牛痘法全在养苗,此苗始自外洋,嗣后以人传人,贵乎连绵不绝。予既于洋行会馆设局
,夏月以八日为一期,春、秋、冬以九日为期,周而复始,来种者风雨勿改。而洋行好善诸
公,复醵金生息,自四月至九月来种者,酌以果金与取浆之人。其所以设果金者,盖当盛夏
溽暑之时,即平日深信者,亦多拘执而不肯来,痘不种则浆无从取,浆不取则苗无以继,今
既设果金,俾来者孩童既获安全,而贫乏者亦不无小补,于是种痘者源源而来,而佳苗乃绵
绵弗绝,行之既之,人咸知牛痘之法,虽盛暑亦无碍矣。
父母爱子之心,人人皆同。粤东地势卑湿,不无疯疾,来求种痘者,恐一同混杂,误取
其浆,传之无疾小儿,为害不浅。以此告知洋行诸公,呈请有司派令养济院认识疯疾之人,
具结存案,逢期到局伺候。凡来者先令认过,然后取苗,自无贻误。
其法不论春夏秋冬,随时皆可,不拣天气,不择良辰,不避风,不禁忌,不分男女,不
拘大小,自小儿生百日后,但现下无疮癞、无瘰 、无胎毒及皮肤血热疳积诸疾病,便可随
时引种。
牛痘灌浆满足,总在八九日,故种痘之期,大都以八九日为率。太早则浆无力,太迟则
苗老无功。至期,于先一期所种浆水满足之孩童,择其痘顶不尖、脚不斜、不皱不黄、不暗
、不破,要如红线围缠,收束紧实,色若珍珠宝光者;又察此童现下无疮癞、瘰 、胎毒、
皮肤、血热、疳积、疾病等症者,是谓佳苗。若其痘色淡白,暗而无宝光,顶虽平而脚斜似
松,中央无一点焦硬者,不宜用。
苗既佳矣,取苗时,用刀尖向其痘面四围轻轻剔破,将痘面中央一点焦硬小靥微揭,其
浆清亮者可用。若见浆水浊白或黄,即使刀尖两三次点去浊浆,俟其流出清浆如圆珠,粒粒
不流散者为贵,好浆一粒,可种数人。
种痘时,孩童衣衫两袖卷贴膊上,用小绳横穿两袖,退出紧紧,令其臂露出,虽寒天不
忌。男先左,女先右。种痘种左手执定孩童之臂,勿令伸缩,右手将刀尖点取佳苗,向两臂
消烁、清冷渊穴,每臂每穴,各种一颗。如孩童年至八九岁以上,日 腥腻五味。恐或有后
天之毒,则于两穴上下相连之处中间,更各种一颗,不宜出四颗,六颗数外。
其刺法,用刀不宜直竖,宜轻巧,将点苗刀尖,轻轻平刺皮膜如一纸之薄,刺处约宽一
分,以微见血为度。将刀尖之浆辗转 拭,同其微血注于所刺穴中,使浆与血调和,其气达
于三焦之经,自然取效。断不宜手重,恐深刺入肉,出血咯多,反将苗浆带出,不能成功。
将衣衫垂下,不必用绸包裹束扎,反令血气不行。贴身之衣,宜用柔软丝绸,若衣服浆洗粗
硬者,恐致擦损。
牛痘接种法的关键在于培育优质的“苗”(指牛痘浆液),这种苗最初源自海外,后来通过人与人之间的传播延续下来,贵在连绵不断、生生不息。我在洋行会馆设立了接种局,夏季以八天为一个周期,春、秋、冬三季以九天为一个周期,循环往复,前来接种的人无论风雨都不改变时间。而洋行中乐善好施的各位先生,又集资生息,从四月到九月期间前来接种的人,酌情给予水果津贴给取浆的人。之所以设立水果津贴,是因为在盛夏酷暑之时,即使是平日深信不疑的人,也大多因拘泥固执而不愿前来;如果不种痘,就无法取得浆液;如果不取浆液,种苗就无法继续传承。现在既然设立了水果津贴,使得前来的孩童既能获得安全保障,贫困者也能得到些许补助,于是种痘的人源源不断地到来,优良的种苗也就绵绵不绝地传承下去。实行久了之后,人们都知道了牛痘的方法,即使是盛暑天气也没有妨碍了。
父母爱护子女的心,人人都是相同的。广东东部地势低洼潮湿,难免有疯疾(如狂犬病或某些传染性皮肤病)流行,前来求种痘的人,恐怕会混杂在一起,误取了患有疯疾者的浆液,传给没有疾病的孩童,危害不小。因此告知洋行的各位先生,呈请官府派遣养济院中认识疯疾症状的人员,立下保证书存档,定期到局里待命。凡是来接种的人,先让他们经过这些专业人员辨认确认,然后才取苗接种,自然就不会贻误。
这种方法不论春夏秋冬,随时都可以进行,不挑选天气,不选择良辰吉日,不避讳风邪,不设禁忌,不分男女老少,只要孩童出生满一百天后,当下没有疮癞、瘰疬、胎毒以及皮肤血热、疳积等各种疾病,就可以随时引种。
牛痘灌浆成熟饱满,总是在第八或第九天,所以种痘的时间,大都以八九天为标准。太早则浆液力量不足,太迟则种苗老化失去功效。到了日期,要在上一期所种、浆水已满足的孩童中,挑选那些痘顶不尖、根部不斜、不皱缩不发黄、不晦暗、不破损,要像红线围缠一样,收束紧实,色泽像珍珠宝石般光亮的人;还要观察这个孩童当下没有疮癞、瘰疬、胎毒、皮肤问题、血热、疳积、疾病等症状,这叫做佳苗。如果痘色淡白,晦暗而没有宝光,痘顶虽然平但根部松散似松垮,中央没有一点焦硬感的,不宜使用。
