《时习》云∶疗寒热头疼，温气。童男子者，尤良。
《衍义》云∶人尿，须用童男者，产后温一杯，压下败血恶物。久服，令人反虚。气血
无热，尤不可多服。此亦性寒，故治热劳方中亦用也。
《日华子》云∶小便，凉。止劳渴嗽，润心肺，疗血闷热狂，扑损瘀血，运绝，及蛇犬
等咬，以热尿淋患处。难产胞衣不下，即取一升，用姜、葱煎，乘热饮，即下。
气微寒，味咸，平。无毒。
入足少阴经。
《象》云∶治伤寒寒热温疟，女子带下赤白，止汗，止心痛气结。涩大小肠，治心胁
痞。烧，白研，细用。
《珍》云∶能软积气之痞。《经》曰∶咸能软坚。
《心》云∶咸，平。熬，泄水气。
《本草》云∶主伤寒寒热，温疟洒洒，惊恚怒气。除拘缓，鼠 ，女子带下赤白。除留
热在关节，荣卫虚热，往来不定，烦满。止汗，心痛气结。止渴，除老血。涩大小肠，止大
小便。疗泄精，喉痹咳嗽，心胁下痞热。能去瘰 ，一切疮肿。入足少阴。咸为软坚之剂，
以柴胡引之，故能去胁下之硬；以茶引之，能消结核；以大黄引之，能除股间肿；地黄为之
使，能益精收涩，止小便，本肾经之药也。久服，强骨节，杀鬼延年。贝母为之使。得甘
草、牛膝、远志、蛇床子，良。恶麻黄、吴茱萸、辛夷。
《药性论》云∶君主之剂。治女子崩中，止血及盗汗，除风热，定痛。治温疟。又和杜
仲服，止盗汗。为末蜜丸，服三十丸，令人面光白，永不值时气。又治鬼交精出，病患虚而
多热，加用之，并地黄、小草。
陈士良云∶牡蛎捣粉粉身，治大人小儿盗汗。和麻黄根、蛇床子、干姜为粉，粉身
，去阴汗。《衍义》意同。
《时习》记载：治疗寒热交替、头痛，以及温气病。使用童男童人的尿液，效果尤其好。
《衍义》记载：人尿必须选用童男童人的，产后服用一杯，可以压下败血和恶露等污物。长期服用，反而会导致人体虚弱。如果气血没有热象，尤其不可多服。这也是因为人尿性寒，所以在治疗虚劳发热的方剂中也会使用。
《日华子》记载：小便，性凉。可止住因虚劳引起的口渴咳嗽，滋润心肺，治疗因血热引起的心烦狂躁，以及跌打损伤导致的瘀血、气绝，还有被蛇、狗等咬伤的情况，可用热尿淋洗患处。对于难产、胎盘不下，取一升尿，用生姜、葱白煎煮，趁热饮用，胎盘即可排出。
（牡蛎）气微寒，味咸，平性。无毒。
归入足少阴肾经。
《本草发挥·象》记载：治疗伤寒引起的寒热往来及温疟，女子赤白带下，止汗，缓解心痛和气机郁结。收敛大肠和小肠，治疗心胁部的痞满感。将其烧成灰，研磨成白色细粉使用。
《本草发挥·珍》记载：能够软化积滞之气形成的痞块。《内经》说：咸味能软化坚硬之物。
《本草纲目》记载：主治伤寒寒热、温疟战栗、惊恐愤怒之气。解除拘挛缓急，治疗鼠瘰（淋巴结核），女子赤白带下。清除关节间的余热，营卫虚弱引起的发热，寒热往来不定，心烦胀满。止汗，缓解心痛气结。止渴，清除陈旧瘀血。收敛大小肠，止住大、小便失禁。治疗遗精，喉痹咳嗽，心胁下部痞热。能去除瘰疬，治疗一切疮肿。归入足少阴肾经。咸味是软化坚硬的药剂，借助柴胡作为引经药，所以能去除胁下的硬块；借助茶作为引经药，能消散结核；借助大黄作为引经药，能消除大腿根部的肿胀；以地黄为使药，能益精收涩，止住小便，这是本属于肾经的药物。长期服用，能强健骨节，辟邪延年。以贝母为使药。配合甘草、牛膝、远志、蛇床子使用，效果良好。忌与麻黄、吴茱萸、辛夷同用。
《药性论》记载：作为君药。治疗女子崩漏，止血及盗汗，清除风热，定痛。治疗温疟。又与杜仲配合服用，可止盗汗。制成粉末蜜丸，每次服用三十丸，使人面色光洁白皙，永不感染时行疫病。又治疗鬼交（梦遗滑精）、精气外泄，病患身体虚弱且多热，加入此药，并配合地黄、小草使用。
陈士良记载：将牡蛎捣碎成粉扑在身上，治疗大人小儿的盗汗。与麻黄根、蛇床子、干姜一起制成粉末，扑在身上，可去除阴部出汗。《衍义》的意思与此相同。
*Shi Xi* records: It treats alternating chills and fever, headache, and warm qi disorders. Urine from a prepubescent boy is particularly effective.
