〔 曰〕凡使勿用头粗浓并尾大者，为孔公石，不用。色黑及经大火惊过，并久在地上
收者
者。
方用
筛过
晒干
瓦
〔大明曰〕凡入药烧后水 用之，凝白者佳。〔时珍曰〕凡用火中 赤，酒淬七次，研
细水飞过，日干。亦有用烧酒浸过，同樟脑入罐升炼，取粉用者。
〔 曰〕凡修事一斤，用五花皮一镒，地榆一镒，故绵十五两，三件并锉。于石上捶，
碎作
如尘
〔 曰〕凡使研细，以腊水重重飞过，水面上有赤色如薄云者去之。乃用细茶脚汤煮一
伏时，取出又研一万匝。以净铁铛烧赤，下白蜜蜡一两，待化投新汲水冲之，再煮一二十沸，
取
经
〔弘景曰〕凡用，细研水洮，取汁澄之，勿令有沙土也。〔 曰〕见太一下。
〔 曰〕凡修事，用黑豆五合，黄精五合，水二斗，煮取五升，置瓷锅中，下余粮四两
煮之，旋添，汁尽为度，其药气自然香如新米，捣了，又研一万杵，方用。
〔 曰〕凡使勿用夹石及铜青。每一两要紫背天葵、甘草、青芝草三件，干湿各一镒，
细锉
水浴
〔 曰〕凡使用，以小瓷瓶盛，后入紫背天葵、石龙芮二味，火 从巳至申，便用甘草
水浸，从申至子，出拭干，入瓶再 ，别研三万下用。〔时珍曰〕医家皆言生砒经见火则毒
甚，
乎？
【雷敩曰】凡是使用的，不要用头粗浓和尾大者，那是孔公石，不用。颜色黑以及经过大火惊吓过，并且长久在地上收藏的（砒石），（也不可用）。
【李时珍曰】凡是使用火中烧红，用酒淬炼七次，研细后水飞，晒干。也有用烧酒浸泡过，同樟脑放入罐中升炼，取粉使用的。
【雷敩曰】凡是修制一斤，用五花皮一镒，地榆一镒，旧绵十五两，三件一起锉碎。在石上捶打，碎作如尘。
【雷敩曰】凡是使（用），研细，以腊月水重重飞过，水面上有赤色如薄云者去掉它。乃用细茶脚汤煮一个时辰，取出又研一万匝。用净铁铛烧红，下白蜜蜡一两，待化开投入新汲水冲之，再煮一二十沸，取（其汁/粉）经（久存放或备用）。
【雷敩曰】见太一下。
【雷敩曰】凡是修制，用黑豆五合，黄精五合，水二斗，煮取五升，置瓷锅中，下余粮四两煮之，旋添，汁尽为度，其药气自然香如新米，捣了，又研一万杵，方用。
【雷敩曰】凡是使（用），不要用夹石及铜青。每一两要紫背天葵、甘草、青芝草三件，干湿各一镒，细锉，水浴。
【雷敩曰】凡是使用，以小瓷瓶盛，后入紫背天葵、石龙芮二味，火（煅）从巳至申，便用甘草水浸，从申至子，出拭干，入瓶再（煅），别研三万下用。
【李时珍曰】医家皆言生砒经见火则毒甚，（信）乎？
[Lei Xiao said] When using it, do not use the thick heads and large tails, as these are Konggong Stone (Konggong Shi), which should not be used. Those that are black in color, have been subjected to intense fire heat, or have been stored on the ground for a long time [are also unsuitable].
[Meng Shen said] For medicinal use, after calcining, process with water levigation; those that congeal into a white substance are of superior quality.
[Li Shizhen said] For processing, calcine until red-hot in fire, quench in wine seven times, grind into fine powder, then perform water levigation, and dry in the sun. There is also a method where it is soaked in distilled spirits, combined with Camphora (Zhangnao, 樟脑), placed in a jar, and sublimated to obtain the powder.
[Lei Xiao said] For processing one jin (approx. 500-600g), use one yi (approx. 12-16 taels) of Wuhua Pi (Bark of Five-flower Vine), one yi of Diyü (Radix Sanguisorbae), and fifteen liang of old cotton wool. Cleave all three ingredients together. Pound them on a stone until they are crushed into dust-like particles.
[Lei Xiao said] When using, grind into fine powder, and repeatedly perform water levigation with water from the twelfth lunar month. Discard any reddish film resembling thin clouds floating on the water surface. Then, decoct with strong tea infusion for one shichen (two hours). Remove and grind ten thousand times. Heat a clean iron pan until red-hot, add one liang of White Beeswax (Mila, 白蜜蜡), wait for it to melt, pour in fresh well water to quench, boil again for twenty to thirty cycles, and collect the residue/powder for storage/use.
[Tao Hongjing said] When using, grind finely and wash with water (taoliao), collect the liquid, let it settle, ensuring no sand or soil remains.
[Lei Xiao said] See Taiyi Xia.
[Lei Xiao said] For processing, use five he of Black Soybeans (Heidou, 黑豆) and five he of Polygonatum Rhizome (Huangjing, 黄精), with two dou of water. Decoct until five sheng remain. Place in a porcelain pot, add four liang of Yuliang (Dysosma Verrucosa Root/Rhizome or similar earthy mineral/herb contextually), continue decocting while adding water as needed, until the liquid is exhausted. The medicine will naturally smell fragrant like new rice. Pound it, then grind ten thousand times before use.
[Lei Xiao said] When using, do not use those containing stone impurities or Copper Green (Tongqing, 铜青). For every one liang, use three ingredients: Zi Bei Tian Kui (Omphalodes Verticillata Herb), Glycyrrhizae Radix et Rhizoma (Gancao, 甘草), and Qing Zhi Cao (Green Mushroom Grass), each weighing one yi (dry or wet state). Cleave finely and bathe in water.
[Lei Xiao said] When using, place in a small porcelain bottle. Add two ingredients: Zi Bei Tian Kui (Omphalodes Verticillata Herb) and Shilong Rui (Batrachium Rivulare Herb). Calcine by fire from Si hour (9-11 AM) to Shen hour (3-5 PM). Then soak in Licorice Water (Gancao Shui, 甘草水) from Shen hour (3-5 PM) to Zi hour (11 PM-1 AM). Remove, wipe dry, place back in the bottle, calcine again, and separately grind thirty thousand times before use.
[Li Shizhen said] Physicians all say that raw Arsenic Trioxide (Pishi, 砒石) becomes extremely toxic when exposed to fire. Is this true?