吴又可用槟芍汤，系治瘟疫之里症而兼痢者。若有外症，仍当解表，必如喻嘉
言分三次治法，始足以尽其变。至表里俱病者，又当表里分治，总宜活变，不可胶执。惟松花
散治瘟毒热痢，颇着奇效，未可以易而忽之。又按伤寒便脓血，有误发淋家汗而然者，用猪苓汤；
有病在少阴者，治以桃花汤。诸说于瘟痢总不宜用。盖痢由瘟而作者，始终一于为热也。惟杂疫中
痢疾，原无瘟疫之头痛身热，发热自汗，以及心腹痞满不食，谵语等表里诸症。而沿门阖户止患
痢疾者，则有虚实寒热之殊，其治法亦因之各异矣。凡痢身热脉大者难治，身热脉小者易治。
松花散 治瘟毒热痢。
松花（二三钱）
煎薄荷滚汤，入蜜调服，以愈为度，无不效者。取松花法∶于四月初，看松梢所抽黄穗如麦
穗者，趁硬摘取，摊在布被单上，晒干即有面落下如蒲黄。瓷器收贮，伏天必晒，否则穿发，取
黄穗不可早，早则嫩而少黄面，又不可迟，迟
则花蕊飞而穗成空壳矣。看其穗硬而带黄色，大如稻粒则取之。又松花和入米粉中，入白糖可蒸
糕食，甚香美，呼为松花饼。
大黄酒 便脓血，里急后重，腹痛，昼夜烦不止。大黄五钱，好黄酒一两盅，浸一宿，次
日温饮。
凡疟寒热如期而发，余时脉静身凉常也，以疟法治之。设传胃者，必现里症，（应下之症。）名
为瘟疟，以疟法治者死。当以瘟疫法治之。此症下后，里症除，寒热独存者，是瘟减疟在。疟邪
未去者，宜疏，清脾饮。邪去而疟势在者，宜截，不二饮。势在挟虚者，宜补，四君子汤。三
方见疟门，不附载。
丹蒿散 治瘟疟不止。
黄丹（五钱，炒） 青蒿（童便浸，晒干，二两，为末）
每剂服二钱，寒多酒服，热多茶服。
鹤龄枣 治瘟疫邪疟。取红枣一枚，咒曰∶华表柱。一气念七遍，望西北方取气
一口，吹枣上，令病者吃之。
便蜜饮 瘴疠诸疟，无问新久。
童便（一盅） 白蜜（二匙）
共搅，去白沫，顿服取吐，碧绿痰出为妙，不然终不除。
吴又可使用槟芍汤，这是治疗瘟疫里证兼有痢疾症状的方剂。如果伴有外感表证，仍应当先解除表邪，必须像喻嘉言提出的分三次治疗方法那样，才能充分应对病情的各种变化。至于表证和里证同时存在的，又应当分别处理表里，总体原则是灵活变通，不可固执拘泥。只有松花散治疗瘟毒引起的热痢，效果显著，不可以因为它简单而轻视它。另外，按照伤寒论中关于大便脓血的情况，有的是因为误用发汗法治疗淋病患者所致，应使用猪苓汤；有的是病位在少阴经的，用桃花汤治疗。这些说法对于瘟疫引起的痢疾总归是不适用的。因为由瘟疫引发的痢疾，从头到尾都属于热证。只有在普通疫病中的痢疾，原本没有瘟疫常见的头痛身热、发热自汗，以及心腹痞满不想吃饭、说胡话等表里诸症。而一家一户都只患痢疾的情况，则有虚证、实证、寒证、热证的区别，其治疗方法也因此各不相同。凡是患痢疾身体发热且脉象大的难治，身体发热但脉象小的易治。
松花散：治疗瘟毒热痢。
松花（二三钱）
用薄荷煎煮的滚开水冲服，加入蜂蜜调和服用，以痊愈为标准，没有不有效的。采集松花的方法：在四月初，观察松梢抽出的黄色穗状物像麦穗一样的，趁其坚硬时采摘下来，摊在布被单上晒干，就会有粉末落下像蒲黄一样。用瓷器收藏储存，伏天时必须晾晒，否则会蛀蚀生虫。采集黄穗不可太早，早了则嫩且黄色的粉少；也不可太迟，迟了花蕊飞散穗子变成空壳。看它的穗子坚硬且带黄色，大小如稻粒就可以采集了。另外松花混合米粉中加入白糖可以蒸糕食用，非常香美，被称为松花饼。
大黄酒：治疗大便脓血，里急后重，腹痛，昼夜烦躁不止。大黄五钱，优质黄酒一两盅，浸泡一夜，第二天温饮。
凡是疟疾寒热交替按时发作，其余时间脉象平静身体凉爽是正常的，按治疗疟疾的方法处理。如果病邪传入胃腑，必然出现里证（应当用下法的症状），称为瘟疟，如果按治疗疟疾的方法处理会导致死亡。应当按治疗瘟疫的方法处理。此症经过攻下后，里证消除，只剩下寒热往来，这是瘟邪减轻而疟邪仍在。疟邪未去的，宜用疏解法，用清脾饮。邪气已去但疟疾势头仍在的，宜用截断法，用不二饮。势头仍在且夹杂虚证的，宜用补益法，用四君子汤。以上三方见疟疾章节，此处不附载。
丹蒿散：治疗瘟疟不止。
黄丹（五钱，炒制） 青蒿（童便浸泡，晒干，二两，研为末）
每剂服用二钱，寒多者用酒送服，热多者用茶送服。
鹤龄枣：治疗瘟疫邪疟。取红枣一枚，念咒语说：“华表柱。”一口气念七遍，向西北方向吸取一口气，吹在枣子上，让病人吃下去。
便蜜饮：治疗瘴疠各类疟疾，不论新病久病。
童便（一盅） 白蜜（两匙）
共同搅拌，去掉白色泡沫，一次性服用以引起呕吐，吐出碧绿色的痰为好，否则终究不能除根。
Wu Youke used Bing Shao Tang (Betel Nut and Peony Decoction), which is a formula for treating interior syndromes of plague accompanied by dysentery. If exterior symptoms are present, the exterior should still be resolved first. One must follow Yu Jiayan's method of three-stage treatment to fully address the variations in the disease. In cases where both exterior and interior are affected, they should be treated separately; the general principle is flexibility and adaptation, avoiding rigid adherence. Only Song Hua San (Pine Flower Powder) shows remarkable efficacy in treating heat-dysentery caused by plague-toxin, and it should not be neglected due to its simplicity. Furthermore, regarding pus and blood in stool as described in Shanghan Lun (Treatise on Cold Damage), some cases result from erroneous sweating therapy applied to patients with strangury, treated with Zhu Ling Tang (Polyporus Decoction); others involve the Shaoyin (Lesser Yin) channel, treated with Tao Hua Tang (Peach Kernel Decoction). These approaches are generally unsuitable for plague-induced dysentery. This is because dysentery arising from plague is consistently characterized by heat throughout its course. However, ordinary epidemic dysentery lacks the typical plague symptoms such as headache, fever, aversion to cold, spontaneous sweating, epigastric and abdominal fullness, anorexia, and delirium. In situations where an entire household suffers only from dysentery, there are distinctions between deficiency and excess, cold and heat patterns, and thus the treatment methods vary accordingly. Dysentery accompanied by fever and a large pulse is difficult to treat, whereas fever with a small pulse is easier to treat.
