分气虚、血虚，补之。气虚，用参、术、苓、甘加解毒药；血虚，四物加解毒药，酒炒黄连是解毒药，但见红点便
忌，升麻葛根汤发得表虚也。吐泻少食为里实，里实而补，则结痈陷伏靥灰白为表虚，或用烧人中黄子和方，黑陷
甚者烧人屎，红活锭凸为表实，表实复用表药，则溃烂不结痂，吐泻、陷伏二者俱见，为表里俱虚。痘疮初出或未出
时，见人有患者宜预此药，多者可少，重者可轻，其方用丝瓜近蒂者三寸，连瓜子皮都烧灰存性，为末，沙糖拌干吃，
入朱砂未亦可。解痘疮毒方，丝瓜、升麻、酒芍药、生甘草、棠 、黑豆、犀角、赤小豆。又方，解痘疮已出未出
皆可用，朱砂为末，蜜水调服，多可减少，少者可无。小儿豆疮泄泻发渴，切不可与蜜水、西瓜、红柿生冷之物，可
进木香散，陈文中小儿方内求之。疮疹未发出证的，以胭脂涂眼眶不生痘疮。痘疮脓溃沾衣者，可用腊月黄牛粪烧
灰挹睡，免生痘疮痈。头面豆痂剥去脓血出，以真酥油润之，免成癣。痘斑疮，心躁，眠不安，升麻汁绵蘸洗拭。
痘疮气虚而发不出者，黄 、人参、酒芍药、当归、川芎、
酒红花，如豆许，木香、紫草。气实痰郁而不发者，苍术、白芷、防风、升麻、黄芩、赤芍药、连翘、当归须。
血热而发得势甚者，下焦成疮，无皮口渴，天花粉、黄芩、芍药、葛根、甘草、石膏、滑石。血气俱弱而黑陷者，酒
芍药、人参、黄 、白芷、木香、桂皮、川芎、当归。血为湿，头靥而灰白者，红花、苏木、白术、苍术、芍药、当
归、川芎，加酒少许。发后为外恶气所伤而倒靥，人参、芍药、连翘、黄 梢、甘草梢、白芷、酒当归、川芍、木香
少许。凡痘疮，须分人之清浊，就形气上取勇怯。黑陷二种气虚而不能尽出者，用酒炒黄 、人参、酒紫草。颜色
正，如上法欲成就却淡；色不正者，用芎，归，芍药、红花酒之类，欲成就却紫色属热，用升、葛、芩、连、桂、翘之
类。甚者，犀角屑大解痘毒。炉灰白色，静者、怯者作寒看；齐者、勇者、躁者、 发者作热看。全白色将靥时如豆
壳，盖因初起时饮水过多，其靥不齐，俗呼为倒靥，不妨，但服实表之剂。消息他大小便，如大便秘，则通大便；如小
便闭，则通小便。有初起烦躁谵语，狂渴引饮，若饮水，则后来靥不齐，急以凉药解其标，如益元散之类亦可用。痒
塌者，于形色脉上分虚实。实，则脉有力气壮；虚，则脉无力气怯。虚痒，以实表之剂加凉血药；实痒或大便秘者，以
大黄寒凉药少与之，下其结粪。气怯轻者，用淡蜜水调滑石末，以羽润疮上。疏则无毒，密则有毒，用凉药解之，虽
十数帖亦不妨，后无害眼之患。干者，便用退火，湿者，便用泻湿。退火，用轻剂，荆芥、升麻、甘、葛之类；泻湿乃
肌表间湿，用风药，白芷、防风之类。痘疮伤眼，必用山栀、决明、赤芍药、当归须、黄芩、黄连、防风、连翘、升
麻、桔梗，为末，作小剂调服。如无光，过百日后气血复，
当自明。痘痈多是表实、血热所成，分上下治，一日不可缓也。成脓，必用出凉药为主，赤芍药、甘草节、连翘、桔
梗，上引用升麻、葛根，下引用槟榔、牛膝，助以贝母、忍冬草、白芷、栝蒌之类。大便燥用大黄；发热用黄芩、黄
柏。痘疮黑属血热，凉血为主；白属气虚，补气为主。中黑陷而外白，起得迟，则相兼而治。初起时，自汗不妨，盖
湿热熏蒸而起故也。痘分气、血、虚、实，以日子守之，多带气血不足处。虚则黄 ，生血活血之剂助之，略佐以风
药；实则白芍药、黄芩为君，白芷、连翘佐之。若属寒者，陈氏方亦可用。已发未发并与参苏饮为当。调解之法，
大率活血调气，安表和中，轻清消毒，温凉之剂二者得兼而已，温如当归、黄 、木香辈；凉如前胡、甘葛、升麻辈。
佐之以川芎、芍药、枳壳、桔梗、木通、紫草、甘草之属。初起时自汗不妨，盖湿热熏蒸而然。痘痈敷药∶贝母 南
星僵蚕 天花粉 白芷 草乌 大黄 猪牙皂角等分 寒水石倍用 上为末，醋调敷。一男子，年二十余患痘疮，
靥谢后，忽口噤不开，四肢强直，不能舒屈，时绕脐痛，痛一阵则冷汗出如雨，痛定则汗止，时止时作，其脉弦紧而
急，如直 状，询知此子极劳苦，意其因劳倦伤血，且山居多风寒乘虚而感，之后，因痘出其血又虚，当用温药养血，
辛凉散风，遂以当归身、白芍药为君，以川芎、青皮、钩藤为臣，白术、陈皮为佐，甘草、桂皮、南木香、黄芩为使，
加以红花少许，煎服而愈。予从子，六七岁时出痘，身热，微渴，自利，医用木香散加丁香十粒。予观其出迟，固因自
利而气弱，然其所下皆臭滞，盖因热蒸而下，恐未必寒，急止之，已投一帖矣，与黄连解毒汤加白术，近十帖以解之，
利止，痘亦出。其肌常微热，手足生肿，又与凉补，一月
安。一人年十七，出痘发热而昏倦甚，脉大而似数，与参、术、 、归、陈皮，大料浓汤饮之，二十帖痘出，又与
二十帖，则脓胞成，身无全肤，或用陈氏本方与之，予曰但虚无寒，又与前方，至六十帖而安。
辨别气虚与血虚，进行补益。气虚者，用人参、白术、茯苓、甘草加入解毒药物；血虚者，用四物汤加入解毒药物，酒炒黄连是解毒药，但见到红点便需忌用，因为升麻葛根汤会使表虚更甚。呕吐腹泻、食欲不振属于里实，若对里实证进行补益，则会导致痘疮结痂时凹陷伏陷、颜色灰白，这属于表虚，或者使用烧制的人中黄子和方剂，黑陷严重的用烧过的人粪。痘色红活、隆起坚实属于表实，若表实证再次使用发表药物，则会导致溃烂不结痂。呕吐腹泻与痘疮凹陷伏陷同时出现，属于表里俱虚。痘疮刚发出或尚未发出时，见有患者，宜预先服用此药，病情重者可减量，轻者可加重剂量。其方用靠近瓜蒂的丝瓜三寸，连同瓜子皮一起烧成存性炭，研为细末，拌干沙糖食用，加入朱砂粉末亦可。解痘疮毒的方剂：丝瓜、升麻、酒炒芍药、生甘草、棠梨、黑豆、犀角、赤小豆。另一个方剂，解痘疮毒，无论痘疮已出或未出皆可使用，朱砂研为细末，蜜水调服，病情重者多服，轻者少服，轻症可不服。小儿痘疮伴泄泻、口渴，切不可给予蜜水、西瓜、红柿等生冷之物，可进服木香散，可在陈文中小儿方剂中查找。疮疹尚未发出显现证候时，可用胭脂涂抹眼眶，以防生出痘疮。痘疮脓液溃破沾湿衣物者，可用腊月黄牛粪烧成的灰涂抹睡眠处，以免生出痘疮痈。头面部痘痂剥落后脓血流出，用真酥油滋润，以免形成癣疾。