妇女梅毒，犯于阳明，致乳房烂深似陷，全不肿痛，时流臭清水，乳汁常通，以此可
辨。
梅毒下注三阴，腿胫烂黑或紫暗色，时淌臭水，中有竖头肉，凸凹如嵌珍珠形，大
小不定，名落底结毒，极难全效。
兵兴日久之处，必有恶厉气横亘其间，兼有马溺流入河井，虚体及劳伤人，易受其毒。
入于肺胃，淫于肌肉，达于皮肤。先发小红疙瘩，渐如梅李，臭烂翻花，内有竖头肉，为
野杨梅者。不由精气传染而来，治法同梅疮。易效。
玉茎有烂至逐段脱去平根者，外搽珠黄散，内服败毒方，渐可收功。若肿硬臭烂，治
之不应者，难廖。若肿似猪肝色者，不治。
霍乱，头额与周身全不发热，只有头眩烦闷，上吐下泻者。若不吐泻，惟腹痛甚，为
搅肠痧。果时感头面身腹总发热，医者须用右手按摸病患头与胸腹方知。若妇女，令彼
自家内眷按摸可也。
痈疽溃脓日久，患口时淌稀脓，或流清水，终难完口。或完口未久又发，必脓毒瘀
结成管。用降药条插患口中，贴膏药，过七日管自出，再上收口药可愈。夫降药用水银
降成，其性与砒霜相等，猛烈烂痛，不可轻用。少壮者，可少用。若幼孩老人及虚体者，
用之生变。但痛甚，则浮火上攻，口舌与牙根糜烂者，用生麦益阴煎（方见后）。凡口中、眼
边、耳中、鼻内，并心窝、腰眼、玉茎、红筋聚处，血瘤、气瘤，总不可用，关人性命。
从来只知其利，未知其害。今有一变险为平法，用降药三分，生石膏七分，糯米饭汁捣
和作条，亦能追拔恶腐收口，内宜投调养方。若外症溃脓旬余，用白降条，极易全功。
妇女感染梅毒，病邪侵犯阳明经，导致乳房溃烂深凹如陷，完全不红肿疼痛，时常流出臭秽的清水，乳汁分泌依然通畅，据此可以辨别。
梅毒毒邪下注于三阴经（太阴、少阴、厥阴），腿部和小腿皮肤溃烂发黑或呈紫暗色，时常流淌臭水，伤口中有竖立的肉芽，凹凸不平如同镶嵌珍珠的形状，大小不一，称为“落底结毒”，极难彻底治愈。
在战乱持续已久的地方，必然有恶厉之气弥漫其间，加上马尿流入河流井水中，体质虚弱及过度劳累的人，容易受到这种毒气侵袭。毒气进入肺胃，浸淫于肌肉，通达于皮肤。起初出现小红疙瘩，逐渐变成像梅子李子大小的疮疡，臭烂翻花，里面有竖立的肉芽，这被称为“野杨梅”。这不是由精气传染而来的，治疗方法与梅毒疮相同，容易见效。
阴茎溃烂至一段段脱落直至平齐根部者，外用涂抹珠黄散，内服败毒方，逐渐可以收效。如果肿胀坚硬且臭烂，治疗无效者，难以痊愈。如果肿胀呈现猪肝颜色者，无法治愈。
霍乱症，头部额头和全身完全不发热，只有头晕烦闷，上吐下泻者。如果不吐不泻，只是腹痛剧烈，这是“搅肠痧”。如果是时令感受邪气，头面身体腹部都发热，医生必须用右手触摸按压病人的头部和胸腹部才能确诊。如果是女性患者，可以让其家中女性亲属代为触摸。
痈疽溃破流脓日久，患处时常流出稀脓，或流出清水，最终伤口难以愈合。或者伤口刚愈合不久又复发，必定是脓毒瘀结形成瘘管。使用降药条插入患处，贴上膏药，过七天后瘘管自然排出，再敷上生肌收口药物即可痊愈。所谓降药是由水银炼制而成的，其性质与砒霜相当，猛烈且具有腐蚀疼痛作用，不可轻易使用。年轻力壮者，可少量使用。若是幼儿老人及体质虚弱者，使用会产生变证。但如果疼痛剧烈，导致浮火上攻，口腔舌头和牙根糜烂者，使用生麦益阴煎（方剂见后）。凡是口腔中、眼边、耳中、鼻内，以及心窝、腰眼、阴茎、红筋聚集处，血瘤、气瘤，都绝对不可使用，否则关乎性命。历来只知道它的好处，不知道它的危害。现在有一种化险为夷的方法，用降药三分，生石膏七分，糯米饭汁捣碎调和做成药条，也能追拔恶腐组织并促进收口，内部适宜投用调养方剂。如果外部症状溃破流脓超过十天，使用白降条，极易取得全功。
Syphilis in women, affecting the Yangming channel, causes deep ulceration of the breasts resembling a depression, with no swelling or pain. There is intermittent discharge of foul-smelling clear fluid, while lactation remains normal; this distinguishes it from other conditions.
