〔王氏（大纶）痘痧心法〕二卷 存
〔秦氏（昌迈）痘疹折衷〕二卷 存
〔殷氏（仲春）痧疹心法〕一卷 存
秀水县志曰。殷仲春。字方叔。自号东皋子。工岐黄。隐居教授。茆屋葭墙。不蔽风雨。生平落落寡合。惟
与禾中高士高松声姚士舜王淑民释智舷相过从。载酒问奇。刻烛分韵。所着有医藏目录。栖老堂集。
〔李氏（中梓）痘科点〕未见
按〔朱氏（巽）痘科键〕二卷 存
朱凤台序曰。治人之病。莫难于婴儿。婴儿之病。莫险于痘证。余少时出痘。几为医者所误。长而闻父母言。
每竦然自危。而并为众婴儿危。以故留心斯证。苟有良方。无不采辑。忽获秘传上下卷。如得拱璧照乘。用是搜
讨诠次。穷岁月之力。而后授之梓。客曰。其名键。何也。曰。键者。户钥也。户非钥无以开。是书之于痘。犹
钥之于户耳。客曰。出子之言。使婴儿得免于庸医之手。子之功孰大焉。曰。医者得是书。而究心焉。以保婴儿
于无事。医者之功。与婴儿之命也。于余何者。犹之今天下 安。海晏河清。如人一元宁泰。四肢和畅。此天子
之社也。医国者敢尸其劳哉。靖江
朱凤台慎人父漫题于退思堂。
按桐溪池田柔行曰。是书宛陵朱巽述家秘之口诀。与古人之要论。而所辑录。原无题名。靖江朱凤台者。撰
次刊行。名曰痘科键。若因期施治篇。金镜赋。节制赋。指南赋。自始热至落痂余六篇。自虚变实。至治虚弱二
法论十则。并见于金镜录。麻疹篇。概见于保赤全书。其他间有古人之论。若自发热。至落痂余毒口六则。满天
秋。救苦丹。热见愁。千里马。赛春雷。一丸春等方论。俱见于丹台玉案。考玉案。系崇祯中孙文胤所着。虽不
知与是书先后奈何。据朱巽言而查之。是书所引。春沂师桂农子吴东园之说。玉案亦载之。不记出典。是书有家
大人曰之语。玉案亦载其说。无家大人曰字。要之是书立论。多有古贤未发之论。明辨详委。宋元以来痘科之书。
无虑数十家。未见出于是书之右者。则是岂剽袭旧说。以为己所着者耶。于是断为成于朱巽之手者。唯原本颇多
错文。是凤台从其稿本。未经校勘者也。
〔汪氏（继昌）痘科秘诀〕未见
婺源县志曰。汪继昌。字伯期。大畈人。先世多业岐黄。昌始奋学能文。试不遇。寻复专医术。挂瓢黄山白
岳。精阴阳司天之说。调五行生克。黜奇霸不用。活人无算。时称国手。尤于治痘有异传。常语人曰。痘科无死
证。其不治者医之咎也。所着有痘科秘袂行世。性谦让。喜施予。济人缓急无德色。有长浓风。
〔李氏（延 ）痘疹全书〕未见
按上见于曝书亭高士李君塔铭。
〔蔡氏（继周）保嗣痘疹灵应仙书〕二卷 存
自序曰。医药二字。古有金匮玉板。岐黄问答。灵枢难经脉诀。何其详备明正焉。周切思痘疹一门。名曰小
儿科。口不能道寒热之情。心不能辨甘苦之味。席天幕地。忽遭成人虎变之时。生死攸关之日。令父母手足无措。
延一医家。或有矢口乱谈。曰补则补。曰泻则泻。惟命是从。孰知补泻之间。命若悬丝。宾主昏黑。不知医之理。
妙契穹苍。若人也有蹈白刃之勇。辞爵禄之廉。能中庸之德者。然后可行。其用法与诸科不同。但知参 能补。
早则闭毒于内。邪正两争。顷刻杀人。又知巴豆大黄能泻。元气已弱。伶仃之际。再授摧残。即能杀人。周不擅
补不擅泻。执中正之理。以告天下。欲求天下不信者。吾不信也。周自庚戌援例。家难频仍。横逆叠至。致误领
虎观。横经之教诲也。久期射策金门。午马岁月。苟得浮生三日之暇。竟写尘芜数万之言。任从取舍。周始祖讳
楷字子式。嘉定二年。以椒房懿亲如海康。七世祖讳道泰。至顺二年。举贤良方正。宗五世祖讳胃字用岩。知余
千。宗祖奉祀万安桥。从兄时宜号玄谷。计擒徐海。逐汪五峰毛海峰。侄文龙年十八。用三折利刀。赶退胡平。
冲犁围击。忘食者三书夜。急在成功。阵亡米碎。周父讳山。号童川。母李氏。俱可事神明。周五岁时。命置义
庄田记。然组宗遣下山场。约止八万。余将讼雷电公明之下。恢复故物。警戒山邻鱼肉之过。节年蒙一二名卿面
命着书。忽起此念。谨勒痘疹仙书上下二卷。咸成一部。躬具四方。博济将来。孟子云。知命者。不立乎岩墙之
下。此刻愿人就利避害耳。又思文不及斑马。才不及韩范。敢乞人序跋。以累名公之心目乎。俟二三年内。将经
义书旨。大小方脉。伤寒金镜录。次第完就。聊答天地父母之心也。或蹈山林。或桴湖海。或爻翠竹苍松。栽花
灌园。惕然长悟。尽然长笑。不知所云。甬东季愚子蔡继周。
〔亡名氏痘疹秘要〕一卷 存
陈楚瑜序曰。治痘方书。古今传授。毋虑百家。求其剀
切中程者。恒不易得。先君子历宦于虔。得遇泰和萧子。与之为莫逆。此君久以治痘。驰名海内。知光君子留心
此道。暇日乃出其师所辑痘证一编相授。先君子得之。大加叹异。自后凡遇遘斯证者。以之疗治。多获奇验。顾
以未经剞劂。是致人皆罕见。迨迁宜阳司理。常拟刻于署中。未几以善病罢归。逾年遂尔见背。此书几至湮没。
甲子闱后。予既落魄。闲居无事。偶检遗笥幸编帙尚存。痛念先人素怀所钟。不忍听其散逸。爰收蠹鱼之余。订
其讹舛。更题曰痘疹秘要。付之梓人。俾广其传。以承先志。故于工竣之日。而述其概如此。天启乙卯孟秋。南
海陈楚瑜谨识。
〔吴氏（国翰）痘疹保婴汇粹鉴衡集〕二卷 存
序因曰。余生多艰。而子息为尤。历十有数胎。止得三男一女。其他惊搐死者有之。而死于痘者。最为酷烈。
因忿极。窃思古来诸杂证。皆有方药可治。岂痘遂无真传耶。乃遍求诸家。参互考订。其发端指归。缕缕焉。凶
