陈文宿先生云∶痘疹已靥未愈之间，五脏未实，肌肉尚虚，血气未定，忽被风邪搏于肌肉肤肌之间，则津液涩滞，
故成疳蚀疮也。宜用雄黄散、绵茧散治之。久而不愈，则溃蚀筋蚀，以致杀人。窃谓雄黄散清肝杀虫解毒，绵茧散治脓
水淋漓，皆治外之良方，内无余毒者，宜用此法。若因肝脾疳火上炎，或食甘肥而胃火内动，或手足阳明经蕴热，或肾
经虚热，各有不同，皆元气不足，病气有余，乘虚而发也。 痛作肿，用仙方活命饮、大芜荑汤。疳热为患，用大芜荑
汤、四味肥儿丸。肾经虚热，用地黄丸。当临制宜，分五脏相胜，审乳母之气何如，扶助胃气为善。
一女子患疳症，因浴热汤，发热如炎，体强如 ，此腠理间泄邪热乘虚而内作，用十全大补汤一剂顿安。同时亦有
患此症，不用补剂者，甚至不救。
一小儿痘后，遍身津淫作痒，此兼因疳为患，用大芜荑汤及蟾蜍丸而愈。后作渴，口中作痛，用蟾蜍丸、人中白散
而安。
一小儿痘后毒蚀腮，余谓肝脾有热助疳而患也，用大芜荑汤、大芦荟丸为主，以五味异功散为佐，月余渐愈，却以
五味异功散，佐以大芜荑汤而痊。
一小儿臀间痘毒蚀烂，恪敷雄黄散益甚，余谓兼肝脾疳也，先用大芜荑汤、活命饮各二剂，又用九味芦荟丸为主，
以五味异功散为佐，月余诸症渐愈。
一小儿患前症，发热作渴，两足晡热，余谓禀肾经阴虚，不信，恪服清热败毒而殁。
一小儿痘出甚密，先四肢患毒脓溃而愈，后口患疳延蚀牙龈，余先用大芜荑汤、活命饮各一剂，又用蟾蜍丸、人中
白散而安。
一小儿痘毒蚀陷，敷雄黄散，服加味解毒散而愈。
一小儿脸患之作痛，用仙方活命饮，又敷雄黄散、大芜荑汤而愈。
韶粉散 治痘疮毒瓦斯未散，疮痂虽落，其瘢犹黯，或凹或凸，此药涂之。
韶粉（一两） 轻粉（一两）
上炼猪脂油拌匀如膏涂之。如痘痂欲落不落，当用后方。
羊 骨髓
上入轻粉研成膏涂之。如痘痒搔成疮及疮痂欲落不落，用上等白蜜涂之，其痂自落，亦无瘢痕，神效。
雄黄散 治痘毒牙龈生疳蚀疮。
雄黄（一钱） 铜绿（二钱）
上研细，量疮大小干掺。
绵茧散 治痘毒蚀疮，脓水不绝。
出蛾绵茧（不拘多少）
上用生矾末碎贯茧内，以炭灰烧矾汁干，取出为末，干贴之。
九味芦荟丸 治痘毒成疳，齿蚀烂龈，或透颊腮，或肝脾疳热结核，耳内生疮，两目生翳，耳中出水，或小便
出津，拗中结核，或大便不调，肢体消瘦等症。
胡黄连 宣黄连（炒） 芦荟 木香 白芜荑（炒） 青皮 白雷丸 鹤虱草（各一两） 麝香（三钱）
上各另为末，糊丸麻子大。每服半钱，空心米汤下。仍量儿用之。
大芜荑汤（一名栀子茯苓汤） 治痘疮上攻，口齿成疳，发热作渴，大便不调，发黄脱落，面黑便清，鼻下生
疮，乳食呕吐等症。
山栀仁（三分） 黄柏 甘草（炙。各二分） 大芜荑（五分） 黄连 麻黄根（一分） 羌活（二分） 柴胡（三
分） 防风（一分） 白术 茯苓（各五分） 当归（四分）
上水煎服。
导赤散
生地黄 木通 甘草（各等分）
上为末，每服一钱，淡竹叶水煎。
败草散 治痘疮挝搔成疮，脓血淋漓，用屋烂草，或盖墙烂茅，年远者佳，如无，旷野生者尤佳，为末搽之。
如遍身患者，须多掺铺席上，令儿坐卧，其疮即愈。
丹粉散 治痘毒脓水淋漓。
轻粉 黄丹（各一钱） 黄连末（三钱）
上研匀搽患处。
立效散 治一切胎毒疮疥及风疹痛。
大黄 黄柏 山栀 寒水石（ 。各等分）
上为末，用清油烛调搽。若破而脓水淋漓，用当归膏。
大枫膏 治一切疮疥。
大枫子肉（研膏） 黄连（各二两） 真轻粉 枯矾 蛇床子（各一两） 地沥青（六两）
上各另为末，入大枫膏和匀，更入地沥青杵百余即成膏矣。每用少许涂患处。
加味小柴胡汤（方见 疹）
加味逍遥散（方见欲靥不靥）
人参平肺散
犀角地黄汤（二方见顶陷心烦）
柴胡栀子散（方见作痒抓破）
三黄散（方见 烂）
八珍散（方见顶陷灰白）
地黄丸（方见发热属阴阳）
十全大补汤（方见腹胀气促）
补中益气汤
当归补血汤
五味异功散
竹叶石膏汤（四方见泄泻切牙）
四味肥儿丸
加味解毒散
人中白散
东垣消毒救苦汤（四方见夹疹痘）
蟾蜍丸
清胃散
仙方活命饮（三方见痘痈）
