甘，苦，微温，无毒。散血止痛，去瘀消肿。治一切吐血衄血，血痢血崩。为金疮杖疮
要药
生广西南丹诸州番峒深山中。根黄黑色，团结者，略似白芨。长者如老干地黄，有节。
以末
掺猪血中，血化为水者真也。近传一种草，苗高三四尺，叶似菊艾而劲浓，有歧尖。茎有赤
棱，夏秋小花如金丝可爱。根大如牛蒡，与南中来者不类，治金疮与一切血症甚效，云是三
七，未知何物。
吐衄，米汤下。（验方第一。）
血痢，为末，米泔下。（第二。）
大便血，为末，白酒下。（第三。）
血崩。同上。（第四。）
赤眼，磨汁涂眼四围。（第五。）
产后血多，为末，米汤下。（第六。）
无名痈肿，醋磨敷即散，已溃者干掺。（第七。）
虎蛇伤，为末，米饮下三钱，仍嚼敷之。（第八。）
去净毛，浆水浸焙用。生用入心，醋炙入肝胆，酒炙上行。黄芩、龙骨、理石为使,
恶菊花、元参、鲜皮、芫花、僵蚕，畏冬花、牛膝，胜乌头，解巴豆毒。忌猪肉，恶冷
水。
大苦，大寒，无毒。手少阴心经药也。清心退热，泻火除烦，镇肝凉血，解渴止汗。浓
肠胃
而止泻痢，开伏梁而泻痞满，解痈疽疮疥之毒，退目痛及 伤之火。虚寒者勿用。舌苔红者
急用之。产后忌之。
生巫阳川谷及蜀郡太山之阳。二八月采。苏颂《图经》曰∶今江、湖、荆、夔州郡亦有，
而
以宣城九节坚重相击有声者为胜，施、黔者次之，东阳、歙州、处州者又次之。苗高尺许，
叶似甘菊，四月开黄花，六月结实似芹子色黄。其苗经冬不凋。汉末本草，惟取蜀郡黄肥而
坚者为胜，唐时以澧州者为胜，今则雅州、眉州者为良。药物之兴废不同若此。
小儿口疮，同干姜为末掺之。（验方第一。）
消渴尿多，蜜丸服。又同花粉丸服。又入猪肚
白淫，脉数有热，同茯苓丸服。（第三。）
赤痢已久，为末，鸡子
（第四。）
热毒血痢，水煎一两，露一宿，空腹服。（第五。）
热毒赤痢，同当归焙末，入元香少许，米汤下二钱。（第六。）
赤白痢久，并无寒热，同乌梅烧末，米汤下。（第七。）
赤白暴痢，如鹅鸭肝，痛甚，同黄芩各一两煎热服。（第八。）
一切诸痢，不问冷热赤白，谷滞休息。黄连两半，龙骨一两，真附子八钱，干姜一两，
先以水两
盅入铜器中，火沸取下着土上，沸止又入水两盅，如此九次；纳诸药入水内，再煎沸，辄取
下，沸止
又上火，如此九次，可得二三盅，顿服即止。（第九。）
下痢腹痛，赤白下重，酒煎两服。（第十。）
小儿久痢赤白有火，水煎，蜜合服五次。（十一。）
脏毒下血，净连半斤，入猪大肠内，砂釜煮烂，取连焙末，捣肠合丸，米汤下。（十二。）
赤白痢，日夜无度，同吴茱萸各二两，同炒香，各为末，以米饭合丸豆大，每服三十丸。
赤痢甘
草汤下黄连丸，白痢生姜汤下吴茱萸丸，各十五丸。赤白痢并服，米汤下，甚效。（十三。）
肠风。同上。（十四。）
脾积食泻，捣蒜合丸豆大，白汤下五十丸。（十五。）
痢痔肠脱，为末，冷水合敷之。（十六。）
鸡冠痔疾，为末敷之。（十七。）
痔病秘结，同枳壳丸服。（十八。）
暴赤目痛，同干姜、杏仁为末，绵包浸汤，闭目乘热洗之。（十九。）
小儿赤目，水合敷足心。（二十。）
烂弦风眼，黄连十文，槐花、轻粉少许，为末，男儿乳合之，饭上蒸过，帛包之，熨目
三四次。（二十一。）
目猝痒痛，乳汁浸点，诸目悉治。（二十二。）
泪出不止，水浸浓汁渍拭之。（二十三。）
口舌生疮，酒煎时含。（二十四。）
小儿鼻 ，鼻下两道赤色，有疳，以米泔洗之，黄连末敷之。（二十五。）
小儿月蚀生耳后，为末敷之。（二十六。）
小儿食土，取好黄土煎黄连渍之，晒干与食。（二十七。）
腹中儿哭，煎浓汁呷之。妇科胎哭是也。（二十八。）
子烦、口干不卧，为末，粥下一钱。（二十九。）
痈疽肿毒，已溃未溃皆可，同槟榔末、鸡子清合敷。（三十。）
中巴豆毒利不止，同干姜末水下。（三十一。）
心火实热，水煎服。（三十二。）
心猝热痛，水煎服。（三十三。）
阳毒狂奔，同石膏末，甘草水下。（三十四。）
骨节积热黄瘦，童尿浸，水煎服。（三十五。）
小儿疳热流注，通身疮蚀，或潮热，肚胀作渴，以黄连五两入猪肚中，铺糯米上蒸烂，
捣千杵丸服。（三十六。）
呕烦心热，黄连五分，干姜三分。（三十七。）