痘斑疮，心中烦躁，睡眠不安，用升麻汁浸绵蘸拭清洗。痘疮因气虚而发不出来者，用黄芪、人参、酒炒芍药、当归、川芎、酒红花（如豆粒大小）、木香、紫草。因气实痰郁而不发者，用苍术、白芷、防风、升麻、黄芩、赤芍药、连翘、当归须。血热而痘势猖獗严重者，下焦成疮，无皮且口渴，用天花粉、黄芩、芍药、葛根、甘草、石膏、滑石。气血俱弱而痘色黑陷者，用酒炒芍药、人参、黄芪、白芷、木香、桂皮、川芎、当归。血被湿邪所困，头面结痂呈灰白色者，用红花、苏木、白术、苍术、芍药、当归、川芎，加少许酒。痘疮发出后受外邪恶气损伤而倒靥（痘疮回缩），用人参、芍药、连翘、黄芩梢、甘草梢、白芷、酒当归、川芎、少许木香。凡是痘疮，必须分辨患者的清浊体质，根据形体气势判断勇怯。黑陷两种情况属气虚而不能完全发出者，用酒炒黄芪、人参、酒紫草。痘色正常，按上述方法欲使其成熟却颜色淡；痘色不正者，用川芎、当归、芍药、红花酒之类；欲使其成熟却呈紫色属热，用升麻、葛根、黄芩、黄连、桂枝、连翘之类。严重者，用犀角屑大力解除痘毒。炉灰白色，安静者、怯弱者视为寒证；整齐者、勇敢者、烦躁者、发热者视为热证。全白色在将结痂时像豆壳一样，这是因为初起时饮水过多，导致结痂不齐，俗称倒靥，不妨碍，只需服用固表之剂。观察其大小便情况，如大便秘结，则通大便；如小便闭塞，则通小便。有初起时烦躁谵语，狂渴引饮，如果饮水，则后来结痂不齐，急以凉药解除标证，如益元散之类也可使用。瘙痒塌陷者，从形色脉象上分辨虚实。实证，则脉有力、气壮；虚证，则脉无力、气怯。虚痒，用固表之剂加入凉血药；实痒或大便秘结者，少量给予大黄等寒凉药，攻下结粪。气怯轻微者，用淡蜜水调滑石末，用羽毛润敷疮上。稀疏则无毒，密集则有毒素，用凉药解除，即使服用十几帖也无妨，之后没有伤眼的祸患。干燥者，即用退火之法；湿润者，即用泻湿之法。退火，用轻剂，荆芥、升麻、甘草、葛根之类；泻湿乃肌表间的湿气，用风药，白芷、防风之类。痘疮伤眼，必用山栀、决明子、赤芍药、当归须、黄芩、黄连、防风、连翘、升麻、桔梗，研为细末，作小剂量调服。若无光泽，过百日后气血恢复，自然会明亮。痘痈多是表实、血热所成，分上下治疗，一日不可迟缓。成脓期，必用凉药为主，赤芍药、甘草节、连翘、桔梗，上行引用升麻、葛根，下行引用槟榔、牛膝，辅助以贝母、忍冬草、白芷、栝蒌之类。大便燥结用大黄；发热用黄芩、黄柏。痘疮黑色属血热，以凉血为主；白色属气虚，以补气为主。中间黑陷而外部白色，起发迟，则兼治。初起时，自汗不妨碍，因为是湿热熏蒸而起的原因。痘疮分气、血、虚、实，以日子来守候观察，多带有气血不足的情况。虚证则用黄芪，用生血活血的药剂辅助它，略微佐以风药；实证则以白芍药、黄芩为君药，白芷、连翘为佐药。若属寒证，陈氏的方剂也可使用。痘疮已发未发都适宜用参苏饮。调解的方法，大体是活血调气，安表和胃，轻清消毒，温凉两方面的药剂兼顾而已，温性的如当归、黄芪、木香之类；凉性的如前胡、甘草、葛根、升麻之类。佐以川芎、芍药、枳壳、桔梗、木通、紫草、甘草之类的药物。初起时自汗不妨碍，因为是湿热熏蒸所致。痘痈敷药：贝母、南星、僵蚕、天花粉、白芷、草乌、大黄、猪牙皂角等分，寒水石加倍使用，以上研为细末，醋调敷。一男子，二十多岁患痘疮，结痂脱落后，突然口噤不开，四肢强直，不能舒展弯曲，时常绕脐疼痛，痛一阵则冷汗如雨下，痛定则汗止，时停时作，其脉弦紧而急，像弓弦一样，询问得知此人极度劳苦，推测是因劳倦伤血，且居住山区风寒乘虚而入感邪，之后因痘疮发出其血又虚，应当用温药养血，辛凉散风，遂用当归身、白芍药为君药，川芎、青皮、钩藤为臣药，白术、陈皮为佐药，甘草、桂皮、南木香、黄芩为使药，加上少许红花，煎服而愈。我的侄子，六七岁时出痘，身热，微渴，自利（腹泻），医生用木香散加丁香十粒。我看他出痘迟，固然因为腹泻而气弱，但他所下的粪便皆臭滞，是因为热蒸而下，恐怕未必是寒证，急忙制止用药，已经投了一帖药了，改用黄连解毒汤加白术，将近十帖以解除热毒，腹泻停止，痘疮也发出了。他的肌肤常微热，手足生肿，又给予凉补之剂，一个月痊愈。一人十七岁，出痘发热且昏倦严重，脉大而似数，给予人参、白术、黄芪、当归、陈皮，大剂量浓汤饮用，二十帖痘疮发出，又给予二十帖，则脓疱形成，身上没有完好的皮肤，有人用陈氏的本方给他，我说只要没有虚无寒象，又给予前方，至六十帖而痊愈。
Differentiate between Qi deficiency and Blood deficiency, and tonify them. For Qi deficiency, use Ginseng Radix et Rhizoma (Renshen), Atractylodis Macrocephalae Rhizoma (Baizhu), Poria (Fuling), and Glycyrrhizae Radix et Rhizoma (Gancao) added with detoxifying herbs; for Blood deficiency, use Siwu Tang (Four Substances Decoction) added with detoxifying herbs. Wine-fried Coptidis Rhizoma (Huanglian) is a detoxifying herb, but it should be avoided when red spots appear, as Shengma Gegen Tang (Cimicifugae and Puerariae Decoction) may exacerbate exterior deficiency. Vomiting, diarrhea, and poor appetite indicate interior excess; tonifying interior excess