味辛，大热，有大毒。主痈肿，风痹，历节，腰脚疼冷寒热，鼠 ，又堕胎。《药性
云∶使。能治冷风湿痹，大风，筋骨挛急。陶隐居云∶今医家以疗香港脚多验。陈脏器云
治遍身风疹。冷酒调服。《图经》∶乌头、乌喙生朗陵山谷，天雄生少室山谷，附子、侧子
生犍为山谷及广汉，今并出蜀土。畏恶∶与附子同。
味辛，微温，有大毒。主风湿，丈夫肾湿阴囊痒，寒热历节，掣引腰痛不能行步，痈
肿脓结，又堕胎。《药性论》云∶使。忌∶豉汁。味苦辛，大热。治男子肾气衰弱，阴汗，
主疗风温，湿邪痛，寒热痈肿不消者。畏恶使∶并与乌头同。
味辛，平。生，微寒，熟温。有毒。主伤寒寒热，心下坚，下气，喉咽肿痛，头眩胸
胀，咳逆，肠鸣，止汗，消心腹胸膈痰热满结，咳嗽上气，心下急痛坚痞，时气呕逆，消痈
肿，堕胎，疗痿黄。《药性论》云∶使。能消痰涎，开胃健脾，止呕吐，去胸中痰满，下
气，主颏结。新生者摩涂痈肿不消，能除瘤瘿，气虚有痰气，加而用之。日华子云∶味 辛
。治吐食反胃，霍乱转筋，肠腹冷，痰疟。射干为使。忌∶海藻、饴糖。恶∶皂荚。畏∶
雄黄、生姜、干姜、秦皮、龟甲。反∶乌头。
味苦，寒、无毒。主下瘀血，血闭，寒热，破症瘕积聚，留饮宿食，荡涤肠胃，推陈
致新，通利水谷，调中化食，安和五脏，平胃下气，除痰实，肠间结热，心腹胀满，女子寒
血闭胀，小腹痛，诸老血留结。《药性论》云∶使。去寒热，结聚宿食，利大小肠，贴热毒
泄
用
上
硝
【侧子】味辛，性大热，有大毒。主治痈肿，风痹，历节病（关节疼痛游走不定），腰脚冷痛及寒热交替，鼠瘘（淋巴结结核），并能导致流产。《药性论》记载：以它为使药。能治疗冷风湿痹，大风（麻风病等严重风疾），筋骨拘挛紧急。陶隐居说：当今医生用它治疗脚气病多有效验。陈藏器说：能治疗遍身风疹。用冷酒调服。《图经本草》记载：乌头、乌喙生长在朗陵的山谷中，天雄生长在少室的山谷中，附子、侧子生长在犍为的山谷及广汉，现在都出产于蜀地。畏恶关系：与附子相同。
【附子】味辛，性微温，有大毒。主治风湿，男子肾虚湿盛导致的阴囊瘙痒，寒热交替的历节病，牵引腰痛不能行走，痈肿脓结，并能导致流产。《药性论》记载：以它为使药。禁忌：豆豉汁。味苦辛，性大热。治疗男子肾气衰弱，阴部出汗，主治风温，湿邪引起的疼痛，寒热痈肿不消退者。畏恶使关系：都与乌头相同。
【射干】味辛，性平。生用性微寒，熟用性温。有毒。主治伤寒引起的寒热，心下坚硬，降气，喉咽肿痛，头晕目眩胸胀，咳嗽气逆，肠鸣，止汗，消除心腹胸膈部的痰热满结，咳嗽气上逆，心下急痛坚痞，时行疫病引起的呕吐逆气，消痈肿，导致流产，治疗萎黄病。《药性论》记载：以它为使药。能消除痰涎，开胃健脾，止呕吐，去除胸中痰满，降气，主治颏下结块。新鲜的射干研磨涂抹在痈肿上不消退处，能消除瘤瘿。气虚有痰气的人，加入使用。日华子说：味辛。治疗吐食反胃，霍乱转筋，肠腹冷痛，痰疟。以它为引经药的是射干。禁忌：海藻、饴糖。厌恶：皂荚。畏惧：雄黄、生姜、干姜、秦皮、龟甲。相反：乌头。
【大黄】味苦，性寒，无毒。主治下部瘀血，血闭，寒热，破除症瘕积聚（腹部肿块），排除留饮和宿食，荡涤肠胃，推陈出新，通利水谷，调和脾胃消化食物，安和五脏，平胃降气，去除痰实，清除肠间结热，心腹胀满，女子因寒导致的血闭胀满，小腹痛，各种陈旧性瘀血留结。《药性论》记载：以它为使药。去除寒热，解除结聚宿食，利大小肠，贴敷用于热毒泄泻。
[Cezi (Side Root of Aconitum)] Pungent in flavor, excessively hot in nature, possessing great toxicity. It primarily treats carbuncles and swellings, wind-bi syndrome, li-jie disease (painful obstruction with wandering joint pain), cold pain in the waist and legs alternating with fever, shu-lou (scrofula/lymph node tuberculosis), and can induce abortion. *Yao Xing Lun* states: It serves as a guiding drug (shi). It can treat cold-damp wind-bi, da-feng (severe wind diseases such as leprosy), and spasm/tightness of sinews and bones. Tao Hongjing said: Contemporary physicians use it to treat hong-gang-jiao (foot qi/podagra) with frequent efficacy. Chen Zangqi stated: It treats generalized wind-rash. It is taken mixed with cold wine. *Tu Jing* records: Wu-tou and Wu-hui grow in the valleys of Langling; Tian-xiong grows in the valleys of Shaoshi; Fu-zi and Ce-zi grow in the valleys of Qianwei and Guanghan; currently, all are produced in Shu territory. Mutual aversion and incompatibility: Same as Fu-zi.