陈文宿先生说：在痘疹结痂脱落但尚未完全痊愈的期间，五脏功能尚未充实，肌肉腠理依然虚弱，血气运行尚未稳定。此时如果突然受到风邪侵袭，搏结于肌肉与皮肤之间，就会导致津液运行涩滞不畅，从而形成疳蚀疮。适宜使用雄黄散、绵茧散来治疗。如果病情迁延不愈，就会溃烂侵蚀筋脉骨骼，甚至导致死亡。我认为雄黄散能清肝火、杀虫解毒，绵茧散能治疗脓水淋漓不止，这些都是治疗外部病症的良好方剂；对于体内没有余毒的患者，适宜采用这种方法。如果是由于肝脾疳火上炎，或者因为食用甘甜肥腻食物导致胃火内动，或者是手足阳明经蕴积热邪，又或是肾经虚热，情况各不相同，但根本原因都是元气不足而病邪有余，乘虚而入而发病。出现疼痛肿胀时，使用仙方活命饮、大芜荑汤。疳热为患时，使用大芜荑汤、四味肥儿丸。肾经虚热时，使用地黄丸。应当根据具体情况灵活变通，分辨五脏之间的相克关系，审察乳母的气血状况，以扶助胃气为最佳策略。
有一个女子患疳症，因为用热水洗澡，导致发热如火烧，身体僵硬强直，这是腠理间泄出的邪热乘虚内侵所致，服用一剂十全大补汤后立刻安宁。同时也有患此症的人，不使用补益药剂的，甚至无法挽救。
有一个小儿出痘后，全身津液渗出且瘙痒，这是因为兼有疳症为患，使用大芜荑汤及蟾蜍丸而痊愈。后来出现口渴，口中疼痛，使用蟾蜍丸、人中白散而安定。
有一个小儿出痘后，痘毒侵蚀腮部，我认为这是肝脾有热助长疳症所致，以大芜荑汤、大芦荟丸为主药，以五味异功散为辅佐，一个多月后逐渐痊愈，最后单用五味异功散，辅加大芜荑汤而康复。
有一个小儿臀部之间痘毒侵蚀腐烂，严格敷用雄黄散反而加重，我认为这是兼有肝脾疳症，先用大芜荑汤、仙方活命饮各两剂，又用九味芦荟丸为主药，以五味异功散为辅佐，一个多月后各种症状逐渐痊愈。
有一个小儿患前述病症，发热口渴，两足在傍晚时分发热，我认为这是禀受肾经阴虚体质，患者不信，坚持服用清热败毒药物而死亡。
有一个小儿出痘非常密集，先四肢患毒脓溃破后痊愈，后来口腔患疳症蔓延侵蚀牙龈，我先用大芜荑汤、仙方活命饮各一剂，又用蟾蜍丸、人中白散而安定。
有一个小儿脸部患病疼痛，使用仙方活命饮，又敷用雄黄散、大芜荑汤而痊愈。
韶粉散：治疗痘疮毒气未散，疮痂虽然脱落，但疤痕仍然暗黑，或凹陷或凸起，此药涂抹可治。
韶粉（一两） 轻粉（一两）
以上药材炼猪脂油拌匀如膏状涂抹。如果痘痂欲落不落，应当使用后方。
羊骨髓
以上加入轻粉研成膏状涂抹。如果痘痒抓挠成疮以及疮痂欲落不落，用上等白蜜涂抹，其痂皮自然脱落，也没有瘢痕，神效。
雄黄散：治疗痘毒导致牙龈生疳蚀疮。
雄黄（一钱） 铜绿（二钱）
以上研细，根据疮口大小干掺。
绵茧散：治疗痘毒侵蚀疮疡，脓水不绝。
出蛾绵茧（不拘多少）
以上用生矾末碎穿贯入茧内，用炭灰烧干矾汁，取出研为粉末，干贴患处。
九味芦荟丸：治疗痘毒成疳，牙齿侵蚀腐烂牙龈，或穿透脸颊腮部，或肝脾疳热形成的结核，耳内生疮，两目生翳，耳中出水，或小便排出津液，腋下结核，或大便不调，肢体消瘦等症状。
胡黄连 宣黄连（炒） 芦荟 木香 白芜荑（炒） 青皮 白雷丸 鹤虱草（各一两） 麝香（三钱）
以上各药分别研为粉末，用糊制成梧桐子大小的丸药。每次服用半钱，空腹米汤送服。仍应根据儿童年龄用量调整。
大芜荑汤（又名栀子茯苓汤）：治疗痘疮上攻，口齿成疳，发热口渴，大便不调，发黄脱落，面黑便清，鼻下生疮，乳食呕吐等症状。
山栀仁（三分） 黄柏 甘草（炙。各二分） 大芜荑（五分） 黄连 麻黄根（一分） 羌活（二分） 柴胡（三分） 防风（一分） 白术 茯苓（各五分） 当归（四分）
以上用水煎服。
导赤散
生地黄 木通 甘草（各等分）
以上研为粉末，每次服用一钱，淡竹叶水煎服。
败草散：治疗痘疮抓挠成疮，脓血淋漓，使用屋顶烂草，或墙头烂茅草，年代久远的更好，如果没有，旷野生长的尤佳，研为粉末搽涂。如果遍身患病，须多掺铺在席子上，让孩子坐卧其上，疮即痊愈。
丹粉散：治疗痘毒脓水淋漓。
轻粉 黄丹（各一钱） 黄连末（三钱）
以上研匀搽涂患处。
立效散：治疗一切胎毒疮疥及风疹痛。
大黄 黄柏 山栀 寒水石（煅。各等分）
以上研为粉末，用清油烛调搽。如果破溃而脓水淋漓，使用当归膏。
大枫膏：治疗一切疮疥。
大枫子肉（研膏） 黄连（各二两） 真轻粉 枯矾 蛇床子（各一两） 地沥青（六两）
以上各药分别研为粉末，加入大枫膏和匀，再加入地沥青杵捣百余次即成膏。每次取少许涂患处。
加味小柴胡汤（方见 疹）
加味逍遥散（方见欲靥不靥）
人参平肺散
犀角地黄汤（二方见顶陷心烦）
柴胡栀子散（方见作痒抓破）
三黄散（方见 烂）
八珍散（方见顶陷灰白）
地黄丸（方见发热属阴阳）
十全大补汤（方见腹胀气促）
补中益气汤
当归补血汤
五味异功散
