脉
阳濡弱，阴弦紧，更遇温气，变为温疫。左手脉大于右手，浮缓而盛，按之无力。
证
众人病一般者，乃天行时疫也。悉由气运郁发，迁正退位之所致也。
治
冬应寒而反温，春发温疫，败毒散主之；春应温而反凉，夏发燥疫，大柴胡汤主之；夏应热而反寒，秋
发寒疫，五积散主之；秋应凉而反淫雨，冬发湿疫，五苓散主之。凡温疫，切不可作伤寒症
治，而大汗大下也。但当从乎中治，而用少阳、阳明二经药，少阳小柴胡汤，阳明升麻葛根汤。
看所中阴阳，而以二方加减和治之，殊为切当。人参败毒散，
治四时温疫。通用羌活冲和汤，治温疫初感，一、二日间服之取汗，其效甚速。
方
凡入温疫之家，以麻油涂鼻孔中，则不传染。出以纸捻探鼻深入，令嚏之为佳。
一方以雄黄、苍术为细末，香油调敷鼻内。或用雄黄末，水调鼻内。虽与病患同卧，亦不相染。
宣圣辟瘟丹 腊月二十四日井花水，在平旦第一汲者是也。盛净器中，量人口多少，浸乳香至岁
朝五更时，暖令温。自幼至长，每人以乳香一小块，饮水一、二呷咽下，则一年不患时疫。
神圣辟瘟丹（诀云∶圣神辟瘟丹，留传在世间，正元焚一灶，疫疠自祛蠲）〔批〕
（按上方皆预防瘟疫之剂）
苍术（为君，倍用） 羌活 独活 白芷 香附 大黄 甘松 三奈 赤箭 雄黄（各等分）
上为末，面糊为丸，如弹子大，黄丹为衣，晒干，正月初一平旦时焚一炷，辟除一岁瘟疫邪气。
人参败毒散 治四时不正之气，冬应寒而反热，夏应热而反寒，春应温而反凉，秋应凉而反温，非其
时而有其气，故病者大小无异。大抵使人痰涎壅盛，壮热如火，头疼身痛，项强睛疼，声哑
腮肿，俗呼浪子瘟，或称虾蟆瘟。城市乡村，家户相类，悉根据本方加干葛。若寒热往来，必用小柴胡汤。（二
方俱见伤寒条下）
加味柴胡汤 治挟岚瘴溪源蒸毒之气，其状血乘上焦，病欲来
时，令人迷困，甚则发躁狂妄，亦有哑而不能言者，皆由瘀血攻心，毒涎聚胃。
柴胡 黄芩 半夏 人参 枳壳 大黄 甘草
上锉一剂，姜枣煎，空心服。哑瘴，食后服。
大力子汤 治大头天行病，腮颊颈项肿胀，头疼发热，证似伤寒。兼治哑瘴。
黄芩（酒洗，二钱） 黄连（酒炒，二钱） 桔梗（一钱五分） 甘草（一钱） 连翘（一
钱） 鼠粘子（炒研） 玄参（各一钱） 大黄（酒蒸，一钱五分） 荆芥（三分） 防风（三分）
羌活（三分） 石膏（一钱五分）
上锉一剂，生姜煎服。
治四时瘟疫，头痛发热，众人一般病者。（孙钝庵传） 黑砂糖一
盏，入姜汁二盏，化开，令病患服之。当时憎寒壮热，汗出立愈。
二圣救苦丸（万左川传） 治伤寒瘟疫。
大黄（四两，酒蒸） 牙皂（二两）
上末，面糊丸如绿豆大，每服四十丸，绿豆汤送下，大汗为效。
脉象
阳气表现为濡弱，阴气表现为弦紧，若再遇到温热之气，就会演变为温疫。左手脉象比右手大，呈现浮缓且盛大之象，但重按则感觉无力。
证候
如果众人患的病症状相同，这就是天行时疫（流行性传染病）。这完全是由气候运气郁结而发，以及正常节气交替（迁正退位）失常所导致的。
治法
冬季应当寒冷却反而温暖，春季引发温疫，用人参败毒散为主治疗；春季应当温暖却反而凉爽，夏季引发燥疫，用大柴胡汤为主治疗；夏季应当炎热却反而寒冷，秋季引发寒疫，用五积散为主治疗；秋季应当凉爽却反而多雨，冬季引发湿疫，用五苓散为主治疗。凡是温疫，切不可当作伤寒症来治疗，从而使用大汗或大下之法。只应当从“中”论治，使用少阳经和阳明经的药物，如少阳经的小柴胡汤，阳明经的升麻葛根汤。根据患者受邪的阴阳属性，对这两个方剂进行加减调和治疗，非常恰当。人参败毒散，用于治疗四季的温疫。通用羌活冲和汤，用于治疗温疫初感，在一、二日内服用以取汗，效果非常迅速。