[Fuzi (Lateral Root of Aconitum)] Pungent in flavor, slightly warm in nature, possessing great toxicity. It primarily treats wind-damp, scrotal itching due to kidney dampness in men, li-jie disease with alternating chills and fever, lumbar pain radiating that prevents walking, carbuncles and swellings with pus accumulation, and can induce abortion. *Yao Xing Lun* states: It serves as a guiding drug (shi). Contraindications: Dou chi juice (fermented soybean juice). Bitter and pungent in flavor, excessively hot in nature. It treats weakness of kidney qi in men, sweating in the genital area, wind-warmth, pain caused by damp pathogenic factors, and persistent carbuncles and swellings with alternating chills and fever. Mutual aversion and incompatibility: Same as Wu-tou.
[Shegan (Rhizome Belamcandae)] Pungent in flavor, neutral in nature. Raw form is slightly cold; cooked form is warm. Toxic. It primarily treats chills and fever from shang-han (cold damage), hardness below the heart, directs qi downward, sore throat and swelling, dizziness and chest distension, cough with rebellious qi, borborygmus, stops sweating, resolves phlegm-heat fullness and accumulation in the heart, abdomen, and diaphragm, cough with rebellious qi, acute pain and hard masses below the heart, vomiting and regurgitation from seasonal epidemics, reduces carbuncles and swellings, induces abortion, and treats wei-huang (sallow complexion/wasting-thirst). *Yao Xing Lun* states: It serves as a guiding drug (shi). It can resolve phlegm-saliva, open the stomach and strengthen the spleen, stop vomiting, remove fullness of phlegm in the chest, direct qi downward, and treat nodules under the chin. Fresh Shegan applied topically can eliminate persistent carbuncles and reduce tumors/goiters. For those with qi deficiency and phlegm-qi stagnation, it is added for use. Ri Huazi stated: Pungent in flavor. It treats projectile vomiting and reverse flow, hu-luan (cholera-like disorder) with muscle cramps, cold in intestines and abdomen, and phlegmatic malaria. The drug that acts as its guide is Shegan itself. Contraindications: Hai-zao (Sargassum), Yi-tang (malt sugar). Aversion: Zao-jia (Gleditsia sinensis fruit spine). Fear: Xiong-huang (Realgar), Sheng-jiang (Fresh Ginger), Gan-jiang (Dried Ginger), Qin-pi (Fraxinus bark), Gui-jia (Carapace Testudinis). Opposition: Wu-tou.
[Dahuang (Radix et Rhizoma Rhei)] Bitter in flavor, cold in nature, non-toxic. It primarily treats blood stasis in the lower jiao, blood closure, chills and fever, breaks up zheng-jia accumulations (abdominal masses), expels retained fluids and old food retention, purges the stomach and intestines, pushes out the old to bring forth the new, promotes the passage of water and grain, harmonizes the middle jiao and transforms food, calms and harmonizes the five zang organs, levels the stomach and directs qi downward, removes phlegm-solidities, clears heat binding in the intestines, relieves abdominal fullness and distension, treats female blood closure and distension due to cold, hypogastric pain, and various forms of old blood retention and knotting. *Yao Xing Lun* states: It serves as a guiding drug (shi). It removes chills and fever, resolves accumulations and old food retention, benefits the large and small intestines, and is applied externally for heat-toxin diarrhea.