徐仲光治一儿痘，四日，溏泄无度，四肢厥冷，痘点隐隐，其泻已旬日，此脾虚也。以附子理中汤数剂，
泻减肢温。又以补中益气汤加肉果、官桂，泻止后，竟用补中益气汤调理而愈。
一儿痘九日，色灰白，溏泄，厥逆气惫，阴阳不相顺接，四肢为之厥冷也，用陈氏异功散而愈。
一儿痘过期不敛，便溏安静，四肢少温，但脾气不足，用参、附、芩、陈、甘、芍、山药、木香、肉果治
之，破损不成痂而愈。
一儿痘七日，肢厥减食，乃血热而过服冷剂，以致冰伏也，保元汤加丁、桂、炮姜而愈。
一儿痘六朝，绽突焦紫，烦躁闷乱，喘促厥逆，乃阳毒陷伏，厥深热亦深也。以四顺饮，行二次，诸症悉
平，又清解之而愈。
一儿痘四五日，毒已尽，形色无神，二便自利，四肢厥冷，腹胀发哕，里气虚弱也，稍迟则胃气脱矣。急
以理中汤，连进二服，内气一暖，痘即发光红活，四肢温暖。又以补中益气汤加丁香，哕止而愈。
一儿痘靥后，自言手足冷，及按之而热，夜卧不安。经曰∶外热而内冷者，脾弱也。内热而外冷者，胃弱
也。夜卧不宁，脾阴不足也，用归脾汤而愈。
一儿痘后，手足厥冷，乃脾弱不能旁达四肢，用保元汤加当归、白芍、附子、炮姜而愈。
万密斋治汪氏子，痘靥后，忽然闷绝，目闭口合，令作调元汤加麦冬，浓煎灌之，又与粥汤遂愈。此正气
素弱，邪气方盛，壮火食气，气益弱矣。今邪气既退，正气将生，乃否极泰来之兆，所以戒勿扰乱，待其自苏。
人不知此，卒见闷绝，或呼唤抱持，神气一散，不救者多矣。或谓恐有余毒。曰∶余毒有三，一曰疥，二曰痈，
三曰目赤，未闻有昏瞀也。凡痘疮或出不尽，发不透，或空壳无水，或清水非脓，则有余毒。今起发胖壮，脓
浆饱满，何余毒之有哉？
徐仲光治疗一名患痘疮的幼儿，发病第四天，腹泻无度，四肢冰冷，痘疹点隐约可见。腹泻已经持续十天，这是脾虚所致。给予附子理中汤服用数剂后，腹泻减少，四肢转温。随后又用补中益气汤加肉豆蔻、官桂，待腹泻停止后，继续单用补中益气汤调理而痊愈。
另一名幼儿患痘疮第九天，痘色灰白，腹泻，四肢厥冷，气息疲惫，这是阴阳之气不能顺接，导致四肢厥冷。使用陈氏异功散治愈。
还有一名幼儿痘疮过了期限仍未收靥（结痂），大便溏薄，神情安静，四肢稍温，仅是脾气不足。用人参、附子、黄芩、陈皮、甘草、白芍、山药、木香、肉豆蔻治疗，虽然痘疹破损未能结成痂皮，但也痊愈了。
又一名幼儿患痘疮第七天，四肢厥冷减轻，食欲减退，这是因为血热而过服寒凉药物，导致寒气冰伏于内。使用保元汤加丁香、肉桂、炮姜治愈。
还有一名幼儿患痘疮第六天，痘疹绽开突起，颜色焦紫，烦躁不安，呼吸急促，四肢厥冷，这是阳毒陷伏，厥逆越深，内热也越深。使用四顺饮，服药两次后，所有症状平息，再用清热解表的方法治愈。
又一名幼儿患痘疮四五日，痘毒已尽，但痘形色泽无神，大小便自利（不受控制地排出），四肢厥冷，腹胀并伴有呃逆，这是里气虚弱。如果稍微拖延，胃气就会脱绝。急忙使用理中汤，连续服用两剂，体内阳气回暖，痘疹即发出光泽红活，四肢温暖。随后又用补中益气汤加丁香，呃逆停止而痊愈。
还有一名幼儿痘疮收靥后，自称手脚发冷，但触摸时却是热的，夜间睡眠不安。经书说：“外热而内冷，是脾弱；内热而外冷，是胃弱。”夜间卧睡不宁，是脾阴不足。使用归脾汤治愈。
还有一名幼儿痘疮后，手足厥冷，这是脾弱不能将气血旁达四肢。使用保元汤加当归、白芍、附子、炮姜治愈。
万密斋治疗汪氏的儿子，痘疮收靥后，突然昏闷窒息，眼睛闭合，嘴巴紧闭。让他服用调元汤加麦冬，浓煎后灌服，又喂以米汤，于是痊愈。这是因为正气素来虚弱，邪气正盛，壮火消耗元气，使气更加虚弱。现在邪气已退，正气即将恢复，这是否极泰来的征兆，所以告诫不要惊扰，等待其自行苏醒。人们不了解这一点，突然见到昏闷窒息，或者呼唤抱持，导致神气涣散，大多无法救治。有人说恐怕有余毒。万密斋说：余毒有三种表现，一是疥疮，二是痈肿，三是眼睛发红，没听说过有昏闷窒息的。凡是痘疮如果出不完全，发不透，或者是空壳无水，或者是清水而非脓液，这才有余毒。现在痘疹起发胖壮，脓浆饱满，哪里有残余毒素呢？
Xu Zhongguang treated a child with smallpox. On the fourth day, the child suffered from incessant diarrhea and cold limbs, with the rash spots faintly visible. The diarrhea had persisted for ten days, indicating Spleen deficiency (Spleen deficiency). Several doses of Fuzi Lizhong Tang (Aconite Decoction to Regulate the Middle) were administered, after which the diarrhea decreased and the limbs became warm. Subsequently, Buzhong Yiqi Tang (Decoction to Supplement the Middle and Augment Qi) was used with added Rou Dou Kou (Nutmeg) and Guan Gui (Cinnamon Twig). After the diarrhea ceased, the child recovered completely through continued regulation with Buzhong Yiqi Tang alone.