方剂
凡是进入温疫患者的家中，用麻油涂抹鼻孔，就不会被传染。出来时用纸捻探入鼻腔深处，引起打喷嚏为佳。
另一个方子是用雄黄、苍术研成细末，用香油调匀敷在鼻内。或者只用雄黄末，用水调匀滴入鼻内。即使与病患同床共卧，也不会被感染。
宣圣辟瘟丹：采集腊月二十四日清晨第一次汲取的井花水（清晨第一桶井水），盛放在干净的容器中，根据人口多少，浸泡乳香直到正月初一黎明时分，加热至温热。从幼童到成人，每人含一小块乳香，饮水一两口咽下，则一年不会患上时疫。
神圣辟瘟丹（歌诀说：圣神辟瘟丹，流传在世间，正月初一焚一灶，瘟疫自然消除）〔批注〕（以上方剂都是预防瘟疫的制剂）
苍术（作为君药，加倍使用） 羌活 独活 白芷 香附 大黄 甘松 三奈 赤箭 雄黄（各等分）
以上药材研为细末，用面糊制成丸药，大小如弹子，用黄丹做外衣，晒干，在正月初一清晨焚烧一炷香的时间，以辟除一年的瘟疫邪气。
人参败毒散：治疗四时不正之气，冬季应当寒冷却反而热，夏季应当热却反而寒，春季应当温暖却反而凉，秋季应当凉爽却反而温，非其时而出现其气，所以患病的人无论老少症状都差不多。大体上使人痰涎壅盛，高热如火，头痛身痛，颈项强直眼睛疼痛，声音嘶哑腮部肿胀，俗称浪子瘟，也称为虾蟆瘟。城市和乡村，家家户户情况相似，都依据本方加入干葛（葛根）。如果出现寒热往来，必须用小柴胡汤。（两个方剂均见《伤寒论》相关条目下）
加味柴胡汤：治疗夹杂岚瘴溪源蒸腾毒气的病症，其症状是血邪上乘上焦，病欲发作时，令人迷乱困倦，严重时烦躁狂妄，也有哑巴不能说话的，这都是由于瘀血攻心，毒涎聚集在胃所致。
柴胡 黄芩 半夏 人参 枳壳 大黄 甘草
以上药材切碎为一剂，加生姜、大枣煎煮，空腹服用。如果是哑瘴，则在饭后服用。
大力子汤：治疗大头天行病（大头瘟），腮颊颈项肿胀，头痛发热，症状类似伤寒。兼治哑瘴。
黄芩（酒洗，二钱） 黄连（酒炒，二钱） 桔梗（一钱五分） 甘草（一钱） 连翘（一钱） 鼠粘子（牛蒡子，炒后研碎） 玄参（各一钱） 大黄（酒蒸，一钱五分） 荆芥（三分） 防风（三分） 羌活（三分） 石膏（一钱五分）
以上药材切碎为一剂，加生姜煎服。
治疗四季瘟疫，头痛发热，众人症状相同的病症。（孙钝庵传授）黑砂糖一盏，加入姜汁二盏，化开，让患者服用。当时恶寒壮热，出汗后立即痊愈。
二圣救苦丸（万左川传授）：治疗伤寒瘟疫。
大黄（四两，酒蒸） 牙皂（二两）
以上研为细末，用面糊制成如绿豆大小的丸药，每次服用四十丸，用绿豆汤送下，以出大汗为见效。
Pulse
Yang presents as soggy and weak (Ru Ruo), Yin presents as string-taut and tight (Xian Jin). If further exposed to warm qi, it transforms into Warm Epidemic (Wen Yi). The left hand pulse is larger than the right, floating, slow, and vigorous, but feels powerless upon deep pressure.
