产贵州者良。为水银硫黄天然化合物。先取上好者研末。水飞三次或以绢袋盛砂。
用荞麦灰淋汁。煮三伏时取出。流水浸洗过。研粉飞晒。方入药
主治。通血脉。定神志。治惊痫。涂疮疥。辟瘟疫。下死胎。亦能发汗。
更衣丸。朱砂五钱。芦荟七钱。（生用）研极细。好酒少许和丸。梧子大。每服一钱二
分。
好酒或米汤下。治肠胃干燥。大便不通。按此药向以为久服通神不老。其实水银硫黄皆有毒。
修治得法。毒可幸免。否则必至毒发难治。
主治。安神。堕胎。杀虫虱。疗恶疮。 制轻粉法。水银一两。白矾二两。食盐一两。
同研。不见星。铺铁器内。用小乌盆覆之。筛灶灰盐水和。封固盆口。炭打二炷香。取开。
粉升盆上。即成。又法。水银一两。皂矾七钱。白盐五钱。同研。如上升炼。
又法。先以皂矾四两。盐一两。焰硝五钱。共炒黄为曲。水银一两。又曲二两。白矾一
钱。研匀。如上升炼。
轻粉丸。轻粉一钱。雄黄丹砂各二钱半。槐花（炒）龟板（炙）各一两。为末。丸梧子
大。
每服一钱。冷茶下。日二服。七日愈。治梅毒。
又方。轻粉胡桃仁槐花（炒研）龟板（炙）红枣肉各二钱。研捣为丸。分三服。初日鸡
汤下。
二日酒下。三日茶下。治梅毒。又方。水银一两。朱砂雄黄各二钱半。白矾绿矾各二两半。
研匀。罐盛。灯盏盖定。盐泥固济。文武火炼升罐口扫收。每以三钱入乳香没药各五分。洒
太乙膏上贴之。绝效。治痈疽梅毒。
凡服食水银轻粉。虽易收效。然毒窜经络。或口齿肿烂。或筋骨疼痛挛缩。久则溃烂难
愈。致成废疾。或用轻粉堕胎。或服之自尽。其面色必惨青。
治服食中毒溃烂者。内服红枣丸。外敷虾蟆散。（附）红枣丸。红枣三斤。杉木煮熟。
去
皮核。多取杉木灰研细末。捣枣肉为丸。弹子大。每日任意服食。不可间断。又方土茯苓一
两。苡米银花防风白藓皮各一钱。木瓜一钱半。皂荚子四分。水煎服。气虚加人参。血虚加
当归。日三服。
虾蟆散。虾蟆大者一。（眼红腹无八字文者不用。）硫黄三钱。胡椒二钱。纳入口内。将
口捆紧。外裹黄泥。入炭火中烧。泥团红透取出。用碗盖住。俟冷。去泥取虾蟆研末。麻油
调。鸭翎或旧笔蘸敷患处。忌铁器。其他中毒者。用开口花椒。不拘多少。白汤吞下。能裹
之从大便出。又方麻油黄蜜红砂糖搅匀服之。又方。捣萝卜汁饮。又方。取麻油饮之。又方。
多食生荸荠。
凡中毒齿缝出血臭肿者。用贯众三钱黄连二钱。水煎俟温。再加黄连末二分。漱口。 误
入耳中。以黄金枕耳边即出。误入肉内。令筋挛。以金物熨之亦出。
产于贵州的药材品质优良。它是水银和硫黄的自然化合物。首先选取上等的原料研磨成粉末。用水飞法处理三次，或者用绢袋盛装丹砂。
使用荞麦灰淋出的汁液，煮三个“伏”的时间后取出。用流动的清水浸泡冲洗干净，再研磨成粉，经过水飞和晾晒处理后，才可用于入药。
主要功效：疏通血脉，安定神志，治疗惊风癫痫，外涂可治疮疥，辟除瘟疫，促使死胎排出，也能发汗。
更衣丸方：朱砂五钱，芦荟七钱（生用），研磨至极细，加少许好酒调和制成丸剂，大小如梧桐子。每次服用一钱二分，用好酒或米汤送服。治疗肠胃干燥导致的大便不通。按此药过去被认为久服可以通神不老，其实水银和硫黄都有毒性。如果炮制方法得当，毒性可以避免；否则必然导致毒发且难以治疗。
主要功效：安神，堕胎，杀虫虱，治疗恶疮。
制作轻粉的方法：水银一两，白矾二两，食盐一两。共同研磨至不见银色星点。铺在铁器内，用小乌盆覆盖在上面，用筛过的灶灰和盐水调和封口，封固盆口。用炭火煅烧二炷香的时间，取开后，轻粉升腾到盆上，即制成。另一种方法：水银一两，皂矾七钱，白盐五钱。共同研磨，像上述方法一样升炼。又一种方法：先用皂矾四两，盐一两，焰硝五钱，共同炒黄作为“曲”。水银一两，加上曲二两，白矾一钱。研磨均匀，像上述方法一样升炼。
轻粉丸方：轻粉一钱，雄黄、丹砂各二钱半，槐花（炒）、龟板（炙）各一两。研成粉末，制成梧桐子大小的丸剂。每次服用一钱，冷茶送服，每日两次，七日痊愈。治疗梅毒。
另一个方子：轻粉、胡桃仁、槐花（炒后研磨）、龟板（炙）、红枣肉各二钱。研磨捣碎制成丸剂，分三次服用。第一天用鸡汤送服，第二天用酒送服，第三天用茶送服。治疗梅毒。
又一个方子：水银一两，朱砂、雄黄各二钱半，白矾、绿矾各二两半。研磨均匀，装入罐中，用灯盏盖住罐口，用盐泥密封固定。用文武火炼制，待药粉升腾至罐口时扫下收集。每次取三钱，加入乳香、没药各五分，洒在太乙膏上贴敷患处，效果极佳。治疗痈疽、梅毒。
凡是服用或食用水银、轻粉的，虽然容易见效，但毒性会窜入经络，导致口齿肿痛溃烂，或者筋骨疼痛挛缩，时间久了会溃烂难愈，最终导致残疾。或者用轻粉堕胎，或者服用后自尽，其面色必定惨青。
治疗因服用或食用中毒导致溃烂者：内服红枣丸，外敷虾蟆散。（附方）红枣丸：红枣三斤，与杉木一起煮熟，去皮去核，多取杉木灰研磨成细末，将枣肉捣烂制成丸剂，大小如弹珠。每天任意服用，不可间断。另一个方子：土茯苓一两，薏苡仁、金银花、防风、白鲜皮各一钱，木瓜一钱半，皂荚子四分。水煎服。气虚加人参，血虚加当归，每日三次。
虾蟆散：大蛤蟆一只。（眼睛红、腹部没有八字纹的不使用。）硫黄三钱，胡椒二钱。塞入蛤蟆口中，将口捆紧，外面包裹黄泥，放入炭火中烧。直到泥团烧得通红取出，用碗盖住。等冷却后，去掉泥土，取出蛤蟆研磨成粉末。用麻油调匀，用鸭毛或旧笔蘸取涂抹患处。忌用铁器。其他中毒情况：用开口花椒，不拘多少，用白开水吞下，能包裹毒素从大便排出。另一个方子：麻油、蜂蜜、红糖搅匀服用。又一个方子：捣萝卜汁饮用。又一个方子：喝麻油。又一个方子：多吃生荸荠。
凡是中毒导致牙缝出血、口臭肿胀者：用贯众三钱，黄连二钱。水煎至温，再加黄连末二分，用来漱口。误入耳中：用黄金枕头放在耳边即可排出。误入肉内：导致筋脉挛缩，用金属物品熨烫也可排出。
