丹溪先生曰∶痘风分气血虚实，虚则黄 生血之剂主之，佐以风药。实则白芍、黄芩为君，连翘、白芷、断续之颊
为佐。窃谓前症更当发，痘疮已出未出，已靥未靥，外邪所伤，内虚火动。若未出而搐搦，热毒内蕴也，紫草快 汤加
钩藤钩。已出红绽而搐搦，热毒作痛也，东垣消毒散加钩藤钩。贯脓而搐搦，血气虚也，参 四圣散加钩藤钩。若靥后
而搐搦，血气尤虚也，八珍汤加钩藤钩。或目 ，或直视者，风火相搏也，柴胡栀子散，或六味地黄丸加柴胡、山栀或
口角流涎者，木乘土也，五味异功散加升麻、柴胡、钩藤钩。或目赤眵泪者，肝血虚而生风也，四物汤加柴胡、钩藤钩。
或角弓反张者，水不生木也，六味地黄丸加柴胡、当归，随用补中益气汤，加天麻、钩藤钩，不可直用治风之药。盖风
药能燥血散气，必验其手足冷热温和三症，而用补泻调理之法，庶无误矣。如婴儿，当审乳母而治之。
一小儿痘疮将愈发搐，服牛黄清心丸，更口噤流涎，此脾胃复伤，肝木所侮，而涎不能归经耳，先用五味异功散加
钩藤钩，诸症顿减，次以五味异功散加柴胡而安。
一妇人出痘，因怒发搐，痘痕赤色，发躁作渴，面目皆赤，此汗多亡阳血脱而然也，先用当归补血汤二剂，躁渴顿
止；又用八珍、柴胡、牡丹皮、钩藤钩，热搐悉愈；又用八珍汤而痊。
一妇人痘疮将愈，因怒发搐口噤，头痛如裂，痘痕皎白，用补中益气汤加蔓荆子、钩藤钩顿愈。又因怒发搐，头晕
不食，先用补中益气汤加天麻，又六君、柴胡而安。
当归补血汤 治痘疮，血气亏损，发搐热渴喜饮，脉洪大而虚，重按如无者。（方见寒战切牙）
抱龙丸 治痘疮风热发搐，或痰甚者。
胆星（四两） 天竺黄（一两） 雄黄 朱砂（各五钱） 麝香（少许）
上为细末，用甘草一斤煎膏为丸，每一两作二十丸，用薄荷或灯心汤化下。
按∶前方肝经清热豁痰利气祛风之药，过剂则脾肺复伤而反甚。或更加胸腹作胀，食少作呕者，宜用人参白术散，
倍补中气。
造牛胆南星法 腊月，南星中大者为末，用黄牛胆汁拌匀，仍入胆壳内，以线扎口，悬挂当风处，阴干隔年
方可用，重制二三次者尤妙。
小柴胡汤（方见 症）
柴胡二连丸（方见前）
六味地黄丸（方见发热属阴阳）
四物汤（方见痘疮出迟）
十全大补汤（方见腹胀气促）
丹溪先生说：痘风（出痘后引发的惊风）需分辨气血的虚实。属虚证时，以生血剂为主，辅以祛风药。属实证时，以白芍、黄芩为君药，连翘、白芷、续断之根（原文“断续之颊”疑为“续断之根”或类似药材之误，此处依文意保留并标注）为佐药。
我认为上述病症更应当考虑发汗解表。无论痘疮已发出或未发出，已结痂或未结痂，若因外邪所伤、内火妄动而引发抽搐：
若痘未出而见抽搐，是热毒内蕴所致，用紫草快斑汤加钩藤钩；
若痘已出且红绽而见抽搐，是热毒作痛所致，用东垣消毒散加钩藤钩；
若痘灌浆期而见抽搐，是气血虚弱所致，用人参四圣散加钩藤钩；
若痘已结痂后而见抽搐，是气血更加虚弱所致，用八珍汤加钩藤钩。
若出现眼睛斜视或直视，是风火相搏所致，用柴胡栀子散，或六味地黄丸加柴胡、山栀；
若口角流涎，是肝木乘脾土所致，用五味异功散加升麻、柴胡、钩藤钩；
若目赤多眵流泪，是肝血虚而生风所致，用四物汤加柴胡、钩藤钩；
若出现角弓反张，是水不生木（肾水亏虚不能涵养肝木）所致，用六味地黄丸加柴胡、当归，随后酌情使用补中益气汤加天麻、钩藤钩，不可直接使用治风药。因为祛风药能燥血耗气，必须根据手足冷热温和这三项症状来验证，从而采用补泻调理的方法，这样才不至于出错。如果是婴儿患病，应当审查乳母的情况并一同治疗。
有一个小儿痘疮即将发作却出现抽搐，服用牛黄清心丸后，反而出现牙关紧闭、流涎，这是脾胃再次受伤，肝木侮脾，导致津液不能归经。先用五味异功散加钩藤钩，诸症顿时减轻，再用五味异功散加柴胡而痊愈。
有一个妇人出痘，因愤怒引发抽搐，痘痕呈赤色，烦躁口渴，面目皆红，这是汗出过多亡阳、血脱所致。先用当归补血汤两剂，烦躁口渴顿时停止；又用八珍汤、柴胡、牡丹皮、钩藤钩，发热抽搐全部治愈；最后用八珍汤而痊愈。
有一个妇人痘疮将愈，因愤怒引发抽搐、牙关紧闭，头痛如裂，痘痕颜色皎白，用补中益气汤加蔓荆子、钩藤钩，顿时痊愈。后来因愤怒再次引发抽搐，头晕不食，先用补中益气汤加天麻，后又用六君子汤、柴胡而安定。
当归补血汤：治疗痘疮，气血亏损，引发抽搐、发热口渴喜饮，脉象洪大而虚，重按如无者。（方剂见“寒战切牙”条下）
抱龙丸：治疗痘疮风热引发抽搐，或痰盛者。
配方：胆南星（四两）、天竺黄（一两）、雄黄、朱砂（各五钱）、麝香（少许）。
制法：以上研为细末，用甘草一斤煎膏为丸，每一两药粉作二十丸，用薄荷汤或灯心草汤化开服用。
按语：前面的方剂中，针对肝经清热、豁痰、利气、祛风的药物，如果过量使用，会再次损伤脾肺，使病情加重。如果出现胸腹胀满、食少呕吐等症状，宜用人参白术散，加倍补益中气。
造牛胆南星法：腊月时，选取大的南星研为粉末，用黄牛胆汁拌匀，仍装入胆壳内，用线扎口，悬挂在通风处，阴干一年后才可以服用，重复炮制二三次者尤为奇妙。
小柴胡汤（方剂见“疟疾”条下）
柴胡黄连丸（方剂见前文）
六味地黄丸（方剂见“发热属阴阳”条下）
四物汤（方剂见“痘疮出迟”条下）
十全大补汤（方剂见“腹胀气促”条下）
