春温夏热秋清凉，冬气冷冽令之常，伤之四时皆正病，非时有气疫为殃。应冷反温
冬温病，应温反冷寒疫伤，瘟疫长幼相传染，须识岁气汗攻良。
【注】冬病伤寒，春病伤风，夏病暑病，秋病疟疾，皆四时正令之常病也。若春应暖
而反寒，夏应热而反凉，秋应凉而反热，冬应寒而反温，此非其时而有其气，疫为殃也。
冬应冷反温而病伤寒者，名曰冬温。春应温反寒而病伤寒者，名曰寒疫。若一时之气不
正，长幼皆病，互相传染，名曰瘟疫。凡治此病，须识岁气太过不及，六淫胜复，人之
强弱，脏之寒热，量其轻重，或汗或攻。轻以刘完素之双解散，重以李杲之二圣救苦丸，
随证施治可也。
冬伤于寒春病温，夏日热病早亏阴，脉浮头疼发热渴，不恶寒兮是所因。无汗河间
两解法，有汗清下早当寻，失治昏狂诸热至，无证随经以意神。
【注】经曰∶冬伤于寒，春必病温，至夏为热病。热病者，皆伤寒之类也。冬伤于寒，
谓冬伤正令微寒未即病也。早亏阴，谓冬不藏精之人，或辛苦之人，汗出内外失其固密，
在冬则早已损伤肾藏阴气，阳热独治，所以至春一感微邪，即引内热，炎炎之势，不能
已矣。故病而即渴不恶寒也。初病无汗有表证者，从刘完素两解汤治法可也。有汗内热
盛者，或清或攻，急泻其阳而救其阴，若因循失治，昏狂诸热证至，则缓不及事也。无
证，谓表里无证，当随六经以意消息治之，自可通神也。
春季温暖、夏季炎热、秋季凉爽、冬季寒冷，这是四季气候变化的正常规律。如果受到这些正常气候的邪气侵袭，属于四时正病；如果不是正常的时令气候，而是反常的气候（疫气）作祟，就会造成灾殃。
应当寒冷却反而温暖，导致冬温病；应当温暖却反而寒冷，导致寒疫病；瘟疫则长幼之间相互传染，必须识别当年的岁气（运气），采用发汗或攻下的方法治疗才良好。
【注】冬季患病多为伤寒，春季患病多为伤风，夏季患病多为暑病，秋季患病多为疟疾，这些都是四时正常气候下的常见病。如果春天应该暖和却反而寒冷，夏天应该炎热却反而凉爽，秋天应该凉爽却反而炎热，冬天应该寒冷却反而温暖，这就是非其时而有其气，是疫气造成的灾殃。冬天应当寒冷却反而温暖而患伤寒病的，名叫冬温。春天应当温暖却反而寒冷而患伤寒病的，名叫寒疫。如果一时的气候不正，老人和小孩都生病，互相传染，名叫瘟疫。凡是治疗这些疾病，必须识别岁气的太过与不及，六淫（风、寒、暑、湿、燥、火）的胜复关系，人的体质的强弱，脏腑的寒热状况，衡量病情的轻重，或者用发汗法，或者用攻下法。病情轻的用刘完素的“双解散”，病情重的用李杲的“二圣救苦丸”，随证施治即可。
冬季感受寒邪，到了春天发生温病；夏季发生的热病，往往是因为早期阴精亏损。症状表现为脉浮、头痛、发热、口渴，且不恶寒，这就是病因所在。如果没有汗，可用刘完素的“两解法”（双解散）；如果有汗且内热盛，应当尽早寻求清热或攻下的方法。如果失治，会导致昏迷、狂乱等各种热证出现；如果没有明显的表里证候，应当根据六经辨证，凭意消息（灵活斟酌）治疗，自然能达到神妙的境界。
【注】经典说：冬季感受寒邪，春天必定发生温病，到了夏天就变成热病。热病，都属于伤寒的类别。所谓“冬季感受寒邪”，是指冬季感受了正常气候中轻微的寒邪，并没有立即发病。所谓“早亏阴”，是指冬天不能藏精的人，或者是辛苦劳作的人，出汗导致内外固密失职，在冬季就已经损伤了肾脏的阴气，阳气独盛，所以到了春天一旦感受微邪，就会引动内热，火势炎炎，无法停止。因此发病时就口渴且不恶寒。初起无汗且有表证的，可以按照刘完素的“两解汤”治法治疗。有汗且内热盛的，或者用清法，或者用攻法，急泻阳热以救阴液，如果因循拖延失治，昏迷狂乱等各种热证到来，就来不及救治了。“无证”，是指没有明显的表里证候，应当随着六经的变化，凭意斟酌治疗，自然可以通神。
Spring is warm, summer is hot, autumn is cool, and winter is cold; this is the normal order of seasonal climate changes. Injury by these normal seasonal climates constitutes a regular disease of the four seasons; however, if injured by abnormal climatic factors (epidemic qi) contrary to the season, disaster ensues.