Those produced in Guizhou are of superior quality. It is a natural compound of Hydrargyrum (Mercury) and Sulfur. First, select the finest material and grind it into powder. Perform water levigation three times, or place the Cinnabar in a silk bag.
Pour the juice obtained by leaching buckwheat ash over it, boil for three "Fu" periods, then remove. Soak and rinse thoroughly with running water, then grind into powder, perform water levigation again, and dry in the sun before it can be used in medicine.
Main indications: Promotes blood circulation, calms the spirit, treats convulsions and epilepsy, applies topically to treat sores and scabies, wards off epidemics, expels dead fetus, and can also induce sweating.
Gengyi Wan (Changing Clothes Pill): 5 qian of Zhusha (Cinnabaris), 7 qian of Lvhui (Aloe). (Used raw.) Grind to an extremely fine powder. Mix with a small amount of good wine to form pills, sized like Sophora japonica seeds. Take 1.2 qian per dose. Administer with good wine or rice gruel. Treats constipation due to dryness of the intestines and stomach. Historically, this medicine was believed that long-term use could confer spiritual clarity and immortality; however, both Mercury and Sulfur are toxic. If processed correctly, toxicity can be avoided; otherwise, severe poisoning difficult to treat will inevitably occur.
Main indications: Calms the spirit, induces abortion, kills lice, treats malignant sores.
Method for preparing Qingfen (Calomel): 1 liang of Hydrargyrum (Mercury), 2 liang of Baijian (Alumen), 1 liang of Yanshi (Sodium Chloride). Grind together until no silver specks are visible. Spread inside an iron vessel, cover with a small black earthenware pot. Seal the mouth of the pot with a mixture of sifted stove ash and salt water. Calcine over charcoal fire for the time it takes to burn two incense sticks. Upon opening, the powder rises to the upper pot, completing the preparation. Another method: 1 liang of Hydrargyrum (Mercury), 7 qian of Zaofan (Vitriol), 5 qian of Baishen (White Salt). Grind together and calcine as described above. Yet another method: First, stir-fry 4 liang of Zaofan (Vitriol), 1 liang of Salt, and 5 qian of Yanxiao (Saltpeter) until yellow to create a "qu" (catalyst/medium). Add 1 liang of Hydrargyrum (Mercury), 2 liang of the prepared qu, and 1 qian of Baijian (Alumen). Grind uniformly and calcine as described above.