险疑难死证。若皆可目稽手授。诚可藉为活人方寸资矣。然学人往往悉举成书。口诵心维。历岁月而淹熟者。无
虑数辈。及用药而先后倒施。温凉误用。虚实舛观。致有庸医杀人之咎。读书之效。茫如捕风。何也。岂书之误
人哉。要以繁冗者不芟截。当参驳者未能简汰故尔。翰甚苦之。因出臆见。广搜名公所说。刊其繁芜。汇而成编。
其议之精详者因虽尽。而大意则无不该。方之确当者未必备。而投剂或可无误。虽挂一漏万。理所必有。但其条
陈者。约而明。简而该。观采甚便。情知蠡测之识。必见笑于方家。而愚性鄙固。自为千虑一得。或可为学人津
梁云。因述俚识以识。
〔江氏（旭奇）痘经〕（或作痘疹大全）三卷 存
〔亡名氏痘疹直指方〕一卷 存
〔痘疹心书〕一卷 存
〔程氏（嘉祥）家传经验痧麻痘疹秘集〕五卷 存
自序略曰。余先大人号心宇亦号岐滨。幼肄儒。蹶而习医。先大父东谷公曰。嗟嗟。学何必为儒。诚有裨于
世。何非儒行乎。乃出其所秘授于诸明公者。以示先大人。大人学而思之。夜以继日。觉于于然若有所得。每施
于世。无不应手。嗣而访天下之明医。如方龙山方嗣塘何肖充姚少琼汪炉峰黄万山夏少江诸君。与上下其议论。
博极群书。学问益准。先大人勤于笔。每治则载一方。着一案。其间有得之书者。有得之心。而发书之覆者。有
得之友者。有得之己。而济友之所不及者。一列于策。余幼笃于儒。惜父之功无继。未表于世。遂弃而攻医。先
大人因授秘旨。余益潜心医学。存则与之共视。究其证之颠末。故则凭其抉治之精微。随所施效如桴鼓。益信射
于百步之外。至者力也。中者巧也。善乎孟夫子之言夫。然有而秘之与无同。于济世之心。毋乃大谬不然乎。况
济在一方者德小。济在天下者德大。济在一时者功有限。济在世世者功无穷。若是非付之剞劂氏。曷足以遂。故
尽其秘旨。凡研之简编。而验之临症者。悉记之于书。以公于世。俾人人一展卷。而昭如日星。即按方而治危险
之证。无错乱舛误。苏亿万人于一人。谓非仁者赠人以言乎。而先大人洎予济人利物之心。庶几发抒其万一云。
〔吕氏（献策）痘疹幼幼心书〕十七卷 存
自序曰。余自束发时。从事举子业。未晓医也。顷先严抱足疾。不离床榻者数年。日随诸医侍药。因究心于
岐黄诸
书。遂与医习。先是有妇人调经一书。盖怆心于无嗣者而刊也。言简意该。人用之效若谷响。至婴儿一科。存之
黄帝时。未有言着。故医家皆以哑科为最难事。夫固谓杂证难。而不知痘疹尤难也。夫痘疹结局。在一十四日之
内。自发热以至收靥。一日一小变化。三日一大变化。生死悬于呼吸。情势迫于危急。为儿父母者。见其倏忽间。
置儿于烈火寒水之中。仓卒靡藉。听信庸医。颠倒错乱。夭人性命。可畏也哉。余常聚麻痘书数种。参考研寻。
历十余年。纂汇始成。大约按证治方。挨日顺序。始终本末。条理不乱。论皆常语。不为钩深。方多根据古。不敢
立异。犹恐开卷之余。昧者莫解。又将药性炮制分疏首编。使人一卷。了然心目。可不问医而自为焉。然尤致详
于形色动静。寒热虚实之辨。总以升发解毒为主。温补之中。必兼升解。升解之后。急须温补。要在于燕越歧路
处着力耳。嗣后余子若女。遇时行痘疹。照证对治。咸繇此脱厄。余沾沾喜曰。吾得以幼吾幼矣。然犹以不及人
为恨也。值里中亲友。佥命广其传。余以艰于梓为辞。会苞之席之两弟慨然助成。因得启其笥藏。而付诸梨人曰。
人有饥者饲之食。人有寒者纩之衣。人有劳者。休息而安逸之。婴儿有欲无言。倘有抱痘而吟呻。染疹而困厄者。
医谁药之。而谁疗之。是编成。人得于是取筏焉。庶幼吾幼。以及人之幼也。故名曰幼幼心书。崇祯八年夏杪。
古平原吕献策匡时题于静笃轩。
〔吴氏（元溟）痘科切要〕一卷 存
自序曰。余父道川公精岐黄。凡男妇大小抱疾者。投剂辄效。余则勤恳 哗间。弗克治也。年弱冠而母病。
病且剧。余仓皇侍汤药。母因语父曰。茕茕孤子。既令业儒。不若兼令业医。以广其学。父慨然为之耳提口授。
余亦因之详求博考。究脉探原。遂为理路稍通焉。至于痘疹一科。尤兢兢三致其意。然未知切要也。万历丁亥冬。
时行出痘。几遍乡邑。父日阅二三十人。且命余偕往。曰。痘书虽多。未得要领。惟临机应变为无穷。切要在能
认证。非亲视莫可指传也。盖痘分顺逆险三种。其间顺险各半。逆者十亦二三。有顺证误成险证。误成逆证者居
多。因而据证。剖示其表里虚实。按岁气。分部位。察形观色。酌以寒热温凉。而治之之理。犹如舟人把舵。不
可乱推。乱则覆。又以庖人笼之法譬之。酵未发。而起火早。则面烧死。酵已发。而起火迟。则面塌坍。故要在
讨酵发火之际。不可违误时刻也。盖痘于五六日前。宜疏散解毒。药用清凉。五六日后。宜抱里助浆。药用温补。
其切要在凉补转换之间。勿违时刻。良于是矣。夫顺证误人。或不致大害。若险证一误。则变态多端。莫可解救。
慎之慎之。余故于兹编。名之曰痘科切要。昔余父得传于燕湖丁氏。再传于余。余复加以日历已验之见。汇成一
集。不敢私秘。读发之梓。就正高明云。祟祯丁丑岁孟冬月。光禄寺署丞古歙吴元溟澄甫氏书。
〔费氏（启泰）救偏琐言〕十卷 存
自序曰。尝思道无名象。虚寂无为。威而即应。妙用无穷。不可得而思议。不独大道为然。医之为道。上关
运气。下切 。而寄生命。虽曰小道。能不灵变乎哉。至痘之一证。有常有变。吉凶反复。生死尤限于日期。
