夫太极而生两仪，人道而有夫妇，男女交合，无欲不行，无火不动。恣情纵欲，而火毒遗
于精血之间，小儿痘疹之毒，由此而成。然痘之与疹，虽皆胎毒，原同而证异。孕成之初，先有
脏而后有腑，腑属阳而脏属阴。痘在里，从肌肉内起，故难；疹在表，从皮肤间出，故易。痘属
阴，阴主静，有形有汁，颗粒不动而合偶数；疹属阳，阳主动，有形无汁，乍出乍收，一日三见
，三日九发而合奇数也。其见证之不同者，痘则首尾不可吐泻，能进饮食为吉。如吐泻，乃毒火
盛极而攻冲；不食，由毒火郁遏而壅滞，药不可治。疹则吐泻并作，饮食不进为吉。得吐泻，则
毒火由此而泄；不食，则空虚而毒火疏通。痘宜益气生血，药用补托而求内实；疹宜养阴制阳，
药用解散而忌内实。痘则有平顺、有虚寒、有实热、有血热。疹则皆属实热。毒火一从清凉，忌
辛温药。痘以头面多为逆；疹以头面多为顺。皆宜房室固密，衣衾浓覆，常令和暖则腠理疏豁而
易出，又须严守禁戒。如或风寒外袭，触犯避忌，皆能以轻变重，以安易危。但疹之日数少，痘
之日数多。若谓痘重而疹轻，不知疹之变态，作于顷刻，危亡之机，甚于痘也。
（即天疮、百岁疮）
凡看痘之法，治痘之方，当知有顺、逆、险三种之分。顺候但宜谨慎调理，不必服药。如不
宜表而
表，则成斑烂难收之患；不须补而补，则有助毒发痈之愆。或痘未出而药用清凉，痘得寒而反为
凝滞；毒未解而妄行温补，毒得热而反不化浆，转增他剧，岂非药之过欤，设谓痘轻不加敬谨，
有犯禁戒，变而为重，诚非失药之咎矣！逆候服药，诚然无功，若以仁术论之，姑与立方，勉强
治疗，十中幸得生一，宁非无量功德乎？险证全籍药饵合宜，调理谨慎。父母保护如法则从顺，
不尔则从逆矣。其始也，必遇岁火太过，热毒流行，则痘毒因之而发。为证之初，与伤寒相似。
发热烦躁，面赤唇红，头疼身痛，喷嚏呵欠，咳嗽痰涎。有因外感风寒；有因伤食吐泻，有因时
气传染，有因跌扑惊恐致成。盖痘疹之毒伏于肾经，痘毒既发，肾经应无证矣。故必预验耳冷、
尻冷（尻，尾 骨、）足冷（是知肾经无证，若三处热而腰疼，见痘必凶。当知毒火极盛，肾经传之
不出也、）中指冷、鼻尖冷、耳后筋纹（淡红，少而轻；深红，多而重、）眼目困倦，而颧有红纹
，皆出痘之候。
太极化生阴阳两仪，人类社会中存在夫妇关系，男女交合，没有欲望就无法进行，没有阳气（命门之火）就无法发动。如果放纵情欲，导致火毒遗留在精血之间，小儿的痘疹之毒便由此形成。然而痘与疹，虽然都是胎毒，本源相同但证候不同。怀孕初期，先形成脏而后形成腑，腑属阳而脏属阴。痘生于体内深处，从肌肉内部发起，所以难治；疹生于体表浅处，从皮肤间发出，所以易治。痘属阴，阴主静，痘粒有形且有脓汁，颗粒固定不动且符合偶数规律；疹属阳，阳主动，疹点有形但无脓汁，忽出忽收，一天出现三次，三天发作九次，符合奇数规律。它们见证的不同之处在于：痘病从头到尾都不宜使用吐法和泻法，能够进食饮食为吉兆。如果出现吐泻，是因为毒火极盛而向上攻冲；如果不能进食，是因为毒火郁结阻滞，这种情况药物难以治疗。疹病则吐泻并作为佳兆，不能进食反而吉利。能够吐泻，毒火便能由此排出；不能进食，则体内空虚，毒火得以疏通。痘病适宜益气生血，用药以补益托毒为主，以求内部充实；疹病适宜养阴制阳，用药以解散透邪为主，忌讳内部壅实。痘病有平顺、虚寒、实热、血热等不同类型；疹病则都属于实热。治疗痘病毒火应以清凉为主，忌用辛温药物。痘病以头面部多发为逆证；疹病以头面部多发为顺证。两者都适宜居室密闭，衣被厚盖，经常保持温暖，这样腠理疏松开阔，痘疹容易发出，同时也必须严格遵守禁忌。如果遭受风寒外袭，触犯避忌，都能使轻症变重，使安稳变为危险。只是疹病的病程天数少，痘病的病程天数多。如果说痘病重而疹病轻，这是不了解疹病变化迅速，顷刻之间发生变异，其危亡之机，甚至比痘病更严重。
（即天疮、百岁疮）
凡是观察痘病的方法，治疗痘病的方剂，应当知道分为顺、逆、险三种情况。顺证只需谨慎调理，不必服药。如果不适合发汗却强行发汗，就会造成痘疮溃烂难以收敛的祸患；不需要补益却强行补益，就会助长毒气引发痈肿的过失。或者痘疮尚未发出就使用清凉药物，痘疮遇到寒气反而凝滞；毒邪未解却妄行温补，毒邪遇到热气反而不能化脓成浆，转而增加其他严重病症，这难道不是药物的过错吗？假如认为痘病轻微而不加敬慎，触犯禁忌，病情变重，这确实不是用药失误的罪过啊！逆证服药，确实往往无效，但如果从仁术的角度来看，暂且开具处方，勉强治疗，十人中侥幸救活一个，岂不是无量的功德吗？险证完全依赖药物适宜和调理谨慎。父母保护得当遵循法则则转为顺证，不这样做则转为逆证。起初，必定遇到岁运火气太过，热毒流行，痘毒因此发作。发病之初，症状与伤寒相似。发热烦躁，面色红赤，嘴唇红润，头痛身痛，打喷嚏呵欠，咳嗽伴有痰涎。有的因为外感风寒；有的因为伤食导致吐泻，有的因为时气传染，有的因为跌打惊恐所致。大概痘疹之毒潜伏于肾经，痘毒既然已经发出，肾经应当没有症状了。所以必须预先验证耳垂冷、尻骨冷（尻，指尾骨）、足部冷（以此可知肾经无症状，如果这三处发热且腰痛，见到痘疹必然凶险。应当知道毒火极盛，肾经无法将毒邪传出）、中指冷、鼻尖冷、耳后筋纹（颜色淡红，纹路少且轻；颜色深红，纹路多且重）、眼睛困倦，以及颧骨部位有红纹，这些都是出痘的征兆。
Taiji generates the Two Modes (Yin and Yang); in human society, there are husbands and wives. Male-female intercourse cannot occur without desire, nor can it be activated without Fire (Mingmen Fire). Indulgence in lust causes Fire-Toxin to remain between Essence and Blood, thereby forming the toxin of infantile smallpox and measles. However, although both smallpox and measles are fetal toxins with the same origin, their manifestations differ. At the beginning of pregnancy, Zang organs form before Fu organs; Fu organs belong to Yang, while Zang organs belong to Yin. Smallpox arises from within the interior, emerging from deep within the muscles, thus it is difficult; measles emerges from the exterior, appearing between the skin, thus it is easy. Smallpox belongs to Yin; Yin governs stillness. It has form and contains pus, the granules remain stationary, and they conform to even numbers. Measles belongs to Yang; Yang governs movement. It has form but no pus, appearing and disappearing intermittently, seen three times a day, erupting nine times over three days, conforming to odd numbers. The differences in their clinical presentations are as follows: for smallpox, neither vomiting nor purging should be used from start to finish; the ability to eat is auspicious. If vomiting or purging occurs, it is because the Fire-Toxin is extremely abundant and attacking upward; inability to eat indicates that the Fire-Toxin is depressed and obstructed, a condition resistant to treatment. For measles, simultaneous vomiting and purging are auspicious, while inability to eat is favorable. Vomiting