中热邪毒，同巴豆吐之。（三十八。）
香连丸 黄连 木香
蜜丸豆大，每白汤下三十。治赤白诸痢，里急腹痛。（诸方第一。）
赴筵散 黄连 干姜
为末掺之。治口疮。（第二。）
黄连汤 黄连 桂枝 炙草 人参 半夏 姜 枣
治腹痛欲呕，心热甚者。（第三。）
黄连阿胶汤 黄连 阿胶 黄芩 白芍 鸡子黄
治心烦不眠。（第四。）
黄连粉 黄连为末。
水合敷。治浸淫疮。（第五。）
下痢赤白，黄苔，便赤，脉数。黄连（五分） 白芍（一钱五分） 苦参（一钱） 当
归（一钱五
分） 枳壳（一钱五分） 甘草（一钱） （第六）
味甘，味苦，性微温，无毒。具有散血止痛、去除瘀血、消除肿胀的功效。治疗各种吐血、鼻出血、便血（痢疾带血）、崩漏（非经期大量阴道出血）。是治疗金疮（金属利器造成的创伤）和杖疮（杖刑造成的创伤）的重要药物。
生长于广西南丹等州的少数民族聚居的深山之中。根部呈黄黑色，团聚成块的，形状略似白芨；长条状的像老干地黄，有节。将黄连研成粉末掺入猪血中，若血液化为水状，即为真品。近来流传一种草，苗高三四尺，叶子像菊艾但更强劲浓密，叶尖有分歧。茎上有红色的棱，夏秋季节开出如金丝般可爱的小花。根部大如牛蒡，与从南方来的黄连不相似，治疗金疮和各种血症非常有效，号称是三七，但不知是什么植物。
治疗吐血、鼻衄，用米汤送服药末。（验方第一。）
治疗血痢，研为粉末，用淘米水送服。（第二。）
治疗大便下血，研为粉末，用白酒送服。（第三。）
治疗崩漏。同上。（第四。）
治疗红眼病，磨取汁液涂抹眼睛四周。（第五。）
产后失血过多，研为粉末，用米汤送服。（第六。）
无名肿毒，用醋磨药敷贴即可消散，已溃破的用干粉撒敷。（第七。）
虎蛇咬伤，研为粉末，用米饮送服三钱，并嚼碎敷在伤口上。（第八。）
去掉净毛，用浆水浸泡后焙干使用。生用入心经，醋炙入肝胆经，酒炙上行。黄芩、龙骨、理石作为引经药；厌恶菊花、玄参、鲜皮、芫花、僵蚕；畏惧冬花、牛膝；能克制乌头，能解巴豆毒。忌食猪肉，厌恶冷水。
味大苦，性大寒，无毒。是手少阴心经的药物。清心退热，泻火除烦，镇肝凉血，解渴止汗。厚肠胃而止泻痢，开伏梁（腹内结块）而泻痞满，解痈疽疮疥之毒，退目痛及伤寒之火。虚寒体质者勿用。舌苔红者急用之。产后忌用。
生长在巫阳川谷及蜀郡太山的南坡。二八月采收。苏颂《图经》说：现在江、湖、荆、夔州郡也有，但以宣城九节坚重相击有声的为优，施州、黔州的次之，东阳、歙州、处州的又次之。苗高一尺左右，叶子像甘菊，四月开黄花，六月结籽像芹子色黄。其苗经冬不凋谢。汉末的本草书，只取蜀郡黄肥而坚的为优，唐代以澧州的为优，现在则以雅州、眉州的为良。药物的兴衰变化如此不同。
小儿口疮，与干姜研为粉末撒敷。（验方第一。）
消渴尿多，制成蜜丸服用。又可与花粉制成丸剂服用。又加入猪肚中。
白淫，脉数有热，与茯苓制成丸剂服用。（第三。）
赤痢日久，研为粉末，用鸡蛋（配合服用）。（第四。）
热毒血痢，用水煎煮一两，露置一夜，空腹服用。（第五。）
热毒赤痢，与当归焙干研末，加入少许元香，用米汤送服二钱。（第六。）
赤白痢久，并无寒热症状，与乌梅烧成粉末，用米汤送服。（第七。）
暴发性赤白痢，状如鹅鸭肝，疼痛剧烈，与黄芩各一两煎热服用。（第八。）
各种痢疾，不论冷热赤白，谷滞休息痢。黄连半两，龙骨一两，真附子八钱，干姜一两，先用水两盅放入铜器中，煮沸后取下放在土上，停止沸腾后再加水两盅，如此重复九次；将诸药放入水中，再煎沸，随即取下，停止沸腾后又上火，如此重复九次，可得二三盅，顿服即止。（第九。）
下痢腹痛，赤白下重，用酒煎服两次。（第十。）
小儿久痢赤白有火，用水煎煮，加蜂蜜合服五次。（十一。）
脏毒下血，净黄连半斤，放入猪大肠内，砂锅煮烂，取出黄连焙干研末，捣烂肠肉合丸，用米汤送服。（十二。）
赤白痢，日夜无度，与吴茱萸各二两同炒香，分别研末，以米饭合丸如豆大，每服三十丸。赤痢用甘草汤送服黄连丸，白痢用生姜汤送服吴茱萸丸，各十五丸。赤白痢并服，用米汤送服，效果甚佳。（十三。）
肠风。同上。（十四。）
脾积食泻，捣蒜合丸如豆大，用白开水送服五十丸。（十五。）
