凡心烦心喘，妄语见鬼，以不落水猪心血和冰片，丸如芡实大，每服一丸，以紫草煎酒
下。少刻下瘀备，神清，痘即红活透出。此医所不能治者，百发百中，神应非常。
又方∶升麻一味，先煎浓汤去渣，用胭脂十余张，于汤内揉出红汁，加明雄黄末钱余，
即以胭脂绵蘸汤于疮上试之，胭脂红花膏所染，故能活血散毒也。如疮不起发，试之亦可，
神效非常。
自胸以上，自脐以下俱有，中间一截全无者，名两头痘。此血气不能贯通于上下，而腰
脐之间，恐为寒毒凝滞也。若不急治，七日之后，必变灰白之症矣。见点时，急用生 、当
归、赤芍、桔梗、防风、浓朴、续断、白芷、山楂、木通，入黄豆三十粒，煎服之后，中间
有痘，乃可无虞。
头面遍身俱无空地，状若蛇皮，故以是名。必干枯不能作浆，至十二三日而死。昔予孙
女出痘如此，发热之时，寒战切牙，口气臭甚，常如食物。余曰∶此恶候也。急与解毒，用
解毒汤，日进三四服，及痘出密如蚕种，颗粒不明，乃用前胡、川芎、丹皮、栀子（炒黑）、
紫草茸、人中黄、连翘、牛蒡、黄芩、红花，连进数服，乃分颗粒。其后加生 、白芷，去
人中黄、紫草、黄芩、红花等药，其水渐升。乃用参归鹿茸汤加丁桂、白芷、白芍、次加白
术，其浆乃足。浆起之候，竟似蛇皮，落痂之际，或片连皮而去，遍身如蛇蜕壳，手足指甲
无一未落，毛发悉皆脱换，其症果蛇皮也。善以治之，亦竟安全，可见不治之症，亦勿弃而
不治也。但症遇恶烈，药必猛攻，而迁延观望，岂能救乎。
凡是出现心烦、心气喘促，胡言乱语甚至看见鬼魂症状的，用未落水的小猪心血配合冰片，制成如芡实大小的药丸，每次服用一丸，用紫草煎酒送服。不久后瘀血排出，神志清醒，痘疹就会变得红润鲜活并透发出来。这是普通医生无法治疗的病症，但此法百发百中，疗效神奇非凡。
另一个方子：只用升麻一味药，先煎煮成浓汤去渣，取十余张胭脂在汤中揉出红汁，加入雄黄末约一钱，然后用沾有胭脂的棉蘸取药汤涂抹在疮面上试之（若染上胭脂红花膏的颜色，说明能活血散毒）。如果痘疮不起发，试用此法也可，疗效非常神奇。
从胸部以上到肚脐以下都有痘疹，唯独中间一段完全没有的，称为“两头痘”。这是因为气血不能贯通上下，腰部与肚脐之间恐怕被寒毒凝滞所致。如果不紧急治疗，七天之后，必然转变为灰白色的死症。在痘疹刚出现时，急忙使用生地黄、当归、赤芍、桔梗、防风、厚朴、续断、白芷、山楂、木通，加入三十粒黄豆，煎服后，中间部位长出痘疹，才可以没有危险。
头面及全身都没有空地，形状像蛇皮一样，所以以此命名。痘疹必定干枯不能化脓结浆，到了十二三日就会死亡。过去我的孙女出痘就是这样，发热的时候，寒战咬牙，口气极臭，常常像食物腐烂的味道。我说：这是恶候。急忙给予解毒治疗，使用解毒汤，每天进服三四次，等到痘疹出得密集如蚕种，颗粒不分明时，才使用前胡、川芎、丹皮、栀子（炒黑）、紫草茸、人中黄、连翘、牛蒡子、黄芩、红花，连续服用几剂，痘疹才分颗粒分明。其后加上生地黄、白芷，去掉人中黄、紫草、黄芩、红花等药，痘液逐渐上升。接着使用参归鹿茸汤加丁香、肉桂、白芷、白芍，随后再加白术，痘浆才充足。痘浆起发的阶段，竟然像蛇皮一样，结痂脱落的时候，有的成片连着皮一起脱落，全身像蛇蜕壳一样，手足指甲无一不脱落，毛发全部脱换，这病症果然是蛇皮痘。善于治疗的话，最终也能保全性命，可见即使是不可治之症，也不要放弃不治疗。但是病情遇到恶劣猛烈时，用药必须猛攻，而拖延观望，怎么能救得回来呢？
In cases where there is mental restlessness, panting of the heart, delirious speech, and hallucinations of seeing ghosts, use the heart blood of a piglet that has not touched water mixed with Borneolum Syntheticum (Bingpian), formed into pills the size of a Chinese chestnut. Take one pill per dose, administered with wine decocted from Arnebiae Radix seu Lithospermi Radix (Zicao). Shortly after, stasis will be discharged, consciousness will clear, and the smallpox lesions will become red, vibrant, and erupt. This condition is beyond the treatment capability of ordinary physicians, yet this method is infallible and extraordinarily effective.