and purging allow the Fire-Toxin to drain out; inability to eat leaves the interior empty, allowing the Fire-Toxin to circulate freely. Smallpox requires tonifying Qi and generating Blood, using formulas that tonify and support to seek internal solidity. Measles requires nourishing Yin and controlling Yang, using formulas that release and disperse while avoiding internal stagnation. Smallpox presents as smooth/normal, deficiency-cold, excess-heat, or blood-heat. Measles is always excess-heat. Treatment for the Fire-Toxin of measles should employ cooling methods, avoiding acrid-warm herbs. For smallpox, extensive eruption on the head and face is an adverse sign; for measles, extensive eruption on the head and face is a favorable sign. In both cases, the living quarters should be sealed tightly, and clothing and bedding should be thickly layered to maintain warmth. This keeps the Couli (pores) open and facilitates eruption. Strict adherence to taboos is also required. If attacked by external Wind-Cold or if taboos are violated, mild conditions can become severe, and stability can turn into danger. Although measles has fewer days of duration than smallpox, claiming that smallpox is severe and measles is light ignores the rapid transformation of measles, which can change in an instant, making its critical state more dangerous than that of smallpox.
(Also known as Heavenly Blister or Hundred-Year Blister)
When observing smallpox and prescribing treatments, one must understand the classification into Smooth, Adverse, and Critical categories. For Smooth patterns, only careful regulation is needed; medication is unnecessary. If diaphoresis is applied when inappropriate, it leads to ulceration and difficulty in healing; if tonification is applied when unnecessary, it aids the toxin and causes carbuncles. If cooling herbs are used before the rash erupts, the cold causes stagnation; if warm tonics are recklessly used before the toxin resolves, the heat prevents suppuration, worsening other symptoms. Is this not the fault of the medicine? Conversely, if one neglects caution for mild smallpox and violates taboos, leading to severity, this is indeed not due to medicinal error! For Adverse patterns, medication is often ineffective. However, from the perspective of benevolent medicine, one should still prescribe and attempt treatment; saving even one out of ten would be boundless merit. Critical patterns rely entirely on appropriate medication and careful nursing. If parents protect the patient according to proper rules, the condition becomes Smooth; otherwise, it becomes Adverse. Initially, this often coincides with years of excessive Fire Qi and circulating Heat-Toxin, triggering the smallpox toxin. The initial presentation resembles Taiyang disease (Exogenous Cold Damage). Symptoms include fever, restlessness, red face, red lips, headache, body pain, sneezing, yawning, cough, and phlegm. Causes may include external contraction of Wind-Cold, food injury leading to vomiting/diarrhea, seasonal epidemic transmission, or fright/fall injuries. Generally, the toxin of smallpox and measles lies dormant in the Kidney Meridian. Once the smallpox toxin erupts, the Kidney Meridian itself should show no symptoms. Therefore, one must pre-test for coldness at the earlobes, the sacrum (tailbone), and the feet (indicating the Kidney Meridian is symptom-free; if these areas are hot accompanied by lower back pain, the prognosis is ominous, indicating extreme Fire-Toxin failing to exit via the Kidneys). Other signs include coldness at the middle finger, coldness at the nasal tip, vein patterns behind the ears (pale red, few/light; deep red, many/heavy), eye fatigue, and red streaks on the cheekbones. These are all precursors to eruption.