痘疮之后，有因热毒未解，并于小肠而小便不通者宜利之。利而不参通者。则宜升
提清解，上窍通而下窍自利矣。更莫如清肺，肺气清而下输膀胱也。尤莫若养阴，肾
阴得而自能行水也。若并于大肠而大便不通者，治宜下之，然痘后必虚，亦莫若养血，
肠得血而自解也。更有泄泻者。所属有二，泄泻而能食者，邪热杀谷也。口渴者，邪灼
津液也。脉盛者，内热也。脉盛而数者。邪热炽也。此为热入大肠而泄泻，宜清利之
如食少不渴，脉微小者，此里气虚，不能禁固水谷也。虽有小渴，亦津液耗损使然，治
以理中汤加减。然至痘后，则气血大虚。凡遇泻利，多从温补，宽可以不足之法治有
余，惟便痂皮脓血者，此热毒入于大肠而利出，宜四物汤，加芩连之类。待其利尽自愈。不可 用劫涩也。
靥后阴囊肿痛，胞胀如瓜者，是热结膀胱也。治法有三，或疏肝以令展其疏泄之
权。或清肺以得下输降化之职，或直取膀胱，清利其热散其结气，兼与利水，宜分虚
实，以投所宜。实者，直治本脏∶虚者间脏治之，外用椒盐葱头地肤子煎汤熏洗。以导散结气可也。
痘后呕吐者，虽多主余毒在胃，然有冷热二症。如心烦作渴，食乳甚急，聚满胸
中，而后吐出如射，其人面色带赤，手足心热，居处喜凉，或吐而且渴且泻者，此热毒
也。如乳食水浆而随吐，其人面色青白，手足俱冷，二便清利，及吐而不渴，泻而手足
心冷者，此冷吐也。余毒热邪者，十有七八，胃虚挟冷者，十有二三。更有伤食而呕
者，但闻食臭即吐而不能食是也，宜木香大安丸。有渴欲饮水，水入即吐者，此名水
逆，乃邪热挟积饮上逆也，宜五苓散主之。
痘疮痊愈后，若因热毒未能清除，并传入小肠导致小便不通的，适宜采用通利的方法治疗。如果单纯使用通利法而效果不佳，则应当采用升提清气、解除郁热的治法，上窍通畅后下窍自然也就通利了。更好的方法是清肺，肺气清肃则能向下输布津液至膀胱。尤其重要的是滋养阴液，肾阴得到补充则能自行推动水液运行。
如果热毒并入大肠导致大便不通的，治疗适宜采用攻下法。然而痘后身体必然虚弱，因此更适宜采用养血的方法，肠道得到血液濡润则大便自然通畅。
此外还有出现泄泻的情况，主要归属两类：泄泻且食欲正常的，是邪热加速谷物消化所致；口渴的，是邪热灼伤津液所致；脉象有力的，是体内有热；脉象有力且快的，是邪热炽盛。这属于热邪侵入大肠引起的泄泻，适宜采用清热利湿的方法治疗。如果是食量减少且不口渴，脉象细微的，这是里气虚弱，不能固摄水谷所致。即使有轻微口渴，也是津液耗损造成的，治疗应使用理中汤加减。但是到了痘后阶段，气血大虚。凡是遇到泄泻，大多从温补角度治疗，宽缓地用不足之法治有余之证（指以补为通）。只有那些排出痂皮、脓血的，这是热毒进入大肠导致的痢疾样泄泻，适宜使用四物汤，加入黄芩、黄连之类药物。等待病邪排尽后自愈，不可使用强行收敛止涩的药物。
痘疹结痂后，阴囊肿胀疼痛，像瓜一样大的，这是热邪结聚在膀胱。治疗方法有三种：或者疏肝以恢复其疏泄的功能；或者清肺以获得向下输布和降化的职能；或者直接针对膀胱，清利其热邪并解散结聚之气，同时配合利水。应当辨别虚实，投以适宜的药物。实证者，直接治疗本脏；虚证者，通过相生关系间接治疗（间脏治之）。外用花椒、盐、葱头、地肤子煎汤熏洗，以引导消散结聚之气即可。
痘后呕吐，虽然多主因余毒留在胃中，但有冷症和热症两种。如心烦口渴，吃奶非常急切，食物积聚在胸中，随后喷射状吐出，面色带红，手足心发热，喜欢居住在凉爽环境，或者吐而且渴且泻的，这是热毒所致。如喝奶进食或饮水后立即呕吐，面色青白，手脚冰凉，大小便清长通畅，以及呕吐但不口渴，腹泻但手足心冷的，这是冷吐。余毒热邪引起的占十之七八，胃虚夹寒引起的占十之二三。还有因伤食而呕吐的，只要闻到食物气味就呕吐且不能进食，适宜使用木香大安丸。有想喝水，水喝进去就吐出来的，这叫“水逆”，是邪热挟带停饮向上冲逆所致，适宜用五苓散主治。
After the eruption of smallpox (or chickenpox), if heat-toxin remains unresolved and affects the Small Intestine (Small Intestine, an organ responsible for separating clear from turbid fluids) causing urinary retention, it is appropriate to promote urination. If promoting urination alone does not lead to improvement, one should employ methods to raise clear Yang and resolve heat; once the upper orifices are unblocked, the lower orifices will naturally become patent. Even better is to clear the Lungs; when Lung Qi is clear, it can transmit fluids downward to the Bladder. Most importantly, nourishing Yin is crucial; when Kidney Yin is replenished, it can naturally facilitate water metabolism.