Another prescription: Use only Cimicifugae Rhizoma (Shengma) as a single herb, first decoct it into a concentrated soup, remove the dregs, take more than ten sheets of Carthami Flos (Honghua/Zhiyancai) and rub them in the soup to extract red juice, add approximately one qian of realgar powder (Xionghuang), then dip cotton stained with carmine-red paste into the soup to test on the sores (if it stains like carmine-red flower paste, it indicates the ability to invigorate blood and dissipate toxicity). If the sores do not rise or erupt, testing with this method is also viable, yielding extraordinary effects.
When lesions are present from above the chest to below the navel, but completely absent in the middle section, it is named "Two-Ended Smallpox" (Liangtou Dou). This occurs because Qi and Blood cannot circulate between the upper and lower parts, suggesting stagnation by cold-toxin in the region between the waist and navel. If not treated urgently, after seven days, it will inevitably transform into a grayish-white fatal syndrome. At the stage when spots first appear, urgently administer Rehmanniae Radix Preparata (Sheng Dihuang), Angelicae Sinensis Radix (Danggui), Paeoniae Radix Rubra (Chishao), Platycodonis Radix (Jiegeng), Saposhnikoviae Radix (Fangfeng), Magnoliae Officinalis Cortex (N Houpo), Dipsaci Radix (Xuduan), Angelicae Dahuricae Radix (Baizhi), Crataegi Fructus (Shanzha), and Akebiae Caulis (Mutong), along with thirty soybeans. After decoction and ingestion, if lesions emerge in the middle section, there will be no cause for concern.
When the head, face, and entire body have no empty space, resembling snake skin, hence the name. The lesions will inevitably become dry and fail to form pus, leading to death by the twelfth or thirteenth day. Previously, my granddaughter contracted smallpox in this manner. During fever, she experienced severe chills and teeth grinding, with extremely foul breath smelling like rotting food. I stated: "This is an ominous sign." Urgently administer detoxification using Jiedu Tang (Detoxifying Decoction), three to four doses daily. When the lesions became dense like silkworm eggs and indistinct in granularity, switch to Peucedani Radix (Qianhu), Chuanxiong Rhizoma (Chuanxiong), Moutan Cortex (Danpi), Gardeniae Fructus (Zhizi, stir-fried black), Arnebiae Radix (Zicao Rong), Hominis Placenta (Renzhonghuang), Forsythiae Fructus (Lianqiao), Arctii Fructus (Niubangzi), Scutellariae Radix (Huangqin), and Carthami Flos (Honghua). Continue for several doses until the lesions distinguish their granules. Subsequently, add Rehmanniae Radix Preparata (Sheng Dihuang) and Angelicae Dahuricae Radix (Baizhi), removing Hominis Placenta (Renzhonghuang), Arnebiae Radix (Zicao), Scutellariae Radix (Huangqin), and Carthami Flos (Honghua), allowing the fluid to gradually rise. Then use Shen Gui Lurong Tang (Ginseng, Angelica, and Deer Antler Decoction) added with Caryophylli Flos (Dingxiang), Cinnamomi Cortex (Rougui), Angelicae Dahuricae Radix (Baizhi), and Paeoniae Radix Alba (Baishao), followed by adding Atractodis Macrocephalae Rhizoma (Baizhu), at which point the pus becomes sufficient. During the pus-raising phase, the appearance resembled snake skin. Upon scab shedding, some pieces came off with the skin, leaving the whole body looking like shed snake skin; fingernails and toenails all fell off, and hair was completely replaced. The condition was indeed Snake-Skin Smallpox. With skilled treatment, safety could ultimately be achieved, demonstrating that even incurable conditions should not be abandoned without treatment. However, when the condition is malignant and fierce, medicines must attack vigorously; procrastination and hesitation cannot save the patient.