不得眠阴阳皆有之正病于不得眠者阳明也若少阴当病于欲寐今乃不得眠缘阳气入少阴经非少阴正病也有因汗下而
然者有不因汗下而然者有因火逆而然者治见本条但不得眠皆为热证其有太阳汗下之后昼日燥躁不得眠一证虽用干姜附
子汤盖复其汗下所亡之阳非治其所感之寒病也不得眠为常证然少阴脉沉细自利烦躁不得眠者死伤寒发热下利厥逆烦躁
不得卧者亦死俱为正气弱阳不能复故也 活人云汗为火之液汗多则神昏故不眠大热则神不清故不眠大下则动血心主血
故不眠瘥后热气未散阴气未复故不眠
太阳 病二三日不得卧但欲起心下必结脉微弱者此有寒分也桂枝加浓朴杏子汤 伤寒脉浮以火劫之惊狂起卧不
得
安者桂枝去芍药加蜀漆龙骨牡蛎救逆汤 下后复发汗昼日烦躁不得眠夜而安静不呕不渴无表证脉沉微身无大热干姜附
子汤 衄家不可汗汗则额上陷脉急紧直视不 不得眠(黄芩芍药汤)伤寒下后心烦腹满卧起不安者栀子浓朴汤 发汗吐
下后虚烦不得眠反复颠倒心中懊 栀子豆豉汤太阳病发汗后胃中干燥不得眠欲饮水者少与之则愈
阳明 身热目疼鼻干不得卧尺寸脉俱长者阳明受病也病患小便不利大便乍难乍易时有微热喘冒不能卧者有燥屎
也宜大承气汤 阳明病脉浮而紧咽燥口苦腹满而喘发热汗出不恶寒反恶热身重若加烧针必怵惕烦躁不眠宜栀子豉汤
少阴 病欲寐二三日后心烦不得卧者黄连阿胶汤主之
黄连阿胶汤方
黄连(四两) 黄芩(二两) 芍药(二两) 阿胶(三两) 鸡子黄(二枚)上五味
以水五升先煮三物取二升去滓纳胶熔尽少冷纳鸡子黄搅令和温服七合日三服(成 阳有余以苦除之黄连黄芩之苦以除热
阴不足以甘补之鸡子黄阿胶之甘以补血酸收也泄也芍药之酸收阴气而泄邪热也 然服鸡子黄其病有不愈者今议加当归
人参茯苓白术各等分与前药四味服之立效)
少阴病下利欲寐六七日后咳而呕渴心烦不得眠者宜猪苓汤(论见下利)少阴病但欲寐脉沉细不烦欲吐至五六日自利
复烦躁不得寐者死 发热下利厥逆烦躁不得卧者死
吴 太阳脉浮数身疼无汗烦躁不眠者宜汗之则愈 阳明标热头额痛目疼身热鼻干不得卧脉长者宜葛根解肌汤汗
之
若自汗脉洪数表里俱热烦渴舌燥饮水者白虎加人参汤主之若蒸蒸发热大便秘硬者调胃承气汤下之外有伤寒已解或因食
复剧烦闷干呕口燥呻吟错语不得眠者黄连解毒汤主之若表里大热舌燥饮水者人参白虎汤合解毒汤主之 凡少阳发热口
苦心烦不得眠脉弦数者小柴胡加黄连山栀子之类若虚弱人津液不足者加麦门冬酸枣仁之类 太阳病发汗后不得眠脉浮
数微热烦渴小便不利者五苓散主之脉数大者人参白虎汤或竹叶石膏汤不可用五苓也 凡汗下后虚烦不得眠者加味温胆
汤酸枣仁汤栀子乌梅汤朱砂安神丸之类选而用之
附
酸枣仁汤 治虚烦扰奔气在胸中不得眠者
酸枣仁(炒) 人参 茯苓(各一钱半) 桂心(五分) 石膏(二钱半) 知母 甘草(各一钱) 生姜(三片)
上作一服水二钟煎至一钟去滓临卧服
千金流水汤 治虚烦不得眠
麦门冬(去心) 半夏 甘草 黄连 远志 人参 萆 (以上各一钱) 茯神 酸枣仁(各一钱半) 桂心(五
分) 生姜(三片) 米(一合)上用长流水二钟半先煮水令蟹目沸以杓扬万遍取汤二钟煎药至一钟去滓温服
加味温胆汤 治太阳病后虚烦不得眠此胆寒也
半夏(洗) 酸枣仁(炒各一钱半) 绿枳实 陈皮 甘草(各一钱) 人参(二钱半) 茯神(二钱) 竹茹(一
团) 生姜(三片)上用水二钟煎至一钟去滓温服若心烦内热者倍加黄连麦门冬若口燥舌干者去半夏加麦门冬五味子天
花粉若表热未清者加软苗柴胡若内虚大便自利者去枳实加白术茯苓若内实心烦颠倒者加山栀仁
酸枣汤 治吐下后昼夜不得眠
酸枣仁(炒二钱半) 麦门冬 茯神 当归身(各二钱) 甘草 知母 川芎(各一钱半) 干姜(三分) 生姜
(三片)上煎法同前
栀子乌梅汤
栀子 黄芩 甘草 人参 麦门冬(各一钱) 柴胡(二钱) 乌梅(二枚) 生姜(三片) 竹叶(十四片)上
煎法同前
黄连解毒汤\x 治大热干呕错语呻吟不得眠
