论曰心疟者，内经谓令人烦心甚。欲得清水，反寒多不甚热，刺手少阴是也，盖心为神
舍，邪不可干，邪气干之，故烦心，其欲清水者，以心火内热故也，其反寒多不甚热者，内
热而外寒故也，治宜通心经利邪热则愈。
治心疟。常山丸方
常山（别捣一两） 桃仁（取陈者去双仁炒和皮捣一两） 铅丹（八钱细研） 豉（一
合炒令烟尽手捻可碎摊冷别捣）
上四味。捣研为末，炼蜜和再捣千杵，丸如梧桐子大，每服十五丸，鸡鸣时空心酒下，
欲发时再服十五丸，其日不得梳洗，发过方可饮食。
治心疟烦心甚，欲得清水，反寒多不甚热。常山汤方
常山（锉一两） 栀子仁（七攻） 石膏（研碎一两） 乌梅（去核炒七枚） 鳖甲（醋
浸炙去裙 一两） 甘草（炙锉一分） 豉（微炒一合） 蜀漆（三分）
上八味。粗捣筛，每服三钱匕，水一盏，入竹叶三片，锉碎，煎至七分去滓，未发前
温服，临发再服。
治心疟。熊胆丸方
砒霜（研半两） 丹砂（研） 麝香（研） 雄黄（研） 熊胆（各二两）
上五味。以熊胆和前四味为丸，如绿豆大，发日空心冷水下两丸，临发时再服一丸，皆
以冷饭压，或当日便止，或大作乃瘥，如欲吐，即以暖水下之，当吐出痰涎，即瘥。
治心疟。黄连散方
黄连（去须）
上一味。捣罗为散，发前以酒和三指撮服。
论述说：所谓心疟，是《内经》中提到的使人心中极度烦闷的病证。患者想要喝冷水，但反而怕冷多而发热轻，治疗应当针刺手少阴心经的穴位。这是因为心是神志居住的地方，邪气难以侵犯；一旦邪气侵犯，就会导致心烦。患者想喝冷水，是因为心火内热所致；患者反而怕冷多而发热轻，是因为内部有热而外部表现为寒。治疗适宜疏通心经，通利邪热，病即可痊愈。
治疗心疟的常山丸方：
常山（单独捣碎一两）、桃仁（选用陈年的，去掉双仁，炒制后去皮捣碎一两）、铅丹（八钱，细细研磨）、豆豉（一合，炒至烟尽，用手能捻碎，摊凉后单独捣碎）。
以上四味药，捣碎研成细末，用炼过的蜂蜜调和，再捣一千杵，制成梧桐子大小的药丸。每次服用十五丸，在鸡鸣时分空腹用酒送服，在症状发作前再服用十五丸。当天不得梳头洗澡，症状发作过后才可以饮食。
治疗心疟心中极度烦闷、想要喝冷水、反而怕冷多而发热轻的常山汤方：
常山（锉碎一两）、栀子仁（七枚）、石膏（研碎一两）、乌梅（去核炒制七枚）、鳖甲（醋浸后炙烤，去除裙边一两）、甘草（炙烤后锉碎一分）、豆豉（微炒一合）、蜀漆（三分）。
以上八味药，粗捣筛过，每次取三钱匕，用水一盏，加入竹叶三片，锉碎，煎煮至七分水量，去渣滓，在症状发作前温服，临发作时再服一次。
治疗心疟的熊胆丸方：
砒霜（研半两）、丹砂（研）、麝香（研）、雄黄（研）、熊胆（各二两）。
以上五味药，用熊胆将前四味药和匀制成丸药，如绿豆大小。发病当天空腹用冷水送服两丸，临发作时再服一丸，都用冷饭压住药力。有的当天就停止发作，有的剧烈发作后才痊愈。如果引起呕吐，就用温水将其压下，应当吐出痰涎，病即痊愈。
Commentary states: Regarding Heart Malaria (Xin Nue), the *Neijing* describes it as causing severe mental restlessness. The patient desires cold water, yet experiences more chills than fever. Treatment involves needling the Hand-Shaoyin (Heart) meridian. This is because the Heart is the residence of the Spirit (Shen); pathogenic factors cannot easily invade it. When pathogenic factors do invade, they cause mental restlessness. The desire for cold water arises from internal Heat of Heart Fire. The manifestation of more chills and less fever occurs because there is internal Heat while the exterior presents with Cold. Treatment should focus on unblocking the Heart meridian and draining pathogenic Heat to achieve a cure.
