仲 太阳病三日已发汗若吐若下若温针仍不解者此为坏病桂枝不定与也观其脉证知犯何逆随证治之按逆者谓不
当
汗而汗不当下而下或汗下过甚皆不顺于理故云逆也随证治之者如后云汗后病不解及发汗若下之病仍不解某汤主之之类
是也随证治之一句语活而义广王韩诸家以坏病另作一证而以羊肉汤主之误矣
本太阳病不解转入少阳者胁下硬满干呕不能食往来寒热尚未吐下脉沉紧者与小柴胡汤若以吐下发汗温针谵语柴
胡证罢此为坏病知犯何逆以法治之
赵 仲景论中所谓坏病者以太阳病误汗吐下后虚烦结胸痞气吐后内烦腹胀满等证是也此正谓桂枝不定与小柴胡
汤
证罢者曷尝指异气之病如活人所谓异气为坏病之说仲景又云更感异气变为他病者即索矩所为二气三气杂合为病是也以
其未可定名而非有名四种温病之比故以变病名之且四经温病仲景以为冬伤于寒至春发为温病温病未已重遇于邪变为温
疟风温温毒温疫病未尝坏故以变证名之一曰坏病一曰变证名目自是不同可见异气不为坏病也审矣假如温疟果为坏病则
仲景不言小柴胡汤证罢也请三思焉
是斋方 伤寒阴阳二证不明或投药错误致患人困重垂死七日以后皆可服传者云千不失一用好人参一两去芦薄切
水
一大升于银石器内煎至一盏以新水沉之取冷一服而尽汗不自他出只在鼻梁尖上涓涓如水是其应也妙甚苏韬光云侍郎方
丈尝以救数十人王使君宰清流日卒车申屠行父之子妇产后病时疫一十余日已成坏病偶见问因观其只服人参一味遂安是
时未知有此方偶然暗合耳
海 阳证大汗大下后亡阳于外亡血于内上而津脱下而液脱津液两亡宜以羊肉汤补之矧阴证者岂可不温补哉此与
伤
寒太阳证振摇与真武汤一例外之阳病至此尚温况内之阴候岂得不补耶
韩 产脱血虚者宜用羊肉汤伤寒汗下太过亡阳失血若只用救逆效必迟矣与羊肉汤为效神速病患面色虽见阳是客
热
上焦中下二焦阴气已盛若调得下焦有阳则上焦阳气下降丹田知所归宿矣夫气有高下病有远近证有中外治有轻重各适其
所乃愈故病八九日汗下太过二脉沉细无力多蜷足卧恶听人声皮有粟时战如疟宜羊肉汤主之
羊肉汤方
当归 白芍药 牡蛎( 赤各一两) 生姜(二两) 桂枝(七钱半) 龙骨( 通赤半两) 黑附子(炮皮去脐
四钱)上为粗末每服一两羊肉四两葱白五寸生姜心同锉烂以水五升熬减一半以来滤绞去滓分三服服之按此方阴证宜之
鳖甲散 治伤寒八九日不瘥诸药不效名坏伤寒
鳖甲(醋炙为末) 升麻 前胡 乌梅肉 枳实 犀角(镑) 黄芩(各半两) 甘草(二钱半) 生地黄(一两)
每服五钱水一盏半煎至八分去滓服按此方阳证宜之
王肯堂:太阳病经过三天,已经发汗,或者用了催吐、泻下、温针等治疗方法,但病情仍然没有解除的,这叫做“坏病”。此时不能固定使用桂枝汤来治疗。应当观察病人的脉象和证候,了解医生犯了什么错误(误治),然后根据具体的证候进行治疗。所谓“逆”,是指不应当发汗而发了汗,不应当泻下而用了泻下,或者汗法、下法使用过度,这些都不符合治疗原则,所以称为“逆”。“随证治之”的意思,就像后文所说:“发汗后病未解”、“发汗或泻下后病仍不解”,分别用某某汤主治之类的方法。 “随证治之”这句话含义灵活且广泛。王冰、韩祗和等医家将坏病单独作为一种证型,并用羊肉汤来主治,这是错误的。
原本的太阳病没有解除,转入少阳经,出现胁下硬满、干呕、不能进食、往来寒热等症状,如果还没有经过催吐或泻下,脉象沉紧的,给予小柴胡汤治疗。如果因为使用了催吐、泻下、发汗、温针等方法,导致病人出现谵语(说胡话),说明柴胡证已经消失,这属于坏病。要了解医生犯了什么错误,按照相应的法则进行治疗。
赵献可:张仲景在论述中所说的坏病,是指太阳病误用发汗、催吐、泻下之后,出现的虚烦、结胸、痞气、吐后内烦、腹胀满等证候。这正是指桂枝汤证不再适用,以及小柴胡汤证消失的情况。哪里是指像《活人书》所说的“异气”导致的坏病呢?张仲景又说:“更感异气变为他病”,这就是所谓二气、三气杂合为病的说法。因为这些病名尚未确定,不同于四种温病,所以称之为变病。而且关于四经温病,张仲景认为冬天感受寒邪,到春天发作成为温病;温病未愈,再次感受邪气,变为温疟、风温、温毒、温疫病,这些都没有被称为“坏”,所以称之为变证。一个叫坏病,一个叫变证,名称自然是不同的。由此可见,“异气”不属于坏病,这一点是很清楚的。假如温疟果真是坏病,那么张仲景就不会说“小柴胡汤证罢”了。请仔细思考。
是斋方:伤寒的阴证和阳证分辨不清,或者用药错误,导致患者病情危重、濒临死亡,发病七天以后都可以服用此方。传说服用此方一千次不会失手一次。用法:取优质人参一两,去掉芦头,薄片切好,用水一大升(约1000毫升),在银器或石器中煎煮至一盏(约200毫升),用新水冷却药液,使其变冷,一次性服完。反应是:汗液不从其他部位流出,只在鼻梁尖端涓涓渗出如水珠,这就是药效的体现,非常奇妙。苏韬光说:侍郎方丈曾经用这个方子救了几十个人。王使君在清流县任职时,车申屠行父的儿子产后患时疫,十多天已经成了坏病,偶然询问此事,发现他只服用人参一味药,于是病就好了。当时并不知道有这个方子,只是偶然暗合罢了。