一不洞彻。而失圆转。可生之痘。陷于不起。讵以泥文执象。克任斯道乎。论痘自放点以至落痂。赖气制化其毒。
而终始其功。以故前执此。而按期定法。据证立方。虽有不齐。大都以扶元
为重。治毒为轻。防危虑患。咸以虚脱为虞。常道其宜尔也。抑知痘犯元枭烈毒。犹夫火宅。不第制化有所不受。
连气亦为毒瓦斯。血亦为毒血矣。视变为常。而反倒置。有不速其毙耳。况时有变迁。痘多变局。试阅今之败于虚
者。几上残花。毙于毒者。大林秋叶也。虚与毒之辨。似是者居多。此非成见所能别。亦非聪明所能定也。能以
四大机关。一一深求而参合之。痘之不等于前。今之毙类于毒。可坐而照矣。令痘悉毙于虚。其于充实之体。当
不登于幽录。乃有痘未及浆。而便有是惨者。何也。其于薄弱之躯。自不留于尘世。乃有浆不烦助。而得有以称
庆者。又何也。衡其毒迫于虚。何得以虚。而忽其毒。毒之所在。命悬顷刻。亦奚暇论小而襁褓。大而早婚。与
值病后哉。挈其当胜之急。得靖杀身之毒。斯见大智。余盖历来治验。笔难广记。信不诬也。妙在参其毒耳。如
篇中所载。种种恶形恶色。与夫症状之猖狂。神情之扰乱。其与气虚者。固已远隔参商。更异夫内蕴不拔之毒。
见症若虚。深潜燎原之火。见症若寒。较之暴厉而发扬者。险恶尤为莫测。恒多并形也。而色独异。并色也。而
【王氏（大纶）痘痧心法】二卷，现存。
【秦氏（昌迈）痘疹折衷】二卷，现存。
【殷氏（仲春）痧疹心法】一卷，现存。
秀水县志记载：殷仲春，字方叔，自号东皋子。精通岐黄之术，隐居并从事教学。茅草屋、芦苇墙，无法遮蔽风雨。生平孤高不合群，只与禾中高士高松声、姚士舜、王淑民以及僧人智舷交往。他们载着酒去请教新奇之事，刻烛限韵作诗。所著书籍有《医藏目录》、《栖老堂集》。
【李氏（中梓）痘科点】未见。
按语：【朱氏（巽）痘科键】二卷，现存。
朱凤台在序言中说：治疗人的疾病，没有比婴儿更难的了。婴儿的疾病中，没有比痘证更危险的。我年少时出痘，差点被医生误治。长大后听父母讲述此事，常常感到惊恐危惧，并为众多婴儿感到担忧。因此留心研究这一病症，如果有良方，无不搜集整理。忽然获得秘传的上下两卷书，如同得到拱璧和照乘之珠一样珍贵。于是搜求探讨、编排次序，耗尽一年的精力，然后刻印出版。客人问：这本书名为“键”，为什么呢？回答说：键就是钥匙。门没有钥匙就无法打开，这本书对于痘证的治疗，就像钥匙对于门一样。客人说：您的言论，使婴儿得以避免庸医之手，您的功劳还有谁比得上呢？回答说：医生得到这本书，并用心钻研，从而保护婴儿免受病痛，这是医生的功劳，关乎婴儿的生命，与我个人有什么关系呢？这就好比天下安宁，海清河晏，如同一个人元气宁静泰和，四肢通畅舒畅，这是天子的社稷啊。治理国家的人敢独揽其功劳吗？靖江朱凤台慎人父在退思堂漫题。
按语：桐溪池田柔行说：这本书是宛陵朱巽陈述家传秘诀，结合古人的重要论述，而所辑录的内容，原本没有题名。靖江朱凤台编纂刊行，命名为《痘科键》。其中如《因期施治篇》、《金镜赋》、《节制赋》、《指南赋》，从初热到落痂余毒共六篇；从虚变实到治疗虚弱二法论十则，都见于《金镜录》；麻疹篇，概见于《保赤全书》。其他间或有古人的论述，如从发热到落痂余毒口六则，《满天秋》、《救苦丹》、《热见愁》、《千里马》、《赛春雷》、《一丸春》等方论，都见于《丹台玉案》。考证《丹台玉案》，是崇祯年间孙文胤所著。虽然不知道它与这本书的先后顺序如何，但据朱巽所言查证，这本书引用的春沂师桂农子吴东园的说法，《玉案》中也记载了，只是不记出处。这本书中有“家大人曰”的话语，《玉案》中也载有其说，但没有“家大人曰”这四个字。总之，这本书立论，多有古代贤人未曾发表的见解，明辨详细委曲。宋元以来痘科的书籍，不少于数十家，未见有超过这本书的。那么这难道是剽窃旧说，作为自己所著的吗？于是断定此书成于朱巽之手。只是原本有很多错别字，这是因为朱凤台从其稿本刊刻，未经过校勘的缘故。
【汪氏（继昌）痘科秘诀】未见。
婺源县志记载：汪继昌，字伯期，大畈人。祖先多从事医学。汪继昌开始发奋学习并能写文章，科举考试不中，不久又专攻医术。悬挂瓢葫芦于黄山白岳之间，精通阴阳司天之说，调理五行生克关系，摒弃奇险霸道之法不用，救活的人无数，当时被称为国手。尤其对治疗痘证有独特传承。常对人说：痘科没有死证，治不好的是医生的过错。所著有《痘科秘袂》流传于世。性格谦让，喜欢施舍，救济他人的急难而没有得意之色。患有浓风病（一种皮肤病）。
【李氏（延 ）痘疹全书】未见。
按语：上文见于曝书亭高士李君塔铭。
【蔡氏（继周）保嗣痘疹灵应仙书】二卷，现存。