Qingfen Wan (Calomel Pill): 1 qian of Qingfen (Calomel), 2.5 qian each of Xionghuang (Realgar) and Zhusha (Cinnabar), 1 liang each of Huaihua (Sophorae Flos, stir-fried) and Guijia (Testudinis et Chelonis Carapax et Plastrum, roasted). Grind into powder and form pills sized like Sophora japonica seeds. Take 1 qian per dose with cold tea, twice daily. Cure within seven days. Treats syphilis.
Another prescription: 2 qian each of Qingfen (Calomel), Hutao Ren (Juglandis Semen), Huaihua (Sophorae Flos, stir-fried and ground), Guijia (Testudinis et Chelonis Carapax et Plastrum, roasted), and Hongzaorou (Ziziphi Jujubae Mesocarp). Grind and mash into pills. Divide into three doses. On the first day, administer with chicken broth; on the second day, with wine; on the third day, with tea. Treats syphilis.
Another prescription: 1 liang of Hydrargyrum (Mercury), 2.5 qian each of Zhusha (Cinnabar) and Xionghuang (Realgar), 2.5 liang each of Baijian (Alumen) and Lvfan (Chalcanthite). Grind uniformly, place in a jar, cover with a lamp saucer, seal tightly with salt mud. Refine using mild and strong heat, sweep up the powder rising from the jar mouth. For each application, mix 3 qian with 5 fen each of Ruxiang (Boswelliae Resina) and Moyao (Myrrhae Resina), sprinkle onto Taiyi Gao (Taiyi Plaster), and apply to the affected area. Extremely effective. Treats carbuncles, ulcers, and syphilis.
Whenever Mercury or Calomel is ingested, although effects may appear quickly, the toxin invades the meridians, causing swelling and ulceration of the mouth and teeth, or pain and contracture of muscles and bones. In the long term, this leads to difficult-to-heal ulcers and permanent disability. Alternatively, Calomel may be used to induce abortion, or taken for suicide, resulting in a ghastly cyan complexion.
To treat poisoning and ulceration caused by ingestion: Internally take Hongzao Wan (Red Date Pill); externally apply Hamasan (Toad Powder). (Attached Prescription) Hongzao Wan (Red Date Pill): 3 jin of Hongzao (Ziziphi Jujubae Fructus), boiled with Shanmu (Cupressi Lignum) until cooked. Remove skin and pits. Use abundant Cupressi Lignum ash, grind into fine powder. Mash the date flesh into pills, sized like marbles. Take freely daily without interruption. Another prescription: 1 liang of Tufuling (Smilacis Glabrae Rhizoma), 1 qian each of Yimi (Coicis Semen), Yinhua (Lonicerae Japonicae Flos), Fangfeng (Saposhnikoviae Radix), Baixianpi (Dictamni Cortex), 1.5 qian of Mugua (Chaenomelis Fructus), 4 fen of Zhaojiazi (Gleditsiae Sinensis Spina). Decoct in water. Add Renshen (Ginseng Radix) for Qi deficiency, Danggui (Angelicae Sinensis Radix) for Blood deficiency. Take three times daily.
Hamasan (Toad Powder): One large Toad (Do not use if eyes are red or abdomen lacks a figure-eight pattern). 3 qian of Sulfur, 2 qian of Hujiao (Piperis Longi Fructus). Insert into the toad's mouth, tie the mouth tightly, wrap in yellow mud, and roast in charcoal fire until the mud turns red-hot. Remove, cover with a bowl, and let cool. Remove mud, take out the toad, and grind into powder. Mix with Sesame Oil (May Zhi). Apply to the affected area using a duck feather or old brush. Avoid iron utensils. For other poisonings: Use Kaikou Huajiao (Schisandrae Chinensis Fructus with split husk), any amount, swallow with warm water. It can wrap the toxin and expel it via stool. Another prescription: Mix May Zhi (Sesamum Indicum Oleum), Huangmi (Mel), and Hongshatang (Brown Sugar) evenly and ingest. Another prescription: Drink freshly squeezed Radish Juice. Another prescription: Drink Sesame Oil. Another prescription: Eat plenty of fresh Water Chestnuts.
For poisoning manifesting as bleeding from gum fissures, foul odor, and swelling: Use 3 qian of Guanzhong (Cyrtomii Rhizoma) and 2 qian of Huanglian (Coptidis Rhizoma). Decoct in water, let cool slightly, add 2 fen of Huanglian (Coptidis Rhizoma) powder, and use for rinsing the mouth. If accidentally entered the ear: Place a gold pillow beside the ear to extract it. If accidentally entered the flesh: Causing muscle contracture, apply hot metal objects to extract it.