黄连(二钱半) 黄芩 黄柏(各半两) 栀子(四个)水二盏半煎至一盏半去滓分二服
失眠(不得眠)是阴阳失调的常见病症,但在伤寒病中,阳明病是导致失眠的正病。如果属于少阴病,应当表现为嗜睡(欲寐),如今反而出现失眠,这是因为阳气进入少阴经所致,并非少阴病的正证。
导致失眠的原因有因发汗、攻下之后引起的,也有不因发汗、攻下而直接引起的,还有因误用火疗逆证导致的,治疗方法见各相关条文。但总的来说,失眠多属于热证。其中有一种情况是太阳病经过发汗、攻下后,白天烦躁不安、无法入睡,虽然使用干姜附子汤治疗,但这并不是为了治疗所感受的寒邪,而是为了恢复因发汗、攻下而亡失的阳气。
失眠虽然是常见症状,但如果少阴病患者出现脉象沉细、自利(腹泻)、烦躁且无法入睡,这是死证。伤寒发热、下利、四肢厥冷、烦躁且无法平卧的,也是死证。这些都是因为正气虚弱,阳气不能回复的缘故。
《活人书》说:汗是火的液汁,汗出过多则神志昏乱,所以不眠;大热则神志不清,所以不眠;大下则动血,心主血脉,所以不眠;病愈后热气未散、阴气未复,所以不眠。
【太阳病】
太阳病二三日,无法躺卧,只想坐起,心下部必然痞结,脉象微弱的,这是有寒饮停聚。用桂枝加浓朴杏子汤。
伤寒脉浮,被火法劫迫,出现惊狂、起卧不安的,用桂枝去芍药加蜀漆龙骨牡蛎救逆汤。
攻下后又发汗,白天烦躁无法入睡,夜间安静,不呕吐、不口渴、无表证,脉象沉微,身体没有大热的,用干姜附子汤。
经常鼻衄的人不可发汗,若发汗则额部凹陷、脉紧急、直视、无法入睡(用黄芩芍药汤)。
伤寒攻下后,心烦、腹部胀满、卧起不安的,用栀子厚朴汤。
发汗、吐、下后,虚烦无法入睡,翻来覆去、心中懊恼的,用栀子豉汤。
太阳病发汗后,胃中干燥导致无法入睡,想喝水的,少量给予水喝即可痊愈。
【阳明病】
身体发热、眼睛痛、鼻子干、无法躺卧,寸关尺三部脉都长的,是阳明经受病。患者小便不利,大便时而难解时而易解,时有微热、气喘、头目昏眩无法躺卧的,是有燥屎内结,宜用大承气汤。
阳明病,脉浮紧,咽干口苦,腹部胀满而喘,发热出汗,不恶寒反恶热,身体沉重,如果再加烧针,必定惊恐惕怵、烦躁不眠,宜用栀子豉汤。
【少阴病】
少阴病,嗜睡,两三天后心烦无法躺卧的,主治用黄连阿胶汤。
黄连阿胶汤方
黄连(四两) 黄芩(二两) 芍药(二两) 阿胶(三两) 鸡子黄(两枚)
以上五味药,用水五升,先煮前三味药,取药液二升,去渣,纳入阿胶溶化,稍凉后纳入鸡子黄,搅匀,温服七合,每日三次。(成无己注:阳有余用苦味清除,黄连、黄芩之苦以除热;阴不足用甘味补益,鸡子黄、阿胶之甘以补血;酸能收敛,芍药之酸收阴气而泄邪热。然而服用鸡子黄后病有不愈者,现建议加入当归、人参、茯苓、白术各等分,与前药四味同服,立竿见影。)
少阴病下利,嗜睡,六七天后感冒咳嗽、呕吐、口渴、心烦无法入睡的,宜用猪苓汤(论述见下利条)。
少阴病但欲嗜睡,脉沉细,不烦,想吐,到五六天自利又烦躁无法入睡的,是死证。
发热、下利、四肢厥冷、烦躁无法平卧的,是死证。
吴氏按语:
太阳病,脉浮数,身疼无汗,烦躁不眠的,宜发汗则愈。
阳明标热,头额痛,眼痛,身热,鼻干,无法躺卧,脉长的,宜葛根解肌汤发汗。
如果自汗,脉洪数,表里俱热,烦渴,舌燥饮水的,主治用白虎加人参汤。
如果蒸蒸发热,大便秘结坚硬的,用调胃承气汤攻下。
外感伤寒已解,或因饮食复发加重,烦闷干呕,口燥呻吟,胡言乱语,无法入睡的,主治用黄连解毒汤。
如果表里大热,舌燥饮水的,用人参白虎汤合解毒汤主治。
凡是少阳病发热,口苦,心烦无法入睡,脉弦数的,用小柴胡汤加黄连、山栀子之类。
如果是虚弱之人,津液不足的,加麦门冬、酸枣仁之类。
太阳病发汗后,无法入睡,脉浮数,微热,烦渴,小便不利的,主治用五苓散。
脉数大的,用人参白虎汤或竹叶石膏汤,不可用五苓散。
凡是发汗、攻下后,虚烦无法入睡的,选用加味温胆汤、酸枣仁汤、栀子乌梅汤、朱砂安神丸之类。