种苗既已选好,取苗时,用刀尖向痘面四周轻轻剔破,将痘面中央那一点焦硬的小痂微微揭开,其中浆液清亮的可以使用。如果见到浆液浊白或发黄,即使刀尖点去两三次浊浆,等到流出清亮如圆珠、颗粒分明不流散的浆液才算珍贵,好的一粒浆液可以接种几个人。
种痘时,孩童的衣服袖子卷起贴在胳膊上,用小绳子横穿两袖,退出来紧紧绑住,让手臂露出来,即使是寒冷的天气也不忌讳。男子先种左手,女子先种右手。种痘时,左手固定孩童的手臂,不要让他伸缩,右手拿刀尖点取佳苗,向两臂的消烁穴、清冷渊穴接种,每只手臂每个穴位,各种一颗。如果孩童年龄达到八九岁以上,平时吃腥腻五味食物较多,恐怕会有后天的毒素,那么就在两个穴位上下相连处的中间,再各种一颗,但不宜超过四颗,六颗以外就不合适了。
其刺法,用刀不宜直竖,宜轻巧,将点苗刀尖,轻轻平刺入皮膜,薄如一纸,刺处约宽一分,以微微见血为度。将刀尖上的浆液辗转擦拭,同其微血注入所刺的穴位中,使浆与血调和,其气达于三焦之经,自然见效。绝不应该手重,恐怕深刺入肉,出血过多,反而将苗浆带出,不能成功。
将衣衫垂下,不必用绸包裹束扎,反而会让气血运行不畅。贴身衣服,宜用柔软丝绸,如果衣服浆洗得粗硬,恐怕会导致擦损伤口。
The method of cowpox vaccination relies entirely on nurturing the "seed" (referring to the cowpox lymph/vaccine material). This seed originated from overseas and was subsequently transmitted from person to person, with the key being its continuous and unbroken propagation. I established a clinic at the foreign trade firm's guild hall. In summer, each cycle lasted eight days; in spring, autumn, and winter, each cycle lasted nine days. These cycles repeated continuously, and appointments for vaccination were not changed due to wind or rain. Furthermore, the benevolent gentlemen of the foreign trade firms pooled funds to generate interest. From April to September, those coming for vaccination were given fruit allowances for the persons collecting the lymph. The reason for establishing this allowance was that during the intense heat of midsummer, even those who firmly believed in the practice often hesitated and refused to come. If no vaccination was performed, no lymph could be collected; if no lymph was collected, the seed could not be continued. Now that the fruit allowance has been established, children who come receive safety guarantees, and the poor receive some financial relief. Consequently, people seeking vaccination came in a steady stream, and excellent seeds were propagated without interruption. After the practice had been carried out for some time, everyone became aware of the cowpox method, and even in the height of summer, it posed no hindrance.