痢疾痔疮肠脱，研为粉末，用冷水调和敷之。（十六。）
鸡冠痔疾，研为粉末敷之。（十七。）
痔病秘结，与枳壳制成丸剂服用。（十八。）
暴赤目痛，与干姜、杏仁研为粉末，用棉包裹浸汤，闭目乘热洗之。（十九。）
小儿红眼，用水调和敷足心。（二十。）
烂弦风眼，黄连十文，槐花、轻粉少许，研为粉末，用男婴乳汁调和，饭上蒸过，用帛包之，熨眼三四次。（二十一。）
眼睛突然痒痛，用乳汁浸泡点眼，各种眼病均可治疗。（二十二。）
泪出不止，用水浸泡浓汁擦拭。（二十三。）
口舌生疮，酒煎时含漱。（二十四。）
小儿鼻塞，鼻下两道赤色，有疳症，用米泔水洗之，黄连末敷之。（二十五。）
小儿月蚀生耳后，研为粉末敷之。（二十六。）
小儿食土，取好黄土煎黄连渍之，晒干给患儿吃。（二十七。）
腹中儿哭，煎浓汁呷之。妇科胎哭即是此症。（二十八。）
子烦、口干不卧，研为粉末，用粥送服一钱。（二十九。）
痈疽肿毒，已溃未溃皆可，与槟榔末、鸡蛋清合敷。（三十。）
中巴豆毒利不止，与干姜末用水送服。（三十一。）
心火实热，用水煎服。（三十二。）
心脏突然热痛，用水煎服。（三十三。）
阳毒狂奔，与石膏末、甘草末用水送服。（三十四。）
骨节积热黄瘦，用童尿浸泡，用水煎服。（三十五。）
小儿疳热流注，通身疮蚀，或潮热，肚胀作渴，以黄连五两放入猪肚中，铺糯米上蒸烂，捣千杵丸服。（三十六。）
呕烦心热，黄连五分，干姜三分。（三十七。）
中热邪毒，与巴豆同用催吐。（三十八。）
香连丸：黄连、木香。蜜丸如豆大，每次用白开水送服三十丸。治疗赤白诸痢，里急腹痛。（诸方第一。）
赴筵散：黄连、干姜。研为粉末撒敷。治疗口疮。（第二。）
黄连汤：黄连、桂枝、炙甘草、人参、半夏、姜、枣。治疗腹痛欲呕，心热甚者。（第三。）
黄连阿胶汤：黄连、阿胶、黄芩、白芍、鸡子黄。治疗心烦不眠。（第四。）
黄连粉：黄连研为粉末。用水调和敷。治疗浸淫疮。（第五。）
下痢赤白，黄苔，便赤，脉数。黄连（五分） 白芍（一钱五分） 苦参（一钱） 当归（一钱五分） 枳壳（一钱五分） 甘草（一钱） （第六）
Taste is sweet and bitter, nature is slightly warm, non-toxic. It disperses blood, relieves pain, removes stasis, and reduces swelling. It treats all types of hematemesis (vomiting blood), epistaxis (nosebleed), bloody dysentery, and metrorrhagia (uterine bleeding). It is an essential medicine for treating metal weapon wounds and cane injuries.
It grows in the deep mountains of Fan Dong (ethnic minority areas) in various prefectures such as Nandan, Guangxi. The root is yellow-black; those that are clustered resemble Baiji (Bletilla striata); the long ones resemble aged dried Rehmannia root, with nodes. If powdered Huanglian is mixed into pig's blood and the blood turns into water, it is genuine. Recently, a type of herb has been circulated: its seedling is three to four chi high, leaves resemble Chrysanthemum