治伤寒阴阳二毒相伏，危恶形证。
舶上硫黄 水银 太阴石 太阳石 元精石（各一两） 硝石（半两）
上件药末，先用无油铫子，以文武火炒，下诸药末，令匀如灰色，研细如粉面，生姜自
然汁浸
，桂汤下。慎不得于屋底炒。
海藏云∶此丸为阴阳二毒相伏匿，故用脑子、牛黄、蜜水调下。若明见只是阴证，别无
伏阳
，不宜用此下之。若有伏阳，当以仲景翕奄沉脉法责之。在许学士破阴丹条下。叔和云
∶短脉阴中有伏阳。
治伤寒服冷药过度，心腹胀满，四肢逆冷，昏沉不识人，变为阴毒恶证。
肉桂（三分） 赤芍药（一两） 陈皮（一两） 前胡（一两） 附子（一两，炮） 当归（一两）
白
两）
上粗末，每服五钱，水一中盏，枣三枚，煎至六分，去滓，不拘时候，稍热服。
上此一条，以其先是阳证，为服凉药过多，变为阴毒，故内有前胡一味。知少阳不止，
乃用药之过也，与泻心汤加附子相似。
治阴毒伤寒，面青，手足逆冷，心腹气胀，脉沉细。
硫黄（半两，研） 木香（半两） 荜澄茄（半两） 附子（半两，制） 干姜（一分） 干蝎（
半两，炒） 吴茱萸（半两，汤洗，炒）
上细末，酒煮糊为丸桐子大。每服三十丸，生姜汤下，频服，复以热酒一盏投之，以衣
盖取汗。
治疗伤寒病中阴阳二毒相互潜伏，出现危重恶劣的证候。
舶上硫黄、水银、太阴石、太阳石、元精石（各一两）、硝石（半两）。
将上述药物研成细末，先用无油的锅，用文火和武火交替炒制，加入各种药末，炒至均匀呈灰色，再研磨得细如粉面，用生姜自然汁浸泡制成丸剂，用肉桂汤送服。严禁在阴暗潮湿处炒制。
海藏（王好古）说：此丸用于阴阳二毒相互潜伏隐匿的情况，所以用冰片、牛黄，用蜜水调服。如果明确看见只是阴证，没有潜伏的阳邪，不适宜用此方攻下。如果有潜伏的阳邪，应当依据张仲景的“翕奄沉”脉法来诊察。详见许学士《破阴丹》条目下。叔和（王叔和）说：短脉是阴中有潜伏的阳邪。
治疗伤寒服用寒凉药物过度，导致心腹胀满，四肢逆冷，神志昏沉不识人，转变为阴毒恶证。
肉桂（三分）、赤芍药（一两）、陈皮（一两）、前胡（一两）、附子（一两，炮制）、当归（一两）、白术（一两）。
将上述药物捣成粗末，每次服用五钱，用水一中盏，大枣三枚，煎煮至六分，去渣，不拘时候，稍热时服用。
以上这一条，因为其起初是阳证，因服用凉药过多，转变为阴毒，所以方中含有前胡一味药。知道少阳病未愈，是用药的错误，这与泻心汤加附子的情况相似。
治疗阴毒伤寒，面色青黑，手足逆冷，心腹部气胀，脉象沉细。
硫黄（半两，研磨）、木香（半两）、荜澄茄（半两）、附子（半两，炮制）、干姜（一分）、全蝎（半两，炒制）、吴茱萸（半两，汤洗后炒制）。
将上述药物研成细末，用酒煮糊制作成梧桐子大小的丸剂。每次服用三十丸，用生姜汤送服，频繁服用，随后再饮一盏热酒，用被子覆盖以取汗。
Treats the condition of Yin and Yang poisons in cold damage (Shanghan) mutually lurking, presenting with critical and malignant symptoms.
Bo Shang Shihuang (Shipborne Sulfur), Shuiyin (Mercury), Taiyinshi (Taiyin Stone), Taiyangshi (Taiyang Stone), Yuanjingshi (Yuanjing Stone) (each 1 liang), Xiaoshi (Niter) (0.5 liang).
Grind the above medicines into fine powder. First, use a non-oily pot, stir-fry using alternating mild and strong heat, add all the powdered medicines, stir-fry until uniform and gray in color, then grind finely like flour. Soak with fresh ginger juice to form pills. Take with Rougui Tang (Cinnamon Twig Decoction). Strictly avoid stir-frying in dark or damp places.
Haizang (Wang Haogu) stated: This pill is used for the mutual lurking and hiding of Yin and Yang poisons; therefore, Naobzi (Borneolum Syntheticum) and Niuhuang (Calculus Bovis) are used, taken with honey water. If it is clearly seen as merely a Yin syndrome without any lurking Yang pathogen, it is not appropriate to use this formula for purging. If there is a lurking Yang pathogen, one should apply Zhang Zhongjing's pulse method of "Xi Yan Chen" (fluttering and sinking pulse) to investigate. Refer to Xu Xueshi's entry on Poyin Dan (Breaking Yin Pill). Shuhe (Wang Shuhe) stated: A short pulse indicates Yang pathogen lurking within Yin.
Treats cold damage where excessive intake of cold-natured medicines has led to abdominal distension and fullness, cold limbs, mental confusion and inability to recognize people, transforming into a malignant Yin poison syndrome.
Rougui (Cortex Cinnamomi) (3 fen), Chishao Yao (Radix Paeoniae Rubra) (1 liang), Chenpi (Pericarpium Citri Reticulatae) (1 liang), Qianhu (Radix Peucedani) (1 liang), Fuzi (Radix Aconiti Lateralis Preparata) (1 liang, processed), Dang Gui (Radix Angelicae Sinensis) (1 liang), Baizhu (Rhizoma Atractylodis Macrocephalae) (1 liang).
Pound the above ingredients into coarse powder. Each dose is 5 qian. Use 1 zhen of water and 3 jujubes. Decoct until reduced to 6/10 volume. Strain the dregs. Take at any time, slightly warm.
Regarding this entry, since it initially was a Yang syndrome that transformed into Yin poison due to excessive intake of cooling medicines, the formula contains Qianhu (Radix Peucedani). Knowing that Shaoyang disease persists indicates an error in medication, similar to the situation with Xiexin Tang (Gallbladder-Draining Decoction) plus Fuzi.
Treats Yin poison cold damage, characterized by bluish complexion, cold extremities, abdominal qi distension, and a deep, thin pulse.
Shihuang (Sulfur) (0.5 liang, ground), Muxiang (Radix Aucklandiae) (0.5 liang), Bichengqie (Fructus Tetradii) (0.5 liang), Fuzi (Radix Aconiti Lateralis Preparata) (0.5 liang, processed), Ganjiang (Rhizoma Zingiberis Secati) (1 fen), Ganzhe (Scorpio) (0.5 liang, stir-fried), Wuzhuyu (Fructus Evodiae) (0.5 liang, washed with hot water and stir-fried).
Grind the above into fine powder. Boil with wine to make a paste, forming pills the size of tung tree seeds. Each dose is 30 pills, taken with Shengjiang Tang (Fresh Ginger Decoction). Take frequently. Subsequently, drink one cup of hot wine and cover with blankets to induce sweating.