*Yan Yi* records: Human urine must be collected from a prepubescent boy; after childbirth, drinking one cup can expel lochia and other foul matter. Long-term consumption may lead to deficiency. If there is no heat in the qi and blood, it should especially not be taken in excess. This is because its nature is cold, so it is also used in formulas treating consumptive fever (lao re).
*Ri Hua Zi* records: Urine is cool in nature. It stops thirst and cough due to consumption, moistens the lungs and heart, treats mania caused by blood-heat, traumatic blood stasis, sudden collapse of vital energy, and bites from snakes or dogs. For these conditions, hot urine should be poured over the affected area. For difficult labor with retained placenta, take one sheng of urine, decoct it with ginger and scallion, and drink it while hot; the placenta will then be expelled.
[Oyster Shell] has a slightly cold qi, salty flavor, and neutral nature. It is non-toxic.
It enters the Foot-Shaoyin Kidney Meridian.
*Xiang* records: It treats alternating chills and fever in Shanghan (cold damage) and Wen Nue (warm malaria), leukorrhea (red and white discharge) in women, stops sweating, and alleviates heart pain and qi stagnation. It astringes the Large Intestine and Small Intestine, and treats epigastric and hypochondriac fullness. When calcined and ground into a fine white powder, it is used externally or internally.
*Zhen* records: It can soften masses formed by stagnant qi. The *Neijing* states: "Salty flavors can soften hardness."
*Xin* records: Salty in flavor, neutral in nature. When roasted, it drains damp-water qi.
*Ben Cao* records: It primarily treats alternating chills and fever in Shanghan, the shivering of Wen Nue, and emotions of fright and anger. It relieves spasms and flaccidity, treats Shu Lou (scrofula/lymphatic tuberculosis), and leukorrhea in women. It clears residual heat in the joints, deficiency heat of Ying and Wei causing alternating chills and fever, restlessness, and fullness. It stops sweating, alleviates heart pain and qi stagnation, quenches thirst, and removes old blood. It astringes the intestines, stopping diarrhea and urinary incontinence. It treats spermatorrhea, bi-syndrome of the throat, cough, and heat-fullness in the chest and hypochondrium. It eliminates Luo Li (scrofula) and all types of sores and swellings. It enters the Foot-Shaoyin Meridian. Salty substances are agents that soften hardness. Guided by Chai Hu (Bupleuri Radix), it can remove hardness in the hypochondrium; guided by tea, it can dissipate tubercles; guided by Da Huang (Rhei Radix et Rhizoma), it can eliminate swelling in the groin; with Di Huang (Rehmanniae Radix) as an assistant, it benefits essence, promotes astringency, stops urination, and acts specifically on the Kidney meridian. Long-term use strengthens bone joints, dispels evil spirits, and prolongs life. Bei Mu (Fritillariae Bulbus) serves as an assistant. It works well when combined with Gan Cao (Glycyrrhizae Radix), Niu Xi (Achyranthis Bidentatae Radix), Yuan Zhi (Polygalae Radix), and She Chuang Zi (Cnidii Fructus). It is incompatible with Ma Huang (Ephedrae Herba), Wu Zhu Yu (Evodiae Fructus), and Xin Yi (Magnoliae Flos).
*Yao Xing Lun* records: It serves as a sovereign drug. It treats metrorrhagia in women, stops bleeding and night sweats, clears wind-heat, and stabilizes pain. It treats Wen Nue. When taken together with Du Zhong (Eucommiae Cortex), it stops night sweats. Made into pills with honey, taking thirty pills per dose makes the complexion bright and white, preventing infection by seasonal epidemic pathogens. It also treats nocturnal emission ("ghost intercourse") and loss of essence; for patients who are deficient and have excessive heat, it is added, along with Di Huang (Rehmanniae Radix) and Xiao Cao (Lithospermi Semen).
Chen Shiliang records: Crushing Oyster Shell into powder and applying it to the body treats night sweats in adults and children. Mixed with Ma Huang Gen (Ephedrae Caulis), She Chuang Zi (Cnidii Fructus), and Gan Jiang (Zingiberis Rhizoma) into a powder and applied to the body, it removes sweating in the genital region. The meaning of *Yan Yi* is consistent with this.