mugai but are stronger and denser, with bifid tips. The stem has red ridges, and in summer and autumn, small flowers like golden threads appear, which are lovely. The root is as large as Arctii Fructus (Niu Bang Zi), unlike the one from the south. It is very effective for treating metal wounds and all kinds of blood diseases, claimed to be Sanqi (Notoginseng), but its identity is unknown.
For hematemesis and epistaxis, take the powder with rice soup. (Verified Formula No. 1.)
For bloody dysentery, take the powder with rice wash water. (No. 2.)
For blood in stool, take the powder with white wine. (No. 3.)
For metrorrhagia. Same as above. (No. 4.)
For red eye, grind into juice and apply around the eyes. (No. 5.)
For excessive postpartum blood loss, take the powder with rice soup. (No. 6.)
For nameless carbuncles and swellings, grind with vinegar and apply; if ulcerated, sprinkle dry powder. (No. 7.)
For tiger or snake bites, take three qian of powder with rice drink, and chew and apply to the wound. (No. 8.)
Remove clean hairs, soak in浆水 (fermented rice water) and bake before use. Raw use enters the Heart meridian; vinegar-processed enters the Liver and Gallbladder meridians; wine-processed moves upward. Huangqin (Scutellariae Radix), Longgu (Fossilia Ossis Mastodi et Ossis Cruris), and Lishi (Petroserpenti Herba) act as guides. It is incompatible with Juhua (Chrysanthemi Flos), Xuanshen (Scrophulariae Radix), Xianpi (Akebiae Caulis), Yuanhua (Genkwa Flos), and Jiangcan (Bombyx Batryticatus). It fears Donghua (Adenophorae Radix) and Niuxi (Achyranthis Bidentatae Radix). It overcomes Wutou (Aconiti Radix) and resolves Bidou toxicity. Avoid pork; dislike cold water.
