蟾酥条（即前蟾酥丸作条捏饼用之）
琥珀蜡矾丸 玉红膏 如意金黄散 护心散 托里消毒散（见肿疡门）
八珍汤 益气养荣汤 加减八味丸 人参养荣汤（见溃疡门）
珍珠散（下疳门）
冰蛳散（瘰 门）
夫脱疽者，外腐而内坏也。此因平昔浓味膏粱熏蒸脏腑，丹石补药消烁肾水，房劳过度，气竭精伤，
……多致阳精煽惑，淫火猖狂，其蕴蓄于脏腑者，终成燥热火症，其毒积于骨髓者，终为疽毒阴疮。诚
为巧人行拙，谁防祸起萧墙，智者多愚，自谓喜从天降，罔顾后日也；骨枯髓涸，脏败腑亡，方知今日罹殃有
故，解脱无方。凡患此者，多生于手足，故手足乃五脏枝干，疮之初生，形如粟米，头便一点黄泡，其皮犹如
煮熟红枣，黑气侵漫，相传五指，传遍上至脚面，其疼如汤泼火燃，其形则骨枯筋练，其秽异香难解，其命仙
方难活。故谓血死心败，筋死肝败，肉死脾败，皮死肺败，骨死肾败。此五败者，虽有灵丹竟丧命而已。是生
此疾者，死生付于度外。孙真人曰∶
在肉则割，在指则切，即此病也。治之得早，乘其未及延散时，用头发十余根缠患指本节尽处，绕扎十余转，
渐渐紧之，毋得毒瓦斯攻延良肉。随用蟾酥饼，放原起粟米头上，加艾灸至肉枯疮死为度。次日本指尽黑，方用
利刀寻至本节缝中，将患指徐顺取下，血流不住，用金刀如圣散止之，余肿以妙贴散敷之。次日倘有黑气未尽，
单用蟾酥锭研末掺之膏盖，黑气自退。患上生脓，照常法用玉红膏等药生肉护骨完口，此为吉兆；内服滋
肾水、养气血、健脾安神之剂。若内无变症，外无混杂，此十中可保其三、四矣。若割取之后，黑色仍漫，痛
肿尤甚，败恶无脓，口干舌硬，精神不爽，食不知味者终死。凡治此，不可一己医治，必与高明众议，听患者
愿情割取，况此症首尾吉凶，变驳难定，故不可轻易用之；又有形似而来非，穴真而受异，详注在后，宜参观
之。
蟾酥条（即把前文提到的蟾酥丸做成条状，捏成饼形使用）
琥珀蜡矾丸、玉红膏、如意金黄散、护心散、托里消毒散（见肿疡门章节）
八珍汤、益气养荣汤、加减八味丸、人参养荣汤（见溃疡门章节）
珍珠散（见下疳门章节）
冰蛳散（见瘰疬门章节）
所谓脱疽，是指外部腐烂而内部坏死的病症。这通常是因为平时饮食过于浓厚油腻，熏蒸脏腑；或者服用丹石类补药，耗损肾水；又或因房事过度，导致气竭精伤……往往致使阳精被煽动惑乱，淫火猖狂肆虐。蕴蓄在脏腑中的邪气，最终形成燥热火症；积聚在骨髓中的毒气，最终成为疽毒阴疮。这真是聪明人做笨事，谁能防备祸患从内部兴起？智者多犯愚行，自以为喜事从天而降，不顾及日后的灾祸。等到骨枯髓干，脏腑败亡，才知道今日遭受灾殃是有原因的，但那时已无解脱之法。
凡是患这种病的，多生于手足部位。因为手足是五脏的枝干。疮疡初生时，形状像粟米，顶端有一个黄泡，皮肤颜色如同煮熟的红枣，随后黑气蔓延，传染至五指，甚至传遍整个脚面。疼痛剧烈，如同热水泼洒或烈火燃烧；形体表现为骨枯筋挛；气味秽浊异香难解；即使有神仙方也难以救活。所以说，血死则心败，筋死则肝败，肉死则脾败，皮死则肺败，骨死则肾败。这五种败象出现后，即使有灵丹妙药也只会丧命。因此，患此疾的人，生死只能听天由命。
孙真人说：“病灶在肌肉就切除肌肉，病灶在手指就截断手指”，指的就是这种病。治疗要趁早，在其尚未扩散蔓延时，用十几根头发缠绕在患病手指的本节尽头处，绕扎十余圈，逐渐收紧，不要让毒瓦斯攻延到健康的肌肉上。随即用蟾酥饼，放置在最初长出粟米样的疮头上，加艾炷艾灸，直到肉枯疮死为止。第二天，如果整个手指完全变黑，才用锋利的刀沿着本节缝隙，将患指慢慢顺向取下。此时血流不止，用金刀如圣散止血，其余肿胀用妙贴散敷治。次日如果有黑气未完全消退，单用蟾酥锭研成末撒在患处，盖上膏药，黑气自然会退去。患处生出脓液后，按常规方法使用玉红膏等药物生肌长肉、保护骨骼、愈合伤口，这是吉兆；同时内服滋补肾水、调养气血、健脾安神的药剂。如果体内没有变证，体外没有混杂症状，十个人中可以保住三四个。如果在割取之后，黑色仍然蔓延，肿痛更加严重，创口败坏无脓，口干舌硬，精神萎靡，饮食不知滋味，则最终死亡。
凡治疗此病，不可仅凭一人意见医治，必须与高明医生共同商议，并听取患者愿意截肢的意愿。况且此症从头到尾吉凶难定，变化驳杂，所以不可轻易使用手术；又有外形相似但实质不同，穴位真实但病因各异的情况，详细注释在后面，宜参考查看。
Chan Su Tiao (Cinnabar Toad Venom Strips, i.e., the previously mentioned Chan Su Wan [Toad Venom Pill] shaped into strips and pressed into cakes for use)
Hupo Lafan Wan [Amber Wax Alum Pill], Yuhong Gao [Jade Red Ointment], Ruyi Jinhuang San [Ruyi Golden Yellow Powder], Huxin San [Heart-Protecting Powder], Tuoli Xiaodu San [Interior-Supporting and Toxin-Expelling Powder] (see chapter on Swollen Ulcers)
Bazhen Tang [Eight-Treasure Decoction], Yiqi Yangrong Tang [Qi-Nourishing and Blood-Enriching Decoction], Jiaban Bawei Wan [Modified Eight-Flavor Pill], Renshen Yangrong Tang [Ginseng Qi-Nourishing and Blood-Enriching Decoction] (see chapter on Ulcerated Lesions)
Zhenzhu San [Pearl Powder] (see chapter on Chancre)
Bingsi San [Ice Snail Powder] (see chapter on Scrofula)
Tuojie [Dry Gangrene/De-jie] refers to a condition where the exterior rots while the interior necroses. This is caused by habitual consumption of rich, greasy foods that steam and affect the Zang-Fu organs; or the use of Dan-Shi [cinnabar and stone] tonics that consume Kidney Water; or excessive sexual activity leading to exhaustion of Qi and injury of Essence... Often resulting in the stirring and confusion of Yang Essence, and the rampant flare-up of Yin Fire. The pathogenic factors accumulated within the Zang-Fu eventually transform into Dry Heat-Fire syndromes; the toxins accumulated in the bone marrow ultimately become Ju-Du [carbuncle toxin] and Yin Chuang [Yin sores]. It is indeed like a clever person acting clumsily; who can guard against disaster arising from within? The wise often act foolishly, believing joy comes from heaven, disregarding future calamities. Only when bones wither, marrow dries up, and Zang-Fu organs fail does one realize the cause of today's suffering, yet there is no way to escape it at that point.