Mr. Danxi stated: "Dengfeng (convulsions occurring during the course of smallpox) should be differentiated by the deficiency or excess of Qi and Blood. In cases of deficiency, blood-nourishing formulas are primarily used, supplemented by wind-dispersing herbs. In cases of excess, White Peony Root (Baishao) and Scutellaria Root (Huangqin) serve as the sovereign drugs, while Forsythia Fruit (Lianqiao), Angelica Dahurica (Baizhi), and the root of Cistanches (Xuduan) serve as ministering drugs.
I believe that for the aforementioned symptoms, sweating methods to release the exterior should also be considered. Regardless of whether the pustules have erupted or not, or whether they have crusted over or not, if convulsions are triggered by external pathogenic factors damaging the exterior and internal fire stirring within:
If convulsions occur before eruption, it is due to heat-toxin accumulation internally; use Zicao Kaban Tang (Purple Gromwell Decoction for Rapid Eruption) with Uncaria rhynchophylla (Gouteng).
If convulsions occur after eruption when the pustules are red and blooming, it is due to pain caused by heat-toxin; use Dongyuan Xiaodu San (Dongyuan's Detoxification Powder) with Uncaria rhynchophylla (Gouteng).
If convulsions occur during the suppuration stage, it is due to deficiency of Qi and Blood; use Renshen Sisheng San (Ginseng Four-Sage Powder) with Uncaria rhynchophylla (Gouteng).
If convulsions occur after crusting, it is due to further deficiency of Qi and Blood; use Bazhen Tang (Eight-Treasure Decoction) with Uncaria rhynchophylla (Gouteng).
If there is strabismus or fixed gaze, it is due to the struggle between wind and fire; use Chaihu Zhizi San (Bupleurum and Gardenia Powder) or Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill) with Bupleurum Root (Chaihu) and Gardenia Fruit (Shanzhi).
If there is drooling from the corners of the mouth, it is due to Liver Wood overacting on Spleen Earth; use Wuwei Yigong San (Five-Ingredient Extraordinary Merit Powder) with Cimicifuga Rhizome (Shengma), Bupleurum Root (Chaihu), and Uncaria rhynchophylla (Gouteng).
If there is redness of the eyes with excessive discharge and tearing, it is due to wind generated by Liver Blood deficiency; use Siwu Tang (Four-Substance Decoction) with Bupleurum Root (Chaihu) and Uncaria rhynchophylla (Gouteng).