自序说：医药二字，古代有《金匮》、《玉板》，岐黄问答，《灵枢》、《难经》、脉诀，何其详细完备、明白正确啊。周密思考痘疹这一门类，名叫小儿科，孩子口不能说出寒热的感觉，心不能辨别甘苦的味道，面对天地，忽然遭遇成人虎变之时，生死攸关之日，让父母手足无措。请一位医生来，或许有人信口乱谈，说要补就补，说要泻就泻，完全听从命令，谁知道补泻之间，生命像悬在丝线上一样危险。主客昏黑，不懂医理，妙合天道。如果人有蹈白刃的勇气，辞爵禄的廉洁，能守中庸之德的人，然后才可以行医。其用法与其他科室不同。只知道人参能补，用早了就会闭毒于内，邪正两争，顷刻杀人。又知道巴豆、大黄能泻，元气已经虚弱，伶仃之际，再给予摧残，就能杀人。我不擅长补，也不擅长泻，执守中正的道理，告知天下。想要寻求天下人不相信的，我是不信的。我从庚戌年通过捐纳得官，家中灾难频繁，横逆接连到来，导致耽误了在虎观阁接受教诲的机会。长久期望在金门射策，午马岁月。如果能得到浮生三日的闲暇，竟然写下数万字的尘芜之言。任由人们取舍。我的始祖名楷，字子式，嘉定二年，以椒房懿亲的身份前往海康。七世祖名道泰，至顺二年，举荐为贤良方正。宗五世祖名胃，字用岩，知余千县。宗祖奉祀万安桥。从兄时宜号玄谷，计擒徐海，驱逐汪五峰、毛海峰。侄儿文龙十八岁，用三折利刀，赶退胡平，冲犁围击，废寝忘食三天三夜，急于成功，阵亡米碎。父亲名山，号童川，母亲李氏，都可以侍奉神明。我五岁时，父亲命设立义庄田记，然而组织宗族派遣下山场，大约只有八万。我将向雷电公明申诉，恢复故物，警戒山邻鱼肉百姓的过错。历年蒙受一二位名卿当面命令著书，忽然兴起这个念头，谨编撰《痘疹仙书》上下二卷，合成一部，亲自具备四方，博济将来。孟子说：知命的人，不站在陡峭的墙壁之下。此刻希望人们趋利避害。又想到文采不及斑马，才华不及韩范，敢乞求别人作序跋，以累及名公的心目吗？等待两三年内，将经义书旨、大小方脉、伤寒、《金镜录》，次第完成，聊以报答天地父母之心。或者投身山林，或者泛舟湖海，或者爻翠竹苍松，栽花灌园，惕然长悟，尽然长笑，不知道说了什么。甬东季愚子蔡继周。
【亡名氏痘疹秘要】一卷，现存。
陈楚瑜在序言中说：治疗痘方的书籍，古今传授，不少于百家。寻求其中切实中肯的，常常不容易得到。先父在虔州做官时，遇到泰和萧子，与他成为莫逆之交。这位先生长期以治疗痘证驰名海内外。知道光君子留心此道，闲暇时便拿出他老师所辑录的痘证一篇传授给我。先父得到后，大为叹异。从此凡是遇到患此症的人，用它来治疗，多获得奇妙验证。只是因为未经刻印，导致人们都很少见到。等到迁任宜阳司理，常打算在署中刻印，不久因病罢官回家。过了一年便去世。这本书几乎湮没。甲子科考之后，我已经落魄，闲居无事，偶然检查遗留的箱子，幸好书册还在。痛念先人素怀所钟，不忍听其散失，于是收集被虫蛀剩下的部分，订正其中的讹误，改题为《痘疹秘要》，交给刻工，使其广泛传播，以继承先人的遗志。所以在工程完工之日，叙述大概如此。天启乙卯年孟秋，南海陈楚瑜谨识。
【吴氏（国翰）痘疹保婴汇粹鉴衡集】二卷，现存。
序言说：我一生多艰难，而子息更是如此。经历十几胎，只得到三个儿子一个女儿。其他的有的因惊搐而死，而死于痘证的，最为残酷猛烈。因此愤怒至极，私下想自古以来各种杂证，都有方药可治，难道痘证就没有真传吗？于是遍求各家，参互考订。其发端指归，条理清晰。凶险疑难死证，似乎都可以亲眼目睹、亲手传授，确实可以借此作为救人的方寸依据。然而学医的人往往全部列举成书，口诵心维，经过多年淹熟者，不少于几辈。等到用药时却先后倒施，温凉误用，虚实错看，导致有庸医杀人的罪过。读书的效果，茫如捕风，为什么呢？难道是书的错误吗？主要是繁冗的内容没有删减，应当参驳的内容未能简汰的缘故。我很为此苦恼，于是提出自己的见解，广泛搜集名公所说，刊除繁芜，汇编成编。议论精详的，虽然不一定穷尽，但大意无不涵盖。方剂确当的，未必完备，但投药或许不会出错。虽然挂一漏万，是理所必然的，但其条陈的内容，简约而明了，简单而完备，观察采集非常方便。明知是蠡测之识，必会被方家嘲笑，但我本性鄙陋固执，自认为千虑一得，或许可以作为学人的津梁。于是陈述浅识以记录。
【江氏（旭奇）痘经】（或作《痘疹大全》）三卷，现存。
【亡名氏痘疹直指方】一卷，现存。
【痘疹心书】一卷，现存。
【程氏（嘉祥）家传经验痧麻痘疹秘集】五卷，现存。
自序略说：我的先父号心宇，也号岐滨。幼年研习儒家经典，失意后改习医学。先祖父东谷公说：唉，学习何必一定要做儒生？如果确实对世道有益，什么不是儒者的行为呢？于是把他所秘密传授给各位明公的知识，展示给先父。先父学习并思考它，夜以继日，觉得悠然自得，好像有所收获。每次应用于世间，没有不随手奏效的。随后拜访天下的名医，如方龙山、方嗣塘、何肖充、姚少琼、汪炉峰、黄万山、夏少江诸位先生，与他们上下议论，博览群书，学问更加精准。先父勤于笔耕，每次治疗都记载一方，写一案。其中有从书中得到的，有从心中领悟而发现书本不足的，有从朋友那里得到的，有从自己实践中得到而弥补朋友不足的。一一列于简策。我幼年笃信儒家，可惜父亲的功业无人继承，未能在世上表露，于是放弃儒学而攻习医学。先父因此传授秘旨，我更加潜心医学。活着时与他共同审视，探究病症的始末；去世后凭借他抉治的精微。随所施用，效如桴鼓。更加相信射箭在百步之外，到达是因为力量，命中是因为技巧。孟夫子说得好啊。然而有而不秘同于无，对于济世之心，岂不是大大谬误吗？况且济世在一方，德行小；济世在天下，德行大；济世在一时，功绩有限；济世在世世，功绩无穷。如果不交给刻工，怎么足以实现呢？所以倾尽秘旨，凡是研读简编而验证于临床的，都记录在书中，公开于世。使人人展开书卷，就昭如日月星辰，即使按照方子治疗危险的病症，也不会错乱失误。让亿万人由一人拯救，这难道不是仁者赠人以言吗？而先父以及我济人利物的心意，或许能抒发万一吧。