竹叶石膏汤（四方见泄泻切牙）
四味肥儿丸
加味解毒散
人中白散
东垣消毒救苦汤（四方见夹疹痘）
蟾蜍丸
清胃散
仙方活命饮（三方见痘痈）
Mr. Chen Wensu said: During the period when smallpox pustules have crusted and fallen off but have not yet fully healed, the functions of the five zang organs are not yet solid, the muscles and cou li (skin and interstices) remain deficient, and the blood and qi circulation is not yet stable. If suddenly attacked by wind-pathogen combing with the muscles and skin, the body fluids will become stagnant and sluggish, thus forming gan-erosion sores (ulcers caused by parasitic or toxic erosion). It is suitable to use Xionghuang San (Realgar Powder) and Mianjian San (Silkworm Cocoon Powder) for treatment. If the condition persists without healing, it will ulcerate and erode tendons and bones, eventually leading to death. I believe that Xionghuang San clears liver heat, kills parasites, and detoxifies; Mianjian San treats continuous oozing of pus and water. Both are excellent external formulas. For patients without residual internal toxins, this method is appropriate. However, if the cause is liver-spleen gan-fire flaring upward, or stomach fire moving internally due to consuming sweet and greasy foods, or heat accumulation in the hand-foot yangming meridians, or deficiency heat in the kidney meridian, the situations vary. The root cause is always insufficient yuan qi (original qi) and excess pathogenic qi, taking advantage of the deficiency to manifest. When pain and swelling occur, use Xianfang Huoming Yin (Immortal Formula for Activating Life Decoction) and Da Wuyi Tang (Large Trogopterus Dung Decoction). When gan-heat causes pathology, use Da Wuyi Tang and Siwei Fei'er Wan (Four-Ingredient Stomach-Strengthening Pills). For kidney meridian deficiency heat, use Dihuang Wan (Rehmannia Pill). One should apply flexibility according to the specific situation, differentiate based on the mutual overcoming relationship among the five zang organs, assess the mother's qi status during breastfeeding, and prioritize supporting stomach qi as the best approach.