When it should be cold but turns warm, Winter-Warmth Disease occurs; when it should be warm but turns cold, Cold-Epidemic injury occurs. Epidemics spread among people of all ages through transmission. One must recognize the annual climate (Yunqi) and employ sweating or purging methods for effective treatment.
[Note] Diseases in winter are typically Cold Damage (Shanghan); in spring, Wind Injury (Shangfeng); in summer, Summerheat Disease (Shu Bing); in autumn, Malaria (Nue Ji). These are common diseases corresponding to the normal climate of the four seasons. If spring should be warm but turns cold, summer should be hot but turns cool, autumn should be cool but turns hot, and winter should be cold but turns warm, this represents "having the qi of one season at the wrong time," causing epidemic disasters. When winter should be cold but turns warm, leading to Cold Damage disease, it is named Winter-Warmth (Dong Wen). When spring should be warm but turns cold, leading to Cold Damage disease, it is named Cold-Epidemic (Han Yi). If the climate of a specific period is irregular, affecting both the elderly and the young who infect each other, it is named Plague/Epidemic (Wen Yi). In treating such diseases, one must discern whether the annual climate is excessive or deficient, the overcoming and recovery of the Six Excesses (Liu Yin), the strength or weakness of the person, and the cold or heat of the zang-fu organs. Assessing the severity, one may use either sweating or purging methods. For mild cases, Liu Wansu's Shuangjie San (Double-Resolution Powder) is used; for severe cases, Li Gao's Ersheng Jiuku Wan (Two-Saints Rescue-Bitterness Pill) is employed. Treatment should follow the syndrome differentiation.
Injury by Cold in winter leads to Warmth Disease in spring; Heat Disease in summer often stems from early deficiency of Yin. Symptoms include floating pulse, headache, fever, thirst, and absence of aversion to cold; this is the etiology. If there is no sweat, Liu Wansu's Two-Resolution method (Shuangjie Tang) applies; if there is sweat and intense internal heat, clearing or purging methods should be sought early. Failure to treat promptly leads to coma, mania, and various heat syndromes. If there are no obvious exterior or interior signs, treatment should be adjusted according to the Six Meridians with flexible judgment, achieving divine efficacy.
[Note] The Classics state: "Injury by Cold in winter leads to Warmth Disease in spring, which becomes Heat Disease in summer." Heat Disease belongs to the category of Cold Damage. "Injury by Cold in winter" refers to contracting slight normal Cold in winter without immediate onset of disease. "Early deficiency of Yin" refers to individuals who fail to store essence during winter, or those engaged in hard labor whose sweating disrupts internal and external consolidation. This damages Kidney Yin in winter, leaving Yang heat unopposed. Thus, upon encountering slight pathogenic factors in spring, internal heat is triggered, burning fiercely and uncontrollably. Hence, thirst and absence of aversion to cold occur immediately upon onset. For initial cases with no sweat and exterior signs, Liu Wansu's Shuangjie Tang method is applicable. For cases with sweat and intense internal heat, either clearing or purging methods should be used urgently to drain Yang heat and rescue Yin. Delayed treatment allows coma, mania, and other heat syndromes to arise, making rescue impossible. "No signs" refers to the absence of obvious exterior or interior syndromes; treatment should be modulated according to the progression through the Six Meridians, achieving spiritual mastery.