will cause the pustules to collapse, become flat, and turn grayish-white, indicating exterior deficiency. Alternatively, use Shaorenzhonghuang Zi Fang (Burning Human Excrement Ash Formula) or burned human feces for severe black depression. Red, vibrant, and convex pustules indicate exterior excess; reusing exterior-releasing herbs for exterior excess will lead to ulceration without scabbing. The simultaneous presence of vomiting/diarrhea and collapsed pustules indicates both exterior and interior deficiency. When pustules are just emerging or have not yet emerged, if one encounters a patient, this medicine should be taken prophylactically: reduce the dose for severe cases and increase it for mild ones. The formula uses three cun of loofah near the stem, including seeds and skin, burned to charcoal while retaining its nature, ground into powder, mixed with dry rock sugar for oral consumption, or mixed with Cinnabar (Zhusha) powder. A formula to resolve toxin from smallpox includes Luffae Fructus (Sigua), Cimicifugae Rhizoma (Shengma), wine-fried Paeoniae Radix Alba (Baishao), raw Glycyrrhizae Radix et Rhizoma (Sheng Gancao), Pyri Fructus (Tangli), Sojae Semen Nigrum (Heidou), Rhinocerotis Cornu (Xijiao), and Phaseoli Semen Rubrum (Chixiaodou). Another formula for resolving smallpox toxin can be used whether the rash has emerged or not: grind Cinnabar (Zhusha) into powder, mix with honey water for administration; take more for severe cases, less for mild, or none at all. For children with smallpox accompanied by diarrhea and thirst, absolutely avoid honey water, watermelon, persimmons, and other cold/raw foods. Instead, administer Muxiang San (Aucklandia Powder), which can be found in Chen's pediatric formulas. For rashes that have not yet manifested symptoms, apply carmine to the eye orbits to prevent pustule formation. If pus from smallpox sores stains clothing, apply ash from yellow cow dung burned in the twelfth lunar month to the sleeping area to prevent carbuncles. If head and face scabs peel off with pus and blood, lubricate with pure butter to prevent tinea. For smallpox spots with mental restlessness and sleep disturbance, wash and wipe with juice of Cimicifugae Rhizoma (Shengma). For smallpox failing to emerge due to Qi deficiency, use Astragali Radix (Huangqi), Ginseng Radix et Rhizoma (Renshen), wine-fried Paeoniae Radix (Baishao), Angelicae Sinensis Radix (Danggui), Ligustici Chuanxiong Rhizoma (Chuanxiong), Safflower (Honghua) fried in wine (size of a bean), Aucklandiae Radix (Muxiang), and Lithospermi Radix (Zicao). For failure to emerge due to Qi excess and phlegm stagnation, use Atractylodis Rhizoma (Cangzhu), Angelicae Dahuricae Radix (Baizhi), Saposhnikoviae Radix (Fangfeng), Cimicifugae Rhizoma (Shengma), Scutellariae Radix (Huangqin), Paeoniae Radix Rubra (Chishao), Forsythiae Fructus (Lianqiao), and Angelicae Sinensis Radix radix (Danggui Xu). For severe eruption due to Blood heat, with lower jiao sores, lack of skin, and thirst, use Trichosanthis Radix (Tianhuafen), Scutellariae Radix (Huangqin), Paeoniae Radix (Shaoyao), Puerariae Radix (Gegen), Glycyrrhizae Radix et Rhizoma (Gancao), Gypsum Fibrosum (Shigao), and Talcum (Huashi). For Black depression due to joint Qi and Blood weakness, use wine-fried Paeoniae Radix (Jiu Shaoyao), Ginseng Radix et Rhizoma (Renshen), Astragali Radix (Huangqi), Angelicae Dahuricae Radix (Baizhi), Aucklandiae Radix (Muxiang), Cinnamomi Cortex (Guipi), Ligustici Chuanxiong Rhizoma (Chuanxiong), and Angelicae Sinensis Radix (Danggui). For Blood trapped by dampness with grayish-white head/face scabs, use Safflower (Honghua), Sappan Lignum (Sumu), Atractylodis Macrocephalae Rhizoma (Baizhu), Atractylodis Rhizoma (Cangzhu), Paeoniae Radix (Shaoyao), Angelicae Sinensis Radix (Danggui), Ligustici Chuanxiong Rhizoma (Chuanxiong), adding a little wine. For retroverted scabs after eruption due to external evil qi injury, use Ginseng Radix et Rhizoma (Renshen), Paeoniae Radix (Shaoyao), Forsythiae Fructus (Lianqiao), Scutellariae Caulis (Huangqin Shao), Glycyrrhizae Radix et Rhizoma caulis (Gancao Shao), Angelicae Dahuricae Radix (Baizhi), wine-fried Angelicae Sinensis Radix (Jiu Danggui), Ligustici Chuanxiong Rhizoma (Chuanxiong), and a little Aucklandiae Radix (Muxiang). In all smallpox cases, distinguish the patient's clear/turbid constitution and assess courage/fear based on physique and Qi. For two types of black depression due to Qi insufficiency preventing full emergence, use wine-fried Astragali Radix (Jiu Huangqi), Ginseng Radix et Rhizoma (Renshen), and wine-fried Lithospermi Radix (Jiu Zicao). If color is normal but pale despite following the above method to mature, or if color is abnormal, use Ligustici Chuanxiong Rhizoma (Chuanxiong), Angelicae Sinensis Radix (Danggui), Paeoniae Radix (Shaoyao), and Safflower wine. If purple upon maturation indicating heat, use Cimicifugae Rhizoma (Shengma), Puerariae