Those afflicted with this disease mostly suffer on the hands and feet, as these are the branches and trunks of the Five Zang organs. When the sore first appears, its shape resembles millet grains, with a yellow blister at the head. The skin resembles a boiled red date. Black qi then spreads, affecting all five fingers, and may extend up to the top of the foot. The pain is severe, like hot water poured on fire or burning flames. The physical form shows withered bones and contracted tendons. The odor is foul and difficult to resolve. Even immortal prescriptions cannot save life. Thus, it is said: if blood dies, Heart fails; if tendons die, Liver fails; if flesh dies, Spleen fails; if skin dies, Lung fails; if bones die, Kidney fails. With these five failures, even miraculous pills will only result in death. Therefore, those born with this illness leave their life and death to fate.
Sun Simiao said: "If the lesion is in the muscle, excise the muscle; if in the finger, amputate the finger." This refers to this disease. Treatment must be early. While the pathogen has not yet spread, use more than ten strands of hair to wrap tightly around the proximal interphalangeal joint of the affected finger, winding it over ten times, gradually tightening it, so that toxic vapors do not invade healthy flesh. Then, place a Chan Su Bing [Toad Venom Cake] on the original millet-like spot, apply moxibustion until the flesh is necrotic and the sore dies. The next day, if the entire finger turns black, use a sharp knife to locate the joint seam, and gently remove the affected finger. If bleeding persists, use Jindao Rusheng San [Golden Knife Like Sage Powder] to stop it, and apply Miaotie San [Wonderful Adhesion Powder] to the remaining swelling. If black qi remains on the second day, grind Chan Su Ding [Toad Venom Ingot] into powder, sprinkle it on the lesion, cover with an ointment, and the black qi will recede naturally. Once pus forms, follow standard methods using Yuhong Gao [Jade Red Ointment] and other medicines to generate flesh, protect bone, and close the wound; this is an auspicious sign. Internally, administer decoctions that nourish Kidney Water, tonify Qi and Blood, strengthen the Spleen, and calm the Spirit. If there are no internal complications or external mixed symptoms, three or four out of ten patients may survive. However, if after amputation the blackness still spreads, pain and swelling worsen, the wound is necrotic without pus, the mouth is dry with a stiff tongue, spirit is listless, and taste is lost, death is inevitable.
In treating this disease, one should not rely on personal opinion alone but must consult with eminent physicians and respect the patient's willingness to undergo amputation. Given that the prognosis of this condition varies and changes are unpredictable, surgery should not be used lightly. There are also cases that resemble this disease but are different in nature, or involve true acupoints but different etiologies; detailed notes are provided later for reference.