王海藏曰∶大头病者，虽在半身以上。热伏于经，以感天地四时非节瘟疫之气，所着以成此疾。
至于溃裂脓出，而又染他人，所谓疫疠也。大抵足阳明邪热太甚，实资少阳相火为之炽，多在少阳
，或在阳明，甚则逆传。视其肿势在何部分，随
其经而取之。湿热为肿，火盛为痛，此邪发于首，多在两耳前后所见。先出者为主为根，治之宜早。药
不宜速，恐过其病所，谓上热未除，中寒已作，有伤人命矣，此疾自外而之内者，是谓血病。况头部受邪，
见于无形之处，至高之分，当先缓而后急。
先缓者，谓邪气在上，着无形之部分。既着无形，所传无定，若有重剂大泻之，则其邪不去，反
过其病矣。虽用缓药，若又急服之，或食前，或顿服，咸失缓体，则药不能除疾矣。当徐徐服，渍无形之
邪。或药性味形体，据象服饵，皆须不离缓体。及寒药，或酒炒浸之类，皆是也。
后急者，谓前缓剂已经高分泻，邪气入于中，是到阴部，染于有形质之所，若不速去，反损阴也。此却
为客邪，当即去之，是治客以急也。
且治主当缓者，谓阳邪在上，阴邪在下，各属本家病也，若急去之，不惟不能解其纷，而反致其乱矣，
所以治主当缓也。治客当急者，谓阳分受阳邪，阴分受阴邪，主也；阴分受阳邪，阳分受阴邪，客也。凡
所谓客，当急去之，此治客以急也。
假令少阳、阳明之为病，少阳为邪者，出于耳前后也；阳明者，首面大肿也，先以黄芩、黄连、甘草通
炒过，煎，不
住呷之。或服毕再用大黄，或酒浸，或煨，又以牛蒡子炒香煎，纳芒硝，各等分，亦细细呷之，当食
后用，徐微得利。及邪气已，只服前药。不已服后药，根据前项次第用之，取大便利，邪已即止。如阳明渴
者加栝蒌根，阳明行经加升麻、葛根、芍药之类，太阳行经加羌活、防风、荆芥之类，选而加之，并与上药
均分，不可独用散也。
王海藏说：大头病，虽然病变部位在半身以上，但这是因为热邪潜伏在经脉中，又感受了天地四时不合节令的瘟疫之气，从而染上而形成的疾病。
到了溃烂裂开、流出脓液，并且传染给他人，这就是所谓的疫疠（具有强烈传染性的疫病）。大抵是因为足阳明经的邪热过于严重，实际上借助了少阳相火的助长而变得炽盛，病位多在少阳经，或者在阳明经，严重时则会逆向传变。观察肿胀的部位在哪个部分，就顺着该经络进行治疗。湿热导致肿胀，火邪炽盛导致疼痛，这种邪气发于头部，多出现在两耳前后的区域。先出现的症状为主症、为病根，治疗应当尽早进行。
用药不宜过猛过快，恐怕药力超过了病所，造成“上部的热邪尚未清除，中焦的寒邪已经产生”的局面，这会伤害人的性命。这种疾病是从外部侵入内部的，属于血分病变。况且头部受邪，发生在无形的高位，治疗应当先缓后急。
所谓“先缓”，是指邪气在上部，附着于无形的部位。既然附着于无形之处，其传变就没有定规，如果使用重剂猛烈攻下，邪气不仅不能去除，反而会使病情加重。即使使用缓和的药物，如果又急于服用，无论是饭前服还是顿服，都失去了“缓”的本意，那么药物就不能祛除疾病了。应当慢慢服用，以浸渍消散无形的邪气。无论是药物的性味形态，还是依据象数理论来服用，都必须不离“缓”的原则。比如用寒凉药，或者用酒炒、酒浸等方法，都是这样的道理。
所谓“后急”，是指前面的缓剂已经将高位的热邪泻去，邪气进入中部，到达阴部，沾染在有形质的脏腑组织里，如果不迅速去除，反而会损伤阴气。这时邪气变成了客邪，应当立即去除，这就是“治客以急”。
而且治疗主症应当用缓法，是指阳邪在上，阴邪在下，各自属于本经的病证，如果急于去除，不但不能解开纷乱，反而会导致混乱，所以治疗主症应当用缓法。治疗客邪应当用急法，是指阳分受阳邪，阴分受阴邪，这是主症；阴分受阳邪，阳分受阴邪，这是客邪。凡是称为客邪的，应当迅速去除，这就是“治客以急”。
举例来说，少阳经和阳明经的疾病，少阳经受邪，表现为耳朵前后肿痛；阳明经受邪，表现为头面部大面积肿胀。先用黄芩、黄连、甘草，全部通炒过后煎煮，不停地小口啜饮。或者服完上述药物后，再用大黄，或者用酒浸，或者煨制，再加上牛蒡子炒香煎煮，加入芒硝，各等分，也细细地啜饮，应当在饭后服用，使大便微微通畅。等到邪气已去，只服用前面的药物。如果病未愈，则服用后面的药物，按照前面的次第使用，以求大便通畅，邪气去除即停药。如果阳明经出现口渴，加瓜蒌根；如果邪气在阳明经运行，加升麻、葛根、芍药之类；如果邪气在太阳经运行，加羌活、防风、荆芥之类，选择加入，并与上面的药物均分，不可单独使用散剂。
Wang Haicang stated: The disease of the "Big Head" (Da Tou Wen), although manifesting in the upper half of the body, arises because heat is latent within the meridians and one contracts epidemic qi that is out of season from heaven and earth. This leads to the formation of this illness.