Radix (Gegen), Scutellariae Radix (Huangqin), Coptidis Rhizoma (Huanglian), Cinnamomi Cortex (Gui), and Forsythiae Fructus (Lianqiao). For severe cases, use Rhinocerotis Cornu (Xijiao) slices to strongly resolve toxins. Ash-gray white color in quiet/timid patients indicates cold; neat/courageous/restless/feverish patients indicate heat. Full white color resembling bean shells during scabbing is due to excessive water intake initially, causing uneven scabbing, commonly called "retroverted scab"; this is harmless, merely requiring exterior-consolidating agents. Monitor urination and defecation: if constipated, unblock bowels; if urinary retention, unblock urine. For initial restlessness, delirium, mania, and extreme thirst, drinking water leads to uneven scabbing; urgently resolve the branch with cooling herbs like Yi Yuan San (Benefit Prime Powder). For itching and collapsing, differentiate deficiency/excess via appearance, color, and pulse. Excess: strong pulse, robust Qi. Deficiency: weak pulse, timid Qi. For deficiency itch, use exterior-consolidating agents plus blood-cooling herbs. For excess itch or constipation, give small amounts of Rhei Radix et Rhizoma (Dahuang) and other cold herbs to purge accumulated stool. For mild Qi timidity, apply talcum powder mixed with light honey water to sores with a feather. Sparse rashes are non-toxic; dense rashes are toxic; resolve with cooling herbs, even over ten doses, without harming eyes later. Dryness requires fire-retarding methods; dampness requires damp-draining methods. Fire-retarding uses mild agents like Schizonepetae Spica (Jingjie), Cimicifugae Rhizoma (Shengma), Glycyrrhizae Radix et Rhizoma (Gancao), and Puerariae Radix (Gegen). Damp-draining addresses surface dampness using wind-dispersing herbs like Angelicae Dahuricae Radix (Baizhi) and Saposhnikoviae Radix (Fangfeng). For smallpox eye injury, use Gardeniae Fructus (Shanzhi), Cassiae Semen (Juemingzi), Paeoniae Radix Rubra (Chishao), Angelicae Sinensis Radix radix (Danggui Xu), Scutellariae Radix (Huangqin), Coptidis Rhizoma (Huanglian), Saposhnikoviae Radix (Fangfeng), Forsythiae Fructus (Lianqiao), Cimicifugae Rhizoma (Shengma), and Platycodonis Radix (Jiegeng), ground to powder, taken in small doses. If vision is impaired, clarity returns after 100 days as Qi and Blood recover. Carbuncles are mostly caused by exterior excess and Blood heat; treat upper and lower separately, urgency is critical. For