赵嗣真曰详仲景论发汗汤剂各分轻重不同如麻黄桂枝青龙各半越婢等汤各有等差至于少
阴发
汗二汤虽同用麻黄附子亦自有轻重加减之别故以加细辛为重加甘草为轻辛散甘缓之义也其第
一证以少阴本无热此发热故曰反也盖发热为邪在表而当汗又兼脉沉属阴而当温故以附子温经
麻
黄散寒而热须汗解故加细辛是汗剂之重者第一证既无里寒之可温又无里热之可下求其所用麻
黄附子之意则是脉亦沉方可名曰少阴病身亦发热方可行发表药又得之二三日病气尚浅比之前
证亦稍轻故不重言脉证而但曰微发汗所以去细辛加甘草是汗剂之轻者向使脉不沉身不热又无
他证则是无病患也又何药焉仲景本分作两证以别汗剂之轻重活人书却于第二证中除去无证两
字改作常见少阴热阳证者所谓少阴热阳证如经云心中烦不得卧或咽疮声不出者或咳而呕渴或
口燥咽干或腹胀不大便数证皆是也夫岂麻黄附子甘草汤发汗剂所可治耶抑又有闻焉麻黄附子
细辛汤为治少阴病之脉沉反发热者固也而仲景又有四逆汤治太阳病之发热反脉沉者均谓之反
也仲景云病发热头疼脉反沉若不瘥身体头疼痛者当救其里宜四逆汤此证出太阳篇又云少阴病
始得
之反发热脉沉者麻黄附子细辛汤此证出少阴篇
切详太阳病发热头痛法当脉浮今反沉少阴脉沉法当无热今反热仲景于此两证各言反者谓
反常也盖是太阳病脉似少阴少阴病证似太阳所以谓之反而治之异也今深究其旨均是脉沉发热
以其有头痛故为太阳病阳证当脉浮今反不能浮者以里虚久寒正气里微所致又身体疼痛故宜救
里使正气内强逼邪出外而干姜生附亦能出汗而解假使里不虚寒则当见脉浮而正属太阳麻黄
汤证也均是脉沉发热以其无头痛故名少阴病
阴病当无热今反寒邪在表未传在里但皮腠郁闭而为热而在里无病故用麻黄细辛以发表邪之热
附子以温少阴之经假使寒邪入里则外必无热当见吐利厥逆等证而属正少阴四逆汤证也由此观
之表邪浮浅发热之反犹轻正气衰微脉沉之反为重此四逆汤为剂不为不重于麻黄附子细辛汤也
又可见熟附配麻黄发中有补生附配干姜补中有发仲景之旨微矣嗟夫常病用常法夫谁不知设有
证变者或脉变者往往疑似参差亦欲以常法例治之惑矣如仲景所论太阳少阴两证脉沉发热虽同
而受病与用药自别此实证治之奇异医法之玄微故并及之
谨按伤寒六经证仲景例表里六经药矣而又于每经表药中分脉证轻重而用药如此实万世无
穷之
惠也然历世而下得此意例之妙者能几人哉但近世习俗不求其意托时世风土之异或例用气药以
治伤寒表邪逆误多矣沉里证乎论见后发表诸方下
赵嗣真说:详细考察张仲景论述的发汗汤剂,各自分为轻重不同的等级。例如麻黄汤、桂枝汤、大青龙汤、小青龙汤、各半汤、越婢汤等,各有等差。至于少阴病发汗的两首方剂,虽然都使用麻黄和附子,但自然也有轻重加减的区别。所以加入细辛的为重证,加入甘草的为轻证,这是基于辛味发散、甘味缓急的道理。
第一证中,因为少阴本无热,现在出现发热,所以称为“反”。一般来说,发热是邪气在表,应当用汗法;但又兼见脉沉,属于阴证,应当用温法。因此用附子温经,麻黄散寒,而热邪需要通过汗法解除,所以加入细辛,这是发汗剂中的重剂。
第一证既然没有里寒需要温补,也没有里热需要攻下,推求其使用麻黄、附子的用意,则是:只有脉象沉,才可以命名为少阴病;身体也发热,才可以行发表药。而且得病二三日,病气尚浅,比之前的证候稍轻,所以不着重描述脉证,只说“微发汗”。因此去掉细辛、加入甘草,这是发汗剂中的轻剂。
假如脉不沉、身不热,又没有其他证候,那就是没有病患的人,又用什么药呢?张仲景本来将这两证分开,以区别发汗剂的轻重。《活人书》却在第二证中删去了“无证”二字,改作“常见少阴热阳证者”。所谓少阴热阳证,如经文所说:心中烦闷不得卧,或咽喉生疮声音不出,或咳嗽呕吐口渴,或口燥咽干,或腹胀不大便。这些证候,难道是麻黄附子甘草汤这种发汗剂所能治疗的吗?