Symptoms
When the majority of people suffer from similar illnesses, this is Heavenly Movement Seasonal Epidemic (Tian Xing Shi Yi), a contagious disease spreading through the air. It is entirely caused by the stagnation and eruption of climatic fortune, resulting from the improper transition of seasonal positions (Qian Zheng Tui Wei).
Treatment
If winter should be cold but turns warm, causing Warm Epidemic in spring, Ren Shen Bai Du San (Ginseng Decoction for Overcoming Toxins) is the primary formula. If spring should be warm but turns cool, causing Dry Epidemic in summer, Da Chai Hu Tang (Major Bupleurum Decoction) is the primary formula. If summer should be hot but turns cold, causing Cold Epidemic in autumn, Wu Ji San (Five Accumulations Powder) is the primary formula. If autumn should be cool but turns rainy, causing Damp Epidemic in winter, Wu Ling San (Five-Ling Powder) is the primary formula. In all cases of Warm Epidemic, one must absolutely not treat it as Tai Yang Disease (Shang Han) and induce severe sweating or purgation. Instead, treatment should follow the "Middle" principle, using herbs from the Shaoyang (Lesser Yang) and Yangming (Bright Yang) meridians, such as Xiao Chai Hu Tang (Minor Bupleurum Decoction) for Shaoyang and Sheng Ma Ge Gen Tang (Kudzu Root and Cimicifuga Decoction) for Yangming. Based on whether the pathogen affects Yin or Yang, modify and harmonize these two formulas; this is highly appropriate. Ren Shen Bai Du San treats seasonal Warm Epidemics. Qiang Huo Chong He Tang is generally used for initial contraction of Warm Epidemic; taking it within one or two days to induce sweating yields very rapid results.
Formulas
Whenever entering the home of a patient with Warm Epidemic, applying sesame oil inside the nostrils prevents infection. Upon leaving, inserting a rolled paper wick deep into the nasal cavity to induce sneezing is beneficial.
Another method involves grinding Xiong Huang (Realgar) and Cang Zhu (Atractylodes Rhizome) into fine powder, mixing with sesame oil, and applying inside the nose. Alternatively, use only Xiong Huang powder mixed with water applied to the nose. Even sleeping in the same bed as the patient will not result in transmission.
Xuan Sheng Bi Wen Dan (Prophet's Plague-Repelling Pill): Collect well-water drawn at dawn on the 24th day of the twelfth lunar month (the first bucket of water). Store in a clean vessel. Soak Ru Xiang (Frankincense) according to the number of people until the early morning of the first day of the new year. Warm it slightly. From children to adults, each person swallows a small piece of Frankincense with one or two sips of water, ensuring they will not contract seasonal epidemics for a year.
Shen Sheng Bi Wen Dan (Divine Plague-Repelling Pill) [Note: These above formulas are all preventive agents against plague]
Cang Zhu (as Sovereign herb, doubled in dosage), Qiang Huo (Notopterygium Rhizome), Du Huo (Angelicae Pubescentis Radix), Bai Zhi (Angelicae Dahuricae Radix), Xiang Fu (Cyperus Rhizome), Da Huang (Rhei Radix et Rhizoma), Gan Song (Nardostachys Radix et Rhizoma), San Nai (Kaempferiae Rhizoma), Chi Jian (Achyranthes Root), Xiong Huang (Realgar) (all in equal parts).