Formula for Chanshan Pill (Changshan Wan) to treat Heart Malaria:
Chanshan (Stemona Root, *Stemonae Radix*) [1 liang, pounded separately], Taoren (Peach Kernel, *Persicae Semen*) [1 liang, select aged kernels, remove double-kernel ones, stir-fry, remove skin, and pound], Qiandan (Lead Oxide, *Lithargyri Pulvis*) [8 qian, finely ground], Chishao (Fermented Soybean, *Sojae Preparata*) [1 he, stir-fry until smoke ceases, crushable by hand, spread to cool, then pounded separately].
The above four ingredients are pounded and ground into powder. Mix with refined honey, then pound another thousand times. Form pills the size of sophora seeds. Take 15 pills each time, administered with wine on an empty stomach at the hour of Ji Ming (3-5 AM). Take another 15 pills just before the onset of symptoms. On that day, avoid combing hair or bathing; food and drink may be resumed only after the episode has passed.
Formula for Chanshan Decoction (Changshan Tang) to treat Heart Malaria with severe mental restlessness, desire for cold water, more chills than fever:
Chanshan (*Stemonae Radix*) [1 liang, cut into small pieces], Zhizi Ren (Gardenia Seed, *Gardeniae Fructus*) [7 units], Shigao (Gypsum Fibrosum, *Gypsi Fibrosum*) [1 liang, crushed], Wumei (Mume Fruit, *Prunae Mume Fructus*) [7 units, pitted and stir-fried], Biejia (Carapax et Plastrum Testudinis, *Testudinis Carapax et Plastrum*) [1 liang, soaked in vinegar, roasted, remove skirt-like edges], Gancao (Licorice Root, *Glycyrrhizae Radix et Rhizoma*) [1 fen, roasted and cut], Chishao (*Sojae Preparata*) [1 he, lightly stir-fried], Shuqi (Herba Pteridis Quercifoliae, *Pteridis Quercifoliae Herba*) [3 qian].
The above eight ingredients are coarsely pounded and sifted. Take 3 qian bi per dose, add 1 sheng of water and 3 slices of Zhu Ye (Bamboo Leaf, *Phyllostachys Viridis Folium*), cut into pieces. Decoct until 0.7 sheng remains, strain off the dregs. Take warm before the onset of symptoms, and again immediately prior to onset.
Formula for Xiondan Pill (Xiondan Wan) to treat Heart Malaria:
Pishuang (Arsenic Trioxide, *Arsenici Trioxidum*) [0.5 liang, ground], Dansha (Cinnabar, *Cinnabaris*), Shexiang (Moschus, *Moschi Feratum*), Xionghuang (Realgar, *Realgar), Xiondan (Ursi Fel, *Ursi Fel*) [2 liang each].
The above five ingredients are mixed using Xiondan to form pills the size of mung beans. On the day of onset, take 2 pills on an empty stomach with cold water. Just before onset, take 1 pill. In both instances, suppress the drug's action with cold cooked rice. The attack may cease on the same day or only after a severe outbreak does recovery occur. If vomiting is induced, administer warm water to swallow it down. Phlegm and saliva should be vomited out, leading to recovery.
Formula for Huanglian Powder (Huanglian San) to treat Heart Malaria:
Huanglian (Coptis Rhizome, *Coptidis Rhizoma*) [remove roots].
The above single ingredient is pounded and sieved into a powder. Before onset, mix with wine and take a quantity held between three fingers (approx. 3-5 grams).