上药一百二十种为君主养命以应天无毒多服久服不伤人欲轻身益气不老延年者本上经中
药一百二十种为臣主养性以应人无毒有毒斟酌其宜欲遏病补虚羸者本中经下药一百二十五种
为佐使主治病以应地多毒不可久服欲除寒热邪气破积聚愈疾者本下经三品合三百六十五种法
三百六十五度一度应一日以成一岁药有君臣佐使以相宣摄合和宜用一君二臣三佐五使又可一
君三臣九佐使也药有阴阳配合子母兄弟根茎花实草石骨肉有单行者有相须者有相使者有相畏
者有相恶者有相反者有相杀者凡此七情合和视之当用相须相使者良勿用相恶相反者若有毒宜
制可用相畏相杀者不尔勿合用也药有酸咸甘苦辛五味又有寒热温凉四气及有毒无毒阴干曝干
采造时月生熟土地所出真伪陈新并各有法药性有宜丸者宜散者宜水煮者宜酒渍者宜膏煎者亦
有一物兼宜者亦有不可入汤酒者并随药性不得违越欲疗病先察其源先候病机五脏未虚六腑未
竭血脉未乱精神未散服药必活若病已成可得半愈病势已过命将难全若用毒药疗病先起如黍粟
病去即止不去倍之不去十之取去为度疗寒以热药疗热以寒药饮食不消以吐下药鬼疰蛊毒以毒
药痈肿疮瘤以疮药风湿以风湿药各随其所宜病在胸膈以上者先食后服药病在心腹以下者先服
药而后食病在四肢血脉者宜空服而在旦病在骨髓者宜饱满而在夜夫大病之主有中风伤寒寒热
温疟中恶霍乱大腹水肿肠 下痢大小便不通贲豚上气咳逆呕吐黄胆消渴留饮癖食坚积症瘕
惊邪癫痫鬼疰喉痹齿痛耳聋目盲金疮 折痈肿恶疮痔 瘿瘤男子五劳七伤虚乏羸瘦女子带下
崩中
上药一百二十种,作为君药,主要保养生命以顺应天道。这类药物无毒,多服、久服不会伤害人体。想要身体轻健、益气延年、不老的人,应当依据《神农本草经》的上经来选用。
中药一百二十种,作为臣药,主要调养性情以顺应人道。这类药物有的无毒,有的有毒,需要斟酌其适宜性使用。想要遏制疾病、补益虚弱消瘦体质的人,应当依据《神农本草经》的中经来选用。
下药一百二十五种,作为佐使药,主要治疗疾病以顺应地道。这类药物大多有毒,不可长期服用。想要去除寒热邪气、破除积聚、治愈疾病的人,应当依据《神农本草经》的下经来选用。
这三品合起来共三百六十五种药物,对应一年三百六十五天,每一天对应一种药性,从而构成一岁。
药物有君、臣、佐、使的配伍关系,以相互宣通摄纳,调和配合。适宜的使用法度是一君二臣三佐五使,也可以是一君三臣九佐使。
药物有阴阳的配合,以及子、母、兄、弟的关系,包括根、茎、花、实、草、石、骨、肉等不同部位。
药物之间有不同的相互作用:有单独发挥作用的(单行),有互相增强疗效的(相须),有互相辅助的(相使),有互相畏惧制约的(相畏),有互相厌恶减效的(相恶),有互相冲突对抗的(相反),有互相消除毒性的(相杀)。
以上这七种情态关系,在调和使用时,应当选择相须、相使的组合,这样药效良好;不要使用相恶、相反的组合。如果有毒的药物需要炮制处理,可以使用相畏、相杀的药物来制约它;否则不要混合使用。
药物有酸、咸、甘、苦、辛五味,又有寒、热、温、凉四气,以及有毒、无毒的区别。此外,还有阴干、曝晒干燥,采集和制作的时节,生用或熟用,产地来源,真伪新旧等,各有相应的规范。
药性有适宜制成丸剂的,有适宜制成散剂的,有适宜水煮的,有适宜酒浸的,有适宜熬膏煎制的。也有一种药物兼有多种适宜剂型的,也有不适合入汤剂或酒剂的,都要根据药性来决定,不得违背。
想要治疗疾病,首先要考察病因源头,其次要审察病机。如果五脏尚未虚损,六腑尚未衰竭,血脉尚未紊乱,精神尚未耗散,服药后必定能痊愈。如果疾病已经形成,只能获得一半的疗效;如果病势已经过去,生命将难以保全。
如果使用毒药治疗疾病,开始时剂量如黍粟般微小,病去即停药;如果病未去,加倍剂量;再不去,增至十倍,以病除为限度。
治疗寒证用热性药,治疗热证用寒性药,饮食不消化用催吐或泻下药,鬼疰蛊毒用毒药,痈肿疮瘤用外科疮药,风湿用祛风湿药,各随其所宜。
病位在胸膈以上的,先吃饭后服药;病位在心腹以下的,先服药后吃饭;病位在四肢血脉的,宜空腹并在早晨服用;病位在骨髓的,宜饱腹并在夜间服用。
大病的主要病症包括:中风、伤寒、寒热往来、温疟、中恶、霍乱、大腹水肿、肠澼下痢、大小便不通、奔豚、上气、咳逆、呕吐、黄疸、消渴、留饮、癖食、坚积、症瘕、惊邪、癫痫、鬼疰、喉痹、齿痛、耳聋、目盲、金疮、骨折、痈肿、恶疮、痔疾、瘿瘤。
The 120 superior drugs serve as the sovereign (Jun, Monarch) agents to nourish life and correspond to Heaven. They are non-toxic; frequent and long-term use does not harm the human body. Those who desire a light body, increased Qi, longevity, and prevention of aging should base their selection on the Superior Class of the *Shennong Bencao Jing* (Divine Farmer's Materia Medica).