附录:
酸枣仁汤:治疗虚烦扰攘,奔气在胸中,无法入睡者。
酸枣仁(炒) 人参 茯苓(各一钱半) 桂心(五分) 石膏(二钱半) 知母 甘草(各一钱) 生姜(三片)
以上作一剂,用水二钟,煎至一钟,去渣,临睡前服用。
千金流水汤:治疗虚烦无法入睡。
麦门冬(去心) 半夏 甘草 黄连 远志 人参 萆薢(以上各一钱) 茯神 酸枣仁(各一钱半) 桂心(五分) 生姜(三片) 米(一合)
以上用长流水二钟半,先煮水令蟹眼沸,以勺扬万遍取汤二钟,再煎药至一钟,去渣,温服。
加味温胆汤:治疗太阳病后虚烦无法入睡,此乃胆寒所致。
半夏(洗) 酸枣仁(炒,各一钱半) 绿枳实 陈皮 甘草(各一钱) 人参(二钱半) 茯神(二钱) 竹茹(一团) 生姜(三片)
以上用水二钟,煎至一钟,去渣,温服。若心烦内热者,倍加黄连、麦门冬;若口燥舌干者,去半夏,加麦门冬、五味子、天花粉;若表热未清者,加软苗柴胡;若内虚大便自利者,去枳实,加白术、茯苓;若内实心烦颠倒者,加山栀仁。
酸枣汤:治疗吐下后昼夜无法入睡。
酸枣仁(炒,二钱半) 麦门冬 茯神 当归身(各二钱) 甘草 知母 川芎(各一钱半) 干姜(三分) 生姜(三片)
煎法同上。
栀子乌梅汤
栀子 黄芩 甘草 人参 麦门冬(各一钱) 柴胡(二钱) 乌梅(两枚) 生姜(三片) 竹叶(十四片)
煎法同上。
黄连解毒汤:治疗大热,干呕,胡言乱语,呻吟,无法入睡。
黄连(二钱半) 黄芩 黄柏(各半两) 栀子(四个)
水二盏半,煎至一盏半,去渣,分两次服用。
Insomnia (bude mian) is a common manifestation of yin-yang imbalance. In the context of cold damage diseases, Yangming disease is the primary cause of insomnia. If it were Shaoyin disease, the patient should present with drowsiness (yumi); the current presentation of insomnia occurs because yang qi has entered the Shaoyin meridian, which is not the typical pathology of Shaoyin disease.
Causes for insomnia include those resulting from prior sweating or purging, those arising without such interventions, and those caused by iatrogenic fire therapy errors; treatments are detailed in their respective sections. Generally, insomnia is associated with heat syndromes. However, in cases where Taiyang disease patients experience daytime restlessness and inability to sleep after sweating and purging, Ganjiang Fuzi Tang (Dried Ginger and Aconite Decoction) is used not to treat the contracted cold pathogen, but to restore yang qi lost through excessive sweating and purging.