Taste is extremely bitter, nature is extremely cold, non-toxic. It is a drug for the Hand-Shaoyin Heart meridian. It clears the Heart, reduces fever, drains fire, eliminates irritability, calms the Liver, cools blood, relieves thirst, and stops sweating. It thickens the intestines and stomach, stops diarrhea and dysentery, opens Fuliang (subcutaneous mass) and drains fullness, resolves toxins of carbuncles, ulcers, sores, and scabies, and reduces eye pain and heat from Shanghan (Cold Damage). Do not use for deficiency-cold. Use urgently for red tongue coating. Contraindicated after childbirth.
It grows in the valleys of Wuyang River and on the sunny slopes of Mount Tai in Shu Commandery. Harvested in the second and eighth lunar months. Su Song's "Tu Jing" states: Now there are also varieties in Jiang, Hu, Jing, and Kui prefectures, but those from Xuancheng, nine-joint, hard, heavy, and ringing when struck, are superior. Those from Shi and Qian are next best, followed by those from Dongyang, Shizhou, and Chuzhou. Seedlings are about one chi high, leaves resemble sweet chrysanthemum, bloom yellow flowers in April, bear fruit resembling celery seeds in June, yellow in color. The seedlings do not wither in winter. Late Han materia medica only took the fat and hard ones from Shu as superior; Tang dynasty preferred those from Lizhou; now those from Yazhou and Meizhou are considered good. The rise and fall of drugs vary so much.
For infantile mouth ulcers, mix with Ganjiang (Zingiberis Rhizoma) powder and apply. (Verified Formula No. 1.)
For Xiao Ke (Wasting-Thirst) with polyuria, take as honey pills. Also taken as pills with Huafen (Trichosanthis Radix). Also added to pig stomach.
For Bai Yin (white discharge) with rapid pulse and heat, take with Fuling (Poria) pills. (No. 3.)
For chronic bloody dysentery, take as powder with egg. (No. 4.)
For hot toxin bloody dysentery, decoct one liang in water, expose overnight, take on empty stomach. (No. 5.)
For hot toxin red dysentery, bake Danggui (Angelicae Sinensis Radix) and grind to powder, add a little Yuanxiang (Costi Rhizoma), take two qian with rice soup. (No. 6.)
For chronic red and white dysentery without cold or heat symptoms, burn Wu Mei (Mume Fructus) to powder, take with rice soup. (No. 7.)
For acute red and white dysentery resembling goose/duck liver, severe pain, decoct Huanglian and Huangqin (one liang each) and take hot. (No. 8.)
For all types of dysentery, regardless of cold/heat or red/white, grain stagnation, or lingering dysentery. Take Huanglian (half liang), Longgu (one liang), Zhen Fuzi (Aconiti Lateralis Radix Preparata, eight qian), Ganjiang (one liang). First, put two zhong of water in a copper vessel, boil, remove, place on earth until boiling stops, add another two zhong of water, repeat nine times. Then put all herbs in water, boil again, remove, stop boiling, heat again, repeat nine times. Obtain two to three zhong, take in one dose to stop. (No. 9.)
For dysentery with abdominal pain, red and white discharge, heavy sensation, decoct with wine and take twice. (No. 10.)
For infantile chronic red and white dysentery with fire, decoct in water, mix with honey, take five times. (Eleven.)
For Zang Du (visceral toxin) with blood in stool, take half jin of clean Huanglian, put inside pig large intestine, cook thoroughly in clay pot. Take Huanglian, bake, grind to powder, mash intestine meat, make pills, take with rice soup. (Twelve.)
For red and white dysentery, day and night uncontrollable, stir-fry Wuzhuyu (Evodiae Fructus) with Huanglian (two liang each) until fragrant, grind separately to powder, make pills with rice flour size of beans, take thirty pills per dose. For red dysentery, take Huanglian pills with Licorice Soup; for white dysentery, take Evodia pills with Ginger Soup, fifteen pills each. For both, take with rice soup, very effective. (Thirteen.)
For Chang Feng (wind in intestines). Same as above. (Fourteen.)
For spleen accumulation food diarrhea, crush garlic, make bean-sized pills, take fifty with plain water. (Fifteen.)
For dysentery hemorrhoids and rectal prolapse, make powder, mix with cold water and apply. (Sixteen.)
For chicken-comb hemorrhoids, make powder and apply. (Seventeen.)