The love parents have for their children is universal. In eastern Guangdong, the terrain is low and damp, making it prone to madness diseases (such as rabies or certain infectious dermatological conditions). Those coming for vaccination might mix together, risking the accidental collection of lymph from those suffering from madness, which would then be transmitted to healthy children, causing significant harm. Therefore, I informed the gentlemen of the foreign trade firms and petitioned the authorities to dispatch personnel from the Charity Hospital (Yangji Yuan) who were skilled in recognizing symptoms of madness. These personnel were required to submit written guarantees and be on standby at the clinic during scheduled periods. All applicants were first examined by these specialists before lymph was collected, ensuring no errors occurred.
This method can be applied at any time regardless of the season, without selecting auspicious weather or favorable dates, avoiding wind, or observing taboos. It applies to both males and females of all ages. As long as the child is over one hundred days old and currently free from sores, leprosy-like conditions, scrofula (Luo Li, 瘰疬), congenital toxins, skin blood-heat, malnutrition syndromes (Gan Ji, 疳积), and other diseases, vaccination can be performed at any time.
Cowpox pustules typically reach full maturity around the eighth or ninth day. Therefore, the timing for vaccination generally follows this eight-to-nine-day standard. Vaccinating too early results in weak lymph; vaccinating too late renders the seed ineffective due to aging. On the appointed day, select children from the previous cycle whose pustules are fully filled with lymph. Choose those whose pustule tops are not pointed, bases are not slanted, and who show no wrinkling, yellowing, dullness, or rupture. The ideal pustule should resemble a tight red thread encircling it, gathered firmly, with a luster like precious pearls or gems. Additionally, ensure the child currently has no sores, scrofula, congenital toxins, skin issues, blood-heat, Gan Ji, or other diseases. This is considered an excellent seed. If the pustule color is pale white, dull without luster, the top is flat but the base is loose, and there is no hard, scorched center, it should not be used.
Once the seed is selected, when collecting the lymph, gently scrape the perimeter of the pustule surface with the tip of a knife. Slightly lift the small, hard scab in the center of the pustule. Lymph that is clear and bright is usable. If the lymph appears turbid, white, or yellow, use the knife tip to remove the turbid lymph two or three times until clear lymph flows out like round beads, distinct and not dispersing. This is considered high-quality; one good drop of lymph can vaccinate several people.
During vaccination, roll up the child's sleeves and tie them tightly against the upper arms with a small string to expose the forearms, even in cold weather. For boys, start with the left arm; for girls, start with the right. With the left hand, hold the child's arm steady to prevent movement. With the right hand, use the knife tip to collect the excellent seed and inoculate it into the Xiaoshuo (Xiaoshuo acupoint) and Qinglengyuan (Qinglengyuan acupoint) on both arms. One pustule is inoculated per acupoint per arm. If the child is eight or nine years old or older and consumes a diet rich in fish, meat, greasy foods, and strong flavors, potentially accumulating post-natal toxins, inoculate an additional pustule in the middle between the two upper and lower connected points. However, do not exceed four pustules total; six or more is inappropriate.
The puncturing technique requires the knife not to be held vertically but handled lightly. Gently pierce the skin membrane horizontally with the knife tip, as thin as a sheet of paper. The wound width should be about one fen (approx. 3.3 mm), stopping when slight bleeding occurs. Roll the knife tip to wipe the lymph, mixing it with the slight blood and injecting it into the punctured acupoint. This allows the lymph and blood to harmonize, and the qi reaches the Sanjiao (Triple Burner) meridians, naturally producing efficacy. Do not apply heavy pressure; deep puncturing into the muscle may cause excessive bleeding, which could expel the vaccine material and prevent success.
Let the clothes hang down freely; do not wrap or bind them with silk, as this may obstruct the flow of qi and blood. Undergarments should be made of soft silk. If clothes are stiffened by starch or coarse washing, they may rub against and damage the wounds.