毒中脏腑之气，闭塞不通，上攻三阳颠顶，故痛入脑髓，发晕沉重，不省人事，名真头
痛，旦夕死。急刺颠顶泄毒、药惟破毒清脏为主。毒中脏腑之血，壅瘀不流，上冲三阳头面
肌肉，故肌肉肿胀，目闭耳塞，心胸烦闷，急刺颠顶及其余青筋。药宜清血分，破壅阻为要
（土二、三）。
一人头痛发晕沉重，脉伏，刺颠顶及痧筋，少苏，脉沉实而上鱼际，用土二方。
一妇头面红肿，发热头痛迷闷，脉芤而疾，刺左腿弯三针，血如注，冷服红花膏半杯，
用土三方。
属气则时疼时止，痰涎迷闷，刺手臂，服顺气药为主。属血则大痛不已，昏沉不醒，刺
腿弯，服活血药为主，迟则难救。
一人心中暴痛，痰涎迷闷，两寸沉伏，关尺洪紧，刺痧筋二十针，用石三方，四帖而安
痧毒入肾，腰痛不能俯仰，若误饮热，必烦躁、昏迷、搦搐、舌短、耳聋，垂毙而已。
一妇腰中大痛板硬，误饮热酒，发热烦躁，昏沉痰涌，左尺虚微，右尺洪实，脉兼歇止
，刺血不流，用石四方，腿弯筋现，刺二针血流，再服二帖，痛减。
毒入大、小肠，则小腹大痛不止，形如板硬，绞绞不已，治须分左右二股屈伸为验（土
四）。
夏月不头痛发热，但小腹疼，或心腹俱痛胀痞不能屈伸，此皆暑火流注脏腑，故先小腹
痛，遍及心腹，宜六和汤清解之，或四苓加香薷、木瓜、紫苏和散之，或正气散加黑栀、或
炒盐和阴阳水探吐痰涎可耳。
一少年小腹大痛，每每左卧左足不能屈伸，太阳小肠经痧也。服土四方三帖筋始现，刺
左腿弯二针，用丝七方冷服、愈。
一人小腹大痛，每每右卧右足不能屈伸，阳明大肠经痧也。刺腿弯青筋四针血流不愈，
用竹八方冷服，半夜痧退而安。
毒邪侵入脏腑之气，导致气机闭塞不通，向上攻冲至三阳经的颠顶部位，因此疼痛深入脑髓，出现头晕沉重、神志不清的症状，这种病症称为真头痛，若不及时救治，早晚即可致死。此时应急速针刺颠顶以泄出毒邪，用药应以破除毒邪、清解脏腑为主。
毒邪侵入脏腑之血，导致血液壅滞瘀阻而不流通，向上冲犯三阳经及头面肌肉，因此出现肌肉肿胀、眼睛闭合、耳朵堵塞、心胸烦闷等症状，应急速针刺颠顶以及其余显现的青筋（痧筋）。用药宜清解血分，以破除壅滞阻塞为关键。（参考方剂：土二方、土三方）
有一人头痛、头晕且感觉沉重，脉象伏匿不起，针刺颠顶及痧筋后，症状稍见缓解，但脉象转为沉实且上鱼际，使用土二方治疗。
有一位妇女头面部红肿，发热、头痛且意识迷蒙，脉象芤而疾速，针刺左腿弯处三针，出血如注，冷服红花膏半杯，随后使用土三方治疗。
若病属气分，则疼痛时作时止，伴有痰涎迷蒙，应针刺手臂，服用顺气药物为主。若病属血分，则剧烈疼痛不止，昏沉不醒，应针刺腿弯处，服用活血药物为主，若延误时机则难以救治。
有一人心脏突发剧痛，痰涎迷蒙，两手寸脉沉伏，关脉和尺脉洪大紧实，针刺痧筋二十针，使用石三方，服用四帖后病情安定。
痧毒侵入肾脏，导致腰痛无法俯仰，如果误饮热性饮品，必然会出现烦躁、昏迷、抽搐、舌体短缩、耳聋等症状，濒临死亡。
有一位妇女腰部剧烈疼痛且板硬，误饮热酒后，出现发热烦躁、昏沉痰涌，左尺脉虚微，右尺脉洪实，脉象兼有歇止，刺络放血不出血，使用石四方；待腿弯处青筋显现，再刺两针，血流出来，随后再服用两帖药，疼痛减轻。
毒邪侵入大肠和小肠，则小腹部剧烈疼痛不止，外形如同木板般坚硬，绞痛不停，治疗需观察左右大腿屈伸情况作为验证标准（参考方剂：土四方）。
夏季若不头痛发热，仅小腹痛，或者心腹都疼痛胀满痞塞不能屈伸，这都是暑火流注于脏腑所致，所以先从小腹痛开始，遍及心腹，宜用六和汤清解，或用四苓散加香薷、木瓜、紫苏调和发散，或用正气散加黑栀子，或炒盐和阴阳水探吐痰涎即可。
有一位少年小腹部剧烈疼痛，每每左侧卧时左足不能屈伸，这是太阳小肠经的痧症。服用土四方三帖后青筋才显现，针刺左腿弯处两针，使用丝七方冷服，痊愈。
有一位小腹部剧烈疼痛，每每右侧卧时右足不能屈伸，这是阳明大肠经的痧症。针刺腿弯处青筋四针，出血后仍未痊愈，使用竹八方冷服，半夜时痧退而病情安定。
Poisonous pathogens invade the Qi of the Zang-Fu organs, causing obstruction and blockage. They attack upwards to the vertex (Dian Ding) where the Three Yang meridians converge, thus causing pain penetrating into the brain marrow, accompanied by dizziness, heaviness, and loss of consciousness. This condition is named True Headache (Zhen Tou Tong). If not treated urgently, death may occur within a day or two. Emergency acupuncture at the vertex should be performed to drain the poison. The medicinal prescription should primarily focus on breaking down the poison and clearing the Zang-Fu organs.
