正阳门外，蒋家胡同口内，祥泰布铺，祁某，晋人也。长郎病疫，原诊谢以不治，又延一医，亦不
治。及至邀余，已七日矣。诊其脉，六部全伏；察其形，目红面赤，满口如霜，头汗如雨，四肢如冰；稽
其症，时昏时躁，谵妄无伦，呕泄兼作，小水癃闭，周身斑疹，紫黑相间，幸而松活，浮于皮面，毒虽盛
而犹隐跃，此生机也。查看前方，亦用犀、连，大剂不过钱许，乃杯水之救耳！予曰∶令郎之症最险，不
畏予药过峻，死中求活，不然，变在十四日。祁恳甚切，予用大剂，石膏八两，犀角六钱，黄连五钱，余
佐以本方之味，加伏龙肝一两，滑石五钱，木通三钱，猪苓、泽泻各二钱，更加生地一两，
紫草三钱，归尾三钱，大青叶二钱。以色紫黑也，连投二服。至九日脉起细数，手足回温，
呕虽止而泄如旧，仍用本方去伏龙肝，又二服。至十一日，脉转洪数，头汗遂止，黑斑变紫，小水亦利，
大便亦实，但妄谵如前，身忽大热，烦躁更甚，大渴不已，以火外透也，仍用本方去滑石、木通、猪苓、泽泻，
加花粉、山豆根。以喉微痛也，更以冰水与服，以济其渴。又二帖，色转深红，热势稍杀，谵妄间有，
犹渴思冰，投本方减生地五钱去归尾、紫草、豆根、花粉。又二服，诸症已退十分之三，药减四分之一，但
饮水而不思食。祁疑而叩曰∶病虽减，而十数日不食，尚能生乎？予曰，生矣，按法治之，二十一日方可全愈。
又二服，斑化多半，胃气渐开，热亦大减，照本方药减四分之二，去大青叶。又二服，斑点全消，饮食旋食旋
饿，方能起坐，诊其脉，尚有六至，犹有余热，不即清之，其势复张，更难为力，犹用石膏二两四钱，犀角三钱，黄连
二钱，余亦类减。十九日用石膏一两二钱，犀角二钱，黄连一钱，加乌梅三个，酸以收之也。予曰∶前言二十一日，方
能成功，今已十九日矣，令郎如此，可见前言之不谬也。祁某喜曰∶若非立定主意，几为众口所误，初立此方，体全堂
不肯卖药，叩其所以，言误开分两，以八钱为八两、六分为六钱耳。予历指同乡服此得痊者颇多，虽卖。犹嘱以再三斟
酌。二十日犹用石膏八钱，犀角钱半，黄连八分，加洋参二钱，麦冬三钱，归身二钱，川芎一钱，以调气血。二十一日
用八珍汤加麦冬、五味，立方需大纸一张。昨言初方药店不肯发药，今令郎已愈，录一治法于方前，计服石膏、
黄连。犀角若干，使彼知予用药之奇，即药铺亦未之见也。
录曰∶瘟毒发斑，疫症之最重者，然有必活之方。无如医家不敢用，病家不敢服，甚至铺家不敢卖，有
此“三不敢”，疫疹之死于误者，不知凡几，可胜叹哉！令郎之症，蒙相信之深，邀予延医。予用大剂连投十
五帖，今已全安，计用石膏六斤有另，犀角七两有另，黄连六两有另。此前人所未有，后人所未见，故笔之
于书，以征奇效。
正阳门外，蒋家胡同口内的祥泰布铺，住着一位姓祁的山西人。他的长子患瘟疫，起初医生诊断为不治之症，后来请了另一位医生，也认为无法治疗。等到邀请我时，病情已经持续七天了。诊察其脉象，六部脉全部伏匿不见；观察其形体，眼睛发红，面色赤红，满口舌苔白如霜，头部出汗如雨下，四肢冰冷如冰；审视其症状，时而昏迷时而烦躁，胡言乱语毫无条理，呕吐与腹泻同时发作，小便点滴不通，全身出现斑疹，颜色紫黑相间，幸好斑疹形态松软活泼，浮于皮肤表面，虽然毒邪旺盛但仍有隐隐跃动之象，这是生机尚存的迹象。查看之前的处方，也使用了犀角、黄连，但大剂量不过一钱左右，这简直是杯水车薪！我说：“令郎的病症最为险恶，如果不畏惧我的药力过于峻猛，在死中求活，否则，变故将在第十四天发生。”祁某恳切请求，我使用大剂量方药：石膏八两，犀角六钱，黄连五钱，其余辅助以本方的药物，加入伏龙肝一两，滑石五钱，木通三钱，猪苓、泽泻各二钱，再加入生地一两，紫草三钱，当归尾三钱，大青叶二钱。因为斑色紫黑，连续服用两剂。到了第九天，脉象转为细数，手足回暖，呕吐虽止但腹泻依旧，仍然使用原方去掉伏龙肝，又服两剂。到了第十一天，脉象转为洪数，头汗停止，黑斑变为紫色，小便通畅，大便成形，只是胡言乱语如前，身体突然高热，烦躁更加严重，极度口渴，这是因为火毒向外透发的缘故，仍然使用原方去掉滑石、木通、猪苓、泽泻，加入天花粉、山豆根。因为咽喉微痛，更用冰水送服，以缓解其口渴。又服两帖，斑色转为深红，热势稍减，偶尔仍有胡言乱语，依然渴望喝冰水，投予原方减少生地五钱，去掉当归尾、紫草、山豆根、天花粉。又服两剂，各种症状已消退十分之三，药量减少四分之一，但只喝水不想吃东西。祁某怀疑并问道：“病虽然减轻，但十几天不进食，还能活吗？”我说：“能活，按照法治疗，二十一天才可以完全痊愈。”又服两剂，斑疹化去大半，胃气渐开，热势也大大减少，照原方药量减少二分之二（即减半），去掉大青叶。又服两剂，斑点全部消失，饮食后很快感到饥饿，才能起身坐立，诊察其脉象，还有六至（每呼吸一次脉搏跳动六次），还有余热，如果不立即清除，病势会再次嚣张，更难处理，仍然使用石膏二两四钱，犀角三钱，黄连二钱，其余药物也类似减量。第十九日用石膏一两二钱，犀角二钱，黄连一钱，加入乌梅三个，利用酸味来收敛正气。我说：“之前说二十一天，才能成功，现在已经是十九天了，令郎的情况，可见之前的话没有错误。”祁某高兴地说：“如果不是下定决心，几乎被众人的议论所误导，当初定下这个方子，体全堂药店不肯卖药，询问其原因，说是误开了分量，把八钱当成八两、六分当成六钱罢了。我列举同乡服用此方痊愈者很多，才肯卖。还嘱咐他们再三斟酌。第二十天仍用石膏八钱，犀角一钱半，黄连八分，加入西洋参二钱，麦冬三钱，当归身二钱，川芎一钱，用来调和气血。第二十一天用八珍汤加麦冬、五味子，开方需要一大张纸。昨天说初方药店不肯发药，如今令郎已经痊愈，记录一种治法在方前，计算服用石膏、黄连、犀角的总量，让他们知道我用药的奇妙，即使是药店也没见过。”
记录道：瘟毒发斑，是疫病中最严重的类型，然而有必定能救活的方子。无奈医生不敢用，病人不敢服，甚至药店不敢卖，有此“三不敢”，因误治而死于疫疹的人，不知有多少，真是令人叹息啊！令郎的病症，蒙受深深的信任，邀请我延医诊治。我使用大剂量连续服用十五帖，如今已经完全安康，共计使用石膏六斤多，犀角七两多，黄连六两多。这是前人未曾有过，后人未曾见过的，所以笔之于书，以证明其奇效。
