俗呼黑附子
地胆为之使。畏防风、甘草、人参、黄 、黑豆、绿豆、乌韭、童溲、
犀角。恶蜈蚣。忌豉汁。大辛，大热。有大毒。入手少阴经，通行十二经络。主六腑沉寒，
回三阴厥逆。雄壮悍烈之
性，斩关夺门之气，非大寒直中阴经，及真阳虚散几脱，不宜轻用。引补气药，追复失散之
元阳。引补血药，滋养不足之真阴。引发散药，驱逐在表之风寒。引温暖药，祛除在里之冷
湿。得蜀椒、食盐，下达命门。配干姜，治中寒昏困。配黑山栀，治寒疝诸痛。配生姜，治
肾厥头痛。配肉果粥丸，治脏寒脾泄。配白术，治寒湿。配半夏、生姜，治胃中冷痰。配泽
泻、灯心，治小便虚秘。（两尺脉沉微者可用。）配 石膏等分为末，入麝香少许，茶酒任下
，治头痛。合荆芥，治产后螈 。（生用为宜。若血虚生热、热生风者，投之立毙。）合肉桂
，补命门相火。童便浸，粗纸包煨熟，去皮、脐，切块，再用川连、甘草、黑豆、童便煎汤，
乘热浸透，晒
干用。或三味煎浓汁，去渣，入附子煮透用。回阳，童便制。壮表，面裹煨。一法或蜜炙用
，或蜜煎用。中其毒者，生甘草、犀角、川连，煎汤服之可解。
怪症∶两足心凸肿，头黑硬如钉，胫骨生碎孔，骨髓流出不止，身发寒颤，但思吃酒，
不想
饮食，此肝肾冷热相吞也。用制附子研末调涂，内服韭子汤，效。
世人仅见阳虚无热者，投之有起死之功，而不知阴虚火动者，下咽无救死之法。何竟以
附子
为补剂，虚弱者非此不可。因见水亏火炎，滋阴多不见效，动以为寒凉伤胃，温补可除大热
，必须参、附，然后见功。凉补既久，暂投一二，或者暂觉爽健。岂知内火一起，变害非常
，即使复进凉补，求日前之安泰而不可得。又见伤寒阳症，时疫火症，大半手足厥逆，舌苔
粉白，喜热饮，大恶寒凉，错认为内真寒、外假热，进附、桂以助命门之火，且曰浮游之火
，附、桂引之，而火自归元，因之枉杀人命，不可胜指。
俗称为黑附子。
地胆是它的引经药（使药）。它畏惧防风、甘草、人参、黄芩、黑豆、绿豆、乌韭、童便（儿童尿液）、犀角。它厌恶蜈蚣。忌与豆豉汁同用。
味大辛，性大热。有大毒。归入手少阴心经，通行十二经络。主治六腑深层的寒邪，挽回三阴经的厥逆证。其雄壮悍烈的药性，具有斩关夺门的强劲气势，如果不是大寒之邪直中阴经，以及真阳虚散即将脱失的情况，不宜轻易使用。它能引导补气药，追回复失去散的元阳；引导补血药，滋养不足的真阴；引导发散药，驱逐在体表的风寒；引导温暖药，祛除在体内的冷湿。
得到蜀椒、食盐的配合，能下达命门。配伍干姜，治疗中寒导致的昏困。配伍黑山栀，治疗寒疝及各种疼痛。配伍生姜，治疗肾厥引起的头痛。配伍肉果粥丸，治疗脏寒脾泄。配伍白术，治疗寒湿。配伍半夏、生姜，治疗胃中的冷痰。配伍泽泻、灯心草，治疗小便虚秘。（两尺脉沉微者可以使用。）配伍石膏等分为末，加入少许麝香，茶或酒送服，治疗头痛。合用荆芥，治疗产后抽搐痉挛。（生用为宜。如果是血虚生热、热极生风的情况，服用此药会立即致死。）合用肉桂，补益命门相火。
炮制方法：用童便浸泡，粗纸包裹煨熟，去皮和脐，切块，再用川黄连、甘草、黑豆、童便煎汤，趁热浸透，晒干使用。或者将这三味药煎成浓汁，去渣，放入附子煮透使用。回阳救逆用童便制。固表止汗用面裹煨。另一种方法是用蜜炙或用蜜煎。
如果中毒，可以用生甘草、犀角、川黄连煎汤服用以解毒。
怪症：两足心凸出肿胀，头部黑硬如钉，胫骨生出碎孔，骨髓流出不止，身体发冷颤抖，只想喝酒，不想饮食，这是肝肾冷热相互吞噬的病机。用制附子研末调涂患处，内服韭子汤，有效。
世人只看到阳气虚无热的情况，投用附子有起死回生的功效，却不知道阴虚火动的情况，一旦下咽就没有救死的方法。为什么竟然把附子当作补剂，认为虚弱者非此不可？因为见到水亏火炎，滋阴多不见效，动不动就认为是寒凉药伤了胃，认为温补可以除大热，必须用人参、附子才能见效。凉补既久，暂时投用一二剂，或许暂时觉得爽快健壮。哪里知道内火一起，变害非常严重，即使再进服凉补，也求不到日前那样的安泰了。又见到伤寒阳症、时疫火症，大半出现手足厥逆，舌苔粉白，喜热饮，大恶寒凉，错认为是内真寒、外假热，进用附子、肉桂以助命门之火，还说这是浮游之火，用附子、肉桂引导它，火自然归元，因此枉杀人命，数不胜数。
Commonly referred to as Hei Fuzi (Black Prepared Aconite Root).
