gancao, taken hot; this will cause the rashes to re-emerge and ensure recovery.
3. After six or seven days of fever, if rashes clearly should be present but do not appear, it is likely due to thick and dense skin with closed pores, or invasion by Wind-Cold, or previous vomiting and diarrhea, all of which can cause the toxin to lie latent. Urgently use formulas that support the interior and release the exterior, such as Mahuang Tang (Ephedra Decoction) with Xingren (Prunus Seed) removed, plus Chantui (Cicada Slough) and Shengma, applied externally with Huisu Jiu (Coriander Wine). If there has been no bowel movement for some time, the internal toxin is severe and lying latent; Liangge San (Cooling the Chest Powder) from Ju Fang (Formulas of the Bureau), with added Niubangzi, is indicated.
4. The only concern with rashes is their failure to erupt; once fully erupted, the toxin is resolved. Therefore, when treating rashes during fever, one must observe the seasonal climate (cold or warm) and treat accordingly. In cases of severe cold patterns, Guizhi Gegen Tang (Cinnamon Twig and Pueraria Decoction) or Mahuang Tang should be used to release the exterior. In cases of severe heat patterns, Shengma Gegen Tang (Cimicifuga and Pueraria Decoction) or a combination with Renshen Baihu Tang (Ginseng White Tiger Decoction) should be used. For patterns neither cold nor hot, Jingfang Baidu San should be used. If epidemic Qi is involved, Renshen Baidu San (Ginseng Powder to Overcome Toxicity) should be used. If one dose fails to produce eruptions, another dose of the same decoction should be taken, along with external application of Huisu Jiu and rubbing the entire body with Ramie fiber dipped in wine, striving to force rapid eruption. If after three or four attempts the rash still does not appear, accompanied by abdominal distension and pain, asthma, and drowsiness/confusion, it is a fatal sign.
Zhang Jingyue stated: Regarding Wan Quan’s method, it excellently embodies the principle of adapting to circumstances and seasons, fully realizing the meaning of releasing the exterior. However, the art of releasing the exterior is most difficult. For instance, when Ying and Wei deficiency prevents rashes from emerging, there are many such patterns. If one only knows how to release the exterior without nourishing, those with weak Ying and Wei will not only fail to erupt but may also exhaust their root source. The key lies either in the Spleen and Stomach or in Blood and Qi; one must grasp the subtlety to achieve benefit. The three methods of releasing the exterior in Shanghan (Cold Damage) are indeed relevant here.
5. Once the rash toxin is fully erupted, the pathogenic qi dissipates, and the healthy qi naturally returns to harmony. Symptoms such as fever with restlessness and oppression, vomiting, or diarrhea indicate that the toxin is obstructed and has not yet fully erupted. For restlessness and heat, Huanglian Jiedu Tang (Coptis Decoction to Resolve Toxicity) is used. For vomiting and diarrhea, Chaihu Jupi Tang (Bupleurum and Tangerine Peel Decoction) is used. External applications of Huisu Jiu and the Ramie rubbing method should be employed as before. Once the rashes are fully erupted, the restlessness and heat will naturally subside, and vomiting will cease.
6. If rashes have receded but residual toxin remains, causing them to reappear after three days, or recurring five or six times without stopping, it is because Wind-Cold was not avoided during the fever, causing pathogenic qi to stagnate between the muscles and linger without dispersing. Although previously dispersed, the condition remains unsmooth. If complicated by other syndromes, treatment should follow the specific symptoms.