Song Hua San (Pine Flower Powder): Treats heat-dysentery caused by plague-toxin.
Song Hua (Pine Pollen) (2-3 qian)
Brew fresh mint leaves with boiling water, add honey, and take orally until cured. It is invariably effective. Method for collecting pine pollen: In early April, observe the yellow spikes emerging from the pine tips that resemble wheat ears. Pick them while they are still firm, spread them on a cotton sheet, and dry them in the sun until powder falls off resembling Puhuang (Sparganium Spore). Store in porcelain vessels; during the dog days of summer, sun-dry again to prevent insect infestation. Do not collect too early, as the spikes will be tender and yield less yellow powder; do not collect too late, as the florets will disperse leaving empty husks. Collect when the spikes are firm, yellowish, and the size of rice grains. Additionally, mixing pine pollen with rice flour and white sugar allows for steaming cakes, known as Song Hua Bing (Pine Flower Cake), which is very fragrant and delicious.
Da Huang Jiu (Rhubarb Wine): Treats pus and blood in stool, tenesmus, abdominal pain, and incessant restlessness day and night.
Da Huang (Rhei Radix et Rhizoma) (5 qian), soaked overnight in 1 liang of good yellow wine. Drink warm the next day.
Malaria typically presents with periodic chills and fever, while the pulse remains calm and the body cool at other times; this is normal and should be treated according to malaria protocols. If the pathogen transmits to the Stomach, interior syndromes will manifest (symptoms requiring purgation), termed Wen Nue (Plague Malaria). Treating this as ordinary malaria leads to death; it must be treated according to plague protocols. After purgation, if the interior syndrome resolves but chills and fever persist, it indicates that the plague pathogen has diminished while the malaria pathogen remains. For persistent malaria pathogen, use a dispersing method with Qing Pi Yin (Clear Spleen Decoction). If the pathogen is gone but the malaria trend continues, use a blocking method with Bu Er Yin (Not Two Decoction). If the trend persists accompanied by deficiency, use a tonifying method with Si Jun Zi Tang (Four Gentlemen Decoction). These three formulas are found in the Malaria section and are not reproduced here.
Dan Hao San (Cinnabar and Artemisia Decoction): Treats intractable plague malaria.
Huang Dan (Lead Oxide) (5 qian, stir-fried), Qing Hao (Artemisiae Annuae Herba) (steeped in child's urine, dried, 2 liang, powdered).
Take 2 qian per dose. Take with wine if chills predominate, or with tea if heat predominates.
He Ling Zao (Crane-Age Date): Treats plague-related malignant malaria. Take one red date, recite the incantation "Hua Biao Zhu" (Flower Pillar Post) seven times in one breath, inhale qi from the northwest direction, blow onto the date, and have the patient consume it.
Bian Mi Yin (Urine and Honey Drink): Treats miasma-induced various malarias, regardless of whether new or chronic.
Tong Bian (Child's Urine) (1 zhong), Bai Mi (White Honey) (2 chi).
Stir together, remove white foam, and take in one dose to induce vomiting. The emergence of emerald-green phlegm is ideal; otherwise, the condition will not be thoroughly eradicated.