The 120 medium drugs serve as the minister (Chen, Deputy) agents to nourish nature and correspond to Humanity. Some are non-toxic, while others are toxic; their suitability must be carefully considered. Those who wish to suppress disease and tonify deficiency and emaciation should base their selection on the Medium Class of the *Shennong Bencao Jing*.
The 125 inferior drugs serve as the assistant (Zuo, Shi, Envoy) agents to treat disease and correspond to Earth. They are mostly toxic and should not be used for long periods. Those who wish to eliminate cold-heat pathogenic factors, break up accumulations, and cure diseases should base their selection on the Inferior Class of the *Shennong Bencao Jing*.
These three classes total 365 types of drugs, corresponding to the 365 days of a year, with each day representing one drug property, thereby completing a yearly cycle.
Drugs possess sovereign, minister, assistant, and envoy relationships to mutually promote and regulate, harmonizing and combining them. The appropriate dosage structure is one sovereign, two ministers, three assistants, and five envoys; alternatively, it may be one sovereign, three ministers, and nine assistants/envoys.
Drugs have Yin-Yang combinations and relationships of son, mother, brother, and sister, encompassing roots, stems, flowers, fruits/seeds, herbs, minerals, bones, and flesh.
There are seven types of drug interactions: independent action (Dan Xing), mutual enhancement (Xiang Xu), mutual assistance (Xiang Shi), mutual fear/restriction (Xiang Wei), mutual aversion/inhibition (Xiang E), mutual opposition/conflict (Xiang Fan), and mutual detoxification/destruction (Xiang Sha).
Regarding these seven emotional/interactive states, when harmonizing for use, one should prefer combinations of mutual enhancement and mutual assistance, as they yield good results. One should avoid combinations of mutual aversion and mutual opposition. If toxic drugs require processing, one may use drugs that induce mutual fear or mutual detoxification to control them; otherwise, do not combine them.
Drugs possess the Five Flavors (Sour, Salty, Sweet, Bitter, Pungent) and the Four Qi (Cold, Hot, Warm, Cool), as well as distinctions between toxic and non-toxic. Furthermore, there are specific methods for drying in shade or sun-drying, timing of collection and preparation, raw versus cooked usage, geographical origin, authenticity, and age (old vs. new), all governed by distinct rules.
Drug properties dictate suitable formulations: some are suitable for pills (Wan), some for powders (San), some for water decoctions (Shui Zhu), some for wine maceration (Jiu Zi), and some for paste/concentrate preparation (Gao Jian). Some drugs suit multiple forms, while others are unsuitable for decoctions or wines. All decisions must follow drug properties without deviation.
To treat disease, one must first investigate the source of the pathology and then examine the disease mechanism. If the Five Zang organs are not yet deficient, the Six Fu organs are not yet exhausted, the blood vessels are not yet disordered, and the spirit has not yet scattered, medication will surely result in recovery. If the disease has already formed, only half recovery may be expected. If the disease momentum has passed, life will be difficult to preserve.
When using toxic drugs to treat disease, start with a dose as small as millet seeds. Stop once the disease is gone. If the disease persists, double the dose. If it still persists, increase to ten times the initial dose. Discontinue once the disease is eliminated.
Treat cold conditions with hot-natured drugs; treat heat conditions with cold-natured drugs; treat indigestion of food with emetic or purgative drugs; treat Gui Zhu (ghostly afflictions) and Gu poison with toxic drugs; treat abscesses, sores, and tumors with external sore medications; treat wind-dampness with wind-damp dispelling drugs. Each should be chosen according to its appropriateness.
For diseases located above the chest and diaphragm, eat first, then take medicine. For diseases located below the heart and abdomen, take medicine first, then eat. For diseases located in the limbs and blood vessels, take medicine on an empty stomach in the morning. For diseases located in the bone marrow, take medicine when full at night.
Major severe diseases include: Wind-stroke (Zhong Feng), Cold Damage (Shang Han), alternating chills and fever, Warm Malaria (Wen Nian), sudden evil attack (Zhong E), Cholera-like disorder (Huo Luan), abdominal edema, intestinal dysentery (Chang Pi), obstruction of urination and defecation, Ran Tan (running piglet sensation), upward rushing Qi, cough and counterflow qi, vomiting, jaundice, Xiao Ke (wasting-thirst syndrome), retained fluid, Pi Shi (accumulated phlegm-food), hard accumulations, Zheng Jia (masses), fright evil, epilepsy, ghostly afflictions, throat bi (obstruction), toothache, deafness, blindness, metal wounds, fractures, abscesses, malignant sores, hemorrhoids, goiter, and neck swellings.
Men commonly suffer from Five Exhaustions (Wu Lao), Seven Injuries (Qi Shang), deficiency and fatigue, and emaciation. Women commonly suffer from leukorrhea (Dai Xia) and metrorrhagia (Beng Zhong).