A woman suffered from gan syndrome. After bathing in hot water, she developed fever like burning flames and rigid stiffness of the body. This was due to pathogenic heat leaking from the cou li invading internally due to deficiency. She took one dose of Shiquan Dabu Tang (Ten-Agent Great Supplement Decoction) and was immediately relieved. At the same time, others suffering from this condition did not use tonifying agents and even died.
A child, after recovering from smallpox, had whole-body exudation and itching. This was complicated by gan syndrome. He recovered after using Da Wuyi Tang and Chan Chu Wan (Toad Pill). Later, he developed thirst and mouth pain, which were resolved using Chan Chu Wan and Renzhongbai San (Human Tooth Ash Powder).
A child suffered from smallpox toxin eroding the cheeks. I reasoned that liver-spleen heat assisted the gan syndrome. The main treatment was Da Wuyi Tang and Da Lushui Wan (Large Aloe Pill), assisted by Wuwei Yigong San (Five-Ingredient Extraordinary Merit Powder). After more than a month, symptoms gradually improved. Finally, cured by using Wuwei Yigong San alone, assisted by Da Wuyi Tang.
A child suffered from smallpox toxin eroding and rotting the buttocks. Strict application of Xionghuang San worsened the condition. I diagnosed concurrent liver-spleen gan syndrome. Initially, two doses each of Da Wuyi Tang and Xianfang Huoming Yin were used. Then, Jiawei Lushui Wan (Nine-Ingredient Aloe Pill) was used as the main formula, assisted by Wuwei Yigong San. After more than a month, all symptoms gradually healed.