When it progresses to ulceration, cracking, pus discharge, and transmission to others, it is referred to as Yi Li (epidemic pestilence). Generally, the pathogenic heat of the Foot-Yangming Meridian is excessive, which actually fuels the ministerial fire of the Shaoyang, causing it to blaze. The pathology mostly resides in the Shaoyang or Yangming meridians; in severe cases, it transmits reversely. One should observe which part of the body exhibits swelling and treat according to the affected meridian. Damp-heat causes swelling, while excessive fire causes pain. Since this pathogen originates in the head, it is mostly seen around the front and back of both ears. The symptoms that appear first are the primary manifestation and the root of the disease; treatment should be initiated early.
Medication should not be administered too rapidly or aggressively, lest the medicinal force overshoot the site of the disease. This could result in a situation where "the heat above has not been cleared, but cold in the middle has already arisen," thereby endangering life. This disease enters from the exterior into the interior and is classified as a blood-level disorder. Furthermore, since the head receives the pathogen at a high and formless location, treatment should proceed with a slow approach first, followed by an urgent one.
The "slow approach" refers to the fact that the pathogen is located superiorly, adhering to formless regions. Once adhering to the formless, its transmission is unpredictable. If heavy purgatives are used for drastic evacuation, the pathogen will not be expelled, but rather the condition will worsen. Even when using mild medications, if they are taken hastily—whether before meals or in a single dose—the essence of "slowness" is lost, and the medication will fail to eradicate the disease. It should be taken slowly to macerate and dissipate the formless pathogen. Whether considering the nature, flavor, and form of the drugs, or administering them based on symbolic correspondences, the principle must remain consistent with "slowness." For instance, using cold-natured herbs, or processing them with wine frying or wine soaking, all adhere to this principle.
The "urgent approach" refers to the stage after the previous mild agents have drained the heat from the high position, allowing the pathogen to descend into the middle, reaching the Yin regions, and attaching to tangible, substantial organs. If this is not removed quickly, it will damage the Yin. At this point, the pathogen becomes a "guest pathogen" and must be expelled immediately; this constitutes treating the guest pathogen with urgency.
Regarding the treatment of the "host" (primary condition) requiring slowness: this implies that Yang pathogens reside above and Yin pathogens below, each belonging to their respective home meridians. If one attempts to remove them hastily, it will not only fail to resolve the complexity but also cause further chaos; hence, treating the host requires a slow approach. Regarding the treatment of the "guest" (secondary/interfering condition) requiring urgency: this refers to situations where the Yang aspect receives Yang pathogens and the Yin aspect receives Yin pathogens (these are hosts); conversely, when the Yin aspect receives Yang pathogens or the Yang aspect receives Yin pathogens, these are guests. All so-called guest pathogens should be removed urgently; this constitutes treating the guest pathogen with urgency.
For example, in diseases involving the Shaoyang and Yangming meridians: if the Shaoyang is affected, symptoms manifest around the ears; if the Yangming is affected, there is massive swelling of the head and face. Initially, use Huang Qin (Scutellariae Radix), Huang Lian (Coptidis Rhizoma), and Gan Cao (Glycyrrhizae Radix et Rhizoma), all stir-fried together, decocted, and sipped continuously. After finishing this, one may administer Da Huang (Rhei Radix et Rhizoma), either wine-soaked or baked, along with Niu Bang Zi (Arctii Fructus) stir-fried until fragrant, and Mang Xiao (Natrii Sulfas), all in equal parts. These should also be sipped slowly, preferably after meals, aiming for slight bowel movement. Once the pathogen is eliminated, continue only with the initial formula. If the condition persists, switch to the second formula, following the sequence previously described, aiming for thorough bowel evacuation, and stop once the pathogen is gone. If thirst occurs due to Yangming involvement, add Gua Lou Gen (Trichosanthis Radix). If the pathogen traverses the Yangming channel, add Sheng Ma (Cimicifugae Rhizoma), Ge Gen (Puerariae Lobatae Radix), and Bai Shao (Paeoniae Radix Alba). If the pathogen traverses the Taiyang channel, add Qiang Huo (Notopterygii Rhizoma et Radix), Fang Feng (Saposhnikoviae Radix), and Jing Jie (Schizonepetae Spica). Select and add these appropriately, dividing them equally with the main prescription; do not use powder formulations exclusively.