If the toxin affects the Large Intestine causing constipation, purgation is indicated. However, since the post-smallpox state involves deficiency, nourishing Blood is preferable; when the intestines receive adequate blood nourishment, stool passage will naturally resume.
Regarding diarrhea following smallpox, there are two main categories: Diarrhea accompanied by normal appetite indicates that pathogenic heat accelerates digestion ("killing grains"); thirst indicates that pathogenic heat scorches body fluids; a forceful pulse indicates internal heat; a forceful and rapid pulse indicates intense pathogenic heat. This constitutes diarrhea due to heat entering the Large Intestine, treated with clearing heat and promoting diuresis. Conversely, if appetite is poor, there is no thirst, and the pulse is fine and weak, this indicates deficiency of interior Qi failing to secure food and fluids. Even slight thirst in this context results from fluid depletion; treatment should involve modifying Lizhong Tang (Regulate the Middle Decoction). Given the significant Qi and Blood deficiency after smallpox, diarrhea is generally treated with warming and tonifying methods, applying gentle tonification to address excess symptoms (treating deficiency as if it were excess by supporting the root). However, for cases involving discharge of crusts, pus, and blood—indicating heat-toxin entering the Large Intestine causing dysentery-like discharge—Siwu Tang (Four Substances Decoction) added with Scutellariae Radix (Huangqin) and Coptidis Rhizoma (Huanglian) is suitable. The condition will resolve spontaneously after the pathogen is expelled; one must not use astringents to forcibly stop diarrhea.
Following the crusting stage, swelling and pain of the scrotum, resembling a melon, indicates heat binding in the Bladder. There are three treatment approaches: One may soothe the Liver to restore its function of free flow and excretion; one may clear the Lungs to restore their function of descending and transforming fluids; or one may directly treat the Bladder by clearing heat, dissipating bound Qi, and promoting diuresis. Differentiation between excess and deficiency is essential to select appropriate therapy. For excess patterns, treat the affected organ directly; for deficiency patterns, treat via the generating cycle (inter-organ treatment). Externally, fumigate and wash with a decoction of Zanthoxyli Pericarpium (Huajiao), Salt, Allii Cepae Bulbus (Congtou), and Kochiae Fructus (Difuzi) to guide the dispersion of bound Qi.
Vomiting after smallpox is mostly attributed to residual toxins in the Stomach, but presents as either cold or heat syndromes. Symptoms such as mental restlessness, thirst, urgent feeding, accumulation in the chest followed by projectile vomiting, reddish complexion, hot palms and soles, preference for cool environments, or simultaneous vomiting, thirst, and diarrhea, indicate heat-toxin. In contrast, immediate vomiting after milk/food intake, bluish-white complexion, cold extremities, clear urine and loose stools, vomiting without thirst, or diarrhea with cold palms and soles, indicate cold vomiting. Heat-toxin accounts for 70-80% of cases, while Stomach deficiency with cold accounts for 20-30%. Vomiting due to food stagnation is characterized by vomiting upon smelling food and inability to eat; Muxiang Da'an Wan (Aucklandia Peaceful Digestion Pill) is indicated. Polydipsia with immediate vomiting upon drinking water is termed "Water Rebellion" (Shuini), caused by pathogenic heat carrying retained fluid upward; Wuling San (Five Ingredient Powder with Poria) is the primary prescription.