Outside the Zhengyang Gate, inside the entrance of Jiangjia Hutong, at Xiangtai Cloth Shop, there was a man surnamed Qi from Shanxi. His eldest son suffered from plague (Yi Zheng). The initial physician diagnosed it as incurable, and another physician invited subsequently also deemed it untreatable. By the time I was invited, seven days had passed. Upon examination, the pulse in all six positions was completely hidden (Fu Mai); observing his form, his eyes were red, face flushed, mouth coated with white frost-like coating, head sweating profusely like rain, and limbs cold as ice; examining his symptoms, he alternated between coma and restlessness, spoke deliriously without coherence, suffered from simultaneous vomiting and diarrhea, experienced urinary retention (Long Bi), and had widespread macules and papules on his body, alternating in purple and black colors. Fortunately, they were loose and active, floating on the skin surface; although the toxin was severe, there was still a subtle movement, indicating a sign of life. Reviewing previous prescriptions, Rhinoceros Horn (Xijiao) and Coptis Rhizome (Huanglian) were used, but even in large doses, they amounted to only about one qian, which is like saving a cup of water to quench a cartload of fuel! I said: "Your son's condition is extremely critical. If you do not fear my medicine being too harsh, we can seek life amidst death; otherwise, changes will occur on the fourteenth day." Mr. Qi pleaded earnestly. I prescribed a large dose: Gypsum Fibrosum (Shigao) 8 liang, Rhinoceros Horn (Xijiao) 6 qian, Coptis Rhizome (Huanglian) 5 qian, supplemented with other ingredients of this formula, plus Earth Pillar Clay (Fulonggan) 1 liang, Talcum (Huashi) 5 qian, Akebia Caulis (Mutong) 3 qian, Polyporus (Zhuling) and Alisma Rhizome (Zexie) 2 qian each, plus Rehmannia Root (Shengdi) 1 liang, Arnebia Root (Zicao) 3 qian, Angelica Sinensis Tail (Guiwei) 3 qian, Isatis Leaf (Daqingye) 2 qian. Due to the purple-black color, two doses were administered consecutively. By the ninth day, the pulse became fine and rapid (Xi Shu), hands and feet warmed up, vomiting stopped but diarrhea persisted. The original formula was continued minus Fulonggan, for another two doses. By the eleventh day, the pulse turned surging and rapid (Hong Shu), head sweat ceased, black macules turned purple, urination became smooth, stool solidified, but delirium remained as before. Suddenly, high fever appeared, restlessness intensified, and extreme thirst occurred. This indicated the fire toxin was penetrating outward. The original formula was continued minus Huashi, Mutong, Zhuling, and Zexie, adding Tianhuafen (Trichosanthes Root) and Shandougen (Sophorae Tonkinensis Radix). Due to slight throat pain, ice water was used to administer the medicine to relieve thirst. After two more doses, the macules turned deep red, heat slightly subsided, delirium occurred intermittently, and he still craved ice. The original formula was modified by reducing Shengdi by 5 qian and removing Guiwei, Zicao, Shandougen, and Tianhuafen. After two more doses, symptoms improved by three-tenths, dosage reduced by one-quarter, but he drank water without appetite. Mr. Qi doubted and asked: "Although the illness has lessened, can he survive after ten-plus days without food?" I replied: "He will live. Following this treatment, full recovery will take