Although insomnia is a frequent symptom, if a Shaoyin disease patient presents with deep and fine pulse, spontaneous diarrhea, irritability, and inability to sleep, it indicates a critical condition (death). Similarly, in cold damage, fever accompanied by diarrhea, cold limbs, irritability, and inability to lie flat also signifies a critical condition due to the failure of healthy qi and yang qi to recover.
The *Huoren Shu* states: Sweat is the fluid of fire; excessive sweating leads to mental confusion and insomnia. Extreme heat causes unclear spirit and insomnia. Severe purging damages blood; since the Heart governs blood, this leads to insomnia. After recovery, if residual heat remains and yin qi has not recovered, insomnia occurs.
[Taiyang Disease]
In Taiyang disease, if within two to three days the patient cannot lie down but wishes to sit up, there must be palpable obstruction in the epigastrium. With a faint pulse, this indicates cold-fluid retention. Treat with Guizhi Jia Houpo Zizi Tang (Cinnamon Twig Decoction plus Magnolia Bark and Apricot Seed).
In cold damage with floating pulse, if forced sweating via fire therapy causes panic, mania, tossing and turning, treat with Guizhi Qu Shaoyao Jia Shujie Longgu Muli Jiuni Tang (Cinnamon Twig Decoction minus Peony plus Pinellia Prepared, Dragon Bone, and Oyster Shell to Rescue from Reversal).
After purging followed by sweating, if the patient is irritable and unable to sleep during the day but quiet at night, without vomiting, thirst, or exterior syndrome, with a deep and faint pulse and no significant heat, treat with Ganjiang Fuzi Tang (Dried Ginger and Aconite Decoction).
Patients prone to epistaxis should not undergo sweating; if sweated, they may develop sunken temples, tight pulse, fixed gaze, and insomnia (treat with Huangqin Shaoyao Tang).
After cold damage purging, if the patient experiences vexation, abdominal fullness, and restlessness, treat with Zhizi Houpo Tang (Gardenia and Magnolia Bark Decoction).
After sweating, vomiting, or purging, if deficiency vexation leads to insomnia, tossing and turning, and inner regret, treat with Zhizi Chidui Tang (Gardenia and Fermented Soybean Decoction).
After Taiyang disease sweating, if stomach dryness causes insomnia and thirst, give small amounts of water to resolve it.
[Yangming Disease]
Body heat, eye pain, nasal dryness, and inability to lie down, with long pulses at all three positions, indicate Yangming disease involvement. If the patient has difficult urination, alternating difficulty and ease of defecation, slight fever, panting, and vertigo preventing lying down, this indicates dried feces accumulation; use Dachengqi Tang (Major Order the Qi Decoction).
In Yangming disease, with floating-tight pulse, dry throat, bitter taste, abdominal fullness, panting, fever, sweating, aversion to heat rather than cold, and heavy body, if moxibustion is added, the patient will likely feel terrified, irritable, and unable to sleep; use Zhizi Chi Tang (Gardenia and Fermented Soybean Decoction).
[Shaoyin Disease]
In Shaoyin disease, if drowsiness persists for two to three days followed by vexation and inability to sleep, treat primarily with Huanglian Ejiao Tang (Coptis and Donkey-Hide Gelatin Decoction).
Huanglian Ejiao Tang Formula
Huanglian (Coptidis Rhizoma) (4 liang), Huangqin (Scutellariae Radix) (2 liang), Shaoyao (Paeoniae Radix Alba) (2 liang), Ejiao (Colla Corii Asini) (3 liang), Jizihuang (Ovi Gallus Albumen) (2 units).
Boil the first three herbs in five sheng of water to obtain two sheng, strain, dissolve Ejiao, let cool slightly, add Jizihuang, mix well, and take seven he of warm decoction three times daily. (Cheng Wuji notes: Excess yang is cleared with bitter flavors; Coptis and Scutellaria clear heat. Insufficient yin is tonified with sweet flavors; Ovi Gallus Albumen and Colla Corii Asini nourish blood. Sour flavors astringe; Paeoniae Radix Alba astringes yin and drains pathogenic heat. However, if illness persists after taking Ovi Gallus Albumen, it is proposed to add Danggui (Angelicae Sinensis Radix), Renshen (Ginseng Radix), Fuling (Poria), and Baizhu (Atractylodis Macrocephalae Rhizoma) in equal parts to the previous four herbs for immediate effect.)
If Shaoyin disease involves diarrhea and drowsiness, and after six to seven days presents with cough, vomiting, thirst, vexation, and insomnia, use Zhuling Tang (Polyporus Decoction) (see Diarrhea section).
If Shaoyin disease presents with drowsiness, deep-fine pulse, no vexation, desire to vomit, and progresses to spontaneous diarrhea with irritability and insomnia on the fifth or sixth day, it is fatal.