此外还有听闻:麻黄附子细辛汤确实是治疗少阴病脉沉反发热的方剂。而张仲景又有四逆汤治疗太阳病发热反脉沉的情况,都称之为“反”。
张仲景说:“病发热头疼,脉反沉,如果不痊愈,身体头疼痛的,应当救其里,宜用四逆汤。”此证出自太阳篇。又说:“少阴病始得之,反发热,脉沉者,麻黄附子细辛汤。”此证出自少阴篇。
仔细推敲,太阳病发热头痛,法当脉浮,如今反而脉沉;少阴病脉沉,法当无热,如今反而发热。张仲景在这两证中都言“反”,是指反常。大概是太阳病的脉象似少阴,少阴病的证候似太阳,所以称之为“反”,治疗方法也不同。
现在深入探究其旨意,都是脉沉发热。因为伴有头痛,所以定为太阳病阳证,法当脉浮,如今反而不能浮,是因为里虚久寒,正气内微所致。又因身体疼痛,所以宜救里,使正气内强,逼迫邪气出外,而干姜、生附子也能出汗而解。假如里不虚寒,则应当见脉浮,正属太阳麻黄汤证。
同样是脉沉发热,因为没有头痛,所以名为少阴病阴证,法当无热,如今反而有热。这是因为寒邪在表,未传入里,只是皮毛腠理郁闭而为热,而在里没有病,所以用麻黄、细辛以发表邪之热,用附子以温少阴之经。假如寒邪入里,则外面必然无热,应当见到吐利、厥逆等证,而属于正少阴四逆汤证。
由此观之,表邪浮浅,发热之“反”犹轻;正气衰微,脉沉之“反”为重。这四逆汤作为方剂,不能说重于麻黄附子细辛汤。又可见熟附子配麻黄,发中有补;生附子配干姜,补中有发。张仲景的旨意微妙啊!唉,常病用常法,谁不知道?假设有证变、脉变的,往往疑似参差,也想要用常法来例治,这就迷惑了。如张仲景所论太阳、少阴两证,脉沉发热虽然相同,但受病与用药自然有别。这是实证治疗的奇异医法,医理的玄微,所以一并提及。
谨按:伤寒六经证候,张仲景的条例已涵盖表里六经药物,而又于每经表药中区分脉证轻重而用药,这实在是万世无穷的恩惠。然而历世而下,能懂得此意例妙处的人能有几个呢?只是近世习俗不求其意,托辞时世风土之异,或者例用气药来治疗伤寒表邪,逆误很多。关于沉里证的论述,见后发表诸方之下。
Zhao Sizhen stated: A detailed examination of Zhang Zhongjing’s treatise on sweating-inducing decoctions reveals that they are categorized into varying degrees of heaviness and lightness. For instance, Mahuang Tang (Ephedra Decoction), Guizhi Tang (Cinnamon Twig Decoction), Da Qinglong Tang (Major Green Dragon Decoction), Xiao Qinglong Tang (Minor Green Dragon Decoction), Ge Ban Tang (Half-Volume Decoction), and Yuespi Tang (Tiger-Skin Dispelling Decoction) each have their specific gradations. Regarding the two formulas for inducing sweating in Shaoyin disease (Shaoyin Syndrome), although both utilize Mahuang (Ephedrae Herba) and Fuzi (Aconiti Lateralis Radix Praeparata), there are naturally differences in dosage adjustments indicating severity. Thus, the addition of Xixin (Asari Radix et Rhizoma) denotes a heavier formula, while the addition of Gancao (Glycyrrhizae Radix et Rhizoma) denotes a lighter one, based on the principle that acrid flavors disperse and sweet flavors moderate.
In the first syndrome, since Shaoyin inherently lacks heat, the emergence of fever is termed "fan" (reversed/unexpected). Generally, fever indicates pathogenic factors at the exterior, requiring diaphoresis; however, the concomitant deep pulse (Chen Mai) belongs to Yin, necessitating warming. Therefore, Fuzi warms the meridians, Mahuang disperses cold, and because the heat must be resolved through sweating, Xixin is added. This constitutes a heavy sweating formula.
Since the first syndrome presents no interior cold requiring warming and no interior heat requiring purgation, the rationale for using Mahuang and Fuzai is deduced as follows: only when the pulse is deep can it be named Shaoyin disease; only when the body exhibits fever can exterior-releasing medications be administered. Furthermore, having contracted the disease for two or three days implies the pathogenic qi is still shallow, making this syndrome slightly milder than previous descriptions. Hence, the pulse and syndromes are not heavily emphasized, but rather it states "slightly induce sweating." Consequently, Xixin is removed and Gancao is added, constituting a light sweating formula.