When syphilitic toxin sinks downward into the Three Yin channels (Taiyin, Shaoyin, Jueyin), the legs and shins become ulcerated, turning black or dark purple. Foul fluid oozes intermittently, with vertical granulation tissue protruding, creating an uneven surface resembling embedded pearls of varying sizes. This is termed "Luodi Jiedu" (Deep-set Condensed Toxin) and is extremely difficult to cure completely.
In regions where warfare has persisted for a long time, malignant pestilential Qi inevitably permeates the area. Combined with horse urine flowing into rivers and wells, individuals with deficient constitutions or those suffering from overwork are prone to infection. The toxin enters the Lung and Stomach, spreads through the muscles, and reaches the skin. It initially presents as small red papules, gradually enlarging to the size of plums or dates, becoming foul, ulcerated, and everted, with vertical granulation tissue inside. This is known as "Ye Yangmei" (Wild Bayberry). Not transmitted via essence or sexual contact, its treatment is identical to that of standard syphilitic chancres and yields good results easily.
If the penis ulcerates segmentally until detaching down to the root, apply Zhuhuang San externally and take Baidu Fang internally; gradual recovery is possible. If there is swelling, induration, and foul ulceration unresponsive to treatment, healing is unlikely. If the swelling resembles the color of pig liver, it is incurable.
In cases of Huoluan (Cholera-like syndrome), there is no fever on the forehead or throughout the body, only dizziness, irritability, vomiting, and diarrhea. If there is no vomiting or diarrhea but severe abdominal pain, it is classified as "Jiaochang Sha" (Intestine-Twisting Sha). In seasonal epidemic febrile diseases where the head, face, body, and abdomen all present with fever, the physician must palpate the patient's head and chest/abdomen with the right hand to confirm the diagnosis. For female patients, female relatives may perform the palpation.
For carbuncles and sores that have ulcerated and discharged pus for a long time, if the wound intermittently discharges thin pus or clear fluid and fails to heal, or heals briefly only to recur, it indicates that pus and toxin have stagnated and formed a fistula tract. Insert Jiangyao Tiao (Descendant Drug Strip) into the tract and apply a plaster. After seven days, the tract will naturally expel itself, after which application of wound-healing agents can effect a cure. Jiangyao is refined from mercury; its nature is equivalent to arsenic trioxide (Pishuang), being fierce, corrosive, and painful. It should not be used lightly. Young and robust individuals may use it in small amounts. However, in children, the elderly, or those with deficient constitutions, its use may cause adverse transformations. If pain is severe, causing floating fire to attack upward, leading to erosion of the mouth, tongue, and gums, Shengmai Yiyin Jian (Decoction to Generate Mai and Nourish Yin) (see formula below) should be used. It is absolutely contraindicated in the mouth, around the eyes, ears, nose, epigastrium, lumbar region, penis, areas of red vein aggregation, hemangiomas, and qi tumors, as misuse can be fatal. Historically, only its benefits were known, not its harms. A method to transform danger into safety now exists: mix 3 fen of Jiangyao with 7 fen of Gypsum Fibrosum (Shigao), pounded together with rice gruel juice to form strips. This can also extract necrotic tissue and promote healing, accompanied by internal administration of tonic formulas. If external ulceration and pus discharge have persisted for more than ten days, using Baijiang Tiao (White Descendant Strip) can achieve complete success easily.