海藏(张元素):阳证在大汗、大下之后,阳气外亡,阴血内耗,上则津液脱失,下则体液枯竭,津液两伤,应该用羊肉汤来补益。何况阴证患者,难道可以不温补吗?这与伤寒太阳证出现振颤摇动而用真武汤治疗的例子类似,都是阳病至此阶段仍需温补,况且内部的阴寒证候,怎么能不补呢?
韩祗和:产后失血导致血虚的人,适宜用羊肉汤。伤寒因发汗、泻下太过导致亡阳、失血的,如果只用救逆汤,疗效必然迟缓。使用羊肉汤,疗效神速。病患面色虽然看似有阳热表现,那是客热(假热)。上焦、中焦、下焦的阴气已经旺盛。如果调理得当,使下焦产生阳气,那么上焦的阳气就能下降,丹田之气也能有所归宿。气有高下之分,病有远近之别,证有表里之异,治有轻重之度,各适其宜才能痊愈。所以病已八九日,因发汗、泻下太过,脉象沉细无力,多蜷缩双脚卧倒,厌恶听到人声,皮肤起鸡皮疙瘩,时常战栗像疟疾一样,适宜用羊肉汤主治。
羊肉汤方:当归、白芍药、牡蛎(赤石脂,各一两)、生姜(二两)、桂枝(七钱半)、龙骨(通赤色,半两)、黑附子(炮制,去皮去脐,四钱)。以上药材捣成粗末。每次服用一两药末,配羊肉四两,葱白五寸,生姜心同切碎烂煮。用水五升,熬煮减少一半,过滤去渣,分三次服用。按:此方适用于阴证。
鳖甲散:治疗伤寒八九天不好,各种药物无效,名为坏伤寒。鳖甲(醋炙后研末)、升麻、前胡、乌梅肉、枳实、犀角(镑片)、黄芩(各半两)、甘草(二钱半)、生地黄(一两)。每次服用五钱,加水一盏半,煎至八分,去渣服用。按:此方适用于阳证。
Wang Kentang: If the Taiyang disease (disease of the Taiyang channel) has persisted for three days, and although sweating therapy (diaphoresis), emesis, purgation, or warm needle therapy have been applied, the condition remains unresolved, this is termed a "ruined disease" (bad illness resulting from mismanagement). At this stage, Guizhi Tang (Cinnamon Twig Decoction) cannot be fixedly prescribed. One must observe the pulse and symptoms to determine what error (mis-treatment) was committed, and then treat according to the specific presentation. The term "ni" (adverse/rebellious) refers to situations where sweating was induced when it should not have been, or purgation was used when it should not have been, or when sweating and purgation were excessive; these actions do not accord with therapeutic principles, hence they are called "adverse." "Treating according to the syndrome" means, as stated later: "If the disease does not resolve after sweating," or "if the disease persists after sweating or purgation," one prescribes specific decoctions accordingly. The phrase "treating according to the syndrome" is flexible in meaning and broad in scope. Wang Bing, Han Zhihe, and other physicians erroneously treated "ruined disease" as a distinct syndrome and prescribed Roushang Tang (Mutton Soup) as the primary treatment.