Another child, on the ninth day of smallpox, presented with grayish-white rash color, diarrhea, cold limbs, and exhausted qi. This indicated that Yin and Yang qi failed to connect smoothly, resulting in cold limbs. Chen Shi Yigong San (Chen’s Extra-Efficacy Powder) was used to cure the condition.
In another case, a child’s smallpox did not crust over after the expected period. The stool was loose, the demeanor was calm, and the limbs were slightly warm. This was merely due to insufficient Spleen qi. Treatment involved Ren Shen (Ginseng Root), Fu Zi (Aconite Lateral Root), Huang Qin (Scutellaria Root), Chen Pi (Tangerine Peel), Gan Cao (Licorice Root), Bai Shao (White Peony Root), Shan Yao (Dioscorea Rhizome), Mu Xiang (Costus Root), and Rou Dou Kou (Nutmeg). Although the lesions remained uncrusted, the child recovered.
Another child, on the seventh day of smallpox, showed reduced limb coldness but decreased appetite. This was caused by blood heat exacerbated by excessive intake of cold-natured medicines, leading to ice-like stagnation. Bao Yuan Tang (Decoction to Protect the Origin) with added Ding Xiang (Clove), Gui Zi (Cinnamon Fruit), and Pao Jiang (Prepared Ginger) cured the condition.
Yet another child, on the sixth day of smallpox, exhibited protruding, scabbed, and dark-purple rashes, restlessness, confusion, panting, and cold limbs. This indicated the entrapment of Yang toxin, where deeper cold limbs correlated with deeper internal heat. Si Shun Yin (Four-Compliance Decoction) was administered twice, resolving all symptoms, followed by clearing and resolving methods to achieve recovery.
In another case, four or five days into smallpox, the toxins were exhausted, but the rash lacked luster. There was involuntary passage of urine and feces, cold limbs, abdominal distension, and hiccups, indicating weakness of interior qi. Delay would have led to the collapse of Stomach qi. Urgently, Lizhong Tang (Regulate the Middle Decoction) was given continuously for two doses. Once internal warmth returned, the rash glowed red and vibrant, and the limbs warmed. Subsequently, Buzhong Yiqi Tang with added Ding Xiang (Clove) stopped the hiccups and cured the patient.
After crusting over, a child complained of cold hands and feet, yet they felt hot to the touch, accompanied by restless sleep at night. The Classics state: "External heat with internal cold indicates weak Spleen; internal heat with external cold indicates weak Stomach." Restless sleep indicates insufficiency of Spleen Yin. Gui Pi Tang (Restore the Spleen Decoction) cured the condition.
Another child suffered from cold hands and feet after smallpox crusting, due to weak Spleen failing to distribute qi and blood to the extremities. Bao Yuan Tang with added Dang Gui (Angelica Sinensis Root), Bai Shao (White Peony Root), Fu Zi (Aconite Lateral Root), and Pao Jiang (Prepared Ginger) cured the condition.
Wan Mizhai treated Wang’s son, who suddenly fainted with closed eyes and clenched jaws after smallpox crusting. He prescribed Tiao Yuan Tang (Decoction to Harmonize the Origin) with added Mai Dong (Ophiopogon Tuber), decocted strongly and force-fed. Porridge water was also given, leading to recovery. This occurred because the righteous qi was inherently weak while pathogenic qi was strong; vigorous fire consumed qi, further weakening it. Now that pathogenic qi has receded and righteous qi is regenerating, this is a sign of turning from adversity to prosperity. Therefore, one must avoid disturbance and wait for spontaneous awakening. People unaware of this often panic upon seeing fainting, calling out or holding the patient, causing the spirit to scatter, resulting in death. Some suggested residual toxins. Wan said: Residual toxins manifest in three ways: scabies, carbuncles, and red eyes. I have never heard of fainting as a symptom of residual toxin. Residual toxin exists only if smallpox eruptions are incomplete, fail to rise fully, form empty shells without fluid, or contain clear water instead of pus. Here, the eruption rose plumply with full pus; how could there be residual toxin?