If the pulse were not deep, the body not hot, and no other symptoms present, the individual would be considered free of disease, rendering medication unnecessary. Zhang Zhongjing originally separated these two syndromes to distinguish the heaviness and lightness of sweating formulas. However, *Ren Shu* (The Book of Human Life) deleted the phrase "no symptoms" from the second syndrome and revised it to "commonly seen Shaoyin Heat-Yang syndromes." Such Shaoyin Heat-Yang syndromes include, as per the classic text: mental restlessness and inability to sleep, throat sores with loss of voice, cough with vomiting and thirst, dry mouth and throat, or abdominal distension with constipation. Could such syndromes possibly be treated by Mahuang Fuzi Gancao Tang, a sweating formula?
Furthermore, it is noted that Mahuang Fuzi Xixin Tang is indeed used for Shaoyin disease presenting with a deep pulse and reversed fever. Yet Zhang Zhongjing also employed Sini Tang (Four Reversal Decoction) for Taiyang disease presenting with fever and a reversed deep pulse, referring to both situations as "fan" (reversed).
Zhang Zhongjing stated: "When a patient has fever and headache, but the pulse is reversedly deep, if it does not improve, and body and head pain persist, one should rescue the interior,适宜 Sini Tang." This case appears in the Taiyang Chapter. He further stated: "At the onset of Shaoyin disease, with reversed fever and a deep pulse, use Mahuang Fuzi Xixin Tang." This case appears in the Shaoyin Chapter.
Careful analysis reveals that for Taiyang disease with fever and headache, the pulse should normally be floating (Fu Mai); now it is reversedly deep. For Shaoyin disease, the pulse is deep, and there should normally be no fever; now there is reversed fever. Zhang Zhongjing uses "fan" in both cases to denote abnormality. Essentially, the Taiyang pulse resembles Shaoyin, and the Shaoyin syndrome resembles Taiyang, hence the term "reversed," leading to different treatments.
Upon deeper investigation, both involve deep pulses and fever. Because headache is present, it is classified as a Taiyang Yang syndrome, where the pulse should be floating; the failure to float is due to interior deficiency and chronic cold, causing interior righteous qi to be weak. Due to body pain, rescuing the interior is appropriate to strengthen interior righteous qi, forcing pathogens outward. Dried Ginger (Ganjiang) and Raw Aconite (Sheng Fuzi) can also induce sweating to resolve the condition. If the interior were not deficient and cold, the pulse would be floating, fitting the Taiyang Mahuang Tang syndrome.
Similarly, regarding deep pulse and fever, the absence of headache classifies it as a Shaoyin Yin syndrome, where there should be no fever; the presence of fever occurs because cold pathogens are at the exterior, not yet transmitted to the interior, causing heat due to stagnation in the skin and pores, while the interior remains unaffected. Thus, Mahuang and Xixin are used to release exterior pathogenic heat, and Fuzi is used to warm the Shaoyin meridians. If cold pathogens had entered the interior, there would be no exterior fever, and symptoms such as vomiting, diarrhea, and cold extremities would appear, fitting the standard Shaoyin Sini Tang syndrome.
From this perspective, superficial exterior pathogens with reversed fever represent a milder reversal, whereas weak righteous qi with a deep pulse represents a more severe reversal. It cannot be said that Sini Tang is heavier than Mahuang Fuzi Xixin Tang. Moreover, it demonstrates that Prepared Aconite (Shu Fuzi) paired with Mahuang provides tonification within dispersion, while Raw Aconite paired with Dried Ginger provides dispersion within tonification. Zhang Zhongjing’s intent is subtle. Alas, common diseases are treated with common methods, which everyone knows. However, when syndromes or pulses change, creating ambiguity, attempting to apply common methods leads to confusion. Although Zhang Zhongjing’s Taiyang and Shaoyin syndromes both feature deep pulses and fever, the etiology and treatment differ. This represents the extraordinary method for treating excess syndromes and the profound subtlety of medical theory, warranting inclusion here.
Respectfully noting: Zhang Zhongjing’s principles for the Six Meridians of Cold Damage encompass the drugs for the exterior and interior of all six meridians. By distinguishing the heaviness and lightness of pulses and syndromes within each exterior-releasing category, he provided an enduring benefit for ten thousand generations. Yet, through the ages, how few have grasped the subtlety of these principles? In recent times, customs have neglected seeking the underlying meaning, attributing errors to temporal and geographical differences, or incorrectly using Qi-regulating herbs to treat exterior Cold Damage pathogens, leading to many reversals and mistakes. Discussions on interior-deficient syndromes follow below under the various exterior-releasing formulas.