【吕氏（献策）痘疹幼幼心书】十七卷，现存。
自序说：我从束发时起，从事举子业，不懂医学。近来先父患足疾，不离床榻数年。我每天跟随各位医生侍奉汤药，因此用心研究岐黄诸书，于是与医学结缘。先前有一本《调经》书，大概是针对无子嗣者而刊行的。言辞简要，意思完备，人们使用它，效果如山谷回响。至于婴儿这一科，存于黄帝时代，没有言语著作。所以医家都以哑科为最难的事。本来就说杂证难，却不知道痘疹更难。痘疹的结局，在十四天之内。从发热到收靥，一天一小变化，三天一大变化，生死悬于呼吸，情势迫于危急。作为孩子的父母，看到孩子在倏忽之间，被置于烈火寒水之中，仓促无依靠，听信庸医，颠倒错乱，夭折人性命，可怕啊。我常聚集麻痘书数种，参考研寻，历经十余年，纂汇才完成。大致按照病症治疗方剂，挨日顺序，始终本末，条理不乱。论述都是平常话语，不追求深奥。方剂多根据古人，不敢标新立异。还担心开卷之余，愚昧者不能理解，又将药性炮制分疏放在首编，使人一卷在手，了然于心，可以不问医生而自己操作。然而特别详细于形色动静、寒热虚实的辨别。总以升发解毒为主，温补之中，必须兼有升解。升解之后，急须温补。关键在于在燕越歧路处着力。此后我的子女，遇到时行痘疹，照证对治，都由此脱厄。我沾沾自喜地说：我可以爱护我的幼小了。然而仍然以不及人为恨。正值乡里亲友，一致命我广泛传播。我以难以刻印为借口推辞。恰逢苞之、席之两位弟弟慷慨助成，于是得以开启箱柜，交给刻工说：人有饥饿的，给他食物；人有寒冷的，给他棉衣；人有劳苦的，让他休息安逸。婴儿有欲望却无法言语，如果有抱着痘疹呻吟、染上疹子困厄的，医生谁来医治？谁来治疗？这部书编成，人们得以从中取筏，或许可以爱护我的幼小，进而爱护别人的幼小。所以命名为《幼幼心书》。崇祯八年夏末，古平原吕献策匡时在静笃轩题写。
【吴氏（元溟）痘科切要】一卷，现存。
自序说：我的父亲道川公精通岐黄之术。凡男女老少抱病者，投药辄效。我却勤恳于喧哗之间，无暇治理。二十岁时母亲生病，病情严重。我仓皇侍奉汤药。母亲因而对父亲说：孤独的儿子，既然让他从事儒业，不如兼让他从事医业，以广其学。父亲慨然为之耳提面授。我也因此详细寻求、广泛考察，探究脉象、探求本源，于是思路稍微通达。至于痘疹这一科，尤其兢兢业业，三次致意。然而不知道切要之处。万历丁亥年冬天，时行出痘，几乎遍及乡邑。父亲每天阅读二三十人，并且命我一同前往，说：痘书虽然多，但未得要领，只有临机应变为无穷。切要在能够认证，非亲眼观看不可指传。大概痘分顺、逆、险三种。其中顺证和险证各占一半，逆证十分之二三。有顺证误成险证、误成逆证的情况居多。因而根据证候，剖示其表里虚实，按照岁气，分部位，察形观色，斟酌以寒热温凉，而治疗的道理，犹如船夫把舵，不可乱推，乱推则会翻船。又以厨师蒸笼的方法比喻：酵未发，而起火早，则面烧死；酵已发，而起火迟，则面塌坍。所以要在讨取酵发火之际，不可违误时刻。大概痘在五六日前，宜疏散解毒，药用清凉；五六日后，宜抱里助浆，药用温补。其切要在凉补转换之间，勿违时刻，良在于此。顺证误人，或不致大害，若险证一误，则变态多端，莫可解救。慎之又慎。所以我在这部书中，命名为《痘科切要》。昔日我父亲得传于燕湖丁氏，再传于我，我又加上日历已验的见解，汇集成集，不敢私秘，读发刻印，向高明请教。祟祯丁丑年孟冬月，光禄寺署丞古歙吴元溟澄甫氏书写。
【费氏（启泰）救偏琐言】十卷，现存。
自序说：曾经思考道无名象，虚寂无为，威而即应，妙用无穷，不可得而思议。不独大道如此，医之为道，上关运气，下切...而寄生命，虽曰小道，能不灵变乎哉。至于痘之一证，有常有变，吉凶反复，生死尤限于日期。一不洞彻，而失圆转，可生之痘，陷于不起。岂以泥文执象，克任斯道乎。论痘自放点以至落痂，赖气制化其毒，而终始其功。以故前执此，而按期定法，据证立方，虽有不齐，大都以扶元为重，治毒为轻，防危虑患，咸以虚脱为虞。常道其宜尔也。抑知痘犯元枭烈毒，犹夫火宅，不第制化有所不受，连气亦为毒瓦斯，血亦为毒血矣。视变为常，而反倒置，有不速其毙耳。况时有变迁，痘多变局。试阅今之败于虚者，几上残花，毙于毒者，大林秋叶也。虚与毒之辨，似是者居多。此非成见所能别，亦非聪明所能定也。能以四大机关，一一深求而参合之，痘之不等于前，今之毙类于毒，可坐而照矣。令痘悉毙于虚，其于充实之体，当不登于幽录，乃有痘未及浆，而便有是惨者，何也。其于薄弱之躯，自不留于尘世，乃有浆不烦助，而得有以称庆者，又何也。衡其毒迫于虚，何得以虚，而忽其毒。毒之所在，命悬顷刻，亦奚暇论小而襁褓，大而早婚，与值病后哉。挈其当胜之急，得靖杀身之毒，斯见大智。余盖历来治验，笔难广记，信不诬也。妙在参其毒耳。如篇中所载，种种恶形恶色，与夫症状之猖狂，神情之扰乱，其与气虚者，固已远隔参商。更异夫内蕴不拔之毒，见症若虚，深潜燎原之火，见症若寒，较之暴厉而发扬者，险恶尤为莫测。恒多并形也。而色独异。并色也。而
[Wang's (Dalun) Xinfa for Smallpox and Measles] Two volumes, extant.