A child suffered from the aforementioned symptoms, with fever, thirst, and afternoon heat in both feet. I diagnosed congenital yin deficiency of the kidney meridian. The patient did not believe this and insisted on taking heat-clearing and detoxifying herbs, resulting in death.
A child had very dense smallpox eruptions. First, limbs suffered from toxic pus ulcers which healed. Later, oral gan spread to erode the gums. I initially used one dose each of Da Wuyi Tang and Xianfang Huoming Yin, then stabilized the condition with Chan Chu Wan and Renzhongbai San.
A child suffered from sunken smallpox toxin erosion. Application of Xionghuang San and ingestion of Jiawei Jiedu San (Modified Detoxification Powder) led to recovery.
A child suffered from facial lesions causing pain. Treatment with Xianfang Huoming Yin, combined with topical Xionghuang San and internal Da Wuyi Tang, resulted in recovery.
Shaofen San (Pearl Powder): Treats cases where smallpox toxin qi has not dissipated. Although scabs have fallen, scars remain dark, depressed, or raised. Apply this powder topically.
Shaofen (1 liang) Qingfen (1 liang)
Mix refined lard oil into a paste and apply. If scabs are reluctant to fall, use the following prescription.
Sheep Bone Marrow
Grind with Qingfen into a paste and apply. If itching leads to sores and scabs are reluctant to fall, apply high-quality white honey. The scabs will fall naturally without leaving scars. This is miraculous.
Xionghuang San (Realgar Powder): Treats gum gan-erosion sores caused by smallpox toxin.
Xionghuang (1 qian) Tonglv (2 qian)
Grind finely. Apply dry powder according to the size of the sore.
Mianjian San (Silkworm Cocoon Powder): Treats smallpox toxin erosive sores with continuous oozing.
Silkworm cocoon from emerging moths (any amount)
Crush raw alum powder and thread it through the cocoon. Burn with charcoal ash until the alum juice dries. Remove and grind into powder. Apply dry powder to the site.
Jiuwei Lushui Wan (Nine-Ingredient Aloe Pills): Treats smallpox toxin turning into gan, teeth eroding rotten gums, penetration through cheeks, liver-spleen gan-heat nodules, ear sores, corneal opacity in eyes, otorrhea, discharge from urethra, axillary nodules, irregular bowel movements, emaciation, etc.
Huhuanglian (Picrorhiza Rhizome) Xuanhuanglian (Scutellaria Root, stir-fried) Lushui (Aloe) Muxiang (Costus Root) Baiwuyi (Trogopterus Dung, stir-fried) Qingpi (Green Tangerine Peel) Bileiwanz (Polyporus Umbellatus) Heshiqicao (Chrysanthemum Caravonicum Herb) (each 1 liang) Shexiang (Musk) (3 qian)
Grind each ingredient separately into powder. Make pills with paste, sized like hemp seeds. Take half a qian per dose, with rice water on an empty stomach. Adjust dosage according to the child's age.
Da Wuyi Tang (Large Trogopterus Dung Decoction), also known as Zhizi Fuling Tang: Treats smallpox toxin attacking upwards, oral/dental gan, fever with thirst, irregular bowel movements, yellowing and shedding of hair/nails, dark face with clear urine, sores under the nose, vomiting of milk/food, etc.
Shanzhiren (Gardenia Seed) (3 fen) Huangbo (Phellodendron Bark) Gancao (Licorice Root, honey-fried) (each 2 fen) Dawuyi (Trogopterus Dung) (5 fen) Huanglian (Coptis Rhizome) Mahuanggen (Ephedra Root) (1 fen) Qianghuo (Notopterygium Rhizome) (2 fen) Chaihu (Bupleurum Root) (3 fen) Fangfeng (Saposhnikovia Root) (1 fen) Baizhu (Atractylodes Macrocephala Rhizome) Fuling (Poria) (each 5 fen) Danggui (Angelica Sinensis Root) (4 fen)
Decoct in water and take orally.