Di Dan (Radix Bungeae) serves as its guiding herb (Shi Yao). It is incompatible with Fang Feng (Saposhnikoviae Radix), Gan Cao (Glycyrrhizae Radix et Rhizoma), Ren Shen (Ginseng Radix), Huang Qin (Scutellariae Radix), Hei Dou (Sojae Semen Nigrum), Lv Dou (Phaseoli Radiatus), Wu Jiu (Allium victorialis var. platyphyllum), Tong Piao (Child's Urine), and Xi Jiao (Rhinocerotis Cornu). It is adverse to Wu Gong (Scolopendra). It is contraindicated with Chi Zhi (Fermented Soybean Juice).
It is extremely pungent in flavor and extremely hot in nature. It possesses great toxicity. It enters the Hand-Shaoyin Heart Meridian and circulates through the Twelve Meridians. It primarily treats deep-seated cold in the Six Fu Organs and reverses Jue Ni (cold extremities due to Yang deficiency) of the Three Yin meridians. Its potent, fierce, and vigorous nature possesses the momentum of breaking through gates and passing barriers; it should not be used lightly unless there is direct invasion of severe cold into the Yin meridians or true Yang deficiency with impending collapse. It guides Qi-tonifying herbs to retrieve and restore scattered Yuan Yang (Primordial Yang); it guides Blood-nourishing herbs to nourish deficient True Yin; it guides dispersing herbs to expel Wind-Cold from the exterior; it guides warming herbs to dispel Cold-Dampness from the interior.
Combined with Shu Jiao (Zanthoxylum bungeanum) and Shi Yan (Rock Salt), it directs action downward to the Ming Men (Gate of Life). Paired with Gan Jiang (Zingiberis Rhizoma), it treats coma and drowsiness caused by middle Jiao cold. Paired with Hei Shan Zhi (Gardeniae Fructus processed with bran), it treats Han Shan (Cold Hernia) and various pains. Paired with Sheng Jiang (Zingiberis Rhizoma Recens), it treats Tou Tong (Headache) caused by Kidney Jue. Paired with Rou Guo Zhou Wan (Myristica Seed Porridge Pills), it treats Zang Han Pi Xie (Visceral Cold Spleen Diarrhea). Paired with Bai Zhu (Atractylodis Macrocephalae Rhizoma), it treats Han Shi (Cold-Dampness). Paired with Ban Xia (Pinelliae Rhizoma) and Sheng Jiang, it treats Cold Tan (Cold Phlegm) in the Stomach. Paired with Ze Xie (Alismatis Rhizoma) and Deng Xin Cao (Junci Medulla), it treats Xu Mi (Deficiency-type urinary retention) (Can be used when both Chi pulses are deep and faint). Paired with Shi Gao (Gypsum Fibrosum) in equal parts, ground into powder, with a small amount of She Xiang (Moschus) added, taken with tea or wine, it treats Headache. Combined with Jing Jie (Schizonepetae Herba), it treats Chan Zheng (Convulsions) postpartum (Raw use is suitable. If caused by Blood deficiency generating Heat, and Heat generating Wind, administration will lead to immediate death). Combined with Rou Gui (Cinnamomi Cortex), it tonifies the Minister Fire of the Ming Men.
Processing method: Soak in Tong Bian (Child's Urine), wrap in coarse paper, and bake until cooked. Remove skin and navel, cut into pieces. Then soak thoroughly while hot in decoction of Chuan Lian (Coptidis Rhizoma), Gan Cao, Hei Dou, and Tong Bian, then dry in the sun for use. Alternatively, boil the three ingredients into a thick decoction, remove dregs, add Fuzi, and cook thoroughly for use. For rescuing Yang, process with Tong Bian. For stabilizing the exterior, bake wrapped in flour paste. Another method involves honey-frying or honey-cooking.
If poisoned, it can be detoxified by drinking decoction of Sheng Gan Cao (Raw Licorice Root), Xi Jiao, and Chuan Lian.
Strange Syndrome: The soles of both feet are convex and swollen; the head is black and hard like a nail; fragmented holes appear on the tibia bones with unceasing leakage of bone marrow; the body shivers with cold; there is a craving for alcohol but no desire for food. This is a condition where Liver and Kidney Cold and Heat devour each other. Apply powdered prepared Fuzi externally mixed with a medium, and internally administer Jiu Zi Tang (Leek Seed Decoction). Effective.
The world only sees cases of Yang deficiency without Heat, where administering Fuzi has the power to revive the dying, but does not know that in cases of Yin deficiency with stirring Fire, once swallowed, there is no method to save from death. Why is Fuzi regarded as a tonic, considered indispensable for the weak? Because one observes that Water deficiency leads to flaming Fire, and Yin-nourishing methods often fail, leading people to mistakenly believe that cold-natured herbs damage the Stomach, and that warming tonification can eliminate severe Heat, requiring Ren Shen and Fuzi to see results. After prolonged cooling tonification, temporarily administering one or two doses might bring temporary relief and vigor. Who knows that once internal Fire arises, the harm is extraordinary; even if cooling tonification is resumed, the previous state of peace and health cannot be retrieved. Furthermore, observing Tai Yang disease Yang syndromes and epidemic Fire syndromes, where most present with cold extremities, pink-white tongue coating, preference for hot drinks, and aversion to cold, they are mistaken for True Cold inside and False Heat outside. Administering Fuzi and Rou Gui to assist the Ming Men Fire, claiming it is floating Fire that will return to its origin under the guidance of Fuzi and Rou Gui, thus causing countless wrongful deaths.