If the original Taiyang disease does not resolve and transitions into Shaoyang disease (disease of the Shaoyang channel), presenting with hardness and fullness below the costal margin, dry retching, inability to eat, and alternating chills and fever, if no emesis or purgation has yet been performed and the pulse is deep and tight, Xiaochaihu Tang (Minor Bupleurum Decoction) should be administered. However, if due to the use of emesis, purgation, sweating, or warm needles, the patient develops delirium (speaking nonsense), indicating that the Chaihu syndrome has ceased, this constitutes a ruined disease. One must ascertain the nature of the adverse treatment and manage it according to appropriate principles.
Zhao Xianke: In Zhang Zhongjing's discussions, "ruined disease" refers to conditions such as deficiency-heat irritability, chest binding (jie xiong), epigastric fullness (pi qi), internal irritability after vomiting, and abdominal distension following the erroneous application of sweating, emesis, or purgation in Taiyang disease. This precisely refers to the inapplicability of Guizhi Tang and the cessation of Xiaochaihu Tang syndromes. It certainly does not refer to illnesses caused by "heterogeneous pathogens" (yi qi) as described in *Huoren Shu* (The Man Who Saves Lives). Zhang Zhongjing also stated, "Contracting heterogeneous pathogens leads to transformation into other diseases," which refers to the mixing of two or three pathogens causing illness. Since these conditions lack definitive names, they differ from the four types of warm diseases (wen bing) and are thus termed "transformed diseases." Regarding the four channels of warm diseases, Zhang Zhongjing posited that winter cold injury manifests as warm disease in spring; if the warm disease persists and re-exposure occurs, it transforms into warm malaria, wind-warmth, warm toxin, or warm epidemic. These were never termed "ruined," but rather "transformed syndromes." Thus, "ruined disease" and "transformed syndrome" are distinct nomenclatures. It is clear that heterogeneous pathogens do not constitute ruined diseases. Consider this carefully: if warm malaria were truly a ruined disease, Zhang Zhongjing would not have mentioned the cessation of the Xiaochaihu Tang syndrome. Ponder upon this.
Shizhai Formula: When the yin and yang patterns of Shanghan (Cold Damage) are indistinguishable, or medicinal errors cause the patient to become critically ill and near death, this formula may be administered even seven days after onset. Legend holds that its efficacy is nearly infallible. Preparation: Take high-quality Ren Shen (Ginseng Radix et Rhizoma), 1 liang, remove the rhizome (lu), slice thinly. Boil in 1 sheng (approx. 1000 ml) of water in a silver or ceramic vessel until reduced to 1 zhan (approx. 200 ml). Cool the decoction using fresh water until cold. Administer in a single dose. The expected reaction is perspiration emerging only from the tip of the nasal bridge, dripping like water droplets, which indicates the drug's effect. This is miraculous. Su Taoguang reported: The Abbot of the Vice Minister's residence once saved dozens of people using this formula. When Envoy Wang served in Qingliu County, the son of Che Shentu Xingfu suffered from an epidemic postpartum for over ten days, already constituting a ruined disease. Upon inquiry, he was found to be taking only Ren Shen, after which he recovered. At that time, the existence of this specific formula was unknown; it was merely a coincidental alignment.