twenty-one days." After two more doses, more than half of the macules resolved, stomach qi gradually opened, and heat significantly decreased. The dosage was halved again, removing Daqingye. After two more doses, all spots disappeared, he felt hungry shortly after eating, and could sit up. Pulse examination showed six beats per breath (Liu Zhi), indicating residual heat. If not cleared immediately, the pathogen would surge again, making treatment difficult. Gypsum Fibrosum (Shigao) 2 liang 4 qian, Rhinoceros Horn (Xijiao) 3 qian, Coptis Rhizome (Huanglian) 2 qian were used, with other herbs similarly reduced. On the nineteenth day, Gypsum Fibrosum (Shigao) 1 liang 2 qian, Rhinoceros Horn (Xijiao) 2 qian, Coptis Rhizome (Huanglian) 1 qian, plus three Chinese Plum (Wumei) were used to utilize sourness for astringency. I said: "I previously stated success would come on the twenty-first day. It is now the nineteenth day. Your son's condition proves my words were correct." Mr. Qi joyfully said: "If I hadn't made up my mind, I might have been misled by public opinion. Initially, when this prescription was set, Titang Pharmacy refused to sell the medicine. Upon inquiry, they claimed a dosage error, mistaking 8 qian for 8 liang and 6 fen for 6 qian. I cited many fellow townspeople who recovered using this method, so they agreed to sell, advising careful consideration. On the twentieth day, Gypsum Fibrosum (Shigao) 8 qian, Rhinoceros Horn (Xijiao) 1.5 qian, Coptis Rhizome (Huanglian) 0.8 qian, plus American Ginseng (Yangshen) 2 qian, Ophiopogon Tuber (Maidong) 3 qian, Angelica Sinensis Body (Guishen) 2 qian, Ligusticum Rhizome (Chuanxiong) 1 qian were used to regulate Qi and Blood. On the twenty-first day, Bazhen Decoction (Eight Treasures Decoction) added Maidong and Schisandra Berry (Wuweizi) was used; the prescription required a large sheet of paper. Yesterday, the pharmacy refused the initial prescription; today, your son is cured. I record this treatment method before the formula, calculating the total amount of Shigao, Huanglian, and Xijiao used, so they may know the uniqueness of my medication, something even pharmacies have rarely seen."
Recorded: Plague toxin causing macules is the most severe type of epidemic disease, yet there are formulas that guarantee survival. Unfortunately, physicians dare not use them, patients dare not take them, and even pharmacies dare not sell them. With these "three dreads," countless people die from misdiagnosis and mistreatment of plague rashes, which is truly lamentable! Your son's condition, trusting me deeply, led to my invitation. I used large doses continuously for fifteen packs, and now he is fully recovered. Total usage: over 6 jin of Gypsum Fibrosum (Shigao), over 7 liang of Rhinoceros Horn (Xijiao), and over 6 liang of Coptis Rhizome (Huanglian). This is unprecedented by predecessors and unseen by successors, hence recorded in this book to demonstrate its miraculous efficacy.