[Qin's (Changmai) Zhezhong on Smallpox and Measles] Two volumes, extant.
[Yin's (Zhongchun) Xinfa on Measles] One volume, extant.
The Gazetteer of Xiushui County records: Yin Zhongchun, courtesy name Fangshu, self-styled Donggaozi. He was proficient in Qihuang (the Yellow Emperor and Shennong, representing traditional Chinese medicine), lived in seclusion, and engaged in teaching. His thatched hut with reed walls could not shelter him from wind and rain. He was aloof and incompatible with the world, associating only with scholars such as Gao Songsheng, Yao Shishun, Wang Shumin, and the monk Zhi Xian in Heshang. They would bring wine to inquire about novel matters and compose poetry by dividing rhyme schemes under a carved candle. His authored works include *Yicang Mulü* (Catalogue of Medical Treasures) and *Qilaotang Ji* (Collected Works of Qilao Hall).
[Li's (Zhongzi) Dianke on Smallpox] Not seen.
Note: [Zhu's (Xun) Kejian on Smallpox] Two volumes, extant.
Zhu Fengtai wrote in the preface: Treating human diseases is most difficult with infants. Among infant diseases, none is more perilous than smallpox. In my youth, I suffered from smallpox and nearly fell victim to medical error. As I grew up and heard my parents recount the incident, I would feel startled and fearful, worrying for all infants. Thus, I paid close attention to this condition. Whenever I encountered good prescriptions, I collected them without exception. Suddenly, I obtained a secret transmission in two volumes, as precious as an arch-bi (a legendary jade) or a light-shining pearl. I searched, discussed, and organized it, exhausting a year's effort, before having it printed. A guest asked: Why is the book named "Kejian" (Key)? I replied: Kejian means key. A door cannot be opened without a key; this book regarding smallpox is like a key to a door. The guest said: Your words allow infants to avoid the hands of quacks. Who can surpass your merit? I replied: If doctors obtain this book and study it diligently, they can protect infants from harm. This is the doctor's merit, concerning the lives of infants. What does it have to do with me personally? It is like the peace of the world, clear seas and rivers, akin to a person whose Yuan Qi (Original Qi) is tranquil and harmonious, with limbs flowing smoothly. This belongs to the Son of Heaven's statecraft. How dare those who govern the nation claim the credit alone? Zhu Fengtai, father of Shenren, inscribed casually at Tuisi Hall in Jingjiang.
Note: Chiba Yūkō of Tongxi stated: This book was compiled by Zhu Xun of Wanling, presenting family secrets and important discussions from ancients. The original compilation had no title. Zhu Fengtai of Jingjiang edited and published it, naming it *Kejian on Smallpox*. Chapters such as "Treatment According to Stages," "Golden Mirror Ode," "Restraint Ode," and "Compass Guide Ode," covering six sections from initial heat to scab falling and residual toxins, along with ten treatises on transforming deficiency into excess and treating weakness, are all found in *Jingjin Lu*. The measles chapter is generally found in *Baochi Quanshu*. Other occasional ancient theories, such as six treatises from fever to residual toxins, and formulas like *Mantianqiu*, *Jiuku Dan*, *Rejianchou*, *Qianlima*, *Saichunlei*, and *Yiwanchun*, are all found in *Dantai Yu'an*. Research shows *Dantai Yu'an* was authored by Sun Wenyin during the Chongzhen reign. Although the chronological order between this book and *Dantai Yu'an* is unknown, according to Zhu Xun's statements, the theory of Wu Dongyuan (styled Guinong, teacher Chunyi) cited in this book is also recorded in *Yu'an*, though the source is not noted. This book contains phrases like "My Father said," which appear in *Yu'an* but without the specific phrase. In summary, this book's arguments often contain insights not previously expressed by ancient sages, clearly distinguished and detailed. Since the Song and Yuan dynasties, dozens of smallpox books have been written, none exceeding this one. Could it be plagiarized old theories passed off as original? Thus, it is concluded that this book was authored by Zhu Xun. However, the original text contained many errors because Zhu Fengtai printed it from a draft manuscript without collation.
[Wang's (Jichang) Mijue on Smallpox] Not seen.
The Gazetteer of Wuyuan County records: Wang Jichang, courtesy name Boqi, from Daban. His ancestors were mostly in medicine. Wang began to strive in learning and writing, but failed the imperial examinations. He then devoted himself to medicine, hanging his gourd at Mount Huangshan and Baiyue. He mastered the theories of Yin-Yang and Si Tian (Six Qi ruling the year), regulated the generation and restriction of the Five Elements, rejected bizarre and domineering methods, and saved countless people, earning the title "National Master." He had special transmissions for treating smallpox. He often told others: There are no fatal cases in smallpox treatment; failures are the doctor's fault. His work *Mijue on Smallpox* was circulated. He was humble, generous, helped others in emergencies without showing pride, and suffered from a skin disease called "Nongfeng."
[Li's (Yan...) Quanshu on Smallpox and Measles] Not seen.
Note: The above is mentioned in the tomb inscription of Scholar Li Ta of Boshuting Pavilion.
[Cai's (Jizhou) Baosi Lingying Xianshu on Smallpox and Measles] Two volumes, extant.