For hemorrhoids with constipation, take with Zhike (Aurantii Fructus) pills. (Eighteen.)
For sudden red painful eyes, mix Ganjiang and Xingren (Armeniacae Semen) to powder, wrap in cotton, soak in hot water, close eyes and wash while hot. (Nineteen.)
For infantile red eyes, mix with water and apply to soles of feet. (Twenty.)
For rotting margin wind eye, take ten wen of Huanglian, a little Huaihua (Sophorae Flos) and Qingfen (Calomelas), grind to powder, mix with male infant's milk, steam over rice, wrap in cloth, compress eyes three to four times. (Twenty-one.)
For sudden itchy and painful eyes, soak in breast milk and drop, treats all eye diseases. (Twenty-two.)
For continuous tearing, soak in water, make strong juice, wipe with it. (Twenty-three.)
For mouth and tongue ulcers, decoct with wine and hold in mouth. (Twenty-four.)
For infantile nasal obstruction, red lines under nose, with gan disease, wash with rice wash water, apply Huanglian powder. (Twenty-five.)
For infantile ear eruption behind ear, make powder and apply. (Twenty-six.)
For infantile geophagia, take good yellow soil, decoct Huanglian, soak, dry, give to eat. (Twenty-seven.)
For crying fetus in abdomen, decoct strong juice and sip. This is gynecological fetal crying. (Twenty-eight.)
For Zi Fan (maternal restlessness), dry mouth, inability to sleep, make powder, take one qian with congee. (Twenty-nine.)
For carbuncles, ulcers, swellings, toxic masses, whether ulcerated or not, mix with Binglang (Arecae Semen) powder and egg white, apply. (Thirty.)
For unceasing diarrhea due to Bidou poisoning, take with Ganjiang powder and water. (Thirty-one.)
For excess heat of Heart fire, decoct in water and take. (Thirty-two.)
For sudden heart heat pain, decoct in water and take. (Thirty-three.)
For Yang Du (Yang toxin) with wild running, take with Shigao (Gypsum Fibrosum) powder and Licorice water. (Thirty-four.)
For heat accumulation in bone joints, yellow and emaciated, soak in child's urine, decoct in water and take. (Thirty-five.)
For infantile gan heat flowing through, body-wide ulceration, tidal fever, abdominal distension with thirst, put five liang of Huanglian in pig stomach, cover with glutinous rice, steam until soft, pound thousand times, make pills and take. (Thirty-six.)
For vomiting, irritability, heart heat, Huanglian five fen, Ganjiang three fen. (Thirty-seven.)
For heat toxin invasion, induce vomiting with Bidou. (Thirty-eight.)
Xianglian Wan (Fragrant Connected Pill): Huanglian, Muxiang (Aucklandiae Radix). Honey pills size of beans, take thirty with plain water daily. Treats red and white dysentery, tenesmus, abdominal pain. (All Formulas No. 1.)
Fuyan San (Banquet Attending Powder): Huanglian, Ganjiang. Make powder and apply. Treats mouth ulcers. (No. 2.)
Huanglian Tang (Coptis Decoction): Huanglian, Guizhi (Cinnamomi Ramulus), Zhi Cao (Prepared Licorice), Renshen (Ginseng Radix), Banxia (Pinelliae Rhizoma), Jiang (Zingiberis Rhizoma), Zao (Jujubae Fructus). Treats abdominal pain with desire to vomit, severe heart heat. (No. 3.)
Huanglian Ejiao Tang (Coptis and Donkey-Hide Gelatin Decoction): Huanglian, Ejiao (Colla Corii Asini), Huangqin, Baishao (Paeoniae Radix Alba), Jizi Huang (Yolks of Chicken Egg). Treats irritability and insomnia. (No. 4.)
Huanglian Fen (Coptis Powder): Huanglian ground to powder. Mix with water and apply. Treats Jin Yin Chuang (oozing sores). (No. 5.)
Dysentery with red and white discharge, yellow tongue coating, red urine, rapid pulse. Huanglian (five fen), Baishao (one qian five fen), Kushen (Sophorae Flavescentis Radix, one qian), Danggui (one qian five fen), Zhike (one qian five fen), Gancao (one qian). (Sixth)