Haizang (Zhang Yuansu): After excessive sweating and purgation in yang-pattern diseases, yang collapses externally and blood depletes internally. Upper depletion involves body fluids (jin ye), while lower depletion involves essences. With both fluids and essences exhausted, Roushang Tang (Mutton Soup) should be used to tonify. How much more so for yin-pattern diseases, which require warming and tonification? This parallels the case of Taiyang disease presenting with tremors and shaking, treated with Zhenwu Tang (True Warrior Decoction); even in such advanced yang-pathology, warming is necessary. How much more essential is tonification for internal yin-cold patterns?
Han Zhihe: Patients with blood deficiency due to postpartum hemorrhage are suitable for Roushang Tang (Mutton Soup). In Shanghan, if excessive sweating and purgation lead to collapse of yang and loss of blood, using only Jiuni Tang (Rescue the Perdition Decoction) will yield slow results. Roushang Tang acts swiftly. Although the patient's complexion may appear to show yang heat, this is likely "guest heat" (false heat). Yin qi in the upper, middle, and lower jiao (burners) is abundant. If the lower jiao is regulated to generate yang, the yang qi of the upper jiao can descend, and the dantian (lower abdomen) will find its proper residence. Qi has levels of ascent and descent; diseases have distances of origin and manifestation; syndromes have interior-exterior distinctions; treatments have degrees of severity. Healing occurs when each aspect is appropriately addressed. Therefore, if the disease has persisted for eight or nine days, and excessive sweating/purgation has resulted in deep, thin, and weak pulses, with the patient curling up, lying down, aversion to sound, skin goosebumps, and chills resembling malaria, Roushang Tang (Mutton Soup) is indicated.
Roushang Tang (Mutton Soup) Formula: Dang Gui (Angelicae Sinensis Radix), Bai Shao Yao (Paeoniae Radix Alba), Mu Li (Ostreae Concha) [Note: Text mentions Chi Shi Zhi here contextually or as variant, but standard Mu Li is Oyster Shell], Sheng Jiang (Zingiberis Rhizoma Recens), Gui Zhi (Cinnamomi Ramulus), Long Gu (Fossilia Ossis Mastii), Hei Fu Zi (Aconiti Lateralis Radix Praeparata - Black Prepared Aconite Root). Dosages: Dang Gui, Bai Shao Yao, Mu Li (Chi Shi Zhi/Red Ochre per text note, usually Mu Li in standard texts, adhering to text: Chi Shi Zhi) 1 liang each; Sheng Jiang 2 liang; Gui Zhi 7 qian 5 fen; Long Gu (reddish throughout) 0.5 liang; Hei Fu Zi (prepared, skin and core removed) 4 qian. Grind herbs into coarse powder. For each dose, take 1 liang of herb powder, 4 liang of mutton, 5 cun of scallion white, and ginger heart. Chop finely. Boil in 5 sheng of water until reduced by half. Filter and remove dregs. Divide into three doses. Note: This formula is suitable for yin-patterns.
Biejia San (Soft-shelled Turtle Powder): Treats Shanghan persisting for eight or nine days without improvement, unresponsive to various medications, termed "ruined Shanghan." Ingredients: Bie Jia (Testudinis Carapax et Plastrum, vinegar-fried and powdered), Sheng Ma (Cimicifugae Rhizoma), Qian Hu (Peucedani Radix), Wu Mei (Mume Fructus), Zhi Shi (Aurantii Fructus Immaturus), Xi Jiao (Rhinocerotis Cornu - *Note: Use substitutes in modern practice*), Huang Qin (Scutellariae Radix), Gan Cao (Glycyrrhizae Radix et Rhizoma), Sheng Di Huang (Rehmanniae Radix). Dosages: Bie Jia, Sheng Ma, Qian Hu, Wu Mei, Zhi Shi, Xi Jiao, Huang Qin: 0.5 liang each; Gan Cao: 2 qian 5 fen; Sheng Di Huang: 1 liang. For each dose, take 5 qian of powder, add 1.5 zhan of water, boil until reduced to 0.8 zhan. Filter and administer. Note: This formula is suitable for yang-patterns.