Autobiographical Preface: The terms "medicine" and "pharmacy" have ancient roots in the *Jinkui*, *Yuban*, dialogues of Qibo and Huangdi, *Lingshu*, *Nanjing*, and pulse manuals. How detailed and correct they are! Upon careful reflection, pediatrics, specifically smallpox and measles, is called "Pediatrics." Infants cannot speak of cold or heat, nor distinguish sweet or bitter. Facing heaven and earth, they suddenly undergo the transformation of childhood, a critical moment of life and death, leaving parents helpless. Calling a doctor might result in random talk: "Tonify if needed, purge if needed." Following orders blindly, one does not know that between tonification and purging, life hangs by a thread. Masters and disciples are confused, ignorant of medical principles, failing to align with the Dao. Only those with the courage to walk on white blades, the integrity to refuse titles and wealth, and the virtue of the Golden Mean can practice medicine. Its usage differs from other specialties. Knowing only that Ginseng tonifies, using it too early closes toxins inside, causing evil and righteous Qi to clash, killing instantly. Knowing only that Croton seed and Rhubarb purge, using them when Yuan Qi is weak and fragile causes further destruction, leading to death. I am neither skilled in tonifying nor purging. I adhere to the principle of centrality and justice to inform the world. I believe no one will doubt this. Since the Gengxu year, I entered office through purchase, facing frequent family disasters and adversity, delaying my education at the Tiger Gate Academy. I longed to pass the exams at the Golden Gate. Given three days of leisure in this floating life, I wrote tens of thousands of words of dust-like text, leaving it to others' discretion. My ancestor, Kai, styled Zishi, went to Haikang in the 2nd year of Jiading as a relative of the Empress. My seventh-generation ancestor, Daotai, was recommended as "Worthy, Upright, Honest, and Square" in the 2nd year of Zhishun. My fifth-generation ancestor, Wei, styled Yongyan, served as Magistrate of Yuqian. Ancestor Wu served at Wan'an Bridge. My cousin, Shi Yi, styled Xuangu, plotted to capture Xu Hai and drove away Wang Wufeng and Mao Haifeng. My nephew, Wenlong, at eighteen, used a three-edged sword to repel Hu Ping, charging and plowing the siege, forgetting food for three days and nights, eager for success, dying in battle. My father, Shan, styled Tongchuan, and mother, Lady Li, could serve the spirits. At five years old, my father ordered the establishment of a charity estate field record. Organizing clan lands amounted to only eighty thousand. I intended to appeal to the Thunder God for justice to recover property and warn neighbors against bullying. Over the years, honored ministers commanded me to write books. Suddenly, this idea arose. I carefully compiled *Xianshu on Smallpox and Measles* in two volumes, completing one set, ready for four directions, to benefit the future. Mencius said: "He who knows destiny does not stand under a precipitous wall." This carving hopes people seek profit and avoid harm. Thinking my literary talent is inferior to Ban Ma, and my ability inferior to Han Fu and Fan Zhongyan, I dare ask for prefaces and postscripts to burden the minds of famous scholars. Within two to three years, I will complete commentaries on classics, internal and external medicine, Shanghan, and *Jingjin Lu*, to repay the hearts of Heaven, Earth, and Parents. Whether entering mountains, boating on lakes, observing bamboo and pines, planting flowers, or watering gardens, I will awaken with awe, laugh fully, and not know what I say. Ji Yuzi Cai Jizhou from Yongdong.
[Anonymous Mi Yao on Smallpox and Measles] One volume, extant.
Preface by Chen Chuyu: Books on smallpox prescriptions, transmitted from ancient to modern times, number over a hundred families. Finding one that is precise and effective is hard. My late father served in Qianzhou, where he met Xiao Zi from Taihe, becoming close friends. This gentleman had long been famous nationwide for treating smallpox. Knowing that Guang Junzi was interested in this field, he gave me a manuscript of smallpox cases compiled by his teacher during his leisure. My father greatly admired it. Since then, whenever encountering such cases, using it yielded miraculous results. However, lacking printing, few people saw it. When transferred to Yiyang as a judicial officer, he planned to print it there, but soon retired due to illness. A year later, he passed away. This book was nearly lost. After the Jiazi examination, I was destitute and idle. Checking a leftover chest, I luckily found the pages intact. Pained by my father's deep attachment, I could not bear to let it scatter. I gathered the remaining parts after insect damage, corrected errors, retitled it *Mi Yao on Smallpox and Measles*, and gave it to printers to spread its transmission and fulfill my father's will. Thus, I narrate this upon completion. Early Autumn of Yimao Year, Tianqi, Chen Chuyu of Nanhai respectfully recorded.
[Wu's (Guohan) Huicui Jianheng Ji on Smallpox and Measles for Infant Protection] Two volumes, extant.
Preface: My life has been full of hardships, especially regarding offspring. After more than ten pregnancies, I only got three sons and one daughter. Others died of convulsions, but those dying of smallpox were the cruelest. Out of extreme anger, I thought: Ancient miscellaneous diseases all have treatments. Does smallpox lack true transmission? I sought various schools, cross-referenced and verified. The origins and goals became clear. Dangerous, difficult, and fatal cases seemed observable and teachable, truly serving as a guide for saving lives. However, students often memorize existing books, reciting and thinking for years until familiar. Yet when prescribing, they reverse the order, misuse warm/cool properties, and misjudge deficiency/excess, leading to the blame of quack doctors killing patients. The effect of reading is like catching wind. Why? Is it the book's fault? Mainly because redundant content was not cut, and questionable content was not simplified. I suffered greatly from this. Thus, I presented my views, widely collected statements from masters, removed redundancy, and compiled a collection. Detailed discussions, though not exhaustive, cover the main ideas. Accurate prescriptions, though not complete, ensure correct administration. Though listing one may miss ten thousand, it is inevitable. But the items listed are concise and clear, simple and comprehensive, convenient for observation and selection. Knowing my limited knowledge will be laughed at by experts, yet being stubborn, I consider it a gain from a thousand deliberations, perhaps serving as a bridge for learners. Thus, I record my humble thoughts.
[Jiang's (Xuqi) Jing on Smallpox] (Or *Daquan on Smallpox and Measles*) Three volumes, extant.
[Anonymous Zhizhi Fang on Smallpox and Measles] One volume, extant.
*Xinshu on Smallpox and Measles* One volume, extant.
[Cheng's (Jiaxiang) Family Transmission Jingyan Collection on Measles, Chickenpox, and Smallpox] Five volumes, extant.
Brief Autobiographical Preface: My late father, styled Xinyu and also Qibin, studied Confucianism in his youth, failed, and then practiced medicine. My grandfather, Donggu Gong, said: Alas, why must learning be solely Confucian? If it benefits the world, is it not Confucian conduct? He showed my father secrets taught by various masters. My father studied and pondered day and night, feeling enlightened and gaining something. Every application worked instantly. Later, he visited famous doctors nationwide, such as Fang Longshan, Fang Sitang, He Xiaochong, Yao Shaoqiong, Wang Lufeng, Huang Wanshan, and Xia Shaojiang, discussing extensively, reading widely, and refining his knowledge. My father was diligent in writing, recording a prescription and case for each treatment. Some insights came from books, some from his mind revealing book deficiencies, some from friends, some from himself supplementing friends' lacks. All were listed in bamboo slips. I was devoted to Confucianism in my youth, regretting my father's unrecorded achievements. So I abandoned Confucianism for medicine. My father then passed down secret instructions. I devoted myself to medicine, studying with him while alive to understand disease processes, and relying on his subtle treatments after his death. Treatments were effective as drumsticks hitting targets. I believed Mencius's words: Shooting far requires strength; hitting the target requires skill. However, keeping secrets is like having none. For the sake of saving the world, isn't it wrong? Saving one area is small virtue; saving the world is great virtue. Saving one time is limited merit; saving generations is infinite merit. Without printing, how can this be achieved? So I revealed all secrets, recording everything studied and clinically verified, publishing it publicly. Let everyone open the scroll and see it clearly as sun and stars. Even treating dangerous cases according to prescriptions avoids confusion. Saving millions through one person—is this not benevolence giving words? May my father's and my intent to save people and benefit things be expressed.