If poisonous pathogens invade the Blood of the Zang-Fu organs, causing stagnation and stasis with impaired flow, they rush upwards to the Three Yang meridians and the muscles of the head and face. Consequently, muscle swelling, closed eyes, blocked ears, and chest/heart irritability occur. Emergency acupuncture at the vertex and other visible blue veins (Sha Jin) should be performed. Medicinal treatment should clear the Blood level, prioritizing the resolution of stagnation and obstruction. (Refer to Formulas: Tu Er Fang, Tu San Fang).
A patient suffered from headache, dizziness, and heaviness, with a deep-hidden pulse. After acupuncture at the vertex and Sha Jin, symptoms slightly improved, but the pulse became deep, solid, and extended to the Yu Ji area. Formula Tu Er Fang was administered.
A female patient presented with redness and swelling of the head and face, fever, headache, and mental confusion. Her pulse was hollow (Kou) and rapid. Three needles were inserted at the popliteal crease of the left leg, resulting in profuse bleeding. Half a cup of Hong Hua Gao (Safflower Paste) was taken cold, followed by the administration of Formula Tu San Fang.
If the pathology belongs to Qi, the pain comes and goes intermittently, accompanied by phlegm-saliva misting the mind. Acupuncture should be applied to the arms, and Qi-regulating medicines should be the primary treatment. If the pathology belongs to Blood, severe unceasing pain occurs with stupor and unconsciousness. Acupuncture should be applied to the popliteal region, and blood-invigorating medicines should be the primary treatment. Delayed treatment makes rescue difficult.
A patient experienced sudden severe pain in the heart/chest, with phlegm-saliva obscuring consciousness. The Cun pulses of both hands were deep and hidden, while the Guan and Chi pulses were surging and tight. Twenty needles were inserted into the Sha Jin points, and Formula Shi San Fang was used. After four doses, the condition stabilized.
When Sha poison enters the Kidney, it causes lower back pain preventing flexion and extension. If hot drinks are mistakenly consumed, it will inevitably lead to restlessness, coma, convulsions, short tongue, deafness, and impending death.
A female patient suffered from severe, board-like stiffness in the waist. After mistakenly drinking hot wine, she developed fever, restlessness, stupor, and surging phlegm. The Left Chi pulse was deficient and faint, while the Right Chi pulse was surging and solid, with intermittent interruptions. Initial bloodletting yielded no blood. Formula Shi Si Fang was administered. When the veins appeared at the popliteal crease, two needles were inserted, allowing blood to flow. Two additional doses were taken, reducing the pain.
When poison enters the Large Intestine and Small Intestine, severe, unceasing lower abdominal pain occurs, with the abdomen feeling hard like a board and twisting pain persisting. Treatment verification involves observing flexion and extension of the thighs on either side (refer to Formula Tu Si Fang).
In summer, if there is no headache or fever, but only lower abdominal pain, or if both the heart and abdomen are painful, distended, and stiff preventing movement, this is due to Summer-heat Fire flowing into the Zang-Fu organs. Thus, lower abdominal pain starts first and spreads to the heart and abdomen. Liu He Tang should be used for clearing and resolving, or Si Ling San added with Xiang Ru, Mu Gua, and Zi Su for harmonizing and dispersing. Alternatively, Zheng Qi San added with Hei Zhi Zi, or a mixture of fried salt water and Yin-Yang water can be used to induce vomiting to expel phlegm-saliva.
A young male suffered from severe lower abdominal pain, unable to flex his left leg when lying on his left side. This was Sha disease of the Taiyang Small Intestine Meridian. After three doses of Tu Si Fang, the veins appeared. Two needles were inserted at the left popliteal crease, and Si Qi Fang was taken cold, leading to recovery.
Another patient suffered from severe lower abdominal pain, unable to flex his right leg when lying on his right side. This was Sha disease of the Yangming Large Intestine Meridian. Four needles were inserted into the blue veins at the popliteal crease; although blood flowed, the condition did not improve. Zhu Ba Fang was taken cold. By midnight, the Sha pathogen receded, and the patient stabilized.