Fever, diarrhea, cold limbs, irritability, and inability to lie flat are fatal signs.
Wu's Commentary:
In Taiyang disease, with floating-numerous pulse, body ache, anhidrosis, irritability, and insomnia, induce sweating for cure.
For Yangming superficial heat with headache, eye pain, body heat, nasal dryness, inability to lie down, and long pulse, use Gegen Jiemi Tang (Kudzu Root Muscle-Releasing Decoction) to induce sweating.
If spontaneous sweating,洪-numerous pulse, interior-exterior heat, vexation, thirst, and dry tongue occur, use Baitu Jia Renshen Tang (White Tiger Plus Ginseng Decoction).
If steaming heat and hard constipation occur, use Tiaowei Chengqi Tang (Regulate the Stomach Order the Qi Decoction) to purge.
If external cold damage has resolved but worsens due to dietary indiscretion, causing stifling sensation, dry retching, dry mouth, groaning, delirium, and insomnia, use Huanglian Jiedu Tang (Coptis Detoxification Decoction).
If interior-exterior severe heat with dry tongue and thirst occurs, use Renshen Baitu Tang combined with Jiedu Tang.
For Shaoyang fever, bitter taste, vexation, insomnia, and wiry-numerous pulse, use Xiaochaihu Tang (Minor Bupleurum Decoction) plus Huanglian and Zhizi. For deficient individuals with insufficient fluids, add Maidong and Suanzaoren.
After Taiyang sweating, if insomnia occurs with floating-numerous pulse, slight heat, vexation, thirst, and dysuria, use Wuling San (Five-Ingredient Powder with Poria). If the pulse is large-numerous, use Renshen Baitu Tang or Zhuye Shigao Tang; do not use Wuling San.
For deficiency vexation and insomnia after sweating/purging, select from Jiawei Wendan Tang, Suanzaoren Tang, Zhizi Wumei Tang, or Zhusha Anshen Wan.
Appendix:
Suanzaoren Tang: Treats deficiency vexation, rushing qi in the chest, and insomnia.
Suanzaoren (Stir-fried), Renshen, Fuling (each 1.5 qian), Guixin (0.5 qian), Shigao (2.5 qian), Zhimu, Gancao (each 1 qian), Shengjiang (3 slices).
Decoct one dose in two zhong of water to one zhong, strain, and take before bed.
Qianjin Liushui Tang: Treats deficiency vexation and insomnia.
Maidong (de-heart), Banxia, Gancao, Huanglian, Yuanzhi, Renshen, Bibi (each 1 qian), Fushen, Suanzaoren (each 1.5 qian), Guixin (0.5 qian), Shengjiang (3 slices), Mi (1 he).
Boil running water in two and a half zhong until crab-eye bubbles appear, ladle ten thousand times to obtain two zhong of water, then decoct herbs to one zhong, strain, and take warm.
Jiawei Wendan Tang: Treats deficiency vexation and insomnia after Taiyang disease, attributed to gallbladder cold.
Banxia (washed), Suanzaoren (stir-fried, each 1.5 qian), Lvzhishi, Chenpi, Gancao (each 1 qian), Renshen (2.5 qian), Fushen (2 qian), Zhuru (one ball), Shengjiang (3 slices).
Decoct in two zhong of water to one zhong, strain, and take warm. If internal heat/vexation, double Huanglian and Maidong. If dry mouth/tongue, remove Banxia, add Maidong, Wuweizi, Tianhuafen. If exterior heat remains, add Ruanmiao Chaihu. If interior deficiency with loose stools, remove Zhishi, add Baizhu and Fuling. If interior excess with severe vexation, add Zhiren.
Suanzaoren Tang (Variant): Treats insomnia day and night after vomiting/purging.
Suanzaoren (stir-fried, 2.5 qian), Maidong, Fushen, Dangguishen (each 2 qian), Gancao, Zhimu, Chuanxiong (each 1.5 qian), Ganjiang (0.3 qian), Shengjiang (3 slices).
Decoction method as above.
Zhizi Wumei Tang
Zhizi, Huangqin, Gancao, Renshen, Maidong (each 1 qian), Chaihu (2 qian), Wumei (2 units), Shengjiang (3 slices), Zhuye (14 leaves).
Decoction method as above.
Huanglian Jiedu Tang: Treats severe heat, dry retching, delirium, groaning, and insomnia.
Huanglian (2.5 qian), Huangqin, Huangbai (each 0.5 liang), Zhizi (4 units).
Decoct in two and a half zhan of water to one and a half zhan, strain, and divide into two doses.