[Lv's (Xiance) Youyou Xinshu on Smallpox and Measles for Infants] Seventeen volumes, extant.
Autobiographical Preface: From my youth, I engaged in civil service exams, unaware of medicine. Recently, my father suffered from foot disease, bedridden for years. I accompanied doctors daily, studying Qihuang texts, thus entering medicine. Previously, a book on regulating menstruation was published for those without heirs. It was concise and effective, echoing like a valley. Regarding infants, since the Yellow Emperor's time, no writings existed. Doctors considered "mute diseases" hardest. Indeed, miscellaneous diseases are hard, but smallpox is harder. Smallpox outcomes depend on fourteen days. From fever to scabbing, minor changes daily, major changes every three days. Life and death hang on breath, situations urgent. Parents see their children suddenly placed in fire and water, panicked, trusting quacks, causing chaos and death. Fearful! I gathered several smallpox books, researched for over ten years, and compiled this. Roughly, it follows symptoms and prescriptions, day-by-day sequence, clear logic. Discussions use common language, not seeking depth. Prescriptions follow ancients, daring not to innovate. Fearing readers might not understand, I placed drug properties and processing first, so one volume clarifies everything, allowing self-treatment without asking doctors. Especially detailed on distinguishing form, color, movement, temperature, and deficiency/excess. Generally focusing on ascending and detoxifying. In warming and tonifying, ascending and resolving must be included. After ascending and resolving, warming and tonifying are urgent. Key efforts lie at the crossroads. My children, encountering epidemic smallpox/measles, treated according to symptoms, escaped disaster. I rejoiced: I can care for my young. Yet I regretted not helping others. Relatives urged wide dissemination. I declined due to printing difficulties. Brothers Baozhi and Xizhi generously assisted. Opening my chest, I gave it to printers: Feed the hungry, clothe the cold, rest the weary. Infants cannot speak; if crying with smallpox or suffering measles, who treats them? This book serves as a raft. Perhaps caring for my young extends to others' young. Hence named *Youyou Xinshu*. Late Summer, 8th Year of Chongzhen, Lv Xiance Kuangshi of Guyuan inscribed at Jingdu Studio.
[Wu's (Yuanming) Qieyao on Smallpox] One volume, extant.
Autobiographical Preface: My father, Daochuan Gong, mastered Qihuang. Prescriptions for men, women, and children were always effective. I was busy with noise, unable to study. At twenty, my mother fell seriously ill. I anxiously served medicine. Mother told my father: "Our orphan son studies Confucianism; better he also studies medicine to broaden his learning." Father eagerly taught me orally and manually. I sought broadly, explored pulses and origins, gaining clarity. Smallpox required particular diligence. Yet I didn't grasp the essentials. Winter of Dinghai, Wanli era, smallpox epidemics swept the village. Father treated 20-30 people daily, taking me along, saying: "Smallpox books are many, but lack essentials. Adaptability is infinite. Essentials lie in accurate diagnosis, visible only by personal observation." Smallpox divides into Smooth, Adverse, and Dangerous types. Half smooth, half dangerous, 20-30% adverse. Many smooth cases become dangerous/adverse due to error. Based on symptoms, analyze exterior/interior, deficiency/excess, yearly Qi, locations, shape, color, and adjust warm/cool/hot/cold. Treatment is like a boatman steering;乱推 (pushing randomly) causes capsizing. Like a baker steaming dough: if fired too early before rising, bread burns; if fired too late after rising, bread collapses. Timing is crucial. Days 1-5: Disperse and detoxify with cool herbs. Days 6+: Support pulp formation with warm/tonic herbs. Essentials lie in switching between cool and warm without delay. Good indeed! Misjudging smooth cases causes little harm; misjudging dangerous cases leads to endless variations and no rescue. Be cautious! Hence named *Qieyao on Smallpox*. My father learned from Ding family of Yanhu, passed to me, I added verified observations, compiled this, dared not keep secret, printed for correction by experts. Early Winter, Dingchou Year, Chongzhen, Wu Yuanming Chengfu, Acting Director of Guanglu Temple, Gushi, wrote.
[Fei's (Qitai) Jiupian Suoyan] Ten volumes, extant.
Autobiographical Preface: I once thought Dao has no name or image, void and silent, non-action, responsive and miraculous, infinite, inconceivable. Not just Dao, but medicine: upper relates to Luck (Yunqi), lower concerns... and entrusts life. Though a minor art, can it not be agile? Smallpox has constants and variables, auspicious and ominous, life/death limited by dates. Lack of insight leads to loss of flexibility. Survivable smallpox becomes fatal. Can one rely on rigid texts? Discussing smallpox from eruption to scabbing relies on Qi to transform toxins and complete the process. Thus, earlier stages focus on supporting Yuan (Original Qi), treating toxins lightly, fearing collapse. This is the normal way. But knowing smallpox involves fierce toxins, like a burning house. Not only transformation fails, but Qi becomes toxic gas, Blood becomes toxic blood. Viewing change as constant reverses the order, hastening death. Times change, smallpox varies. Examining current failures: those failing from deficiency are like fading flowers; those from toxins are like autumn leaves. Distinguishing deficiency and toxin is tricky, mostly similar appearances. Not resolved by prejudice or cleverness. Deeply investigating four major mechanisms allows seeing that smallpox differs from past, and deaths resemble toxin cases. If all smallpox died from deficiency, robust bodies wouldn't enter underworld records. Yet some die before pulp formation—why? Weak bodies don't survive. Some need no help to pulp—why? Balancing toxin pressing on deficiency, how can one ignore toxin due to deficiency? Where toxin lies, life hangs in moments. No time to discuss infancy vs. early marriage or post-illness. Grasping urgency wins; calming killing toxin shows great wisdom. My clinical experiences are hard to record fully, but trust is not false. Essence lies in participating in toxin analysis. As recorded, various bad forms/colors, rampant symptoms, disturbed spirit differ greatly from Qi deficiency. More different from entrenched internal toxins. Symptoms seeming deficient hide prairie-fire flames; symptoms seeming cold are more unpredictable than violent outbreaks. Often co-existing. Colors uniquely differ. Co-existing colors...