Daochi San (Guide Out Redness Powder)
Shengdihuang (Rehmannia Root) Mutong (Akebia Stem) Gancao (Licorice Root) (equal parts)
Grind into powder. Take 1 qian per dose, decocted with Danzhuye (Young Bamboo Leaf) water.
Baicao San (Rotten Grass Powder): Treats sores caused by scratching smallpox, with dripping pus and blood. Use rotten grass from roofs or old thatch from walls; older is better. If unavailable, wild grass is excellent. Grind into powder and apply. If the whole body is affected, sprinkle generously on mats for the child to sit or lie on. The sores will heal.
Danfen San (Cinnabar Powder): Treats smallpox toxin with dripping pus.
Qingfen (Calomel) Huangdan (Lead Oxide) (each 1 qian) Huanglianmo (Coptis Powder) (3 qian)
Grind evenly and apply to the affected area.
Lixiao San (Instant Effect Powder): Treats all types of fetal toxin sores, scabies, and wind-rash pain.
Dahuang (Rhubarb Root) Huangbo (Phellodendron Bark) Shanzhi (Gardenia Fruit) Hanshuishi (Calcined Aragonite) (calcined, equal parts)
Grind into powder. Mix with clarified oil candle wax and apply. If broken with dripping pus, use Danggui Gao (Angelica Ointment).
Dafeng Gao (Large Maple Oil Paste): Treats all types of sores and scabies.
Dafengzirou (Large Maple Seed Flesh, ground into paste) Huanglian (Coptis Rhizome) (each 2 liang) Zhenqingfen (Pure Calomel) Kufan (Calcined Alum) Shechuangzi (Cnidium Fruit) (each 1 liang) Diqingting (Bitumen) (6 liang)
Grind each ingredient separately into powder. Mix with Dafengzi paste. Add bitumen and pound over a hundred times until it becomes a paste. Apply a small amount to the affected area.
Jiawei Xiaochaihu Tang (Modified Minor Bupleurum Decoction) (See Prescription for Rash)
Jiawei Xiaoyao San (Modified Free and Easy Wanderer Powder) (See Prescription for Hesitant Crusting)
Renshen Pingfei San (Ginseng Lung-Calming Powder)
Xijiao Dihuang Tang (Rhino Horn Rehmannia Decoction) (Two prescriptions see Sunken Crown and Restlessness)
Chaihu Zhizi San (Bupleurum Gardenia Powder) (See Prescription for Itching and Scratching)
Sanhuang San (Three-Yellow Powder) (See Prescription for Rotting)
Bazhen San (Eight-Treasure Powder) (See Prescription for Sunken Crown and Ashy White)
Dihuang Wan (Rehmannia Pill) (See Prescription for Fever Belonging to Yin/Yang)
Shiquan Dabu Tang (Ten-Agent Great Supplement Decoction) (See Prescription for Abdominal Distension and Shortness of Breath)
Buzhong Yiqi Tang (Middle-Warding Qi-Supplementing Decoction)
Danggui Buxue Tang (Angelica Blood-Supplementing Decoction)
Wuwei Yigong San (Five-Ingredient Extraordinary Merit Powder)
Zhuye Shigao Tang (Bamboo Leaf Gypsum Decoction) (Four prescriptions see Diarrhea and Teeth-Gnashing)
Siwei Fei'er Wan (Four-Ingredient Stomach-Strengthening Pills)
Jiawei Jiedu San (Modified Detoxification Powder)
Renzhongbai San (Human Tooth Ash Powder)
Dongyuan Xiaodu Jiuku Tang (Dongyuan Toxin-Clearing Salvation Decoction) (Four prescriptions see Complicated Rash and Smallpox)
Chan Chu Wan (Toad Pill)
Qingwei San (Stomach-Clearing Powder)
Xianfang Huoming Yin (Immortal Formula for Activating Life Decoction) (Three prescriptions see Smallpox Abscess)