If opisthotonos occurs, it is due to Water failing to generate Wood (Kidney Water deficiency failing to nourish Liver Wood); use Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill) with Bupleurum Root (Chaihu) and Angelica Sinensis (Danggui), followed by appropriate use of Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) with Gastrodia Rhizome (Tianma) and Uncaria rhynchophylla (Gouteng). Do not directly use wind-dispersing drugs. This is because wind-dispersing herbs can dry the Blood and scatter Qi. One must verify the condition based on three signs: the temperature and warmth of the hands and feet, and then apply tonifying or purging regulation methods, so as to avoid errors. For infants, one should examine the nursing mother and treat accordingly.
A child suffered convulsions as his smallpox was about to erupt. After taking Niuhuang Qingxin Wan (Calculus Bovis Heart-Clearing Pill), he developed trismus and drooling. This indicated that the Spleen and Stomach were injured again, and Liver Wood bullied the Spleen, causing saliva to fail to return to its vessels. First, Wuwei Yigong San (Five-Ingredient Extraordinary Merit Powder) with Uncaria rhynchophylla (Gouteng) was used, and all symptoms instantly decreased. Subsequently, Wuwei Yigong San (Five-Ingredient Extraordinary Merit Powder) with Bupleurum Root (Chaihu) brought recovery.
A woman developed convulsions due to anger while suffering from smallpox. Her scar marks were red, she was irritable and thirsty, and her face and eyes were red. This was caused by excessive sweating leading to Yang collapse and Blood loss. First, Danggui Buxue Tang (Angelica Tonifying Blood Decoction) was administered for two doses, and the irritability and thirst stopped instantly. Then, Bazhen Tang (Eight-Treasure Decoction), Bupleurum Root (Chaihu), Moutan Cortex (Mudanpi), and Uncaria rhynchophylla (Gouteng) were used, curing the fever and convulsions completely. Finally, she recovered using Bazhen Tang (Eight-Treasure Decoction).
A woman suffered convulsions, trismus, and splitting headaches due to anger as her smallpox was nearing cure. Her scar marks were pale white. She was cured instantly using Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) with Vitex Fruit (Manjingzi) and Uncaria rhynchophylla (Gouteng). Later, due to anger, she suffered convulsions again with dizziness and loss of appetite. She was first treated with Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) plus Gastrodia Rhizome (Tianma), and subsequently stabilized with Liujunzi Tang (Six-Gentleman Decoction) and Bupleurum Root (Chaihu).
Danggui Buxue Tang (Angelica Tonifying Blood Decoction): Treats smallpox where Qi and Blood are deficient, causing convulsions, fever, thirst with desire to drink, and a pulse that is large and forceful yet empty upon heavy pressure. (Formula see entry 'Chills and Teeth Grinding')
Baolong Wan (Embracing Dragon Pill): Treats convulsions caused by wind-heat in smallpox, or severe phlegm.
Ingredients: Danxing (Arisaema Cum Bile, 4 liang), Tianzhuhuang (Calamus Tuber, 1 liang), Xionghuang (Realgar), Zhusha (Cinnabar, each 5 qian), Shexiang (Musk, a small amount).
Preparation: Grind into fine powder. Use Licorice Root (Gancao, 1 jin) decocted into paste to form pills. Each liang of powder makes 20 pills. Administer dissolved in Mint Tea or Juncus Effusus (Dengxin) tea.
Note: The previous formulas contain herbs for clearing heat, resolving phlegm, regulating Qi, and dispelling wind targeting the Liver channel. Overuse will re-injure the Spleen and Lung, worsening the condition. If chest/abdominal distension, poor appetite, or vomiting occur, use Renshen Baizhu San (Ginseng and Atractylodes Macrocephala Powder) to strongly tonify Middle Qi.
Method for Preparing Arisaema Cum Bile (Niu Dan Nanxing): In the twelfth lunar month, select large Arisaema Rhizomes (Nanxing), grind them into powder, mix evenly with bile from a yellow cow, place back into the gallbladder shell, tie the opening with thread, and hang in a ventilated place to dry in the shade. It can be used only after one year. Re-processing two or three times is especially excellent.
Xiao Chaihu Tang (Minor Bupleurum Decoction) (Formula see entry 'Malaria')
Chaihu Lian'er Wan (Bupleurum and Coptis Two-Ingredient Pill) (Formula see above)
Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill) (Formula see entry 'Fever Belonging to Yin and Yang')
Siwu Tang (Four-Substance Decoction) (Formula see entry 'Delayed Smallpox Eruption')
Shiquan Dabu Tang (Ten-Ingredient Great Tonifying Decoction) (Formula see entry 'Abdominal Distension and Shortness of Breath')