suppuration, prioritize cooling herbs: Paeoniae Radix Rubra (Chishao), Glycyrrhizae Radix et Rhizoma nodulus (Gancao Jie), Forsythiae Fructus (Lianqiao), Platycodonis Radix (Jiegeng); ascend with Cimicifugae Rhizoma (Shengma) and Puerariae Radix (Gegen); descend with Arecae Semen (Binglang) and Achyranthis Bidentatae Radix (Niuxi); assist with Fritillariae Bulbus (Beimu), Lonicerae Japonicae Caulis (Rendongcao), Angelicae Dahuricae Radix (Baizhi), and Trichosanthis Fructus (Gualou). Use Rhei Radix et Rhizoma (Dahuang) for dry stools; Scutellariae Radix (Huangqin) and Phellodendri Cortex (Huangbai) for fever. Black smallpox belongs to Blood heat, primarily cool blood; white belongs to Qi deficiency, primarily tonify Qi. Central black depression with peripheral white and late emergence requires combined treatment. Initial spontaneous sweating is acceptable due to damp-heat steaming. Smallpox is divided into Qi/Blood and Deficiency/Excess, monitored daily, often involving Qi/Blood insufficiency. For deficiency, use Astragali Radix (Huangqi) and blood-generating/moving agents, slightly assisted by wind-dispersing herbs. For excess, use Paeoniae Radix Alba (Baishao) and Scutellariae Radix (Huangqin) as sovereigns, Angelicae Dahuricae Radix (Baizhi) and Forsythiae Fructus (Lianqiao) as ministers. For cold patterns, Chen's formulas are applicable. Shen Su Yin (Ginseng and Perilla Decoction) is appropriate whether erupted or not. The regulatory method generally involves activating blood, regulating Qi, calming the exterior, harmonizing the middle, lightly clearing toxicity, combining warm and cool agents. Warm agents include Angelicae Sinensis Radix (Danggui), Astragali Radix (Huangqi), Aucklandiae Radix (Muxiang); cool agents include Peucedani Radix (Qianhu), Glycyrrhizae Radix et Rhizoma (Gancao), Puerariae Radix (Gegen), Cimicifugae Rhizoma (Shengma). Assist with Ligustici Chuanxiong Rhizoma (Chuanxiong), Paeoniae Radix (Shaoyao), Aurantii Fructus Immaturus (Zhike), Platycodonis Radix (Jiegeng), Akebiae Caulis (Mutong), Lithospermi Radix (Zicao), Glycyrrhizae Radix et Rhizoma (Gancao). Initial spontaneous sweating is acceptable due to damp-heat steaming. Topical paste for carbuncles: Fritillariae Bulbus (Beimu), Arisaematis Rhizoma (Nanxing), Bombyx Batryticatus (Jiangcan), Trichosanthis Radix (Tianhuafen), Angelicae Dahuricae Radix (Baizhi), Aconiti Lateralis Radix Praeparata (Caowu), Rhei Radix et Rhizoma (Dahuang), Gleditsiae Sinensis Fructus (Zhuyazaojiao) in equal parts, Halloysitum Rubrum (Han Shui Shi) doubled. Grind to powder, mix with vinegar for application. A man in his twenties suffered from smallpox; after scab shedding, he suddenly developed lockjaw, rigid limbs unable to flex/extend, periumbilical pain with profuse cold sweat during attacks, stopping when pain ceased, intermittent episodes. Pulse was wiry, tight, and rapid, like a straight string. He was extremely laborious, likely injuring blood through fatigue, contracting wind-cold in mountainous areas, further depleting blood during eruption. Treatment required warming herbs to nourish blood and acrid-cool herbs to disperse wind. Sovereign: Angelicae Sinensis Radix (Danggui Shen), Paeoniae Radix Alba (Baishao). Ministers: Ligustici Chuanxiong Rhizoma (Chuanxiong), Citri Reticulatae Pericarpium (Qingpi), Uncariae Ramulus cum Uncis (Gouteng). Assists: Atractylodis Macrocephalae Rhizoma (Baizhu), Citri Reticulatae Pericarpium (Chenpi). Guide: Glycyrrhizae Radix et Rhizoma (Gancao), Cinnamomi Cortex (Guipi), Aquilariae Resina (Nanmuxiang), Scutellariae Radix (Huangqin), plus little Safflower (Honghua). Decocted and administered, resulting in cure. My nephew, aged six or seven, had smallpox with fever, slight thirst, and diarrhea. The physician prescribed Muxiang San (Aucklandia Powder) with ten cloves (Dingxiang). I observed delayed eruption, partly due to Qi weakness from diarrhea, but the foul, stagnant stool indicated heat steaming downward, not cold. I urgently stopped the previous prescription (already one dose given) and prescribed Huanglian Jiedu Tang (Coptis Decoction for Resolving Toxin) plus Atractylodis Macrocephalae Rhizoma (Baizhu) for nearly ten doses to resolve heat. Diarrhea stopped, and pustules emerged. His skin remained slightly hot with swollen hands/feet; treated with cooling-tonifying herbs, recovered in one month. A seventeen-year-old had smallpox with fever and severe drowsiness, pulse large and seemingly rapid. Prescribed Ginseng Radix et Rhizoma (Renshen), Atractylodis Macrocephalae Rhizoma (Baizhu), Astragali Radix (Huangqi), Angelicae Sinensis Radix (Danggui), Citri Reticulatae Pericarpium (Chenpi) in large, concentrated decoction. After twenty doses, pustules emerged; after another twenty, pustules formed, leaving no intact skin. Someone suggested Chen's original formula; I said as long as there is no deficiency-cold, continue the previous formula. Recovered after sixty doses.