Grind into powder, bind with wheat paste into pills the size of a bullet, coat with Huang Dan (Lead Monoxide), dry in the sun. On the first day of the first lunar month at dawn, burn one incense stick's worth to repel epidemic pathogens for the year.
Ren Shen Bai Du San: Treats irregular Qi of the four seasons. Winter should be cold but is hot; summer should be hot but is cold; spring should be warm but is cool; autumn should be cool but is warm. When non-seasonal Qi appears, patients of all ages present similarly. Generally, it causes phlegm-saliva congestion, high fever like fire, headache and body pain, stiff neck and painful eyes, hoarseness, and swollen cheeks. Commonly called Lang Zi Wen (Prodigal Son Plague) or Xia Ma Wen (Toad Plague). In cities and villages, households are affected similarly; all should base treatment on this formula adding Gan Ge (Kudzu Root). If there is alternating chills and fever, Xiao Chai Hu Tang must be used. (Both formulas are found under the Shang Han section.)
Jia Wei Chai Hu Tang: Treats conditions complicated by miasma and toxic vapors from mountain streams and valleys. The pathology involves blood attacking the Upper Jiao. Before the illness manifests, it causes confusion and lethargy; severely, it leads to restlessness and madness, or even mutism. This is due to blood stasis attacking the Heart and toxic saliva accumulating in the Stomach.
Chai Hu (Bupleuri Radix), Huang Qin (Scutellariae Radix), Ban Xia (Pinelliae Rhizoma), Ren Shen (Ginseng Radix), Zhi Ke (Aurantii Fructus), Da Huang (Rhei Radix et Rhizoma), Gan Cao (Glycyrrhizae Radix et Rhizoma).
Cut one dose, decoct with Sheng Jiang (Zingiberis Rhizoma) and Da Zao (Jujubae Fructus), take on an empty stomach. For Ya Zhang (Mutism Miasma), take after meals.
Da Li Zi Tang: Treats Da Tou Tian Xing Bing (Great Head Epidemic), characterized by swelling of the cheeks, jaw, and neck, headache, and fever, resembling Shang Han. Also treats Ya Zhang.
Huang Qin (Scutellariae Radix, wine-washed, 2 qian), Huang Lian (Coptidis Rhizoma, wine-fried, 2 qian), Jie Geng (Platycodonis Radix, 1.5 qian), Gan Cao (Glycyrrhizae Radix et Rhizoma, 1 qian), Lian Qiao (Forsythiae Fructus, 1 qian), Niu Bang Zi (Arctii Fructus, fried and ground), Xuan Shen (Scrophulariae Radix, 1 qian), Da Huang (Rhei Radix et Rhizoma, wine-steamed, 1.5 qian), Jing Jie (Schizonepetae Herba, 3 fen), Fang Feng (Saposhnikoviae Radix, 3 fen), Qiang Huo (Notopterygii Rhizoma et Radix, 3 fen), Shi Gao (Gypsum Fibrosum, 1.5 qian).
Cut one dose, decoct with Sheng Jiang, and take orally.
Treats seasonal plagues with headache, fever, and uniform symptoms among the populace. (Transmitted by Sun Dun'an) One cup of black sugar, mixed with two cups of ginger juice, dissolved and given to the patient. Immediate relief occurs with sweating after consuming this for chills and high fever.
Er Sheng Jiu Ku Wan (Two Sages' Life-Saving Pills) (Transmitted by Wan Zuochuan): Treats Shang Han and plagues.
Da Huang (Rhei Radix et Rhizoma, 4 liang, wine-steamed), Ya Zao (Gleditsiae Sinensis Fructus, 2 liang).
Grind into powder, bind with wheat paste into pills the size of mung beans. Take 40 pills per dose, washed down with mung bean soup. Effect is achieved when profuse sweating occurs.